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Sung-Ha Park

Sungkyunkwan University · Physics and Astronomy

About the Lab

Professor Sung-Ha Park's research lab specializes in nanobiotechnology, focusing on the design, fabrication, and application of DNA-based nanostructures and hybrid nanomaterials. The lab explores DNA self-assembly for creating functional 1D and 2D nanostructures, such as open tubes and lattices, which are integrated with nanomaterials like carbon nanotubes and hydroxyapatite for sensing and biomedical applications. A key direction involves developing highly sensitive biosensors, including fiber-optic reflectance sensors using DNA thin films, for detecting bio-aerosols and biomolecules. The lab also investigates the integration of biopolymers and inorganic materials to create stable, functional coatings and composite films for advanced technological applications.

DNA nanotechnologybiosensorsnanocomposite filmsself-assemblybiomaterials

Research Overview

Papers
24
Total Citations
91
Papers (5y)
12
Primary Field
Physics and Astronomy

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2014
2015
2017
2018
2019
Citations per year (5y)
35total
20142015201720182019

Selected Papers

15
1
Article|18 citations·2012
Electrophoretic deposition of PVA coated hydroxyapatite on 316L stainless steel
Nida Iqbal, Rabia Nazir, Anila Asif, Aqif Anwar Chaudhry, Muhammad Akram, Goh Yi Fan, Aftab Akram, Rashid Amin, 박성하, Rafaqat Hussain

Polyvinyl alcohol (PVA) coated hydroxyapatite was deposited onto a 316L stainless steel substrate by electrophoretic deposition. Deposition was carried out in a methanol suspension at pH 5.5 using a graphite rod as an anode. Parameters such as PVA concentration, deposition voltage and time were optimized to achieve a homogeneous, crack-free adhesive coating. Techniques such as X-ray diffraction and Fourier transform infrared spectroscopy were used to study the phase composition of the coated mat

2
Article|15 citations·2018
DNA and DNA–CTMA composite thin films embedded with carboxyl group-modified multi-walled carbon nanotubes
Sreekantha Reddy Dugasani, GNAPAREDDYBRAMARAMBA, Mallikarjuna Reddy Kesama, 하태환, 박성하

Although the intrinsic characteristics of DNA molecules and carbon nanotubes (CNT) are well known, fabrication methods and physical characteristics of CNT-embedded DNA thin films are rarely investigated. We report the construction and characterization of carboxyl (–COOH) group-modified multi-walled carbon nanotube (MWCNT–COOH)-embedded DNA and cetyltrimethyl-ammonium chloride-modified DNA (DNA–CTMA) composite thin films. Here, we examine the structural, compositional, chemical, spectroscopic, an

3
Article|14 citations·2012
DNA thin film coated optical fiber biosensor
Rashid Amin, 아툴, 김태성, 박성하

We present a simple but highly sensitive biotinylated DNA double crossover thin film coated fiber optic reflectance biosensor (DTF FORS) for the detection of streptavidin aerosols as a building block towards sensing bio-aerosols. The DNA double crossover lattice with biotin was dropped on the polymer optical fiber end face to prepare DNA Thin Film. The streptavidin aerosols were prepared using conventional aerosol technology. The DTF FORS response to streptavidin aerosol was few seconds and the

4
Article|10 citations·2009
ARTIFICIALLY DESIGNED DNA NANOSTRUCTURES
박성하, RASHID AMIN, SOYEON KIM, THOMAS HENRY LABEAN

In the field of structural DNA nanotechnology, researchers create artificial DNA sequences to self-assemble into target molecular superstructures and nanostructures. The well-understood Watson–Crick base-pairing rules are used to encode assembly instructions directly into the DNA molecules. A wide variety of complex nanostructures has been created using this method. DNA directed self-assembly is now being adapted for use in the nanofabrication of functional structures for use in electronics, pho

5
Article|6 citations·2011
NANOBIOTECHNOLOGY: AN INTERFACE BETWEEN NANOTECHNOLOGY AND BIOTECHNOLOGY
RASHID AMIN, SIEUN HWANG, 박성하

Nanotechnology is one of the most important emerging fields of science in this century. It deals with designing, construction, investigation, and utilization of systems at the nanoscale. Another interesting research discipline of current day is biotechnology, which gives us a way to understand biological system and to utilize our knowledge for industrial manufacturing. Nanobiotechnology lies at the interface of these two research fields. It exploits nanotechnology and biotechnology to analyze an

6
Article|5 citations·2015
Streptavidin bound DNA open tube and Zn2+-doped DNA open lattice
Srivithya Vellampatti, Sekhar Babu Mitta, 김장아, 황태현, 레디, 김태성, 박성하

DNA is one of the most promising molecules for use in nanotechnology because it has a nanoscale size and also has the ability for self-assembly. In this paper, we discuss the use of free-solution growth for a 1D DNA open tube (OT) and substrate-assisted growth for a 2D open lattice (OL), which can both achieve similar design schemes.We introduced biotinylated OT and OL, which can be bound with streptavidin for visualization, to verify via atomic force microscopy that dimensional structures have

7
Article|4 citations·2012
Structural and functional stabilities of artificially designed DNA ultra-thin films grown by silica Assistance
이준휘, 구종현, 황시운, 민선민, 안상정, 노용한, 박성하

We report the structural and functional stabilities of artificially synthesized DNA ultra-thin films. Fully covered DNA ultra-thin films on a silica substrate were fabricated by the silica-assisted growth method and those samples were then incubated in various chemicals and physical conditions. The DNA ultra-thin films showed high maintainability under those harsh conditions and these results would aid to facilitate the use of artificial DNA ultra-thin films in advanced research areas such as bi

