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Sang-hyeop Lee

Yonsei University · Medicine

About the Lab

Professor Sang-hyeop Lee's research lab specializes in clinical ophthalmology and biomedical engineering, with a focus on glaucoma management, ocular infections, and advanced biomaterials. The lab investigates long-term outcomes of glaucoma surgical interventions such as Ahmed valve implantation, explores complex corneal infections involving multidrug-resistant organisms, and develops functionalized materials for improved energy performance. Research spans from clinical trials and patient outcomes to material synthesis and thermophysical characterization, reflecting a strong translational approach.

glaucoma surgerycorneal infectionAhmed valvebiomaterialsenergy materials

Research Overview

Papers
132
Total Citations
1,503
Papers (5y)
42
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
42total
2022
2023
2024
2025
2026
Citations per year (5y)
264total
20222023202420252026

Selected Papers

15
1
Article|50 citations·2023
Combination Moderate-Intensity Statin and Ezetimibe Therapy for Elderly Patients With Atherosclerosis
Sang‐Hyup Lee, Yong‐Joon Lee, Jung Ho Heo, Seung‐Ho Hur, Hyun Hee Choi, Kyung-Jin Kim, Ju Han Kim, Ju Han Kim, Keun Ho Park, Jung Hee Lee, Yu Jeong Choi, Seung‐Jun Lee
SJR Q1Journal of the American College of CardiologyOA
SurgeryMedicine
2
Article|20 citations·2017
Morphological change and photocatalytic activity of titanium phosphates
Youngyong Kim, Hee Chan Kim, Jaesang Lee, Sang‐Hyup Lee, Ki-Young Kwon
SJR Q2Journal of Photochemistry and Photobiology A Chemistry
Biomedical EngineeringEngineering
3
Article|14 citations·2016
Thermo-physical characteristics of nickel-coated aluminum powder as a function of particle size and oxidant
Sang‐Hyup Lee, Kwanyoung Noh, Jihwan Lim, Woong Yoon
SJR Q1Chinese Journal of Mechanical Engineering
Mechanics of MaterialsEngineering
4
Article|8 citations·2024
Development of Clinically Validated Artificial Intelligence Model for Detecting ST-segment Elevation Myocardial Infarction
Sang‐Hyup Lee, Kyu Lee Jeon, Yong‐Joon Lee, Seng Chan You, Seung‐Jun Lee, Sung‐Jin Hong, Chul‐Min Ahn, Jung‐Sun Kim, Byeong‐Keuk Kim, Young‐Guk Ko, Donghoon Choi, Myeong‐Ki Hong
SJR Q1Annals of Emergency Medicine
Cardiology and Cardiovascular MedicineMedicine
5
Article|8 citations·2025
Intravascular Ultrasound-Guided vs Angiography-Guided Drug-Coated Balloon Angioplasty in Patients With Complex Femoropopliteal Artery Disease
Seung‐Jun Lee, Seung‐Jun Lee, Tae‐Hoon Kim, Jae‐Hwan Lee, Chul‐Min Ahn, Sang‐Hyup Lee, Sang‐Hyup Lee, Yong‐Joon Lee, Byeong‐Keuk Kim, Myeong‐Ki Hong, Yangsoo Jang, Ha-Wook Park
SJR Q1JACC: Cardiovascular InterventionsOA
SurgeryMedicine
6
Article|8 citations·2007
난치성 녹내장에서 아메드 방수유출장치 삽입술의 효과
이상협, 마경탁, 홍영재

