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Tae Hee Oh

Sungkyunkwan University · Medicine

About the Lab

Professor Tae Hee Oh's research lab focuses on neurotrophic factors and their role in neuromuscular regulation, particularly the molecular mechanisms underlying muscle maintenance and acetylcholinesterase regulation. The lab investigates trophic proteins such as sciatin, isolated from peripheral nerves, to understand their influence on muscle function and survival in both embryonic and denervated adult muscle cultures. The research also extends into clinical applications, including the evaluation of surgical outcomes in cardiac valve surgery and minimally invasive surgical techniques, reflecting a translational approach from basic neurobiology to clinical surgery. The lab integrates cell biology, immunohistochemistry, and clinical data analysis to explore nerve-muscle interactions and surgical innovation.

neurotrophic factorsacetylcholinesterasemuscle maintenancesciatinminimally invasive surgery

Research Overview

Papers
135
Total Citations
1,481
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2017
2018
2019
2021
2022
Citations per year (5y)
43total
20172018201920212022

Selected Papers

15
1
Article|69 citations·1976
Neurotrophic effects of sciatic nerve extracts on muscle development in culture
Tae Hee Oh
SJR Q1Experimental Neurology
PharmacologyMedicine
2
Article|62 citations·1972
Neurotrophic Effect on Isolated Chick Embryo Muscle in Culture
Tae Hee Oh, David Johnson, S. U. Kim
SJR Q1Science

Acetylcholinesterase activity in cultures of dissociated skeletal muscle prepared from the thigh muscle of the 10-day-old chick embryo was increased by the presence of innervating spinal cord explants, spinal cord explants in a parabiotic environment, and by media containing brain-spinal cord extract.

PharmacologyMedicine
3
Article|55 citations·1975
Neurotrophic effects: Characterization of the nerve extract that stimulates muscle development in culture
Tae Hee Oh
SJR Q1Experimental Neurology
PharmacologyMedicine
4
Article|51 citations·1977
Comparison of Nasotracheal Intubation and Tracheostomy in Management of Acute Epiglottitis
Tae Hee Oh, Etsuro K. Motoyama
SJR Q1AnesthesiologyOA

Acute epiglottitis is a life-threatening respiratory emergency of early childhood. The disease may progress so rapidly that complete upper airway obstruction occurs within hours.1 Trachostomy has been the procedure of choice2–4 to relieve airway obstruction; however, in recent years several investigators have reported the encouraging results of nasotracheal intubation5–12 as an alternate procedure in the management of acute epiglottitis. The purpose of this report is to evaluate the relative eff

Pulmonary and Respiratory MedicineMedicine
5
Article|41 citations·1978
Neurotrophic Protein Regulates Muscle Acetylcholinesterase in Culture
Tae Hee Oh, GJ Markelonis
SJR Q1Science

Skeletal muscles lose acetylcholinesterase in culture as a result of denervation. A protein fraction isolated from peripheral nerves maintained the level of acetylcholinesterase in cultures of aneural embryonic muscle or denervated adult chicken muscle. These results indicate that trophic regulation of muscle acetylcholinesterase might be mediated by a protein produced by nerves.

PharmacologyMedicine
6
Article|36 citations·1981
Sciatin: immunocytochemical localization of a myotrophic protein in chicken neural tissues.
Tae Hee Oh, Carmen Sofía, Y C Kim, Chad C. Carroll, H H Kim, George J. Markelonis, Paul J. Reier
SJR Q1Journal of Histochemistry & Cytochemistry

A mytotrophic protein (sciatin) purified from chicken sciatic nerves has "trophic" or "maintenance" effects on cultured muscle. We have elicited a specific antiserum against purified sciatin in rabbits. Using this antiserum, we investigated the distribution of sciatin in embryonic and adult chicken tissues by an unlabeled peroxidase-an-tiperoxidase method at the light microscopic level. The antiserum stained adult chicken neural tissues in situ and cultured embryonic chick neurons. Staining was

NeurologyNeuroscience
7
letter|36 citations·1980
Formulas for Calculating Fluid Maintenance Requirements
Tae Hee Oh
SJR Q1AnesthesiologyOA
Mechanical EngineeringEngineering
8
Article|31 citations·2013
Isolated tricuspid valve surgery at a single centre: the 47-year Auckland experience, 1965-2011
Tae Hee Oh, Tom KM Wang, Karishma Sidhu, David Haydock
SJR Q2Interactive Cardiovascular and Thoracic SurgeryOA

