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Sung Yeon Ham

Yonsei University · Medicine

About the Lab

Professor Sung Yeon Ham's research lab specializes in critical care anesthesiology and perioperative medicine, focusing on optimizing patient outcomes in high-risk surgical populations. Key research directions include the prediction of postoperative mortality using hematological biomarkers such as neutrophil-to-lymphocyte ratio (NLR) and mean platelet volume (MPV), as well as investigating pharmacological strategies to reduce complications like emergence agitation, dental injury, and opioid-induced chest wall rigidity. The lab also explores the impact of anesthetic agents—such as dexmedetomidine—on hemodynamic stability, airway management, and recovery quality in patients undergoing major surgery.

perioperative mortalityhematological biomarkerscritical care anesthesiologyairway complicationsdexamethasone

Research Overview

Papers
40
Total Citations
267
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2021
2022
2023
2024
2025
Citations per year (5y)
44total
20212022202320242025

Selected Papers

15
1
Article|30 citations·2015
Aprepitant for antiemesis after laparoscopic gynaecological surgery
Sung Yeon Ham, Yon Hee Shim, Eun Ho Kim, Min Ji Son, W. S. Park, Jeong Soo Lee
SJR Q1European Journal of AnaesthesiologyOA

Clinicaltrial.gov identifier: NCT01897337.

SurgeryMedicine
2
Article|26 citations·2014
Dexmedetomidine does not reduce emergence agitation in adults following orthognathic surgery
Sung Yeon Ham, J. E. Kim, C. Park, Myung‐Jun Shin, Yon Hee Shim
SJR Q2Acta Anaesthesiologica ScandinavicaOA

The addition of a single dose of dexmedetomidine (1 μg/kg) to low-dose remifentanil infusion did not attenuate emergence agitation in intubated patients after orthognathic surgery compared with low-dose remifentanil infusion alone. However, single-dose dexmedetomidine suppressed coughing, haemodynamic changes, and pain during emergence and recovery phases, without respiratory depression. Delayed awakening might be associated with this treatment.

Anesthesiology and Pain MedicineMedicine
3
Article|24 citations·2016
Risk factors for peri‐anaesthetic dental injury
Sung Yeon Ham, Jeongmin Kim, Young Jun Oh, Byung Seok Lee, Yong Sam Shin, Sungwon Na
SJR Q1AnaesthesiaOA

In this retrospective case-control study, we evaluated peri-operative dental injury risk factors following tracheal intubation. Ninety-four of 290,415 patients experienced dental injury following tracheal intubation over a 10-y period. A control group was matched for surgery type and intubating anaesthetist. The incidence of dental injury was 0.03%. Univariate analysis revealed that previous and current difficult intubation, male gender, hepatitis, neurological disease, anticonvulsant use, pre-e

Anesthesiology and Pain MedicineMedicine
4
Article|23 citations·2020
Prognostic value of neutrophil/lymphocyte ratio and mean platelet volume/platelet ratio for 1-year mortality in critically ill patients
Sung Yeon Ham, Hei Jin Yoon, Sang Beom Nam, Byung Hwan Yun, Darhae Eum, Cheung Soo Shin
SJR Q1Scientific ReportsOA

Several studies have reported that the neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) are associated with poor prognosis. This study investigated whether NLR and/or the MPV/platelet ratio could function as predictive markers of mortality in critically ill patients. We retrospectively reviewed 1,154 patients admitted to the intensive care unit (ICU) between January 2017 and December 2017. Patients were divided into 2 groups according to 1-year mortality. We compared the NLR a

OncologyMedicine
5
Article|11 citations·2021
Preoperative Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio, and Mean Platelet Volume as Predictors of 1-Year Mortality in Patients Undergoing an Open Repair of Abdominal Aortic Aneurysms: A Retrospective Study
Da Eun Ko, Hei Jin Yoon, Sang Beom Nam, Suk‐Won Song, Gisong Lee, Sung Yeon Ham
SJR Q1Journal of Clinical MedicineOA

Objectives: To investigate if preoperative neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), or mean platelet volume (MPV) could be used to predict 1-year mortality in patients undergoing open abdominal aortic aneurysm (AAA) repair. Methods: We retrospectively reviewed 382 patients who underwent open AAA repair between January 2008 and July 2019. We divided the patients into two groups based on 1-year mortality and compared the preoperative NLR, PLR, and MPV. The patients

OncologyMedicine
6
Article|10 citations·2016
Recurrent Desaturation Events due to Opioid-Induced Chest Wall Rigidity after Low Dose Fentanyl Administration
Sung Yeon Ham, Bo Ra Lee, Taehoon Ha, Jeongmin Kim, Sungwon Na
Korean Journal of Critical Care MedicineOA

Opioid-induced chest wall rigidity is an uncommon complication of opioids. Because of this, it is often difficult to make a differential diagnosis in a mechanically ventilated patient who experiences increased airway pressure and difficulty with ventilation. A 76-year-old female patient was admitted to the intensive care unit (ICU) after surgery for periprosthetic fracture of the femur neck. On completion of the surgery, airway pressure was increased, and oxygen saturation fell below 95% after a

Critical Care and Intensive Care MedicineMedicine
7
Article|8 citations·2018
Comparison of Perioperative Renal Function Between Epidural and Intravenous Patient-Controlled Analgesia After Living-Donor Hepatectomy: A Retrospective Study
Sung Yeon Ham, Eun Jung Kim, T.H. Kim, Bon‐Nyeo Koo
SJR Q3Transplantation ProceedingsOA
SurgeryMedicine
8
Article|6 citations·2024
Myocardial Injury after Non-Cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: A Retrospective Study
Myung Il Bae, Tae-Hoon Kim, Hei Jin Yoon, Suk‐Won Song, Nar Hyun Min, Jongyun Lee, Sung Yeon Ham
SJR Q1Journal of Clinical MedicineOA

