Woo Hyuk Song

Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy. We report two cases of amiodarone-induced TdP shortly after administration of a low dose of oral amiodarone, in the absence of predisposing factors.

Our data demonstrated that cilostazol treatment in addition to conventional anti-platelet therapy provides more effective suppression of platelet P-selectin expression in patients with relatively high platelet activity.

In Korea, the prevalence of hypertension was similar to that in the western countries, but the awareness of hypertension was much lower compared with western countries. The prevalence of hypertension was higher in the snorer group, so more research on the correlation between the two conditions should be advanced in the future.

ClinicalTrials.gov Identifier: NCT03494270.

To evaluate the feasibility and usefulness of transthoracic Doppler echocardiography (TTDE) as a non-invasive method in recording distal anterior descending (LAD) coronary flow velocity, we compared coronary flow reserve (CFR) measured by TTDE with measurements by intracoronary Doppler wire (ICDW). Twenty-one patients without LAD stenosis were studied. ICDW performed at baseline and after intracoronary injection of 18 microg adenosine. TTDE was performed at baseline and after intravenous adenosi

BACKGROUND: Although accumulating evidence suggests a more extensive reduction of low-density lipoprotein cholesterol (LDL-C), it is unclear whether a higher statin dose is more effective and cost-effective in the Asian population. This study compared the efficacy, safety, and cost-effectiveness of atorvastatin 20 and 10 mg in high-risk Asian patients with hypercholesterolemia. METHODS: A 12-week, open-label, parallel, multicenter, Phase IV randomized controlled trial was conducted at ten hospit

Background and Objectives:Myocardial infarction in young age is an uncommon condition and has few risk factors than old aged group. Hyperhomocysteinemia, which is an independent risk factor for vascular disease, is associated with myocardial infarction (MI. Therefore, we evaluate that hyperhomocysteinemia is associated with myocardial infaction in young age. Materials and Methods:A total 64 patients (normal control 23 (young:old 13:10 mean age 54.2±13.8, M.I 41 (young:old=13:28 mean age 53.9±14.

Hospital PCI volume was not found to be an independent predictor of in-hospital clinical outcomes in patients with AMI included in the 2014 K-PCI registry.

연구목적： D형 인격은 국내에서는 아직 생소하며, 심혈관 질환을 비롯한 다양한 질환과의 관련성, 그리고 그 질환에 대한 예측인자로서의 가능성 등에 대해 아직까지 연구된 바가 거의 없다. 그러나, 기존 외국의 연구 결과들은 D형 인격이 심혈관 질환의 발병이나 경과에 중요한 예측인자가 될 수 있음을 보여 주었으며, 현재에도 관련 연구결과가 지속적으로 보고되고 있어 국내에서도 관련 연구가 요구되는 상황이다. 이에 본 저자들은 예비연구를 통해 D형 인격의 검사 도구인 DS14를 번안하고 이에 대한 신뢰도와 타당도를 검증함으로써, D형 인격 평가 척도의 표준화된 기준을 제시하고자 본 연구를 진행하였다. 방 법： 1차 조사에서는 총 17문항으로 구성된 DS14의 예비 척도를 국문으로 번역하여, 서울 및 경기도 안산지역에서 무작위 표집한 심혈관 질환이 없는 정상인 372명에게 작성하도록 하였다. 예비척도에서 척도화가 가능한 문항을 추출하여 14문항의 DS14를 완성하고, 그 신뢰도를 알아보았다.

This is a report of Brugada-like ST-segment abnormalities related to acute myocarditis associated with hematologic disorders. Electrocardiographic (ECG) pattern of ST-segment elevation in the right precordial leads mimicking Brugada syndrome may relate to pathological abnormalities due to hematologic disorders that may have genetic, infective, or inflammatory origins. We describe two cases of myocardial involvement of hemotologic disorders, manifested with Brugada-like ECG findings.

Background and ObjectivesChronic atrial fibrillation (AF) causes atrial enlargement and impairs cardiac function.It is known that restoration of sinus rhythm reduces left atrial size and improves left ventricular ejection fraction (EF).However, it's unclear whether the restoration of sinus rhythm is more beneficial than controlling the ventricular rate.This study was designed to compare the effects of two treatment strategies on structural and functional changes of the heart in patients with AF.

Objective: The aim of this study was to evaluate under target rates of low-density lipoproteincholesterol (LDL-C) in Korean patients with stable coronary artery disease (CAD) or an acute coronary syndrome (ACS) in real world practice. Methods: Dyslipidemia International Study II was an international observational study of patients with stable CAD or an ACS. Lipid profiles and use of lipid-lowering therapy (LLT) were documented at enrollment, and for the ACS cohort, 4 months follow-up was recomme

[This corrects the article DOI: 10.1371/journal.pone.0245481.].