OBJECTIVES: Isolated tricuspid valve surgery is not commonly performed with few studies and limited numbers published. We reviewed the characteristics and outcomes, including survival, reoperation rates and their predictors of different types of isolated tricuspid surgery. METHODS: Patients coded for isolated tricuspid valve surgery were identified from the Green Lane Hospital database. Relevant clinical characteristics were collected from both clinical and written clinical records. Mortality wa

Cardiology and Cardiovascular MedicineMedicine
9
Article|12 citations·1977
Acute Epiglottis Associated with Nasal Foreign Body
Tae Hee Oh, Thomas Gaudet
SJR Q3Clinical Pediatrics
Radiology, Nuclear Medicine and ImagingMedicine
10
Article|4 citations·2012
Current Status of Laparoendoscopic Single-Site Surgery in Urologic Surgery
Tae Hee Oh
Korean journal of urologyOA

Since the introduction of laparoscopic surgery, the promise of lower postoperative morbidity and improved cosmesis has been achieved. Laparoendoscopic single-site surgery (LESS) potentially takes this further. Following the first human urological LESS report in 2007, numerous case series have emerged, as well as comparative studies comparing LESS with standard laparoscopy. However, comparative series between conventional laparoscopy and LESS for different procedures suggest a non-inferiority of

SurgeryMedicine
11
Article|1 citations·1988
Immunocytochemical localization of aldolase in normal, denervated, and dystrophic chicken muscles.
Tae Hee Oh, Benjamin W. C. Rosser, Charles R. Shear, Y C Kim, George J. Markelonis
SJR Q1Journal of Histochemistry & Cytochemistry

To investigate whether immunocytochemical localization of muscle-specific aldolase can be used for fiber phenotype determination, we produced specific antibodies against the enzyme and studied its distribution in adult chicken skeletal muscles by indirect immunofluorescence microscopy. Monoclonal antibodies against the myosin heavy chains of fast-twitch (MF-14) and slow-tonic (ALD-58) muscle fibers were also used to correlate aldolase levels with the fiber phenotype. The goat anti-aldolase antib

Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
Article|1 citations·1987
PROLONGED PT AND PTT DESPITE ADEQUATE HEPARIN NEUTRALIZATION FOLLOWING CARDIOPULMONARY BYPASS IN CHILDREN
Tae Hee Oh, C. Bell, Cían Hughes
SJR Q1AnesthesiologyOA
SurgeryMedicine
13
Article|1 citations·2012
Current Status of Laparoendoscopic Single-Site Surgery in Urologic Surgery
오태희

Since the introduction of laparoscopic surgery, the promise of lower postoperative morbidity and improved cosmesis has been achieved. Laparoendoscopic single-site surgery (LESS) potentially takes this further. Following the first human urological LESS report in 2007, numerous case series have emerged, as well as comparative studies comparing LESS with standard laparoscopy. However, comparative series between conventional laparoscopy and LESS for different procedures suggest a non-inferiority of

14
Article|0 citations·2010
1083 RETROPERITONEAL LAPAROENDOSCOPIC SINGLE SITE (LESS) RADICAL NEPHRECTOMY: COMPARISON WITH CONVENTIONAL LAPAROSCOPIC SURGERY
Tae Hee Oh, Dong Soo Ryu, Hee Chang Jung
SJR Q1The Journal of Urology

You have accessJournal of UrologyTechnology & Instruments: Robotics/Laparoscopy/Ureteroscopy III1 Apr 20101083 RETROPERITONEAL LAPAROENDOSCOPIC SINGLE SITE (LESS) RADICAL NEPHRECTOMY: COMPARISON WITH CONVENTIONAL LAPAROSCOPIC SURGERY Tae Hee Oh, Dong Soo Ryu, and Hee Chang Jung Tae Hee OhTae Hee Oh Masan, Republic of Korea More articles by this author , Dong Soo RyuDong Soo Ryu Masan, Republic of Korea More articles by this author , and Hee Chang JungHee Chang Jung Daegu, Republic of Korea More

Pulmonary and Respiratory MedicineMedicine
15
Article|0 citations·2007
Clinical Manifestations and Indications for Management of Ureteroceles in Adults
Tae Hee Oh, Dong Soo Ryu, Jun O Kwon
Korean Journal of Urology

Purpose: To review the clinical manifestations, indications and the management outcomes of adult patients with ureteroceles. Materials and Methods: Between 1995 and 2006, 20 adult patients (9 females, 3 males) with ureteroceles were investigated for their clinical symptoms, type of ureterocele and renal function. The outcomes of surgical or conservative management, according to the patients' symptoms were also individually analyzed. The median follow-up was 38 months (12-50 months). Results: The

Pediatrics, Perinatology and Child HealthMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryUrologyAnesthesiology and Pain MedicineRheumatologyPharmacology

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