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Wonkyung Cho

Sungkyunkwan University

About the Lab

Professor Wonkyung Cho's research lab specializes in translational oncology and radiation oncology, focusing on the management of oligometastatic and unresectable cancers through advanced radiation therapy techniques. The lab investigates the biological and clinical effects of combined therapies—such as radiation with pharmacological agents like captopril—and explores the role of immune modulation in tumor microenvironments. Additionally, the lab contributes to legal and ethical frameworks in medical and financial contexts, particularly regarding patient rights, data privacy, and investment regulations in healthcare. These interdisciplinary efforts reflect a commitment to improving cancer treatment outcomes while addressing broader societal and regulatory implications.

radiation oncologyoligometastatic diseasecancer therapyimmunomodulationoncology ethics

Research Overview

Papers
8
Total Citations
2
Papers (5y)
8
Primary Field

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
8total
2015
2016
2023
2024
2025
Citations per year (5y)
2total
20152016202320242025

Selected Papers

8
1
Article|1 citations·2023
Differential Perspectives by Specialty on Oligometastatic Colorectal Cancer: A Korean-Oligometastasis Working Group’s Comparative Survey Study
조원경, 유규상, 임채홍, 정재욱, 지의규, 안용찬, 조현민, 엄준원, 서양권, 장아람, 이종훈, On behalf of the Oligometastasis Working Group, Korean Cancer Associat

Purpose Despite numerous studies on the optimal treatments for oligometastatic disease (OMD), there is no established interdisciplinary consensus on its diagnosis or classification. This survey-based study aimed to analyze the differential opinions of colorectal surgeons and radiation oncologists regarding the definition and treatment of OMD from the colorectal primary. Materials and Methods A total of 141 participants were included in this study, consisting of 63 radiation oncologists (44.7%) a

2
Article|1 citations·2015
Treatment outcome of hepatic re-irradiation in patients with hepatocellular carcinoma
설승원, 유정일, 박희철, 임도훈, 오동렬, 노재명, 조원경, 백승운

Purpose: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. Materials and Methods: Between 1998 and 2011, 45 patients received hepatic re-irradiation with high dose 3D-CRT in Samsung Medical Center. After excluding two ineligible patients, 43 patients were retrospectively reviewed. RT was delivered with palliative or salvage intent, and equivalent dose of 2 Gy fractions for α/β =

3
Article|0 citations·2016
Immunomodulatory effect of captopril and local irradiation on myeloid-derived suppressor cells
조원경, 신성원, 김신영, 홍장원, 최창훈, 박원, 노재명

Purpose This study is to investigate the effect of captopril when combined with irradiation. Materials and Methods 4T1 (mouse mammary carcinoma) cells were injected in the right hind leg of Balb/c mice. Mice were randomized to four groups; control (group 1), captopril-treated (group 2), irradiated (group 3), irradiated and captopril-treated concurrently (group 4). Captopril was administered by intraperitoneal injection (10 mg/kg) daily and irradiation was delivered on the tumor-bearing leg for 1

4
Article|0 citations·2024
금융상품 투자와 부당이득 ―대법원 2022. 10. 14. 선고 2018다244488 판결에 대하여―
조원경
증권법연구

해외장외시장에서 이루어지는 외국환거래인 FX 마진거래를 위해 투자자와 투자중개업자가 체결한 계약이 강행법규 위반으로 무효가 된 사안에서, 대상판결은, ① 투자자가 투자중개업자에게 지급한 위탁금을 투자중개업자가 ‘이득’으로 취득하였지만, ② 그 돈을 투자자의 지시에 따라 지출하여 정산하였으므로, 금전상 이득의 현존 추정이 번복되어, 투자중개업자에게 부당이득반환의무가 없다고 판단하였다. 금융투자계약을 체결하고 투자자가 투자를 위한 돈을 지급한 경우, 그 계약의 유형을 가리지 않고, 급부 이전, 즉 금전의 소유권이 이전됨으로써 투자자의 계약 상대방은 급부 상당의 이득을 취득한다. 이는 투자중개업자 등이 가지는 위탁금에 대한 지배관리 및 운용 권한 보유 여부와 무관하며, 그와 같은 권한을 보유하고 있지 않더라도 ‘실질적 이득’을 취득하였다고 볼 수 있는지 따질 필요가 없다고 봄이 타당하다. 대상판결 사안과 같은 투자중개계약에서 투자중개업자가 투자자의 지시에 따른 위탁금을 소비한 경우에는 ①

