Sungyeon Seo
Ewha Womans University · Medicine
About the Lab
Professor Sungyeon Seo's research lab specializes in clinical pharmacology and anticoagulation therapy, with a focus on optimizing anticoagulant management in vulnerable patient populations. The lab investigates the pharmacokinetics and safety of direct oral anticoagulants like edoxaban in patients with renal impairment and low body weight, aiming to improve individualized dosing strategies. Additional research directions include the use of time-in-therapeutic-range (TTR) as a predictor for post-discharge anticoagulation outcomes, particularly in patients following acute coronary syndromes. The lab integrates clinical data and real-world evidence to enhance patient safety and treatment efficiency.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
3Although edoxaban has a broad therapeutic window that does not require routine monitoring, it should be cautiously used in patients with renal insufficiency (CrCl <50 mL/min) and body weight <60 kg.
The study implicated that high postoperative TTR would reduce the time to require post-discharge target INR and the number of ACS visits.
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Research Areas
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