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Woo-suk Lee

Yonsei University · Medicine

About the Lab

Professor Woo-suk Lee's research lab focuses on regenerative medicine and orthopedic surgery, particularly investigating the clinical efficacy and safety of mesenchymal stem cell therapy for osteoarthritis. The lab also explores the role of nutritional factors—such as vitamin D—on post-surgical recovery following total knee arthroplasty. Additionally, the lab contributes to biomedical engineering through the development of smart home automation systems that integrate wireless protocols like ZigBee and KNX for healthcare applications.

mesenchymal stem cellstotal knee arthroplastyvitamin DZigBee-KNX gatewayregenerative medicine

Research Overview

Papers
159
Total Citations
2,755
Papers (5y)
26
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
26total
2022
2023
2024
2025
2026
Citations per year (5y)
270total
20222023202420252026

Selected Papers

15
1
Article|492 citations·2019
Intra-Articular Injection of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase IIb, Randomized, Placebo-Controlled Clinical Trial
Woo-Suk Lee, Hwan Jin Kim, Kang‐Il Kim, Gi Beom Kim, Wook Jin
SJR Q1Stem Cells Translational MedicineOA

Mesenchymal stem cells (MSCs) have been the focus of an emerging treatment for osteoarthritis. However, few studies reported about outcomes of an intra-articular injection of autologous adipose-derived mesenchymal stem cells (AD-MSCs). This study aimed to assess the efficacy and safety of a single intra-articular injection of AD-MSCs for patients with knee osteoarthritis. It was a prospective double-blinded, randomized controlled, phase IIb clinical trial. AD-MSCs were administered for 12 patien

GeneticsMedicine
2
Review|105 citations·2012
The Incidence of Pulmonary Embolism and Deep Vein Thrombosis After Knee Arthroplasty in Asians Remains Low: A Meta-analysis
Woo-Suk Lee, Kang‐Il Kim, Han-Jun Lee, Hee-Soo Kyung, Seung-Suk Seo
SJR Q1Clinical Orthopaedics and Related ResearchOA

The incidence of symptomatic PE and DVT after TKA without prophylaxis is low in Asian countries and has not changed over time, despite Westernizing lifestyles and an aging populace. Further investigation with large randomized studies is necessary to confirm our findings and identify risk factors predisposing to DVT.

Internal MedicineMedicine
3
Article|51 citations·2016
Vitamin D deficiency adversely affects early post-operative functional outcomes after total knee arthroplasty
Keun-Young Shin, Kwan Kyu Park, Seong-Hwan Moon, Ick Hwan Yang, Ho-June Choi, Woo-Suk Lee
SJR Q1Knee Surgery Sports Traumatology ArthroscopyOA

PURPOSE: Vitamin D has received considerable attention in recent years owing to the increasing evidence of its importance in muscle function and physical performance. The present study attempted to determine whether patients with low serum vitamin D levels had impairment in early functional outcomes following total knee arthroplasty (TKA). METHODS: (25(OH)D) levels <12 ng/mL; (2) vitamin D non-deficient group, serum 25(OH)D levels ≥12 ng/mL. American Knee Society Score (KSS) and four other perfo

Pathology and Forensic MedicineMedicine
4
Article|47 citations·2005
The sensing behavior of SnO2-based thick-film gas sensors at a low concentration of chemical agent simulants
Woo-Suk Lee, Soo Chool Lee, Soo Jae Lee, Duk Dong Lee, Jeung Soo Huh, Hee Kwon Jun, Jae Chang Kim
SJR Q1Sensors and Actuators B Chemical
Electrical and Electronic EngineeringEngineering
5
Article|44 citations·2009
Implementation of a KNX-ZigBee gateway for home automation
Woo-Suk Lee, Seung Ho Hong

The demand for wireless technology in home automation systems has recently been increasing due to several advantages such as installation cost reduction, easy placement, easy extension, aesthetic benefits, and mobile device connectivity. Among the many wireless technologies available, ZigBee is one of the most useful for home automation. A wireless home networking system can be configured using ZigBee alone. However, compatibility with conventional networking systems based on wired media is not

Electrical and Electronic EngineeringEngineering
6
Article|26 citations·2008
KNX &#x2014; ZigBee gateway for home automation
Woo-Suk Lee, Seung Ho Hong

