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Tack Kyun Kwon

Seoul National University · Medicine

About the Lab

Professor Tack Kyun Kwon's research lab specializes in laryngeal phonosurgery and injectable laryngoplasty, focusing on the clinical application and long-term safety of biomaterials such as calcium hydroxylapatite (CaHA) and hyaluronic acid (HA) for vocal fold augmentation. The lab investigates the radiological behavior of these injectables using CT and PET imaging, evaluates their efficacy in conditions like presbylaryngis and unilateral vocal fold paralysis, and explores the immunogenetic basis of laryngeal diseases such as recurrent respiratory papillomatosis. A key emphasis is placed on office-based, minimally invasive procedures performed under local anesthesia, with long-term outcomes and complication profiles analyzed over a decade of clinical practice.

laryngoplastycalcium hydroxylapatitevocal fold paralysisinjectable laryngoplastyphonosurgery

Research Overview

Papers
145
Total Citations
2,416
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2022
2023
2024
2025
2026
Citations per year (5y)
52total
20222023202420252026

Selected Papers

15
1
Review|174 citations·2004
Injection laryngoplasty for management of unilateral vocal fold paralysis
Tack‐Kyun Kwon, Robert A. Buckmire
SJR Q2Current Opinion in Otolaryngology & Head & Neck Surgery

In recent years, the application of injection laryngoplasty to unilateral vocal fold paralysis (UVP) has regained popularity. The technique of injection laryngoplasty has several appealing qualities including relative technical ease, low cost, and wide availability in many clinical settings. A growing number of injectable substances have been developed and tested in the clinical setting of glottic insufficiency. When used to manage unilateral vocal fold paralysis, however, injection laryngoplast

PhysiologyMedicine
2
Article|48 citations·2009
Calcium hydroxylapatite injection laryngoplasty for the treatment of presbylaryngis: Long‐term results
Tack‐Kyun Kwon, Soo‐Youn An, Jae‐Cheul Ahn, Kwang Hyun Kim, Myung‐Whun Sung
SJR Q1The Laryngoscope

OBJECTIVES/HYPOTHESIS: Presbylaryngis is a normal part of the aging process, but many people visit hospitals with communication difficulties. The authors evaluated the efficacy of calcium hydroxylapatite (CaHA) injection laryngoplasty in patients with presbylaryngis. STUDY DESIGN: Retrospective review. METHODS: Thirty-three patients with diagnosed presbylaryngis were administered a CaHA injection, and 17 of these patients without other vocal pathologies were included in the analysis. All 17 were

PhysiologyMedicine
3
Article|43 citations·2012
Reliability and validity of the Korean version of Pediatric Voice Handicap Index: In school age children
Sung Shin Park, Tack‐Kyun Kwon, Seong Hee Choi, Won Yong Lee, Young Hye Hong, Nyun Gi Jeong, Myung‐Whun Sung, Kwang Hyun Kim
SJR Q2International Journal of Pediatric Otorhinolaryngology
PhysiologyMedicine
4
Article|37 citations·2005
Preliminary Results of a New Temporary Vocal Fold Injection Material
Tack‐Kyun Kwon, Clark A. Rosen, Jackie Gartner‐Schmidt
SJR Q2Journal of Voice
PhysiologyMedicine
5
Article|24 citations·2019
Safety of office‐based percutaneous injection laryngoplasty with calcium hydroxylapatite
Minhyung Lee, Doh Young Lee, Tack‐Kyun Kwon
SJR Q1The Laryngoscope

OBJECTIVE: To evaluate the safety of office-based calcium hydroxylapatite (CaHA) injection laryngoplasty via the cricothyroid approach through an analysis of all procedures performed over a period of 10 years at a single institution. METHODS: In total, 962 office-based CaHA injection laryngoplasty via the cricothyroid approach procedures were performed by a single physician at our institution between 2007 and 2016. From these, 955 procedures performed in 617 patients were included in our analysi

PhysiologyMedicine
6
Article|22 citations·2019
Natural Course of Unilateral Vocal Fold Paralysis and Optimal Timing of Permanent Treatment
Dong‐Han Lee, Sang-Youp Lee, Minhyung Lee, Jungirl Seok, Sung Joon Park, Young Ju Jin, Doh Young Lee, Tack‐Kyun Kwon
SJR Q1JAMA Otolaryngology–Head & Neck SurgeryOA

A linear association between injury level and maximum recovery time was observed. The findings suggest that the decision to proceed with permanent phonosurgical treatment should be based on the level of injury associated with UVFP.

