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Seung Do Lee

Sungkyunkwan University · Medicine

About the Lab

Professor Seung Do Lee's research lab specializes in interventional cardiology and cardiovascular outcomes, with a focus on optimizing percutaneous coronary intervention (PCI) strategies, dual antiplatelet therapy duration, and risk stratification in patients with cardiovascular disease. The lab investigates hemodynamic and anatomical factors influencing diagnostic accuracy—such as fractional flow reserve and aortocoronary height differences—and evaluates long-term clinical outcomes using large-scale electronic health record data. Their work also emphasizes patient-specific risk markers, including renal function and ankle-brachial index, to refine treatment decisions and improve prognostic prediction in complex cardiovascular populations.

percutaneous coronary interventiondual antiplatelet therapyfractional flow reservecardiovascular outcomesrisk stratification

Research Overview

Papers
8
Total Citations
34
Papers (5y)
8
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
8total
2022
2023
2024
2025
Citations per year (5y)
34total
2022202320242025

Selected Papers

8
1
Article|9 citations·2023
Role and Clinical Importance of Progressive Changes in Echocardiographic Parameters in Predicting Outcomes in Patients With Hypertrophic Cardiomyopathy
Kyehwan Kim, Seung Do Lee, Hyo Jin Lee, Hangyul Kim, Hye Ree Kim, Yun Ho Cho, Jeong Yoon Jang, Min Gyu Kang, Jin‐Sin Koh, Seok‐Jae Hwang, Jin‐Yong Hwang, Jeong Rang Park
SJR Q2Journal of Cardiovascular ImagingOA

Changes in echocardiographic parameters extracted from TTE did not assist in predicting clinical outcomes. Cross-sectionally evaluated TTE parameters were superior to changes in TTE parameters between baseline and FU at predicting cardiovascular events.

Cardiology and Cardiovascular MedicineMedicine
2
Article|7 citations·2024
Renal Function-Stratified Comparison of Short- and Long-Term Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention With Third-Generation Drug-Eluting Stents ― Post Hoc Analysis From the HOST-IDEA Randomized Clinical Trial ―
Jung‐Kyu Han, Seung Do Lee, Doyeon Hwang, Sang-Hyeon Park, Jeehoon Kang, Han‐Mo Yang, Kyung Woo Park, Hyun‐Jae Kang, Bon‐Kwon Koo, Jin Man Cho, Jang-Hyun Cho, Duk Won Bang
SJR Q1Circulation JournalOA

BACKGROUND: The optimal duration of dual antiplatelet therapy (DAPT) in patients with chronic kidney disease undergoing percutaneous coronary intervention (PCI), especially with third-generation drug-eluting stents (DES), remains unknown. METHODS AND RESULTS: =0.88) eGFR groups. TLF and major bleeding events showed similar trends. CONCLUSIONS: In patients undergoing PCI with third-generation DES, 3- to 6-month DAPT was comparable to 12-month DAPT for clinical outcomes regardless of renal functio

SurgeryMedicine
3
Article|7 citations·2023
Perioperative adverse cardiac events and mortality after non-cardiac surgery: a multicenter study
Byungjin Choi, Ah Ran Oh, Jungchan Park, Jong‐Hwan Lee, Kwangmo Yang, Dong Yun Lee, Sang Youl Rhee, Sang‐Soo Kang, Seung Do Lee, Sun Hack Lee, Chang‐Won Jeong, Bumhee Park
SJR Q1Korean journal of anesthesiologyOA

BACKGROUND: Perioperative adverse cardiac events (PACE), a composite of myocardial infarction, coronary revascularization, congestive heart failure, arrhythmic attack, acute pulmonary embolism, cardiac arrest, and stroke during 30-day postoperative period, is associated with long-term mortality, but with limited clinical evidence. We compared long-term mortality with PACE using data from nationwide multicenter electronic health records. METHODS: Data from 7 hospitals, converted to Observational

Cardiology and Cardiovascular MedicineMedicine
4
Article|3 citations·2024
Very early vs delayed invasive strategy in high-risk NSTEMI patients without hemodynamic instability: Insight from the KAMIR-NIH
Seung Do Lee, Rock Bum Kim, Chang-Ok Seo, Moojun Kim, Hyo Jin Lee, Hangyul Kim, Hye Ree Kim, Kyehwan Kim, Min Gyu Kang, Jeong Rang Park, Suk Jae Hwang, Jin‐Yong Hwang
SJR Q1PLoS ONEOA

