SeongChan Yeon
Seoul National University · Medicine
About the Lab
Professor SeongChan Yeon's research lab focuses on veterinary and translational biomedical research, with a strong emphasis on animal welfare, regenerative medicine, and wildlife health. The lab investigates the physiological and behavioral impacts of housing and management practices on domestic animals—particularly pregnant mares—while also exploring stem cell biology, especially the immunogenic properties of umbilical cord blood-derived mesenchymal stem cells. Additionally, the lab examines the ecological and health consequences of wildlife rehabilitation, particularly on the gut microbiome and antibiotic resistance in wild migratory birds. These interconnected research directions highlight a commitment to improving animal health across domestic, clinical, and conservation contexts.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Abstract The purpose of this experiment was to investigate the welfare of pregnant mares kept in straight stalls and given only limited exercise, conditions that are similar to those encountered in the pregnant mare urine industry. Sixteen pregnant mares (eight in each of two years) were randomly assigned to two groups: Ex (exercised in a paddock for 30 min per day) or NoEx (exercised for one 30 min period every 14 days). The horses were housed in straight (or ‘tie’) stalls for six months and ha
A 7-year-old female Maltese presented for evaluation of severe vomiting. A diagnosis of pylorogastric intussusception was made during ultrasonographic examination. The intussusception spontaneously underwent reduction by the following morning.
The expression of immunogenic markers after differentiation of umbilical cord blood (UCB)-derived mesenchymal stem cells (MSC) has been poorly investigated and requires extensive in vitro and in vivo testing for clinical application. The expression of human leukocyte antigen (HLA) classes on UCB-derived MSC was tested by Fluorescence-activated cell sorting analysis and immunocytochemical staining. The undifferentiated MSC were moderately positive for HLA-ABC, but almost completely negative for H
In a male Korean native calf 14 days of age, polymelia (notomelia) was observed macroscopically and radiographically. External features included two normal forelimbs, two normal hindlimbs and two undeveloped extra forelimbs. The extra forelimbs were attached to the caudal regions of the right scapula and devoid of muscular tissues. In the extra forelimbs, a scapula-like bone formed a joint with the incompletely duplicated humerus. The humerus fused with the incompletely duplicated radius. The ul
A retrospective study was conducted to determine the relative frequency and type of elimination problem seen in dogs at a university referral practice and to evaluate the efficacy of the suggested treatments. Cases presented to the Animal Behavior Clinic at Cornell University between 1987 and 1996 were reviewed. Of 1,173 cases, 105 (9%) were house-soiling cases. Of these cases, the authors obtained outcome information from 70. Within the diagnosis of house soiling, incomplete housebreaking (n=59
Wild migratory birds are key for ecosystem health but highly sensitive to anthropogenic activities. Therefore, wild migratory birds often undergo rehabilitation to prevent species extinction or biodiversity monitoring. However, the impact of rehabilitation on the gut microbiome of wild migratory birds, which is closely associated with host fitness, remains unclear. For the migratory bird species considered natural monuments in South Korea evaluated here, such impacts could include rehabilitation
This bio-acoustic study was aimed at classifying the different porcine wasting diseases through sound analysis with emphasis given to differences in the acoustic footprints of coughs in porcine circo virus type 2 (PCV2), porcine reproductive and respiratory syndrome (PRRS) virus and Mycoplasma hyopneumoniae (MH) -infected pigs from a normal cough. A total of 36 pigs (YorkshireLandraceDuroc) with average weight ranging between 25-30 kg were studied, and blood samples of the suspected infected pig
BACKGROUND: Sarcoptic mange in free-ranging raccoon dogs (Nyctereutes procyonoides) caused by Sarcoptes scabiei is a widespread zoonotic disease that causes severe skin lesions with significant morbidity and mortality. Fluralaner is a member of the isoxazoline chemical class and is an acaricide and insecticide widely used in flea, tick and mite infections of dogs (Canis lupus familiaris). OBJECTIVE: To evaluate the clinical efficacy of orally administered fluralaner in free-ranging raccoon dogs
The aims of this study were to investigate whether upper airway sounds of dogs with laryngeal paralysis and tracheal collapse have distinct sound characteristics, compared with unaffected dogs. The sounds of 5 dogs with laryngeal paralysis and 5 dogs with tracheal collapse were recorded. Honking sound appeared as predominant clinical signs in dogs with tracheal collapse. Laryngeal stridors appeared as predominant clinical signs in dogs with experimentally produced laryngeal paralysis by resectio
A one-year-old, 2.6 kg, spayed female Maltese dog was referred with passage of faeces coming from the vulva, repeated vaginal discharge and vaginitis. Through physical examination, contrast radiograph and vaginoscopic exploration, the dog was diagnosed with rectovaginal fistula which was surgically corrected. After midline perineal incision, the rectovaginal fistula was isolated and transected. The vaginal and rectal defects were closed separately, but dehiscence of the surgical region took plac
The present study evaluated the effects of fluoxetine on decreasing stereotypic behaviors in Asiatic black bears (ABB). Four captive ABB exhibiting stereotypic behaviors were administered fluoxetine (0.25-1 mg/ kg orally every 24 hr) for 91 days. The animals were monitored twice weekly for 213 days (April to October) using a scan sampling method (preadministration, 30 day; administration, 91 days; postadministration, 92 days). Five blood samples were collected from the jugular vein of each bear
Diagnostic coelioscopy, including liver and kidney biopsies, was performed in seven cinereous vultures (Aegypius monachus). A 5-mm endoscopy system was used for examination of coelomic viscera. The endoscopist rated the ease of entry into the coelom and visualisation. Coelioscopic biopsy was performed using a 5-mm biopsy forceps following the diagnostic coelioscopy, and the diagnostic quality of the samples was evaluated. The endoscopic entry and visualisation scores ranged from satisfactory to
OBJECTIVE: The aim of the present study was to provide ophthalmic reference values under normal physiological conditions for Aegypius monachus (cinereous vulture). PROCEDURES: Thirty-two eyes of sixteen adult captive cinereous vultures were used for this study. Tear tests and tonometry in conscious and anesthetized states, neuro-ophthalmic tests, measurement of corneal diameter, slit-lamp biomicroscopy, ophthalmoscopy, and funduscopy were performed. RESULTS: Schirmer tear test (STT) value was 11
Research Areas
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