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Tae-jin Song

Ewha Womans University · Medicine

About the Lab

Professor Tae-jin Song's research lab specializes in population health sciences, focusing on the epidemiological burden of chronic non-communicable diseases with a particular emphasis on musculoskeletal disorders, headache disorders, periodontal disease, and their systemic implications. The lab conducts large-scale, population-based cohort studies using national health datasets to investigate the interplay between oral health, systemic inflammation, and conditions such as stroke, gastrointestinal cancer, and motor neuron disease. Key research directions include understanding the role of oral hygiene and periodontal disease as modifiable risk factors for major chronic diseases, and assessing the global and national trends in disease burden using data from the Global Burden of Disease Study. The lab integrates epidemiology, biostatistics, and health policy to inform public health interventions and healthcare planning.

oral healthdisease burdenpopulation cohortperiodontitissystemic inflammation

Research Overview

Papers
299
Total Citations
3,549
Papers (5y)
159
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
159total
2022
2023
2024
2025
2026
Citations per year (5y)
1,375total
20222023202420252026

Selected Papers

15
1
Article|117 citations·2022
Global, regional, and national neck pain burden in the general population, 1990–2019: An analysis of the global burden of disease study 2019
Dong Woo Shin, Jae Il Shin, Ai Koyanagi, Louis Jacob, Lee Smith, Heajung Lee, Yoonkyung Chang, Tae‐Jin Song
SJR Q2Frontiers in NeurologyOA

Background: This study describes the global epidemiology and trends associated with neck pain. Global Burden of Disease data collected between 1990 and 2019 were used to determine the global burden of neck pain in the general populations of 204 countries. Methods: Global, regional, and national burdens of neck pain determined by prevalence, incidence, and years lived with a disability (YLD) from 1990 to 2019 were comprehensively analyzed according to age, gender, and socio-demographic index usin

PharmacologyMedicine
2
Article|104 citations·2020
Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study
Yoonkyung Chang, Ji Sung Lee, Ki-Jung Lee, Ho Geol Woo, Tae‐Jin Song
SJR Q1DiabetologiaOA
PeriodonticsDentistry
3
Article|101 citations·2016
Anxiety and Depression in Tension-Type Headache: A Population-Based Study
Tae‐Jin Song, Soo‐Jin Cho, Won‐Joo Kim, Kwang Ik Yang, Chang‐Ho Yun, Min Kyung Chu
SJR Q1PLoS ONEOA

Although tension-type headache (TTH) is a frequent type of headache disorder and imposes a significant burden, there is scant information about the prevalence and impact of comorbid anxiety and depression among individuals with TTH. We investigated the prevalence and clinical impact of anxiety and depression among patients with TTH in the general population. We recruited Korean participants aged 19-69 years using a two-stage clustered random sampling method. To identify the presence of headache

Psychiatry and Mental healthMedicine
4
Article|99 citations·2016
Moderate-to-severe obstructive sleep apnea is associated with cerebral small vessel disease
Tae‐Jin Song, Jung‐Hyun Park, Kang Hyun Choi, Yoonkyung Chang, Jangsup Moon, Juhee Kim, Yunseo Choi, Yong‐Jae Kim, Hyang Woon Lee
SJR Q1Sleep Medicine
PhysiologyMedicine
5
Article|88 citations·2020
Better oral hygiene is associated with lower risk of stroke
Yoonkyung Chang, Ho Geol Woo, Ji Sung Lee, Tae‐Jin Song
SJR Q1Journal of Periodontology

BACKGROUND: Periodontal disease or poor oral hygiene may lead to local infection, inflammation, and systemic inflammatory reactions, which are important mediators of development of stroke. We aimed to investigate the association of oral hygiene with risk of stroke in a nationwide population-based cohort. METHODS: From Korean National Health Insurance System-Health Screening Cohort, 206,602 participants without missing data regarding demographic information, medical history, or blood/urine examin

PeriodonticsDentistry
6
Article|88 citations·2020
Oral health and gastrointestinal cancer: A nationwide cohort study
Kijeong Lee, Ji Sung Lee, Jinkwon Kim, Huisong Lee, Yoonkyung Chang, Ho Geol Woo, Jin‐Woo Kim, Tae‐Jin Song
SJR Q1Journal Of Clinical Periodontology

AIMS: Poor oral hygiene is closely associated with bacteraemia and systemic inflammation, which are known mediators of cancer development. We investigated the relationship between oral hygiene indicators and the risk of gastrointestinal cancer in a nationwide population-based cohort. MATERIALS AND METHODS: This study was conducted on data from 150,774 subjects from the Korean National Health Screening Cohort. The occurrence of gastrointestinal cancer was analysed according to the presence of per

PeriodonticsDentistry
7
Article|73 citations·2022
The Global Burden of Motor Neuron Disease: An Analysis of the 2019 Global Burden of Disease Study
Jin Park, Jee‐Eun Kim, Tae‐Jin Song
SJR Q2Frontiers in NeurologyOA

