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Seung Hwan Song

Hanyang University · Medicine

About the Lab

Professor Seung Hwan Song's research lab focuses on translational and clinical research in autoimmune diseases, critical care medicine, and pediatric and adult surgical outcomes. The lab investigates immune dysregulation in systemic lupus erythematosus, particularly the role of adipokines like leptin and regulatory T cells, while also exploring advanced life support strategies such as VV-ECMO in post-cardiac surgery ARDS. Additionally, the lab examines long-term outcomes in kidney transplantation and innovative pain management techniques in spinal and chest wall surgery, including cryoanalgesia in minimally invasive pectus excavatum repair. The integration of novel imaging techniques, such as 3D body surface scanning, for musculoskeletal deformities like pectus carinatum further highlights the lab’s commitment to improving diagnostic accuracy and treatment efficacy in pediatric and adult populations.

systemic lupus erythematosusVV-ECMOkidney transplantationpostoperative pain management3D body scanning

Research Overview

Papers
31
Total Citations
214
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2020
2021
2022
2023
2024
Citations per year (5y)
92total
20202021202220232024

Selected Papers

15
1
Article|45 citations·2017
Leptin levels in patients with systemic lupus erythematosus inversely correlate with regulatory T cell frequency
X Wang, Yushan Qiao, Yang Li, Seung Hwan Song, Yuxiang Han, Yu-Dan Tian, Meng Ding, Hongtao Jin, Fang Shao, Aijiang Liu
SJR Q2Lupus

Leptin levels are increased in patients with systemic lupus erythematosus (SLE) but little is known on how this correlates with several disease characteristics including the frequency of regulatory T cells (Tregs). Here we compared serum leptin levels with frequency of circulating Tregs in 47 lupus patients vs. 25 healthy matched controls. Correlations with lupus disease activity were also analyzed, as well as Treg proliferation potential. It was found that leptin was remarkably increased in SLE

Endocrine and Autonomic SystemsNeuroscience
2
Article|20 citations·2016
Outcome of veno-venous extracorporeal membrane oxygenation use in acute respiratory distress syndrome after cardiac surgery with cardiopulmonary bypass
Joo Han Song, Wongi Woo, Seung Hwan Song, Hyo Hyun Kim, Bong‐Joon Kim, Ha Eun Kim, Do Jung Kim, Jee Won Suh, Yu Rim Shin, Han Ki Park, Seung Hyun Lee, Hyun‐Chel Joo
SJR Q2Journal of Thoracic DiseaseOA

VV-ECMO support can be a feasible rescue strategy for adult patients who develop refractory ARDS after a cardiac surgery. Additionally, the RESP score seems a valuable prognostic tool for post-ECMO survival outcome in this patient population as well.

Biomedical EngineeringEngineering
3
Article|17 citations·2022
Limited cryoablation reduces hospital stay and opioid consumption compared to thoracic epidural analgesia after minimally invasive repair of pectus excavatum
Seung Hwan Song, Duk Hwan Moon, Yon Hee Shim, Hyun‐Joo Jung, Sungsoo Lee
SJR Q3MedicineOA

pain following minimally invasive repair of pectus excavatum (MIRPE) is a critical concern that leads to a prolonged hospital stay and high doses of opiates administered to the patients. This study aimed to evaluate the efficacy of intraoperative cryoanalgesia (cryoablation of the intercostal nerves) during MIRPE. We retrospectively analyzed the data of 64 patients who underwent MIRPE and received cryoanalgesia or epidural analgesia between January 2019 and January 2021. The oral morphine millig

SurgeryMedicine
4
Article|17 citations·2022
Effect of pretransplant dialysis vintage on clinical outcomes in deceased donor kidney transplant
Jeong‐Hoon Lim, Yena Jeon, Deok Gie Kim, Yeong Hoon Kim, Joong Kyung Kim, Jaeseok Yang, Myoung Soo Kim, Hee‐Yeon Jung, Ji‐Young Choi, Sun-Hee Park, Chan‐Duck Kim, Yong-Lim Kim
SJR Q1Scientific ReportsOA