5
Article|0 citations·2025
재판중계와 초상권 침해 –미국법리와의 비교법적 고찰을 중심으로-대법원 2025. 2. 27. 선고 2023다233895 판결에 대한 평석-
조원경

피사체의 자발적 의사에 의하지 않고 얼굴이 드러나는 영상 또는 사진을 게재하는 행위를 할 경우 손해배상책임을 지는가는 명예훼손만큼이나 중요한 쟁점이 되었다. 대상판결은, 형사사건 대법원 공개변론의 재판중계 및 변론동영상의 법원 홈페이지 게시가 초상권 침해로서 불법행위에 해당하지 않는다고 판단하였다. 우리나라 판례에 의하면, ‘자신의 자발적 의사에 의하지 않은 얼굴이 드러나는 영상 또는 사진을 게재하는 행위’는 ‘초상권’이라는 별도의 인격권을 침해하는 행위로서 불법행위를 구성한다. 다만, 최종적인 위법성 판단을 위해서는 이익형량을 하여야 한다. 그런데 대법원의 이익형량 판단요소에 관한 판시는 다소 모호하고 추상적이다. 초상권 침해와 관련한 분쟁이 늘어날 것으로 예상되므로 좀더 명확한 위법성 판단기준을 세우는 것이 필요하고 바람직하며 그 기준 마련에 미국 법리가 시사점을 제공할 수 있다. 미국에서는 초상권 보호의 취지가 ‘원하지 않는 사적 공간에서의 사생활 공개’를 막는 데 있음을 분명

6
Article|0 citations·2023
Complete genome sequence of a novel soybean mosaic virus isolated from soybean seeds in Korea
신유섭, 박태선, 박지수, 민동주, 김예영, 박상민, 이수헌, 김상민, 이봉춘, 조원경, 홍진성

Soybean mosaic virus (SMV), a member of the genus Potyvirus, primarily damages soybeans. Although most SMV strains do not infect Solanaceae plants, an SMV isolate obtained from soybean seeds (SMV-Gm) was confirmed to induce systemic infection in Nicotiana benthamiana. Its complete genome sequence was determined using reverse transcription (RT)- PCR and cloning, showing that it comprises 9588 nucleotides, with a GC content of 41.65% and a single large polyprotein, consistent with the typical SMV

7
Article|0 citations·2023
Metastasis-Directed Local Therapy of Hepatic Oligometastasis from Colorectal Cancer and Future Perspective in Radiation Therapy
유규상, 임채홍, 조원경, 정재욱, 지의규, 조현민, 엄준원, 안용찬, 이종훈

Introduction of the concept for oligometastasis led to wide application of metastasis-directed local ablative therapies for metastatic colorectal cancer (CRC). By application of the metastasis-directed local ablative therapies including surgical resection, radiofrequency ablation (RFA), and stereotactic ablative body radiotherapy (SABR), the survival outcomes of patients with metastatic CRC have improved. The liver is the most common distant metastatic site in CRC patients, and recently various

8
Article|0 citations·2025
Significance of HPV status on tumor response and treatment outcomes in endocervical adenocarcinoma treated with definitive chemoradiotherapy: a retrospective study
Jong Yun Baek, Hyun-Soo Kim, 조원경, 김병기, Jeong-Won Lee, 최철훈, 김태중, 이유영, 박원

Objective: We aimed to compare tumor response and treatment outcomes between human papillomavirus (HPV)-associated (HPVA) and HPV-independent (HPVI) endocervical adenocarcinomas (ADCs) treated with definitive concurrent chemoradiotherapy (CCRT) and to identify prognostic factors. Methods: We conducted a retrospective review of 40 patients with endocervical ADCs treated with definitive CCRT (stages I–IVA) between 2011 and 2022. Based on pathological review the cases were categorized as HPVA or HP

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