8
Article|4 citations·2017
Electrical properties of polycrystalline and single crystalline nickel layer capped ZnO nanowires
Devika Mudusu, Koteeswara Reddy Nandanapalli, 레디, 강장원, 박성하, CharlesW. Tu

This article reports the electrical characteristics of pristine, polycrystalline and single crystalline nickel (Ni) layer capped zinc oxide (ZnO) nanowires. Core/shell ZnO/Ni nanostructures were developed using chemical vapor deposition and e-beam evaporation, and the structures were annealed at different temperatures. Field effect transistor (FET) devices were fabricated using photolithography and investigated their characteristics at room temperature. All FET devices exhibited depletion-mode c

9
Article|3 citations·2014
현대중국어 양태조동사 ‘要’의 어법특성 분석 - 주어와의 공기여부를 중심으로 -
박성하

本文通过对现代汉语情态助动词“要”能否与主语同现的分析来考察“要”的语法特征。首先根据‘要’的情态意义来进行类型分类。其中,动力情态分为“意志”和“意图”;道义情态分为“强义务”和“弱义务”,“强义务”又分为“自然道理”和“环境要求”,“弱义务”又分为“劝告”,“命令”和“规范”;认识情态分为“常识”,“可能”,“推断”和“预测(复合预测,单纯预测)”。通过对以上各类的分析发现,动力情态不能与第二人称和非生命主语同现,道义情态中强义务与主语同现使用时所受到的制约比弱义务更多。而认识情态与动力情态及道义情态相比,所受到的制约相对较少。

10
Article|3 citations·2017
Structural stability and electrical characteristic of DNA lattices doped with lanthanide ions
레디, GNAPAREDDYBRAMARAMBA, 김장아, 유상현, 황태현, 김태성, 박성하

The main aim of doping DNA lattices with lanthanide ions (Ln-DNA complex) is to change the physical functionalities for specific target applications such as electronics and biophotonics. LneDNA complexes based on a double-crossover DNA building block were fabricated on glass using a substrate-assisted growth method. We demonstrated the structural stability of LneDNA complexes as a function of Ln ion concentration by the atomic force microscopy. The Ln ion doping in DNA lattices was examined usin

11
Article|3 citations·2015
Surface enhanced Raman scattering based molecule detection using self-assembled DNA nanostructures
김명순, 이준외, 레디, 허남, 박성하, 박상철

A novel method of Surface Enhanced Raman Scattering (SERS) based molecular detection was developed using self-assembled DNA nanostructures. Molecule detection using rigid, shape-controllable DNA nanostructures provides significant advantages such as accurate control of the particle distance and geometrical programmability of the DNA nanostructure.We successfully detected the Cy3 dye, a Ramanactive molecule, at 1461, 1590, and 1619 cm-1 using a Ag-enhanced Au-DNA nanostructure. Consequently, DNA-

12
Article|2 citations·2012
Photoresistivity and optical switching of graphene with DNA lattices
아툴, Rashid Amin, 김형근, 홍병희, 박성하, 김태성

We present the photon induced conductivity of 2D DNA lattices with and without graphene and demonstrate the switching current responses controlled by light irradiation. The conductivity in the DNA lattices with protein streptavidin controlled by blue and white lights shows significant enhancement with the addition of graphene. An optical pulse response of a graphene immobilized DNA lattice is encouraging and may lead to various bio-sensing applications such as immunological assays, DNA forensics

13
Article|1 citations·2015
Coverage percentage and coverage rate of different DNA nanostructures grown on a mica substrate
Saima Bashar, 김승재, 황시운, 레디, 하태환, 박성하

In this study, we simultaneously grew different DNA nanostructures, including 5 helix ribbon (5HR), double-crossover (DX), and double-crossover with single hairpin (DX-SH) lattices, on a mica substrate, and we analyzed the concentration-dependent coverage percentages of 5HR at a fixed concentration of DX ([DX]), DX at a fixed [5HR], and DX-SH with both fixed [5HR] and [DX]. The structural features of the various nanostructures formed through mica-assisted growth annealing were confirmed via atom

14
Article|1 citations·2014
현대중국어 ‘就要’와 ‘快要’의 어법특성 비교
박성하

本文通过对现代汉语"就要"、"快要"能否与其他语法成分共现的分析来考察"就要"、"快要"的语法特征的区别。首先根据"就要"、"快要"的情态意义来进行类型分析。其中,"就要"拥有动力情态、道义情态、认识情态,可是"快要"只有认识情态。这就是说明"就要"、"快要"的内部结构不一样,因此它们的语法特征也不一样。其次根据"就要"、"快要"的共现副词及时间词 来进行分析发现,"就要"注重事情的关连性和主观性,"快要"注重事情的时间性。最后根据"就要"、"快要"的共现助词"了"来进行分析发现,"快要"与"就要"相比,所受到的制约相对较少。通过对以上共现情况的分析发现,这些"快要"与"就要"共现情况的不同反映了它们的语法特征的不同。

15
Article|1 citations·2011
ENHANCEMENT OF SURFACE PLASMON RESONANCE USING COLLOIDAL GOLD NANOPARTICLES EMBEDDED IN A SILICA LAYER
정재연, 최재유, JIE CHENG, 박민성, 조성인, 현진호, 박성하

This paper presents a strategy for the signal enhancement of surface plasmon resonance biosensors using colloidal gold nanoparticles and a silica layer. We describe the method for the deposition of a silica-stabilized gold nanoparticle layer on a gold film, namely an enhanced surface plasmon resonance chip. This chip shows significant changes in its surface plasmon resonance signals when biomolecules are attached to its surface as compared to a normal gold surface. These characteristics are clos

Research Areas

Radiation

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