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Seung-ju Yoon

Korea University · Medicine

About the Lab

Professor Seung-ju Yoon's research lab specializes in anesthesiology and critical care medicine, focusing on the hemodynamic and metabolic responses during general anesthesia. The lab investigates anesthetic depth monitoring using advanced neuromonitoring tools such as the bispectral index (BIS) and entropy, aiming to optimize patient safety during surgery. Key research directions include the management of complications like malignant hyperthermia, propofol-induced lactic acidosis, and pain associated with intravenous anesthetic administration. The lab also explores hemodynamic stability during airway management using agents like remifentanil and esmolol, particularly in the context of rapid-sequence induction and critical care support.

anesthetic depth monitoringmalignant hyperthermiapropofol-induced lactic acidosishemodynamic stabilityremifentanil

Research Overview

Papers
20
Total Citations
41
Papers (5y)
6
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
6total
2014
2016
2017
2018
2019
Citations per year (5y)
29total
20142016201720182019

Selected Papers

15
1
Article|23 citations·2016
A prospective randomized comparative study of postoperative pain control using an epidural catheter in patients undergoing posterior lumbar interbody fusion
Si-Young Park, Howard S. An, Soon Hyuck Lee, Seung Woo Suh, Jeong Lae Kim, Seung Joo Yoon
SJR Q1European Spine Journal
SurgeryMedicine
2
Article|5 citations·2001
A Statistical Analysis of the Causes of Cancellation of Elective Operation
Seung Joo Yoon, Keum Ok Choi, Suk Min Yoon, Hae Ja Lim, Hye Won Lee, Hun Cho, Seong Ho Chang
SJR Q1Korean Journal of Anesthesiology
Safety, Risk, Reliability and QualityEngineering
3
Article|3 citations·2014
Propofol Infusion Associated Metabolic Acidosis in Patients Undergoing Neurosurgical Anesthesia : A Retrospective Study
최윤지, Min Chul Kim, 임영진, 윤승주, 윤석민, Hei-Ryeo Yoon

Objective : Propofol and volatile anesthesia have been associated with metabolic acidosis induced by increased lactate. This study was designed to evaluate changes in pH, base excess (BE), and lactate in response to different anesthetic agents and to characterize propofol infusion-associated lactic acidosis. Methods : The medical records of patients undergoing neurosurgical anesthesia between January 2005 and September 2012 were examined. Patients were divided into 2 groups : those who received

4
Article|3 citations·2017
Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest -a case report-
허협, 윤승주, 정재승, 박상재, 박민경, 임춘학

Malignant hyperthermia (MH) may lead to metabolic crisis of skeletal muscle in susceptible individuals following exposure to triggering agents such as volatile anesthetics or depolarizing muscle relaxants. MH is a rare and a potentially lethal disease, which can lead to cardiac arrest. We report a case of severe MH, in which the rapidly evolving signs of hypermetabolism eventually resulted in cardiac arrest. Despite conventional treatments following cardiopulmonary resuscitation, the patient’s v

5
Article|2 citations·2004
The Differences in Bispectral Index according to Age during Sevoflurane Anesthesia in Children Aged 1-7 Years
Ah Young Oh, Nam Su Gil, Seung Joo Yoon, Hee Soo Kim, Seong Deok Kim, Chong Sung Kim
SJR Q1Korean Journal of AnesthesiologyOA

Bispectral index (BIS) . Fourier (bispectral) (isoelectric EEG) 0, 100 . 1,2) BIS 40-65, (sedation) BIS 65-85 . 3) BIS . 1971 BIS 4) BIS . 1-7 sevoflurane

Anesthesiology and Pain MedicineMedicine
6
Article|2 citations·2012
Single pretreatment of remifentanil may reduce pain after propofol and rocuronium injection in rapid sequence induction
최윤지, 박한석, 이한, 윤승주

Background: We designed this double-blind, placebo-controlled study to compare the efficacy of remifentanil in reducing the pain of both propofol and rocuronium injection during rapid-sequence induction. Methods: Ninety-five patients, scheduled for elective surgery under general anesthesia, were divided into 3 groups:saline (Group S, n = 31), remifentanil 1 μg/kg (Group R, n = 32), and lidocaine 1.5 mg/kg (Group L, n = 32) were administered after tourniquet application. The occlusion was release

7
Article|1 citations·2005
The Optimal Depth of Central Venous Catheter by Using Transesophageal Echocardiography for Pediatric Patients
Teo Jeon Shin, Seung Joo Yoon, Chongdoo Park, Chong Sung Kim, Seong Deok Kim
SJR Q1Korean Journal of AnesthesiologyOA

Background: Incorrect positioning of central venous catheter leads to serious complications. To prevent these complications, catheter tip should be at the superior vena cava and right atrial junction.