The waiting time for deceased donor kidney transplants (DDKT) is increasing. We evaluated DDKT prognosis according to the pretransplant dialysis vintage. A total of 4117 first-time kidney transplant recipients were enrolled from a prospective nationwide cohort in Korea. DDKT recipients were divided into tertiles according to pretransplant dialysis duration. Graft failure, mortality, and composite were compared between DDKT and living donor kidney transplant (LDKT) recipients. Pretransplant dialy

TransplantationMedicine
5
Article|16 citations·2020
The role of postoperative radiotherapy in stage II and III thymoma: a Korean multicenter database study
Seung Hwan Song, Jee Won Suh, Woo Sik Yu, Go Eun Byun, Sung Yong Park, Chang Young Lee, Dae Joon Kim, Hyo Chae Paik, Kyung Soo Chung, Geun Dong Lee, Sehoon Choi, Hyeong Ryul Kim
SJR Q2Journal of Thoracic DiseaseOA

PORT improved the RFS and OS in stage III thymoma patients, but showed no survival benefit in stage II patients.

NeurologyMedicine
6
Article|16 citations·2019
Effect of Sarcopenic Overweight on Lung Transplant Based in Three-Dimensional Reconstructed Psoas Muscle Mass
Jee Won Suh, Hyo Chae Paik, Woo Sik Yu, Seung Hwan Song, Moo Suk Park, Song Yee Kim, Jin Gu Lee
SJR Q1The Annals of Thoracic SurgeryOA
SurgeryMedicine
7
Article|11 citations·2020
Usefulness of 3-Dimensional Body Surface Scanning in the Evaluation of Patients with Pectus Carinatum
Seung Hwan Song, Chong Hoon Kim, Duk Hwan Moon, Sungsoo Lee
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Background: Radiographic modalities have been commonly used to evaluate pectus carinatum (PC), and compressive orthotic bracing is the most widely accepted treatment method. The aim of this study was to determine the efficacy of 3-dimensional (3D) body surface scanning as an alternative modality for the evaluation of PC. \n\nMethods: The medical records of 63 patients with PC who were treated with compressive orthotic bracing therapy between July 2017 and February 2019 were retrospectively analy

SurgeryMedicine
8
Article|10 citations·2022
Prognosis of Spontaneous Pneumothorax/Pneumomediastinum in Coronavirus Disease 2019: The CoBiF Score
Wongi Woo, Vincent Kipkorir, Adina Maria Marza, Shadi Hamouri, Omar Albawaih, Arkadeep Dhali, Woo-Shik Kim, Zarir Udwadia, Abdulqadir J. Nashwan, Nissar Shaikh, Alessandro Belletti, Giovanni Landoni
SJR Q1Journal of Clinical MedicineOA

Objectives: Pneumothorax and pneumomediastinum are associated with high mortality in invasively ventilated coronavirus disease 2019 (COVID-19) patients; however, the mortality rates among non-intubated patients remain unknown. We aimed to analyze the clinical features of COVID-19-associated pneumothorax/pneumomediastinum in non-intubated patients and identify risk factors for mortality. Methods: We searched PubMed Scopus and Embase from January 2020 to December 2021. We performed a pooled analys

Pulmonary and Respiratory MedicineMedicine
9
Article|10 citations·2018
Successful Surgical Treatment of a Recurrent Esophageal Malignant Gastrointestinal Neuroectodermal Tumor
Seung Hwan Song, Jung-Hoon Shin, Hyang Joo Ryu, Dae Joon Kim, Sung Yong Park
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Malignant gastrointestinal neuroectodermal tumor (GNET) is a very rare disease entity, especially in the esophagus. The diagnosis of GNET is based on histologic, immunohistochemical, and genetic findings. The choice of treatment is complete resection, and further treatment options can be considered. Herein, we describe a case of successful surgical treatment of a 23-year-old man with recurrent malignant esophageal GNET.

