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Seung-pil Jeong

Korea University · Medicine

About the Lab

Professor Seung-pil Jeong's research lab focuses on translational oncology, with a primary emphasis on understanding the molecular mechanisms underlying aggressive cancer behaviors and improving prognostic prediction in various malignancies. The lab investigates key factors such as tumor metastasis, lymph node involvement, and epigenetic alterations—particularly CDH1 gene hypermethylation—in breast, thyroid, and lymphoid cancers. Their work also explores the impact of treatment modalities like neoadjuvant chemotherapy on pathological outcomes and long-term survival, aiming to refine risk stratification and guide personalized therapeutic strategies.

cancer metastasislymph node ratioepigenetic alterationthyroid cancerbreast cancer

Research Overview

Papers
185
Total Citations
1,852
Papers (5y)
64
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
64total
2021
2022
2023
2024
2025
Citations per year (5y)
275total
20212022202320242025

Selected Papers

15
1
Article|41 citations·2011
Comparison between screen-detected and symptomatic breast cancers according to molecular subtypes
Jiyoung Kim, Se-Kyung Lee, SooYoun Bae, Min-Young Choi, Jeonghui Lee, Seung Pil Jung, Sangmin Kim, Jun-Ho Choe, Jung‐Han Kim, Jee Soo Kim, Jeong Eon Lee, Seok Jin Nam
SJR Q1Breast Cancer Research and Treatment
Cancer ResearchBiochemistry, Genetics and Molecular Biology
2
Article|41 citations·2020
Clinical Experience with Treatment of Aquafilling Filler-Associated Complications: A Retrospective Study of 146 Cases
Sik Namgoong, Hong Kyu Kim, Yong-Jae Hwang, Seung Ho Shin, Hi‐Jin You, Deok‐Woo Kim, Aeree Kim, Seung Pil Jung, Eul‐Sik Yoon
SJR Q1Aesthetic Plastic Surgery
DermatologyMedicine
3
Article|38 citations·2018
Clinical subtypes and prognosis of pregnancy-associated breast cancer: results from the Korean Breast Cancer Society Registry database
Soo Youn Bae, Sei Joong Kim, Jung Sun Lee, Eun Sook Lee, Eun‐Kyu Kim, Ho Young Park, Young Jin Suh, Hong Kyu Kim, Ji Young You, Seung Pil Jung
SJR Q1Breast Cancer Research and Treatment
OncologyMedicine
4
Article|38 citations·2012
Invasive Pleomorphic Lobular Carcinoma of the Breast: Clinicopathologic Characteristics and Prognosis Compared with Invasive Ductal Carcinoma
Seung Pil Jung, Se Kyoung Lee, Sangmin Kim, Min-Young Choi, Soo Youn Bae, Jiyoung Kim, Minkuk Kim, Won Ho Kil, Eun Yoon Cho, Jun-Ho Choe, Jung‐Han Kim, Jee Soo Kim
SJR Q2Journal of Breast CancerOA

Our data suggest that patients with IPLC present with poor prognostic factors such as large tumor size, poor histologic grade and advanced stage at diagnosis. These aggressive clinicopathologic characteristics may result in poor clinical outcomes. Although our study could not link IPLC histology to poor prognosis, considering the aggressive characteristics of IPLC, early detection and considerate treatment, including proper surgical and adjuvant intervention, could be helpful for disease progres

Pathology and Forensic MedicineMedicine
5
Article|32 citations·2013
Clinical Implication of Cancer Adhesion in Papillary Thyroid Carcinoma: Clinicopathologic Characteristics and Prognosis Analyzed with Degree of Extrathyroidal Extension
Seung Pil Jung, Minkuk Kim, Jun‐Ho Choe, Jee Soo Kim, Seok Jin Nam, Jung‐Han Kim, Jung‐Han Kim, Jung‐Han Kim
SJR Q1World Journal of Surgery

BACKGROUND: Macroscopic extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). However, intraoperative inspection for ETE is often inaccurate and could lead the surgeon to misconstrue simple adhesion as gross ETE. Such confusion could result in more aggressive treatment than necessary. In the present study we investigated the frequency and clinical implication of simple adhesions. METHODS: We identified 858 patients who underwent total thyroidectomy for

SurgeryMedicine
6
Article|32 citations·2013
A New Subfascial Approach in Open Thyroidectomy: Efficacy for Postoperative Voice, Sensory, and Swallowing Symptoms. A Randomized Controlled Study
Seung Pil Jung, Sung Hoon Kim, Soo Youn Bae, Se Kyung Lee, Sang‐Min Kim, Min-Young Choi, Jiyoung Kim, Minkuk Kim, Won Ho Kil, Jun-Ho Choe, Jung‐Han Kim, Seok Jin Nam
SJR Q1Annals of Surgical Oncology
SurgeryMedicine
7
Article|22 citations·2018
Lymph node ratio as an alternative to pN staging for predicting prognosis after neoadjuvant chemotherapy in breast cancer
Dong Hui Cho, Soo Youn Bae, Ji Young You, Hong Kyu Kim, Young Woo Chang, Yoo Jin Choi, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae, Seung Pil Jung
SJR Q2The Kaohsiung Journal of Medical SciencesOA

Axillary nodal status is one of the most important prognostic factors in breast cancer. The lymph node ratio (LNR) has been suggested as an independent prognostic factor because the number of dissected and involved lymph nodes might differ across institutions. Neoadjuvant chemotherapy (NAC) has been the preferred treatment method for reducing tumor mass in the breast and axillary area. However, NAC can reduce total number of excised lymph nodes compared with upfront surgery. Therefore, an emergi

