So Dam Lee

OBJECTIVE: may also contribute to gastric carcinogenesis, wild-type germ-free (GF) mouse models investigating the role of human gastric microbiota in the process are not yet available. We aimed to evaluate the histopathological features of GF mouse stomachs transplanted with gastric microbiota from patients with different gastric disease states and their relationships with the microbiota. DESIGN: Microbiota profiles in corpus and antrum tissues and gastric fluid from 12 patients with gastric dys

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Helicobacter pylori infection causes histopathologic changes in gastric epithelial cells, resulting in conditions such as gastritis, gastric ulcers, and ultimately, gastric cancer. To date, various experimental models, including cell lines and animal studies, have been employed to investigate these pathological processes. However, each model presents its limitations. This study compared the re-cultured three-dimensional organoids from infected single cells, apical-out, and two-dimensional (2D) o

본 연구는 보육교사의 일-삶 균형과 주관적 경력성공의 전반적 경향 및 변인에 따른 차이를 알아보고, 이들 간의 관계를 밝히는데 목적이 있었다. 연구대상은 어린이집에 근무하는 보육교사 208명이었으며, 연구도구로는 김정운, 박정열(2008)이 개발한 ‘일과 삶의 균형(Work-Life Balance)’ 척도와 Shockley 등(2016)이 개발한 ‘주관적 경력성공 척도(Subjective Career Success Inventory: SCSI)’를 보육교사에게 적합하게 수정․보완하여 사용하였다. 연구결과, 첫째, 보육교사의 일-삶 균형은 보통에 근접한 수준이었으며, 교사의 경력, 결혼여부, 월급여에 따라 일-삶의 균형 전체 혹은 하위요인에 유의한 차이가 있었다. 둘째, 보육교사의 주관적 경력성공은 보통보다 약간 높은 수준이었으며, 교사의 경력, 교육정도, 결혼여부, 기관유형, 근무시간, 월급여에 따라 주관적 경력성공 전체 혹은 하위요인에 유의한 차이가 있었다. 셋째, 보육교사의 일-

서산 지역 야철지에서 수습한 슬래그와 원광석의 재료적 특징을 알아보기 위해 금속현미경, SEM으로 미세조직을 관찰하였으며, XRF, EDS 분석을 이용한 성분분석을 실시하였다. XRD 분석을 통해 광물성분을 동정하였고 납 동위원소비 분석을 이용하여 원료의 산지를 추정하였다. 성분분석 결과 PbO, ZnO 등의 함량이 높게 검출되어 철 보다는 비철금속을 제련하는 과정에서 생성된 슬래그임을 알 수 있었다. 또한 슬래그의 주요조직은 Fayalite, Galena, Magnetite이며, 원광석은 Galena, Anglesite, Pyrite 등의 광물로 동정되었다. 납 동위원소비 분석 결과, 대부분 한반도 서부 경기지괴에 해당하며, 특히 원광석과 슬래그 중 3점은 한국 서부 경기지괴 중 시료가 수습된 위치인 서산 도성리가 산지로 추정되었다. 즉 이번에 분석한 슬래그는 제철 제련 과정이 아닌 비철금속을 제련할 때 생성된 것이며, 특히 서산 도성리에서 채굴한 원광석을 이용하여 비철금속을 제련

BACKGROUND & AIMS: Helicobactor pylori infection triggers a spectrum of metaplastic changes in the gastric epithelium; however, the upstream regulatory mechanisms remain unclear. In human gastric epithelial models, H pylori cytotoxin-associated gene A-dependent signaling stabilized and activated yes-associated protein, thereby promoting metaplastic reprogramming of the gastric epithelium. METHODS: Human gastric tissue specimens were obtained from patients at Severance Hospital, Yonsei University

This study aimed to investigate caregivers’ treatment satisfaction and clinical changes after the expansion of the additional reimbursement system for dental treatment for children with disabilities. A cross-sectional survey was conducted from April to May 2025 among 106 caregivers of pediatric patients with registered disabilities, including intellectual disability, brain lesion-related disabilities, and autism spectrum disorder. The 30-item questionnaire covered demographics, dental history, s

BACKGROUND: Regional odontodysplasia (RO) is a rare developmental dental anomaly with unknown prevalence. Current knowledge is largely limited to individual case reports. AIM: This study aims to present epidemiological data, clinical features, and radiographic characteristics of pediatric and adolescent patients with RO in South Korea. DESIGN: In this multicenter cohort study, we prospectively and retrospectively recruited participants from 11 university dental hospitals. Patients aged < 19 year

This study tried to empirically verify the relationship between adolescents' experience in human rights education and human rights abuse experiences such as hate discrimination. Human rights education among teenagers can have a positive effect not only on understanding the concept of human rights or improving human rights sensitivity, but also on recognizing and respecting differences from others through human rights education. While research on human rights education is centered on educational