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Soo-chang Cho

Ewha Womans University · Medicine

About the Lab

Professor Soo-chang Cho's research lab specializes in vitreo-retinal diseases, with a primary focus on the epidemiology, clinical characteristics, and risk factors of retinal vascular disorders such as polypoidal choroidal vasculopathy (PCV), neovascular age-related macular degeneration (nAMD), and choroidal neovascularization (CNV) in central serous chorioretinopathy. The lab also investigates surgical outcomes and treatment patterns in retinal detachment, particularly rhegmatogenous retinal detachment, using large-scale national health claims data. Their work emphasizes multimodal imaging, long-term clinical outcomes, and population-based incidence and risk factor analysis to guide clinical decision-making and improve patient management.

retinal vascular diseasepolypoidal choroidal vasculopathymacular holeepidemiologysurgical outcomes

Research Overview

Papers
23
Total Citations
237
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2022
2023
2024
2025
2026
Citations per year (5y)
28total
20222023202420252026

Selected Papers

15
1
Article|39 citations·2019
Risk Factors and Outcomes of Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy
Ga-In Lee, A. Young Kim, Se Woong Kang, Soo Chang Cho, Kyu Hyung Park, Sang Jin Kim, Kyung Tae Kim
SJR Q1Scientific ReportsOA

We identified clinical characteristics and risk factors of choroidal neovascularization (CNV) in eyes with prior episode of central serous chorioretinopathy (CSC). This retrospective case-control study included those initially diagnosed with CSC and developed CNV secondarily (Group 1, n = 16), those diagnosed with CNV in eyes of previous putative CSC (Group 2, n = 14), and those initially diagnosed with CSC, and did not develop CNV secondarily, as a control group for Group 1 (Group 3, n = 250).

OphthalmologyMedicine
2
Article|39 citations·2018
POSTTREATMENT POLYP REGRESSION AND RISK OF MASSIVE SUBMACULAR HEMORRHAGE IN EYES WITH POLYPOIDAL CHOROIDAL VASCULOPATHY
Joon Hee Cho, Young Joo Park, Soo Chang Cho, Na-Kyung Ryoo, Kwan Hyuk Cho, Sang Jun Park, Kyu Hyung Park, Se Joon Woo
SJR Q1RetinaOA

PURPOSE: To study the association between the risk of massive submacular hemorrhage (SMH) and polyp regression after initial treatment of polypoidal choroidal vasculopathy using long-term follow-up data. METHODS: Retrospective study of 223 patients who were diagnosed with polypoidal choroidal vasculopathy and were followed up for up to 11 years. Subjects were categorized into "regression" and "no regression" groups, according to their polyp status after the initial treatment. Kaplan-Meier surviv

OphthalmologyMedicine
3
Review|35 citations·2017
AGE, SEX, AND TIME-SPECIFIC TRENDS IN SURGICAL APPROACHES FOR RHEGMATOGENOUS RETINAL DETACHMENT
Sang Jun Park, Soo Chang Cho, Nam‐Kyong Choi, Kyu Hyung Park, Se Joon Woo
SJR Q1Retina

PURPOSE: To investigate the primary surgical approach for rhegmatogenous retinal detachment (RRD) according to age group, sex, and year in Korea. METHODS: We retrospectively identified patients from the national claims database who underwent primary surgery for RRD from 2007 to 2011 using the diagnostic code and surgical codes for RRD. Patients were categorized into three groups according to surgical treatment; scleral buckling, vitrectomy, and combined operation. We analyzed the frequency and p

Radiology, Nuclear Medicine and ImagingMedicine
4
Article|29 citations·2020
Massive submacular haemorrhage in polypoidal choroidal vasculopathy versus typical neovascular age‐related macular degeneration
Soo Chang Cho, JoonHee Cho, Kyu Hyung Park, Se Joon Woo
SJR Q1Acta OphthalmologicaOA

PURPOSE: To investigate the incidence rate of massive submacular haemorrhage (SMH) and risk factors in polypoidal choroidal vasculopathy (PCV) and typical neovascular age-related macular degeneration (tnAMD). METHODS: A total of 465 patients who were diagnosed with either PCV (n = 245) or tnAMD (n = 220) from 2003 to 2014 were enrolled. Cumulative incidence of massive SMH in PCV and that in tnAMD were compared. Risk factors of massive SMH were also analysed. RESULTS: Massive SMH occurred in 32 p

