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Seung Ho Choi

Yonsei University · Medicine

About the Lab

Professor Seung Ho Choi's research lab specializes in surgical oncology and minimally invasive surgical techniques, with a focus on improving outcomes in gastrointestinal malignancies such as gastric and colorectal cancer. The lab investigates innovative surgical protocols, including fast-track surgery and lymph node dissection (RAG with lymphadenectomy), to enhance postoperative recovery and patient safety. Additional research interests include the biological mechanisms of tumor progression, particularly the role of cell adhesion molecules like CD44 in cancer metastasis, and rare surgical conditions such as auricular pseudocysts. The lab also explores biophysical phenomena, such as optical precursor formation in transparent media, reflecting a multidisciplinary approach to surgical science and biomedical physics.

surgical oncologyminimally invasive surgerygastric cancerCD44fast-track surgery

Research Overview

Papers
451
Total Citations
8,161
Papers (5y)
21
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
21total
2021
2022
2023
2024
2025
Citations per year (5y)
231total
20212022202320242025

Selected Papers

15
1
Article|287 citations·2009
Robot-Assisted Gastrectomy With Lymph Node Dissection for Gastric Cancer
Jyewon Song, Sung Jin Oh, Wook Ho Kang, Woo Jin Hyung, Seung Ho Choi, Sung Hoon Noh
SJR Q1Annals of SurgeryOA

This study demonstrated that RAG with lymphadenectomy can be applied safely and effectively for patients with gastric cancer.

Pulmonary and Respiratory MedicineMedicine
2
Article|139 citations·2012
Safety and Efficacy of Fast‐track Surgery in Laparoscopic Distal Gastrectomy for Gastric Cancer: A Randomized Clinical Trial
Jong Won Kim, Whan Sik Kim, Jae‐Ho Cheong, Woo Jin Hyung, Seung Ho Choi, Sung Hoon Noh
SJR Q1World Journal of Surgery

BACKGROUND: Fast-track surgery has been shown to enhance postoperative recovery in several surgical fields. This study aimed to evaluate the safety and efficacy of fast-track surgery in laparoscopic distal gastrectomy. METHODS: The present study was designed as a single-center, randomized, unblinded, parallel-group trial. Patients were eligible if they had gastric cancer for which laparoscopic distal gastrectomy was indicated. The fast-track surgery protocol included intensive preoperative educa

SurgeryMedicine
3
Article|104 citations·2011
Relationships between serum total bilirubin levels and metabolic syndrome in Korean adults
Seung Ho Choi, K. E. Yun, Hee Jeong Choi
SJR Q1Nutrition Metabolism and Cardiovascular Diseases
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
Article|73 citations·1984
Endochondral Pseudocyst of the Auricle in Chinese
Seung Ho Choi, King Hei Stanley Lam, Kuang‐Yang Chan, F. N. Ghadially, Anderson Ng
Archives of Otolaryngology - Head and Neck Surgery

Thirty-one patients with endochondral pseudocysts of the auricle were seen over a four-year period in the Department of Surgery at the University of Hong Kong. The lesions chiefly affected Chinese males (90.3%); 80.6% involved the scaphoid fossa on the anterior surface of the pinna. They were usually asymptomatic and static in size. Excision of the anterior wall, followed by contour pressure dressing, gave cosmetically satisfactory results in 90% of the patients, and there were no recurrences. P

GeneticsBiochemistry, Genetics and Molecular Biology
5
Article|66 citations·2004
Observation of Optical Precursors in Water
Seung Ho Choi, Ulf L. Österberg
SJR Q1Physical Review Letters

We observe the formation of optical precursors while propagating 540 fs pulses through 700 mm of deionized water. The launched pulses were strongly chirped to give them a bandwidth of approximately 60 nm to more readily excite the precursors. The precursors attenuated nonexponentially with distance.

Atomic and Molecular Physics, and OpticsPhysics and Astronomy
6
Article|54 citations·2000
CD44s expression in human colon carcinomas influences growth of liver metastases
Seung Ho Choi, Kazuhisa Takahashi, Hiroshi Eto, Sam S. Yoon, Kenneth K. Tanabe
SJR Q1International Journal of CancerOA

CD44 is a family of cell-surface adhesion molecules which exist in several isoforms arising from mRNA alternative. Malignant transformation of colonic mucosa is associated with alterations in CD44 expression, which result in up-regulation of high-molecular-weight CD44 isoforms and down-regulation of CD44s. We have demonstrated that stable transfection of CD44s into colon-carcinoma cell lines reduces their tumorigenicity. To understand the influence of CD44s expression on the metastatic potential

Cell BiologyBiochemistry, Genetics and Molecular Biology
7
Review|36 citations·2010
Surgical management of the esophageal leiomyoma: lessons from a retrospective review
Seung Ho Choi, Young Tae Kim, Kook Nam Han, Y. J., Chang Hyun Kang, Sook Whan Sung, J. H. Kim
SJR Q1Diseases of the EsophagusOA

Esophageal leiomyoma is the most common benign tumor of the esophagus. Although enucleation via thoracotomy has been considered standard treatment, minimally invasive surgery is increasingly used for the treatment of this disease. We analyzed our surgical outcomes by comparing thoracotomy and the thoracoscopic approach. A retrospective review was performed of patients who underwent surgical resection of esophageal leiomyomas at the Seoul National University Hospital. Between 1982 and 2005, 63 pa

