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Won Kyung Pyo

Yonsei University · Medicine

About the Lab

Professor Won Kyung Pyo's research lab specializes in cardiovascular surgery and structural heart disease, with a strong focus on optimizing surgical outcomes and improving long-term results in patients with valvular heart disease. Key research directions include perioperative risk management in patients undergoing valve surgery, the impact of postoperative antibiotic duration on infective endocarditis outcomes, and the biomechanical performance of bioprosthetic aortic valves, particularly in relation to strut design and leaflet coaptation. The lab also investigates modifiable risk factors such as physical activity in diabetic patients to reduce the incidence of infective endocarditis, integrating clinical data with advanced computational modeling.

aortic valve replacementinfective endocarditisbioprosthetic valvesperioperative outcomesstructural heart disease

Research Overview

Papers
18
Total Citations
62
Papers (5y)
17
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
17total
2019
2020
2021
2023
2024
Citations per year (5y)
61total
20192020202120232024

Selected Papers

15
1
Article|11 citations·2021
Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis
Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung‐Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
SJR Q2Korean Circulation JournalOA

PVE carried significant perioperative risks, and was an independent risk factor of overall mortality.

EpidemiologyMedicine
2
Article|9 citations·2021
Does Surgical Ablation of Atrial Fibrillation Benefit Patients Undergoing Bioprosthetic Valve Replacement?
Won Kyung Pyo, Ho Jin Kim, Ho Jin Kim, Sung‐Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee, Jae Won Lee
SJR Q1Seminars in Thoracic and Cardiovascular Surgery
Cardiology and Cardiovascular MedicineMedicine
3
Article|6 citations·2023
Impact of the Duration of Postoperative Antibiotics on the Prognosis of Patients with Infective Endocarditis
Jin Nam Kim, Jung Ho Kim, Hi Jae Lee, Se Ju Lee, Changhyup Kim, Jung Ah Lee, Ki Hyun Lee, Won Kyung Pyo, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Seung Hyun Lee
SJR Q1AntibioticsOA

Appropriate postoperative antibiotic treatment in patients with infective endocarditis (IE) reduces the risks of recurrence and mortality. However, concerns about adverse drug reactions arise due to prolonged antibiotic usage. Therefore, we compared the recurrence and mortality rates according to the duration of postoperative antibiotic therapy in patients with IE. From 2005 to 2017, we retrospectively reviewed 416 patients with IE treated at a tertiary hospital in South Korea; among these, 216

EpidemiologyMedicine
4
Article|5 citations·2021
Mini-access open arch repair
Shi A Kim, Won Kyung Pyo, You Jung Ok, Ho Jin Kim, Joon Bum Kim
SJR Q2Journal of Thoracic DiseaseOA

Mini-access open arch repair is technically feasible and achieved excellent early outcomes.

Pulmonary and Respiratory MedicineMedicine
5
Article|5 citations·2024
Effect of physical activity on risk reduction of infective endocarditis among patients with diabetes: a nationwide cohort study
Se Ju Lee, Hee Jung Kim, Jin Nam Kim, Won Kyung Pyo, Jung Ho Kim, Jin Young Ahn, Su Jin Jeong, Jun Yong Choi, Joon‐Sup Yeom, Kyungdo Han, Nam Su Ku, Seung Hyun Lee
SJR Q1Scientific ReportsOA

Patients with diabetes mellitus (DM) are at a higher risk of infectious diseases, and exercise is an important treatment modality for DM. Despite their susceptibility to infection in diabetic patients, the association between the amount of physical activity and the incidence of infective endocarditis (IE) is unclear. We attempted to demonstrate risk reduction by physical activity in diabetic patients with IE. From the National Health Insurance database, patients with DM were verified, and the in

EpidemiologyMedicine
6
Article|4 citations·2021
Comparison of Sutureless Bioprosthetic Valve With Surgical or TAVR for Severe Aortic Stenosis
Ho Jin Kim, Do‐Yoon Kang, Hanbit Park, Jung‐Min Ahn, Joon Bum Kim, Seon‐Ok Kim, You Jung Ok, Seung Hun Lee, Won Kyung Pyo, Euihong Ko, Seung‐Ah Lee, Dae‐Hee Kim
SJR Q1JACC AsiaOA

In this propensity-matched cohort of patients who underwent AVR for severe AS, we did not detect significant differences in the rates of the primary composite of death, stroke, or rehospitalization at 12 months when comparing RD-AVR with SAVR and TAVR. Because the study was underpowered, the results should be considered as hypothesis generating highlighting the need for further research. (ASAN Medical Center Aortic Valve Replacement Registry [ASAN-AVR]; NCT03298178).