OphthalmologyMedicine
5
Article|27 citations·2013
Morphologic Characteristics of the Outer Retina in Cone Dystrophy on Spectral-domain Optical Coherence Tomography
Soo Chang Cho, Se Joon Woo, Kyu Hyung Park, Jeong‐Min Hwang
SJR Q2Korean Journal of OphthalmologyOA

The morphologic features of cone dystrophy as revealed by SD-OCT, could be categorized as either normal or 1 of 3 different types of outer retinal changes. The presence of normal retinal structures in young cone dystrophy patients with functional impairment (category 0) indicates that electrophysiologic studies are superior to current imaging modalities for the early diagnosis of cone dystrophy. The characteristic SD-OCT findings in cone dystrophy patients may aid in differential diagnosis and b

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
Article|18 citations·2019
Five-year nationwide incidence of macular hole requiring surgery in Korea
Soo Chang Cho, Sang Jun Park, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park
SJR Q1British Journal of Ophthalmology

BACKGROUND/AIMS: To estimate the incidence and demographics of macular hole (MH) requiring surgery in Korea. METHODS: Patients who underwent surgery for MH in Korea from 2011 to 2015 with the diagnostic code for MH and the surgical code for vitrectomy were retrospectively identified using the Korean national health claims database. The average incidence rate of MH during the 5-year study period was estimated by applying the direct method of standardisation using the 2015 census data as a referen

Radiology, Nuclear Medicine and ImagingMedicine
7
Review|15 citations·2017
RETINAL ARTERY OCCLUSION AFTER INTRAVASCULAR PROCEDURES
Soo Chang Cho, Cheolkyu Jung, Joo Yong Lee, Sang Jin Kim, Kyu Hyung Park, Se Joon Woo
SJR Q1Retina

PURPOSE: To evaluate clinical characteristics and possible mechanisms of retinal artery occlusion (RAO) after intravascular procedures. METHODS: This study is retrospective case series and literature review. Twenty-seven patients with intravascular procedure-associated RAO (10 new patients and 17 from previous reports) were divided into Groups 1 and 2 according to assumed etiology-dislodged and new emboli, respectively. Clinical features and etiology of RAO were analyzed. RESULTS: Branch and cen

OphthalmologyMedicine
8
Article|12 citations·2022
Agreement between Two Swept-Source Optical Coherence Tomography Biometers and a Partial Coherence Interferometer
Ji Young Moon, Soo Chang Cho, Hyun Jin Kim, Roo Min Jun, Kyung Eun Han
SJR Q2Korean Journal of OphthalmologyOA

PURPOSE: To evaluate the level of agreement between ANTERION (Heidelberg Engineering, Heidelberg, Germany), OA-2000 (Tomey, Nagoya, Japan), and IOLMaster 500 (Carl Zeiss AG, Jena, Germany). METHODS: Fifty-one eyes of 51 patients were included in the study. Flat keratometry (K) and steep K, vector component of astigmatism (Jackson cross-cylinder at 0° and 90° [J0] and Jackson cross-cylinder at 45° and 135° [J45]), anterior chamber depth, and axial length were compared using the three devices. Rep

EpidemiologyMedicine
9
Article|9 citations·2023
Discontinuation of treatment and retreatment of neovascular age-related macular degeneration in the real-world: Bundang AMD cohort study report 5
Soo Chang Cho, Kyu Hyung Park, Sang Jun Park, Kwangsic Joo, Se Joon Woo
SJR Q1Frontiers in MedicineOA

Introduction: This single-center retrospective cohort study investigated the incidence rate and risk factors for the discontinuation of anti-vascular endothelial growth factor (VEGF) injections and retreatment in typical neovascular age-related macular degeneration (tnAMD) and polypoidal choroidal vasculopathy (PCV) in the real-world setting. Methods: = 154) followed up for ≥3 years were analyzed. The discontinuation of treatment was defined as the cessation of anti-VEGF injections for 1 year or