PhysiologyMedicine
7
Article|17 citations·2013
Serial computed tomographic and positron emission tomographic properties of injection material used for vocal fold augmentation
Tack‐Kyun Kwon, Jieun Lee, Wonjae Cha, Chang Myeon Song, Myung‐Whun Sung, Kwang Hyun Kim
SJR Q1The Laryngoscope

OBJECTIVES/HYPOTHESIS: This study aimed to demonstrate the radiological properties of hyaluronic acid (HA) and calcium hydroxylapatite (CAHA) on serial computed tomography (CT) and positron emission tomography (PET) scan. STUDY DESIGN: Retrospective Case Series. METHOD: Retrospective chart and imaging analysis of patients who underwent HA or CAHA injection laryngoplasty. RESULT: Total of 243 patients who underwent more than one CT of PET after last injection laryngoplasty were included. Sixty-ei

PhysiologyMedicine
8
Article|15 citations·2012
The Korean version of the University of Washington Quality of Life Questionnaire for Patients with Head and Neck Cancer, and its use in an initial validation study of 56 patients
Mun Young Chang, S.N. Rogers, D. Lowe, Woo‐Jin Jeong, Wonjae Cha, Kun Taek Park, Dongwook Kim, Hak Chang, M.W. Sung, Kyae Hyung Kim, Tack‐Kyun Kwon
SJR Q1International Journal of Oral and Maxillofacial Surgery
OtorhinolaryngologyMedicine
9
Article|10 citations·2017
Associations of FoxP3 gene polymorphisms with severe recurrent respiratory papillomatosis in Korean patients
Tack‐Kyun Kwon, Eun Jae Chung, Nuri Lee, Eun Youn Roh, Eun Young Song
SJR Q1Journal of Otolaryngology - Head and Neck SurgeryOA

BACKGROUND: FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infections. We studied the association of Foxp3 polymorphisms in severe RRP patients. METHODS: A total of 30 Korean severe RRP patients and 195 healthy controls were enrolled. Foxp3 polymorphisms (rs5902434 del/ATT, rs3761548 C/A, rs3761549 C/T, and rs2232365 G/A) were determined by PCR

ImmunologyImmunology and Microbiology
10
Article|8 citations·2020
Prediction of Malignancy in Salivary Gland Tumors by a New Cytology Reporting System
Doh Young Lee, Seulki Song, Seung Koo Yang, Min Hyung Lee, Ji Eun Kim, Young Ho Jung, Tack‐Kyun Kwon
SJR Q3Ear Nose & Throat JournalOA

Objectives: The aim of this study was to analyze the risk of malignancy in salivary gland tumors on the basis of the Milan System for Reporting Salivary Gland Cytopathology. Methods: A retrospective review was performed of the charts of patients with salivary gland tumors in whom the final diagnosis was confirmed by surgical excision. Preoperative fine needle aspiration results were categorized according to the Milan System for Reporting Salivary Gland Cytopathology: non-diagnostic (category I),

SurgeryMedicine
11
Article|7 citations·2013
Associations of HLA-DRB1 and -DQB1 alleles with severe recurrent respiratory papillomatosis in Korean patients
Eun Young Song, Sue Shin, Kyoung Un Park, Myoung Hee Park, Myung‐Whun Sung, Kwang Hyun Kim, Tack‐Kyun Kwon
SJR Q2Human Immunology
ImmunologyImmunology and Microbiology
12
Article|6 citations·2024
Evaluating the Diagnostic Potential of Connected Speech for Benign Laryngeal Disease Using Deep Learning Analysis
Jeong Hoon Lee, Jungirl Seok, Jae Yeong Kim, Hee Chan Kim, Tack‐Kyun Kwon
SJR Q2Journal of Voice
PhysiologyMedicine
13
Article|4 citations·2007
Development of Endoscopic Arytenoid Adduction Using Cricoid Implant
Tack‐Kyun Kwon, Woo‐Jin Jeong, Myung‐Whun Sung, Kwang Hyun Kim
SJR Q2Annals of Otology Rhinology & Laryngology

OBJECTIVES: We sought to develop a less-invasive alternative to conventional arytenoid adduction using a cricoid implant. METHODS: We performed a preliminary study with excised human and canine larynges. A nail-shaped stainless steel rod and an insertion device were designed for an in vivo animal trial. After unilateral recurrent laryngeal denervation surgery in 5 adult mongrel dogs, the implants were inserted endoscopically through a small mucosal incision over the cricoarytenoid joint. Acousti

PhysiologyMedicine
14
Article|4 citations·2012
Tracheal growth after airway stenosis surgery: Serial radiographic comparative study
Woong Sang Sunwoo, Wonjae Cha, Chang Myeon Song, Myung‐Whun Sung, Kwang Hyun Kim, Tack‐Kyun Kwon
SJR Q2Acta Oto-Laryngologica

In all, 24 patients were treated with the endoscopic technique. Among the six open laryngotracheal reconstructions, cricoid splitting and rib cartilage graft were performed in four patients and laryngotracheal resection and end-to-end anastomosis were performed in two patients. Stenosis to normal ratio tended to increase after endoscopic intervention, but it did not show statistical significance (p = 0.082). Open surgery did not cause significant narrowing (p = 0.443).

Pulmonary and Respiratory MedicineMedicine
15
Article|3 citations·2020
Prognostic value of the posterior cricoarytenoid muscle atrophy in computerized tomography scans for unilateral vocal fold paralysis recovery
Doh Young Lee, Dmitriy Kogay, Seulki Song, Ye Ji Shim, Bo Hae Kim, Young Ju Jin, Seong Dong Kim, Yewon Kim, Eun Jae Chung, Tack‐Kyun Kwon
SJR Q1European Archives of Oto-Rhino-Laryngology
PhysiologyMedicine

Research Areas

PhysiologyOtorhinolaryngologySurgerySpeech and HearingGastroenterologyPulmonary and Respiratory Medicine

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