NeurologyMedicine
10
Review|7 citations·2024
Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis
Wongi Woo, Du–Young Kang, Yoon Jin, Vincent Kipkorir, Seung Hwan Song, Duk Hwan Moon, Jae Il Shin, Sungsoo Lee
SJR Q2Journal of Thoracic DiseaseOA

The portion of IA in cases of pure GGN is significantly larger that expected. More than half of them owned invasiveness components if MIA and IA were combined. Furthermore, there were quite number of lesions with aggressive histologic patterns other than the lepidic subtype. Therefore, further attempts are necessary to differentiate advanced histologic subtype among radiologically favorable pure GGN.

Pulmonary and Respiratory MedicineMedicine
11
Article|7 citations·2019
The lung allocation score could evaluate allocation systems in countries that do not use the score
Woo Sik Yu, Jee Won Suh, Seung Hwan Song, Hyo Chae Paik, Song Yee Kim, Moo Suk Park, Jin Gu Lee
SJR Q1PLoS ONEOA

The LAS demonstrated the characteristics of LTx recipients in Korea and the Korean allocation system needs to be revised to reduce the number of patients receiving LTx in Status 0. The LAS system could be used as a tool to evaluate lung allocation systems in countries that do not use the LAS system.

SurgeryMedicine
12
Article|6 citations·2019
Neoadjuvant therapy for thymic neoplasms reduces tumor volume per 3D-reconstructed images but does not improve the complete resection rate
Jee Won Suh, Sung Yong Park, Chang Young Lee, Seung Hwan Song, Dae Joon Kim, Hyo Chae Paik, Kyoung Young Chung, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho, Jin Gu Lee
SJR Q1PLoS ONEOA

Neoadjuvant therapy does not significantly influence the R0 resection rate or overall survival relative to primary surgery. Nevertheless, it may by useful for patients planning surgical resection because it significantly reduces the presurgical tumor volume and extent of invasion.

NeurologyMedicine
13
Article|6 citations·2022
Dominant predictors of early post-transplant outcomes based on the Korean Organ Transplantation Registry (KOTRY)
Jong Cheol Jeong, Tai Yeon Koo, Han Ro, Dong Ryeol Lee, Dong Won Lee, Jieun Oh, Jayoun Kim, Dong‐Wan Chae, Young Hoon Kim, Kyu Ha Huh, Jae Berm Park, Yeong Hoon Kim
SJR Q1Scientific ReportsOA

Data for Asian kidney transplants are very limited. We investigated the relative importance of prognostic markers in Asian kidney transplants by using Korean Organ Transplantation Registry (KOTRY) cohort. Prediction models were developed by data-driven variable selection approach. The relative importance of the selected predictors was measured by dominance analysis. A total of 4854 kidney transplant donor-recipient pairs were analyzed. Overall patient survival rates were 99.8%, 98.8%, and 91.8%

TransplantationMedicine
14
Article|6 citations·2017
Surgical Repair of a Traumatic Tracheobronchial Injury in a Pediatric Patient Assisted with Venoarterial Extracorporeal Membrane Oxygenation
Jee Won Suh, Hong Ju Shin, Chang Young Lee, Seung Hwan Song, Kyoung Sik Narm, Jin Gu Lee
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Tracheobronchial rupture due to blunt chest trauma is a rare but life-threatening injury in the pediatric population. Computed tomography (CT) is not always reliable in the management of these patients. An additional concern is that ventilation may be disrupted during surgical repair of these injuries. This report presents the case of a 4 -year-old boy with an injury to the lower trachea and carina due to blunt force trauma that was missed on the initial CT scan. During surgery, he was administe

SurgeryMedicine
15
Article|5 citations·2018
Risk factors associated with postoperative prosthetic graft patency in Leriche syndrome
Miju Bae, Sung Woon Chung, Chung Won Lee, Up Huh, Min Su Kim, Seung Hwan Song
SJR Q2Asian Journal of SurgeryOA

For better graft patency after an open surgical repair of Leriche syndrome, strict postoperative hypertension control and distal run-off resolution are necessary.

SurgeryMedicine

Research Areas

SurgeryPulmonary and Respiratory MedicineTransplantationNeurologyEndocrine and Autonomic SystemsBiomedical Engineering

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