OphthalmologyMedicine
10
Article|6 citations·2012
Three-Year Surgical Outcome of Exotropia
Soo Chang Cho, Hee Kyung Yang, Jeong Min Hwang
SJR Q4Journal of the Korean Ophthalmological SocietyOA

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Pathology and Forensic MedicineMedicine
11
Article|4 citations·2023
Repeatability and Agreement of Chord Mu between Scheimpflug Tomography and Swept-Source Optical Coherence Tomography
Na Hyun Kim, Hyun Jin Kim, Soo Chang Cho, Kyung Eun Han
SJR Q2Korean Journal of OphthalmologyOA

PURPOSE: To evaluate repeatability and agreement of chord mu between Scheimpflug tomography (Pentacam HR) and sweptsource optical coherence tomography-based optical biometer (IOLMaster 700). METHODS: In this retrospective study, 63 eyes from 33 patients were included. Chord mu, X and Y Cartesian distances between the corneal vertex and the pupil center (Px and Py), and the pupil diameter were compared using two instruments. Repeatability was evaluated using intraclass correlation coefficient (IC

Radiology, Nuclear Medicine and ImagingMedicine
12
Article|1 citations·2024
Two-year Outcomes of Intravitreal Aflibercept Injection for Neovascular Age-related Macular Degeneration with “Observe before Treat-and-Extend” Method
Ji Young Moon, Hyun Jin Kim, Soo Chang Cho
SJR Q2Korean Journal of OphthalmologyOA

PURPOSE: To evaluate 2-year outcomes of intravitreal aflibercept injection for neovascular age-related macular degeneration (nAMD) treated with "observe before treat-and-extend (O-TAE)" strategy in the real-world setting. METHODS: This retrospective study included treatment-naive nAMD patients treated with aflibercept using O-TAE regimen and followed up for more than 2 years. Patients were observed bimonthly to check recurrence after three monthly loading injections. In case of recurrence, treat

OphthalmologyMedicine
13
Article|1 citations·2020
Association of Irregular Pigment Epithelial Detachment in Central Serous Chorioretinopathy with Genetic Variants Implicated in Age-related Macular Degeneration
Soo Chang Cho, Na-Kyung Ryoo, Jeeyun Ahn, Se Joon Woo, Kyu Hyung Park
SJR Q1Scientific ReportsOA

We evaluated phenotype and genotype correlation of central serous chorioretinopathy (CSC) patients with or without irregular pigment epithelial detachment (PED) on optical coherence tomography (OCT). For CSC, a flat, irregular protrusion of retinal pigment epithelium (RPE) with hyper-reflective sub-RPE fluid on OCT was defined as an irregular PED. Participants were classified into 5 subgroups; (1) total CSC (n = 280) (2) CSC with irregular PED (n = 126) (3) CSC without irregular PED (n = 154) (4

OphthalmologyMedicine
14
Article|1 citations·2023
Comparison of Horizontal White-to-white Diameter Measured Using Four Devices
Da Eun Yoon, Soo Chang Cho, Hyun Jin Kim, Kyung Eun Han
SJR Q4Journal of the Korean Ophthalmological SocietyOA

Purpose: To compare the horizontal white-to-white (WTW) diameter measured using four devices.Methods: We measured the horizontal WTW diameter of 52 eyes of 52 patients using the IOL Master 500, ANTERION, OA-2000, and Pentacam HR devices. Repeated-measures analysis of variance was used to compare the measurements. Correlations between the measurements were evaluated using the Pearson correlation test. Agreement between measurements obtained using different instruments was confirmed using a Bland-

EpidemiologyMedicine
15
Article|1 citations·2022
External Subretinal Fluid Drainage and Vitrectomy in Exudative Retinal Detachment Secondary to Central Serous Chorioretinopathy: A Case Report
Ji Young Moon, Soo Chang Cho, Se Joon Woo
SJR Q2Korean Journal of OphthalmologyOA
OphthalmologyMedicine

Research Areas

OphthalmologyRadiology, Nuclear Medicine and ImagingEpidemiologyMolecular BiologyPathology and Forensic MedicineNeurology

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