Sung-Bum Kang
Seoul National University · Medicine
About the Lab
Professor Sung-Bum Kang's research lab specializes in regenerative medicine and surgical innovation, with a primary focus on tissue engineering and stem cell therapy for musculoskeletal and pelvic floor disorders. The lab investigates the potential of autologous stem cells and engineered muscle tissues to restore function in conditions such as anal sphincter dysfunction and volumetric muscle loss. Key research directions include nerve reinnervation of engineered tissues, the surgical learning curve in laparoscopic colorectal surgery, and perioperative outcomes in rectal cancer patients. The lab also explores clinical applications of minimally invasive techniques and risk factors for postoperative complications such as acute urinary retention.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15This is the first study reporting that autologous muscle-derived stem cell grafts may be a tool for improving anal sphincter function.
BACKGROUND: Although several risk factors for acute urinary retention after rectal cancer surgery have been proposed, few studies have enrolled a homogeneous group of patients without preoperative urinary dysfunction. We aimed to identify risk factors and preventive measures for acute urinary retention after rectal cancer surgery. METHODS: This study was a retrospective review of prospectively collected data from included patients who underwent rectal cancer surgery at a single center. Preoperat
Nontraumatic perforation of the bile duct should be suspected if perihepatic abscess or peritonitis is combined with biliary stone disease. The management of nontraumatic perforation of the bile duct should include the eradication of the primary pathologic lesion and the control of abscess or peritonitis.
BACKGROUND: Wide-ranging costs of laparoscopic surgery (LAP) are associated with variations in the experience levels of surgeons. There is no available report on the changes of economic outcomes relative to the LAP learning curve in the treatment of colorectal cancer. In the present study, we have compared changes in economic outcomes according to the LAP learning curve with the economic outcomes of open surgery (OS) for rectosigmoid cancer. METHODS: A total of 197 patients with rectosigmoid can
Seoul National University Bundang Hospital, Korea.
Tissue-engineered muscle has been proposed as a solution to repair volumetric muscle defects and to restore muscle function. To achieve functional recovery, engineered muscle tissue requires integration of the host nerve. In this study, we investigated whether denervated muscle, which is analogous to tissue-engineered muscle tissue, can be reinnervated and can recover muscle function using an in vivo model of denervation followed by neurotization. The outcomes of this investigation may provide i
BACKGROUND: We conducted a randomized clinical trial to investigate the efficacy of the selective α(1A)-adrenoceptor antagonist tamsulosin in preventing acute voiding difficulty after rectal cancer surgery. METHODS: A total of 94 rectal cancer patients with an International Prostate Symptom Score (IPSS) of ≤7 were randomly assigned (1:1) to the tamsulosin group (0.2 mg/day orally for 7 days) (n = 47) or the control group (n = 47). The primary endpoint was the reinsertion rate of the urinary cath
Research Areas
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