Up-to-date, accurate information on the disease burden of motor neuron disease (MND) is the cornerstone for evidence-based resource allocation and healthcare planning. We aimed to estimate the burden of MND globally from 1990 to 2019, as part of the Global Burden of Disease, Injuries and Risk Factor (GBD) study. Amyotrophic lateral sclerosis, progressive muscular atrophy, primary lateral sclerosis, pseudobulbar palsy, spinal muscular atrophy and hereditary spastic paraplegia- were included for a

NeurologyMedicine
8
Article|60 citations·2020
Oral health and changes in lipid profile: A nationwide cohort study
Tae‐Jin Song, Jin‐Woo Kim, Jin‐Woo Kim, Jinkwon Kim, Jinkwon Kim
SJR Q1Journal Of Clinical Periodontology

AIM: We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. MATERIALS AND METHODS: We included nationwide health screening program participants who underwent oral health examination in 2009-2010 and follow-up examinations for lipid profile without exposure to lipid-lowering agents. RESULTS: During the 5.19-year median follow-up, 65,078 individuals (mean age at

PeriodonticsDentistry
9
Article|55 citations·2021
Microbiota dysbiosis and functional outcome in acute ischemic stroke patients
Yoonkyung Chang, Ho Geol Woo, Jee Hyang Jeong, Geon Ha Kim, Kee Duk Park, Tae‐Jin Song
SJR Q1Scientific ReportsOA

Currently, few studies are reported on the composition of microbiota in stroke patients and the association with stroke prognosis. This study investigated the differing microbiota composition in stroke patients and confirmed the association of microbiota composition with poor functional outcome. Between January of 2018 and December of 2019, 198 patients with acute cerebral infarction were included in this study. For the case-control study, age and sex-matched normal healthy subjects (n = 200) we

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|54 citations·2022
Burden of neurological diseases in Asia from 1990 to 2019: a systematic analysis using the Global Burden of Disease Study data
Seungji Kang, Seuhyun Eum, Yoonkyung Chang, Ai Koyanagi, Louis Jacob, Lee Smith, Jae Il Shin, Tae‐Jin Song
SJR Q1BMJ OpenOA

OBJECTIVES: The burden of neurological disorders is increasing worldwide, including Asia. The purpose of this study was to determine the burden of neurological disorders between 1990 and 2019 in Asia using the Global Burden of Disease (GBD) Sociodemographic Index. DESIGN, SETTING, OUTCOME AND PARTICIPANTS: The GBD Study is updated every year and the most recent version provides the burden of diseases according to age, gender and region from 1990 to 2019. The burden of neurological disorders was

Pathology and Forensic MedicineMedicine
11
Article|53 citations·2022
Association of triglyceride-glucose index with prognosis of COVID-19: A population-based study
Yoonkyung Chang, Jimin Jeon, Tae‐Jin Song, Jinkwon Kim
SJR Q1Journal of Infection and Public HealthOA

In COVID-19 infected patients, high TyG index was associated with increased risk for severe complications. TyG index might be useful predictor for the severity of COVID-19 infection.

Infectious DiseasesMedicine
12
Article|52 citations·2018
Poor sleep quality in migraine and probable migraine: a population study
Tae‐Jin Song, Soo‐Jin Cho, Won‐Joo Kim, Kwang Ik Yang, Chang‐Ho Yun, Min Kyung Chu
SJR Q1The Journal of Headache and PainOA

Poor sleep quality was prevalent among participants with PM. It was associated with an exacerbation of PM symptoms. Our findings suggest that proper evaluation and treatment for poor sleep quality are needed in the management of PM.

Psychiatry and Mental healthMedicine
13
Article|52 citations·2016
Anxiety and depression in probable migraine: A population-based study
Tae‐Jin Song, Soo‐Jin Cho, Won‐Joo Kim, Kwang Ik Yang, Chang‐Ho Yun, Min Kyung Chu
SJR Q1CephalalgiaOA

Background Although probable migraine (PM) is common among headache sufferers, there is little knowledge of the prevalence and impacts of comorbid anxiety and depression in patients with PM. We assessed the prevalence and impact of anxiety and depression among PM sufferers in the general population. Methods We recruited Korean individuals aged 19-69 years via stratified random sampling and assessed headache type, anxiety, and depression among them using structured interviews. Results In a repres

Psychiatry and Mental healthMedicine
14
Review|49 citations·2021
Exercise in Treatment of Migraine Including Chronic Migraine
Tae‐Jin Song, Min Kyung Chu
SJR Q1Current Pain and Headache ReportsOA
Psychiatry and Mental healthMedicine
15
Article|46 citations·2021
Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study
Tae‐Jin Song, Yoonkyung Chang, Jimin Jeon, Jinkwon Kim
SJR Q1PLoS ONEOA

We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health screening program with oral health check in 2009-2010. We constructed a linear mixed model for the longitudinal data of fasting glucose from the baseline to 2015. During the 4.84-year of median follow-up,

PeriodonticsDentistry

Research Areas

Psychiatry and Mental healthCardiology and Cardiovascular MedicineEpidemiologySurgeryNeurologyPhysiology

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