Cardiology and Cardiovascular MedicineMedicine
7
Article|4 citations·2021
Sarcoma Resection With Complete Removal of Left Atrial Posterior Wall
Won Kyung Pyo, Joon Bum Kim
SJR Q1The Annals of Thoracic Surgery
Cardiology and Cardiovascular MedicineMedicine
8
Article|4 citations·2024
A parametric study regarding structural design of a bioprosthetic aortic valve by 3D fluid-structure interaction simulations
Yongwoo Kim, Won Kyung Pyo, Wan Kee Kim, Ga‐Young Suh, Keonwook Kang, Seung Hyun Lee
SJR Q1HeliyonOA

Since the introduction of transcatheter aortic valve (AV) implantation as a viable option, surgical bioprosthetic AVs have recently started incorporating shorter struts considering future valve-in-valve procedures. However, the effect of leaflet coaptation geometry on the longevity of these valves remains unexplored. To address this gap, we performed a finite element analysis on bioprosthetic AVs with varying strut heights using a two-way fluid-structure interaction method. To establish a baseli

Cardiology and Cardiovascular MedicineMedicine
9
Article|4 citations·2019
A Huge Pericardial Gossypiboma Causing Severe Cardiac Dysfunction
Won Kyung Pyo, Wan Kee Kim, Joon Bum Kim
SJR Q1The Annals of Thoracic Surgery
HematologyMedicine
10
Article|3 citations·2020
Surgical Treatment for Left Main Coronary Atresia with Significant Mitral Regurgitation in a 1-Year-Old Child
Seung Woo Ryu, Won Kyung Pyo, Eun Seok Choi, Chun Soo Park, Jeong Jin Yu, Tae-Jin Yun, Cheol Hyun Chung
SJR Q3Journal of Chest SurgeryOA

Congenital atresia of the left main coronary artery (LMCA) is an extremely rare coronary anomaly that necessitates surgical correction. Patients with LMCA atresia may have various clinical symptoms, which are determined by the degree of collateral vessel development from the right coronary system, the metabolic demands of the heart, and concomitant mitral insufficiency caused by myocardial ischemia. Unlike in adults, there are limited surgical options for coronary artery disease in children. Her

Pulmonary and Respiratory MedicineMedicine
11
Article|3 citations·2021
Large primary cardiac tumor penetrating the right ventricle: 3-dimensional printing-based surgical planning
Eunji Kim, Won Kyung Pyo, Dong Hyun Yang, Joon Bum Kim
SJR Q2JTCVS TechniquesOA

Central MessageA 3-dimensional printing model may be an important guiding tool for establishing surgical planning in complex cardiac tumors.See Commentaries on pages 41 and 43. A 3-dimensional printing model may be an important guiding tool for establishing surgical planning in complex cardiac tumors. See Commentaries on pages 41 and 43. The primary cardiac tumor is extremely rare, constituting 0.3% to 0.7% of all cardiac tumors.1Castello J. Silvay G. Characterization and management of cardiac t

Cardiology and Cardiovascular MedicineMedicine
12
Article|2 citations·2024
Association between weight changes and infective endocarditis in patients with diabetes: A nationwide population-based cohort study
Jung Ho Kim, Se Hee Park, Se Ju Lee, Jin Nam Kim, Won Kyung Pyo, Hee‐Jung Kim, Jin Young Ahn, Su Jin Jeong, Jun Yong Choi, Joon‐Sup Yeom, Kyungdo Han, Nam Su Ku
SJR Q1International Journal of ObesityOA

BACKGROUNDS: The association between weight change in patients with diabetes, and the development of infective endocarditis (IE) has never been studied. Therefore, we evaluated the associations of weight changes in patients with diabetes with the development of IE. METHODS: In this Korean population-based cohort study, we included patients with diabetes aged ≥20 years who underwent health screenings twice in a 2-year interval between 2009 and 2012. Patients were categorized into five groups acco

EpidemiologyMedicine
13
Article|1 citations·2024
The risk of infective endocarditis according to blood pressure in patients with diabetes: a nationwide population-based study
Won Kyung Pyo, Hee Jung Kim, Kyungdo Han, Jin Nam Kim, Se Ju Lee, Jung Ho Kim, Nam Su Ku, Seung Hyun Lee
SJR Q1Clinical HypertensionOA

Diabetic patients may require rigorous blood pressure control and simultaneous avoidance of excessive weight loss to prevent IE.

EpidemiologyMedicine
14
Article|1 citations·2017
Recurrent Mediastinal Sarcoma in the Aortic Arch
Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

As mediastinal sarcomas commonly present as large tumors invading adjacent vital structures, complete resection is frequently challenging. For such tumors, aggressive surgical strategies, such as the resection and reconstruction of the invaded vital structures under cardiopulmonary bypass, may be required to achieve complete resection and to improve survival. Herein, we report a case of recurrent mediastinal sarcoma invading the aortic arch and arch vessels that was successfully removed by total

Cardiology and Cardiovascular MedicineMedicine
15
letter|0 citations·2021
Commentary: Extracorporeal membrane oxygenation (ECMO) in the coronavirus disease 2019 (COVID-19) pandemic; When, how, and to whom
Won Kyung Pyo, Joon Bum Kim
SJR Q1JTCVS OpenOA

Central MessageFurther research regarding to ECMO use may provide answers to its optimal allocation and effective use in the COVID-19 pandemic.See Article page 77. Further research regarding to ECMO use may provide answers to its optimal allocation and effective use in the COVID-19 pandemic. See Article page 77. The coronavirus disease 2019 (COVID-19) pandemic has been extended longer than half a year, causing millions of deaths. As immunization coverage has increased, the primary goal of medica

Biomedical EngineeringEngineering

Research Areas

Cardiology and Cardiovascular MedicineEpidemiologyPulmonary and Respiratory MedicineHematologyBiomedical Engineering

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