BACKGROUND: High-risk non-ST-elevation myocardial infarction (NSTEMI) patients' optimal timing for percutaneous coronary intervention (PCI) is debated despite the recommendation for early invasive revascularization. This study aimed to compare outcomes of NSTEMI patients without hemodynamic instability undergoing very early invasive strategy (VEIS, ≤ 12 hours) versus delayed invasive strategy (DIS, >12 hours). METHODS: Excluding urgent indications for PCI including initial systolic blood pressur

Cardiology and Cardiovascular MedicineMedicine
5
Article|3 citations·2023
Impact of height difference between coronary ostium and location of intracoronary pressure sensor on fractional flow reserve measurements
Moon-Seung Soh, Hangyul Kim, Min Gyu Kang, Hyo Jin Lee, Seung Do Lee, Seok‐Jae Hwang, Jin‐Yong Hwang, Kyehwan Kim, Jeong-Rang Park, Hye-Ree Kim, Seung‐Jea Tahk, Myeong‐Ho Yoon
SJR Q1PLoS ONEOA

BACKGROUND: During fractional flow reserve (FFR) measurements, distal coronary pressure (Pd) can be influenced by hydrostatic pressure changes resulting from the height difference (HD) between the coronary ostium and the location of the distal pressure sensor. AIMS: We investigated the effect of aortocoronary HD on the FFR measurements in each coronary artery. METHODS: In this retrospective cohort study, we analyzed 257 patients who underwent FFR measurements and coronary computed tomography (CC

SurgeryMedicine
6
Article|3 citations·2023
Influence of an abnormal ankle-brachial index on ischemic and bleeding events in patients undergoing percutaneous coronary intervention
Hangyul Kim, Seung Do Lee, Hyo Jin Lee, Hye Ree Kim, Kyehwan Kim, Jin‐Sin Koh, Seok‐Jae Hwang, Jin‐Yong Hwang, Jong‐Hwa Ahn, Yongwhi Park, Young‐Hoon Jeong, Jeong Rang Park
SJR Q2The Korean Journal of Internal MedicineOA

BACKGROUND/AIMS: Bleeding events after percutaneous coronary intervention (PCI) have important prognostic implications. Data on the influence of an abnormal ankle-brachial index (ABI) on both ischemic and bleeding events in patients undergoing PCI are limited. METHODS: We included patients who underwent PCI with available ABI data (abnormal ABI, ≤ 0.9 or > 1.4). The primary endpoint was the composite of all-cause death, myocardial infarction (MI), stroke, and major bleeding. RESULTS: Among 4,747

SurgeryMedicine
7
Article|1 citations·2025
Renal function-dependent risk of early invasive strategy in patients with non-ST-segment elevation myocardial infarction: insight from KAMIR-NIH and KRAMI-RCC
Jin Sin Koh, Chang-Ok Seo, Hyo Jin Lee, Moojun Kim, Seung Do Lee, Yong-Lee Kim, Hyoun-Woo Noh, Rock Bum Kim, Hangyul Kim, Hye Ree Kim, Min Gyu Kang, Kyehwan Kim
SJR Q3Heart and Vessels
NephrologyMedicine
8
Article|1 citations·2022
Development of dilated cardiomyopathy with a long latent period followed by viral fulminant myocarditis: A case report
Seung Do Lee, Hyo Jin Lee, Hye Ree Kim, Min Gyu Kang, Kyehwan Kim, Jeong Rang Park
World Journal of Clinical CasesOA

BACKGROUND: The clinical course of acute myocarditis ranges from the occurrence of a few symptoms to the development of fatal fulminant myocarditis. Specifically, fulminant myocarditis causes clinical deterioration very rapidly and aggressively. The long-term prognosis of myocarditis is varied, and it fully recovers without leaving any special complications. However, even after recovery, heart failure may occur and eventually progress to dilated cardiomyopathy (DCM), which causes serious left ve

Cardiology and Cardiovascular MedicineMedicine

Research Areas

Cardiology and Cardiovascular MedicineSurgeryNephrology

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