Emergency Medical ServicesHealth Professions
8
Article|1 citations·2010
Effect of remifentanil or esmolol on bispectral index and entropy to tracheal intubation during propofol anesthesia
최윤지, 신혜원, 김연희, 최성욱, 박지용, 윤승주, 장성호

Background:The bispectral index (BIS) and entropy (response entropy, state entropy; RE, SE) have been used to monitor the anesthetic depth, and the difference between RE and SE (RE-SE difference) may represent the nociceptive stimuli during general anesthesia. This study was designed to determine whether BIS or entropy (RE, SE, and RE-SE difference) represent the response to tracheal intubation with iv bolus of remifentanil or esmolol for stable hemodynamic control during propofol anesthesia. Me

9
Article|1 citations·2010
Posterior auricular pain caused by the trigger points in the sternocleidomastoid muscle aggravated by psychological factors -A case report-
민삼홍, 장성호, 전세근, 윤승주, 박지용, 신혜원

Psychological factors play a significant role in the pain mechanism, and psychological approaches may be useful complements to traditional medical and surgical treatments in pain management. The authors report a case of recurrent severe posterior auricular pain caused by trigger points in the right sternocleidomastoid muscle and influenced by stressful psychological situations (e.g., family affairs, job loss) in a 50-year-old man.

10
Article|0 citations·2004
Anaesthetic Management of an Adult with a Modified Fontan Procedure in Noncardiac Surgery: A case report
Seung Joo Yoon, Yun Suk Choe, Ah Young Oh, Hee Soo Kim, Seong Deok Kim, Chong Sung Kim
SJR Q1Korean Journal of AnesthesiologyOA

선천성심질환의 진단과 치료의 발전으로 선천성심질환을 가진 환자들 중 사춘기 및 성인에 이르기까지 생존하는 비 율이 증가하고 있다. 1) 최초의 수술로 심장 기형을 완전히 교정 받은 환자는 증상 없이 정상적인 심혈관계 소견을 보 이나 고식적수술이나 부분적교정술을 시행

EpidemiologyMedicine
11
Article|0 citations·2000
Does Perioperative Monitoring of the Train-of-Four Response Influence the Frequency of Postoperative Residual Curarization in Propofol Anesthesia?
Seung Joo Yoon, Moon Seok Chang, Hun Cho, Myoung Hoon Kong, Suk Min Yoon
SJR Q1Korean Journal of AnesthesiologyOA

Background : Sometimes hypoxemia occurs in the postoperative recovery room because of post- operative residual curarization (PORC). Some reports show that postoperative residual curarization is common. FORC occurs after the use of the long-acting muscle relaxants. It has been recommended to use intermediate-acting muscle relaxants and a TOF monitor to decrease PORC. The purpose of this study was to examine whether the use of the TOF monitor during propofol anesthesia affects the incidence of pos

Anesthesiology and Pain MedicineMedicine
12
Article|0 citations·2018
Dantrolene treatment in a patient with uncontrolled hyperthemia after general anesthesia: a case report of suspected malignant hyperthermia - A case report -
고경희, 박민경, 최성욱, 허협, 윤승주, 임춘학
https://doi.org/10.17085/apm.2018.13.2.176

Fever (body temperature above 38°C) is relatively common during the first few days after general anesthesia. Postoperative fever is usually caused by the inflammation induced by surgery and resolves spontaneously; however, it can be a manifestation of a serious complication such as malignant hyperthermia. We report a case of postoperative hyperthermia (body temperature > 40°C) that was refractory to conventional anti-pyretic measures and finally resolved with dantrolene administration.

13
Article|0 citations·2011
Postoperative renal function in patients is unaltered after robotic-assisted radical prostatectomy
안재현, 임춘학, Hye In Chung, 최성욱, 윤승주, 임혜자

Background: Pneumoperitoneum with an intra-abdominal pressure (IAP) of 14 mmHg is known to decrease renal function. Robotic-assisted radical prostatectomy (RARP) requires an IAP of more than 15 mmHg for operation. Therefore, we retrospectively investigated whether patients who underwent RARP experienced renal insufficiency during the postoperative period (at postoperative days 7 and 30). Methods: One hundred patients who underwent RARP were enrolled in this study. Preoperative serum blood urea n

14
Article|0 citations·2013
한국 보건의료 분야 공적개발원조에 대한 실증분석: 보건 의료 수요에 적합하게 이루어지고 있는가?
윤승주, 윤지웅
대한의사협회지

This paper aims to examine the factors that affect the amount of official development assistance (ODA) a developing country receives for healthcare by the Korean government. We empirically tested to what extent the amount of Korea’s ODA in health care services, infrastructure,HIV/AIDS, and tuberculosis are affected by the relevant demand factors in the recipient countries. To do so, we carried out country-level multivariate regression analyses by setting the amount of ODA for four health care se

15
Article|0 citations·2009
Occurrence of iatrogenic pneumothorax during laparoscopy-assisted distal gastrectomy
김연희, 윤승주, 임춘학, 박지용, 이혜원

The occurrence of a pneumothorax during laparoscopy-assisted distal gastrectomy (LADG) is rare. A pneumothorax was developed during a LADG under general anesthesia in a 67-year-old woman with gastric cancer. About 140 minutes after CO2 insufflation, sudden hemodynamic collapse occurred. A defect was noted in the diaphragm. After immediate repair under laparoscopy, hemodynamic stability was achieved within several minutes. In the anesthetic management of a LADG, the anesthesia provider should be

Research Areas

Anesthesiology and Pain MedicineSurgerySafety, Risk, Reliability and QualityEmergency Medical ServicesEpidemiology

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