목적 : 난치성 녹내장 환자에서 아메드 방수유출장치 삽입술의 장기 임상결과를 살펴보고, 일차와 이차 삽입술의 성공률을 비교하고자 한다. 대상과 방법 : 1995년 3월부터 2004년 9월까지 아메드 방수유출장치 삽입술을 시행받은 101명의 환자, 101안을 대상으로 후향적으로 연구하였다. 수술의 성공은 (1) 술 후 약물의 사용과 관계없이 5~21 mmHg의 안압이 유지되면서 안압이 술 전의 30% 이상 감소하고, (2) 안압이나 합병증으로 인한 시력감소가 없으며, (3) 추가적 녹내장수술을 시행하지 않은 것으로 정의하였다. 임상기록을 바탕으로 안압, 녹내장 약물의 투여, 합병증을 조사하였으며, Kaplan-Meier 생존분석을 이용하여 수술의 성공률을 비교하였다. 결과 : 술 후 1년, 3년, 5년, 7년의 누적 성공률은 일차 수술군에서 57.6%, 46.7%, 39.7%, 39.7%, 이차 수술군에서 67.8%, 58.1%, 52.4%, 43.5%였으며 두 군간의 통계학적으로 유

7
Article|4 citations·2025
Validation of Intravascular Ultrasound–Defined Optimal Stent Expansion Criteria for Favorable 1-Year Clinical Outcomes
Sang‐Hyup Lee, Sang‐Hyup Lee, Xiaoping Jin, Yong‐Joon Lee, Jing Kan, Zhen Ge, Seung‐Jun Lee, Seung‐Jun Lee, Sung‐Jin Hong, Chul‐Min Ahn, Jung‐Sun Kim, Byeong‐Keuk Kim
SJR Q1JACC: Cardiovascular Interventions
SurgeryMedicine
8
Article|4 citations·2025
Optical coherence tomography-guided stent optimization for complex coronary lesions: the OCCUPI trial
Seung‐Jun Lee, Seung‐Jae Lee, Sung‐Jin Hong, Deok‐Kyu Cho, Jin Won Kim, Sang Min Kim, Seung‐Ho Hur, Jung Ho Heo, Ji‐Yong Jang, Jin Sin Koh, Hoyoun Won, Jun‐Won Lee
SJR Q1European Heart Journal

BACKGROUND AND AIMS: This study evaluated the incidence, determinants, and clinical impact of stent optimization after optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) for complex lesions. METHODS: From the OCCUPI randomized trial investigating the impact of OCT guidance compared to angiography guidance in complex lesions, patients who underwent OCT-guided PCI with post-stenting OCT evaluations were enrolled and classified into two groups based on whether they m

SurgeryMedicine
9
Article|4 citations·2022
Adult-onset MELAS syndrome in a 51-year-old woman without typical clinical manifestations: a case report
Sang‐Hyup Lee, Chan Joo Lee, Dongju Won, Seok‐Min Kang
SJR Q3European Heart Journal - Case ReportsOA

Abstract Background Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome is a multi-organ disorder resulting from mitochondrial DNA (mtDNA) mutations. We report a case of suspected MELAS syndrome that progressed to left ventricular dysfunction 24 years after an initial diagnosis of atrioventricular block (AVB). Case summary A 51-year-old woman was referred to heart failure clinic because of dyspnoea on exertion and progressive cardiomegaly. She had a dua

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|4 citations·2007
반복각막진무름 후 혼합 세균각막염 1례
이상협, 김태임, 정소향, 정재림, 정성근, 김응권

목적 : 반복각막진무름이 있는 환자에서 Coagulase negative Staphylococcus와 Stenotrophomonas maltophilia에 의해 혼합감염된 각막염 1례를 경험하였기에 이를 보고하는 바이다. 대상과 방법 : 29세 여환이 좌안의 1달동안 치유되지 않은 각막궤양으로 의뢰되었다. 결과 : 내원 당시 좌안 최대교정시력은 0.025 이었고, 각막의 6 시방향에 2×2 mm의 각막간질침윤 및 각막내피반이 관찰되었다. 배양검사 후 5% cefazolin, 1.4% tobramycin, 3.3% vancomycin, 0.125% amphotericin, NatacynⓇ을 점안하였으나, 배양검사에서 균은 동정되지 않았고, 병변의 악화가 관찰되어 결막편 시술을 시행하였다. 결막편이식후 병변의 호전이 없어 시행한 재배양검사상 Coagulase negative Staphylococcus와 Stenotrophomonas maltophilia가 동정되었으며, 항생제 감수성 검