GastroenterologyMedicine
8
Review|29 citations·2019
The clinical efficacy of stem cell therapy for complex perianal fistulas: a meta-analysis
Seung Ho Choi, Byeong Geon Jeon, Gibong Chae, Sang-Jeon Lee
SJR Q1Techniques in Coloproctology
SurgeryMedicine
9
Article|26 citations·2015
Nationwide Survey on Bariatric and Metabolic Surgery in Korea: 2003–2013 Results
Hyuk-Joon Lee, Hye Seong Ahn, Youn Baik Choi, Sang-Moon Han, Sang‐Uk Han, Yoonseok Heo, Kyoung Yul Hur, Eung Kook Kim, Wook‐Hwan Kim, Young-Jin Kim, Han Hong Lee, Joo Ho Lee
SJR Q1Obesity SurgeryOA

A survey to evaluate the current status of bariatric and metabolic operations in Korea was conducted. Data from 5467 cases (32 hospitals) were collected. The annual numbers of bariatric and metabolic operations increased each year, from 139 in 2003 to 1686 in 2013. Adjustable gastric band (AGB, 67.2 %) was the most common operation, followed by sleeve gastrectomy (SG, 14.2 %), and Roux-en-Y gastric bypass (RYGB, 12.7 %). Mean patient age and body mass index (BMI) were 35.4 years and 35.9 kg/m2,

SurgeryMedicine
10
Article|24 citations·1996
Laparoscopy-assisted radical subtotal gastrectomy for early gastric carcinoma.
Seung Ho Choi, Dong Sup Yoon, Hoon Sang Chi, Jin Sik Min
SJR Q2Yonsei Medical JournalOA

In order to evaluate whether it is possible to perform a minimal invasive operation without compromising to the radicality, we analyzed six patients who had been performed laparoscopy-assisted radical subtotal gastrectomy at Yongdong Severance Hospital, Yonsei University College of Medicine between September 1995 and February 1996. All patients were diagnosed as early gastric carcinoma without lymph node metastases preoperatively by upper gastrointestinal barium study (UGI), esophagogastroduoden

Pulmonary and Respiratory MedicineMedicine
11
Article|22 citations·2019
Multicenter results of long-limb bypass reconstruction after gastrectomy in patients with gastric cancer and type II diabetes
Jong-Han Kim, Yeon‐Ju Huh, Susan Park, Young Suk Park, Do Joong Park, Jin‐Won Kwon, Joo Ho Lee, Yoon Seok Heo, Seung Ho Choi
SJR Q2Asian Journal of SurgeryOA

Roux-en-Y bypass with increased length of limbs after gastrectomy shows a favorable glycemic control for gastric cancer patients with type II diabetes without nutritional deficit and anemia. To obtain future perspectives, large-scale prospective studies with long-term outcomes are needed.

SurgeryMedicine
12
Article|19 citations·2010
Long-term, antidiabetogenic effects of GLP-1 gene therapy using a double-stranded, adeno-associated viral vector
Seung Ho Choi, H C Lee
SJR Q1Gene TherapyOA
SurgeryMedicine
13
Article|13 citations·2008
Comparison of Remifentanil and Fentanyl for Postoperative Pain Control after Abdominal Hysterectomy
최승호, 구본녀, 남순호, 이성진, 김기준, 길혜금, 이기영, 전동혁
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120080490020204

Purpose: In this randomized, double-blind study, we investigated the analgesic efficacy and side effects of continuous constant-dose infusions of remifentanil after total abdominal hysterectomy and compared it to fentanyl. Materials and Methods: Fifty-six adult female patients scheduled for elective total abdominal hysterectomy were enrolled in this study. Patients were randomly assigned to two groups according to fentanyl (group F, n=28) or remifentanil (group R, n=28) for postoperative analges

14
Article|10 citations·2000
Effects of Polycomb Group Mutations on the Expression of Ultrabithorax in the Drosophila Visceral Mesoderm
Seung Ho Choi, Chun Taek Oh, Sang Hee Kim, Yun-Taik Kim, Sang‐Hak Jeon
SJR Q1Molecules and Cells
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Review|10 citations·2024
Enhanced Recovery After Surgery for Craniotomies: A Systematic Review and Meta-analysis
Seung Hyun Kim, Seung Ho Choi, Jisu Moon, H. Kim, Yong Seon Choi
SJR Q2Journal of Neurosurgical Anesthesiology

The efficacy of the enhanced recovery after surgery (ERAS) protocols in neurosurgery has not yet been established. We performed a systematic review and meta-analysis of randomized controlled trials to compare the effects of ERAS protocols and conventional perioperative care on postoperative outcomes in patients undergoing craniotomy. The primary outcome was postoperative length of hospital stay. Secondary outcomes included postoperative pain visual analog pain scores, incidence of postoperative

SurgeryMedicine

Research Areas

Pulmonary and Respiratory MedicineAerospace EngineeringSurgeryMolecular BiologyGastroenterologyOtorhinolaryngology

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