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
Article|13 citations·2013
The Role of theCDH1Promoter Hypermethylation in the Axillary Lymph Node Metastasis and Prognosis
Seung Pil Jung, Sangmin Kim, Seok Jin Nam, Insun Kim, Jeoung Won Bae
SJR Q2Journal of Breast CancerOA

This study suggests that hypermethylation of the CDH1 gene may play a pivotal role in the metastasis of the axillary lymph node and the breast cancer recurrence.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|13 citations·2014
Primary Follicular Lymphoma in a Male Breast: A Case Report
Seung Pil Jung, Kang Min Han, Seok Jin Kim, Seok Jin Nam, Jeoung Won Bae, Jeong Eon Lee
SJR Q1Cancer Research and TreatmentOA

Primary breast lymphoma (PBL) is a rare disease, particularly in males. Diffuse large B cell lymphoma is the most common PBL, while follicular lymphoma is less common. Furthermore, primary follicular lymphoma of a male breast is rarely reported. We report a male patient with primary follicular lymphoma of the breast and hepatocellular carcinoma (HCC). A 46-year-old man was diagnosed with liver cirrhosis secondary to chronic hepatitis B infection. Ten years later, he underwent segmentectomy of th

Pathology and Forensic MedicineMedicine
10
Article|11 citations·2013
Primary breast lymphoma: a single institution's experience
Seung Pil Jung, Minkuk Kim, Kang Min Han, Jung‐Han Kim, Jee Soo Kim, Seok Jin Nam, Jeoung Won Bae, Jeong Eon Lee
Journal of the Korean Surgical SocietyOA

Most PBLs are B-cell origin, with DLBL being the most common histologic type. A combined treatment modality has been known to have positive effects on prognosis, and surgery should be limited to a diagnostic purpose.

Pathology and Forensic MedicineMedicine
11
Article|7 citations·2013
Validation of a Web-Based Tool to Predict the Ipsilateral Breast Tumor Recurrence (IBTR! 2.0) after Breast-Conserving Therapy for Korean Patients
Seung Pil Jung, Sung Mo Hur, Se Kyung Lee, Sangmin Kim, Min-Young Choi, Soo Youn Bae, Jiyoung Kim, Min Kuk Kim, Won Ho Kil, Jun-Ho Choe, Jung‐Han Kim, Jee Soo Kim
SJR Q2Journal of Breast CancerOA

In a previous validation of this nomogram based on American patients, nomogram-predicted IBTR rates were overestimated in the high-risk subgroup. However, our results based on Korean patients showed that the observed IBTR was higher than the predicted estimates in groups 3 and 4. This difference may arise from ethnic differences, as well as from the methods used to detect IBTR and the healthcare environment. IBTR! 2.0 may be considered as an acceptable nomogram in Korean patients with low- to mo

Cancer ResearchBiochemistry, Genetics and Molecular Biology
12
Article|6 citations·2013
Breast Metastasis from Rhabdomyosarcoma of the Anus in an Adolescent Female
Seung Pil Jung, Yoon Lee, Kang Min Han, Se Kyung Lee, Sangmin Kim, Soo Youn Bae, Jiyoung Kim, Minkuk Kim, Sinill Kim, Won Ho Kil, Hong Hoe Koo, Seok Jin Nam
SJR Q2Journal of Breast CancerOA

Rhabdomyosarcoma (RMS) of the breast is rare and there is scant information about the clinical behavior and treatment strategies. We report an adolescent female patient with metastatic RMS of the breast from the anus. An 18-year-old female patient was referred to our clinic due to palpable mass in the left breast. At age seven, she was diagnosed with acute lymphoblastic leukemia and treated with chemoradiation therapy. After 10 years of complete remission state, she presented with anal mass whic

Pulmonary and Respiratory MedicineMedicine
13
Article|6 citations·2025
Comparison of Surgical Outcomes in Robot-Assisted Nipple Sparing Mastectomy with Conventional Open Nipple Sparing Mastectomy: A Single Center Experience
Ji Young You, Young Min Kim, Eun-shin Lee, Haemin Lee, Seung Pil Jung
SJR Q1Journal of Clinical MedicineOA

Background: A surgical therapy for breast cancer, robot-assisted nipple-sparing mastectomy (RANSM) has gained popularity because it may offer better cosmetic results than traditional nipple-sparing mastectomy (CNSM). Data regarding RANSM’s viability and security are still scarce, nevertheless. Comparing the surgical results of RANSM and CNSM in a single-center experience was the goal of this study. Methods: 57 patients who had nipple-sparing mastectomy procedures performed at our facility betwee

SurgeryMedicine
14
letter|5 citations·2013
Recurrent intussusception caused by intestinal metastasis of pulmonary pleomorphic carcinoma
Seung Pil Jung, Kang Min Han, Jeoung Won Bae, Jung‐Han Kim
SJR Q2The Kaohsiung Journal of Medical SciencesOA

Dear Editor, Gastrointestinal metastasis from lung carcinoma is usually asymptomatic [1]. Due to the rarity of pleomorphic lung cancer, there have been only a few reports regarding symptomatic gastrointestinal metastasis from pulmonary pleomorphic carcinoma [2], [3]. Herein, we report a case of recurrent intussusception caused by multiple metastases of pulmonary pleomorphic carcinoma, with the hope that our experience will aid readers in clinical decision-making. A 63-year-old male visited the e

Pulmonary and Respiratory MedicineMedicine
15
Article|4 citations·2015
Medullary Thyroid Carcinoma Metastasis to the Breast and Axillary Lymph Nodes
Seung Pil Jung, Hye Yoon Lee, Jeoung Won Bae, Hoon Yub Kim
SJR Q4Indian Journal of SurgeryOA
Endocrinology, Diabetes and MetabolismMedicine

Research Areas

SurgeryOncologyCancer ResearchGeneticsPathology and Forensic MedicineEndocrinology, Diabetes and Metabolism

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