11
Article|4 citations·2015
Fabrication and Thermophysical Properties of Nickel-coated Aluminum Powder by Electroless Plating
Sang‐Hyup Lee, Woongsup Yoon, Kwanyoung Noh, Jihwan Lim, Do‐Hyung Lee, Changkee Kim
53rd AIAA Aerospace Sciences Meeting

To improve the ignitability of high energy aluminum powder, in this study, natural oxide films (alumina, Al2O3) were chemically removed and nickel coatings were deposited using an electroless method for nickel plating. The time-dependent degree of nickel deposition was confirmed qualitatively and quantitatively through surface analysis using scanning electron microscopy/energy dispersive spectroscopy. To characterize the nickel coatings, we also conducted elemental analysis by using X-ray diffra

Mechanics of MaterialsEngineering
12
Article|3 citations·2023
Comparison of Intracardiac Echocardiography Versus Transesophageal Echocardiography for Guidance During Transcatheter Aortic Valve Replacement
Sang‐Hyup Lee, Seunguk Oh, Young‐Guk Ko, Yong‐Joon Lee, Seung‐Jun Lee, Sung‐Jin Hong, Chul‐Min Ahn, Jung‐Sun Kim, Byeong‐Keuk Kim, Kyu‐Yong Ko, Iksung Cho, Chi Young Shim
SJR Q2Korean Circulation JournalOA

ICE was comparable to TEE for guidance during TAVR for the composite clinical efficacy outcome, with similar incidences of moderate-to-severe PVR, new permanent pacemaker implantation, and major bleeding. These results suggest that ICE could be a safe and effective alternative echocardiographic modality to TEE for guiding TAVR.

Cardiology and Cardiovascular MedicineMedicine
13
Article|3 citations·2015
A Steam-Plasma Igniter for Aluminum Powder Combustion
Sang‐Hyup Lee, Kwanyoung Noh, Jihwan Lim, Woong Yoon
SJR Q3Plasma Science and Technology

High-temperature ignition is essential for the ignition and combustion of energetic metal fuels, including aluminum and magnesium particles which are protected by their high-melting-temperature oxides. A plasma torch characterized by an ultrahigh-temperature plasma plume fulfills such high-temperature ignition conditions. A new steam plasma igniter is designed and successfully validated by aluminum power ignition and combustion tests. The steam plasma rapidly stabilizes in both plasma and steam

Mechanics of MaterialsEngineering
14
Article|3 citations·2024
Optimal antithrombotic strategy in patients with atrial fibrillation beyond 1 year after drug-eluting stent implantation: Design and rationale of the randomized ADAPT AF-DES trial
Sang‐Hyup Lee, Seung‐Jun Lee, Jung Ho Heo, Sung Gyun Ahn, Joon-Hyoung Doh, Sanghoon Shin, Jaemin Shim, Ae‐Young Her, Byung Gyu Kim, Sang Wook Lim, Taek‐Geun Kwon, Kyounghoon Lee
SJR Q1American Heart Journal
Cardiology and Cardiovascular MedicineMedicine
15
Article|3 citations·2007
폐기물 소각시설에서 발생되는 수은화합물 배출거동연구
이상협, 박규식, 이주형, 장하나, 김정훈, 서용칠

Emission sampling and analysis of mercury at inlet and outlet of air pollution control devices (APCDs) have been conducted to provide information on mercury speciation, mass distribution and removal. Four municipal waste incinerators and two industrial waste incinerators, each with dry and wet types of APCDs, and two cement kilns were selected to measure mercury concentrations mainly at Stacks, as well as selected locations between the APCDs. Gaseous sampling was implemented in accordance with t

Research Areas

Cardiology and Cardiovascular MedicineSurgeryBiophysicsBiomedical EngineeringMechanics of MaterialsMolecular Biology

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