Background: Myocardial injury after non-cardiac surgery (MINS) has been known to be associated with mortality in various surgical patients; however, its prognostic role in abdominal aortic aneurysm (AAA) open repair remains underexplored. This study aimed to investigate the role of MINS as a predictor of mortality in patients who underwent AAA open repair. Methods: This retrospective study investigated 352 patients who underwent open repair for non-ruptured AAA. The predictors of 30-day and 1-ye

Cardiology and Cardiovascular MedicineMedicine
9
Article|6 citations·2022
Regulators impeding erythropoiesis following iron supplementation in a clinically relevant rat model of iron deficiency anemia with inflammation
Sung Yeon Ham, Ji Hae Jun, Hye-Bin Kim, Jae‐Kwang Shim, Gisong Lee, Young Lan Kwak
SJR Q1Life SciencesOA
HematologyMedicine
10
Article|5 citations·2018
Effects of chronic statin use on 30-day major adverse cardiac and cerebrovascular events after thoracic endovascular aortic repair
Sung Yeon Ham, Suk‐Won Song, Sang Beom Nam, Soo Jung Park, Sijin Kim, Young Song
SJR Q2The Journal of Cardiovascular SurgeryOA

In patients undergoing TEVAR, chronic statin use was associated with reduced 30-day MACCEs in non-AAS patients, but not in AAS patients. It might rather be associated with increased risk of AKI in AAS patients.

Pulmonary and Respiratory MedicineMedicine
11
Article|5 citations·2018
Prognostic role of carotid intima-media thickness in off-pump coronary artery bypass surgery
Sung Yeon Ham, Jong Wook Song, Jae‐Kwang Shim, Sarah Soh, Hee Jung Kim, Young Lan Kwak
SJR Q1Scientific ReportsOA

Carotid intima-media thickness (IMT) is a well-known predictor of adverse outcomes in the ischemic heart disease patients; however, evidence is lacking in patients undergoing off-pump coronary artery bypass surgery (OPCAB). Data from 407 patients who underwent OPCAB between April 2013 and August 2016 were retrospectively reviewed. A composite of cardiovascular morbidity endpoints was defined as the presence of stroke, acute myocardial infarction, new cardiac arrhythmia (newly developed atrial fi

Cardiology and Cardiovascular MedicineMedicine
12
Article|4 citations·2024
Effects of dexmedetomidine on renal function after cardiac surgery for infective endocarditis: An interim analysis of a randomized controlled trial
Sung Yeon Ham, Jae‐Kwang Shim, Sak Lee, Seo Hee Ko, Sarah Soh, Young Lan Kwak
SJR Q2Asian Journal of SurgeryOA

Dexmedetomidine administration for 24 h starting from induction of anesthesia significantly reduced the incidence of postoperative AKI after cardiac surgery for IE (by 29 % vs. control) without hemodynamic side effects. This was accompanied by a significant attenuation of postoperative increase in serum epinephrine levels.

EpidemiologyMedicine
13
Article|3 citations·2013
The effect of combining aprepitant with ondansetron in high-risk patients for postoperative nausea and vomiting; preliminary study
Sung Yeon Ham, J. E. Kim, Young Lan Kwak, W. S. Park, Yon Hee Shim
SJR Q1European Journal of Anaesthesiology
SurgeryMedicine
14
Article|3 citations·2018
Age-Related Difference in the Effect of Acute Hyperglycemia on Myocardial Ischemia-Reperfusion Injury
Sung Yeon Ham, Sang Beom Nam, Young Lan Kwak, Tae Lim Kim, Jong-Kwang Park, Yon Hee Shim
SJR Q1The Journals of Gerontology Series AOA

Age and acute hyperglycemia are known risk factors of myocardial ischemia-reperfusion injury. We investigated age-related difference in the effect of acute hyperglycemia on myocardial ischemia-reperfusion injury in Sprague-Dawley rats (young, 3 months; middle-aged, 10-12 months; and old, 22-24 months). The rats received 1.2 g/kg dextrose or normal saline and were subjected to coronary artery occlusion for 45 minutes followed by reperfusion for 240 minutes. Infarct size and ejection fraction were

EpidemiologyMedicine
15
Article|2 citations·2023
Postoperative Hypoalbuminemia as a Predictor of Acute Kidney Injury After Open Repair of Ruptured Abdominal Aortic Aneurysm
Hei Jin Yoon, Tae‐Hoon Kim, Da Eun Ko, Jong Wook Song, Nar Hyun Min, Sung Yeon Ham
SJR Q1World Journal of Surgery

BACKGROUND: Perioperative hypoalbuminemia has a prognostic effect on mortality and morbidity in various cohorts. Patients undergoing open repair of ruptured abdominal aortic aneurysms (rAAA) are at a high risk of hypoalbuminemia due to bleeding and underlying diseases. Hence, this study aimed to investigate the predictive value of immediate postoperative hypoalbuminemia for the risk for acute kidney injury (AKI) in patients undergoing open rAAA repair. METHODS: We retrospectively reviewed 143 pa

Critical Care and Intensive Care MedicineMedicine

Research Areas

SurgeryAnesthesiology and Pain MedicineCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineCritical Care and Intensive Care MedicineNephrology

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