The demand for wireless technology in home automation systems has recently been increasing due to several advantages such as installation cost reduction, easy placement, easy extension, aesthetic benefits, and mobile device connectivity. Among the many wireless technologies, ZigBee is one of the most useful for home automation; a wireless home networking system can be configured using ZigBee alone. Compatibility with conventional home networking systems that are based on wired media, however, is

Electrical and Electronic EngineeringEngineering
7
Article|25 citations·2020
Cigarette smoking and knee osteoarthritis in the elderly: Data from the Korean National Health and Nutritional Examination Survey
Hyuck Min Kwon, Ick-Hwan Yang, Kwan Kyu Park, Byung Woo Cho, Junwoo Byun, Woo-Suk Lee
SJR Q1Experimental GerontologyOA
RheumatologyMedicine
8
Article|23 citations·2024
Risk factors for early septic failure after two-stage exchange total knee arthroplasty for treatment of periprosthetic joint infection
Woo-Suk Lee, Kwan Kyu Park, Byung Woo Cho, Jun Young Park, I. Y. Kim, Hyuck Min Kwon
SJR Q1Journal of Orthopaedics and TraumatologyOA

BACKGROUND: The cause of early septic failure after two-stage exchange revision total knee arthroplasty (TKA) for chronic periprosthetic joint infection (PJI) and the factors affecting it are not well known. The purpose of this study was to determine the surgical outcomes and the risk factors for early septic failure after two-stage revision TKA for chronic PJI. METHODS: We identified a total of 246 adult patients who met the Musculoskeletal Infection Society (MSIS) diagnostic criteria for chron

SurgeryMedicine
9
Article|18 citations·2020
Anatomical tibial component is related to more medial tibial stress shielding after total knee arthroplasty in Korean patients
Byung Woo Cho, Hyuck Min Kwon, Yong Jae Hong, Kwan Kyu Park, Ick Hwan Yang, Woo-Suk Lee
SJR Q1Knee Surgery Sports Traumatology ArthroscopyOA

PURPOSE: This study aimed to investigate stress shielding of anatomical tibial components (ATCs) in comparison to conventional symmetric tibial components (STCs) in Korean patients which may be related to medial tibial bone loss. METHOD: 78 knees in 59 patients with ATCs (Persona™) and 74 knees in 58 patients with STCs (NexGen LPS-Flex™) were retrospectively reviewed. Radiographic parameters and clinical outcomes in both groups were compared. Logistic regression analysis was performed to identif

SurgeryMedicine
10
Review|17 citations·2021
Method Categorization of Stem Cell Therapy for Degenerative Osteoarthritis of the Knee: A Review
Jae Sun Lee, Dong Woo Shim, Kyung-Yil Kang, Dong‐Sik Chae, Woo-Suk Lee
SJR Q1International Journal of Molecular SciencesOA

Current clinical applications of mesenchymal stem cell therapy for osteoarthritis lack consistency because there are no established criteria for clinical processes. We aimed to systematically organize stem cell treatment methods by reviewing the literature. The treatment methods used in 27 clinical trials were examined and reviewed. The clinical processes were separated into seven categories: cell donor, cell source, cell preparation, delivery methods, lesion preparation, concomitant procedures,

GeneticsMedicine
11
Article|11 citations·2014
When they are not listening: Harvesting power from idle sensors in embedded systems
Woo-Suk Lee, Hrishikesh Jayakumar, Vijay Raghunathan

Ambient energy harvesting is a well-known technique in wireless sensing systems. To minimize energy consumption, such systems are typically designed to be heavily duty-cycled with long idle times and are characteristically lightweight in computation. Often, these systems contain a dedicated energy harvesting transducer that is independent of the sensing sub-system. As a result, any output energy from the sensor ends up being unused (and hence, lost) when the system is in idle state. This work pr

Electrical and Electronic EngineeringEngineering
12
Article|10 citations·2017
N-Dodecane Autothermal Reforming Properties of Ni-Al Based Catalysts Prepared by Various Methods
Woo-Suk Lee, Dong Geon Ju, Suk Yong Jung, Soo Chool Lee, Dong Su Ha, Byng Wook Hwang, Jae Chang Kim
SJR Q2Topics in Catalysis
Materials ChemistryMaterials Science
13
Article|10 citations·2022
Acetabular labral tear is associated with high pelvic incidence with or without femoroacetabular impingement morphology
Hyuck Min Kwon, Byung Woo Cho, Sung Jun Kim, Ick-Hwan Yang, Kwan Kyu Park, Nak‐Hoon Son, Woo-Suk Lee
SJR Q1Knee Surgery Sports Traumatology ArthroscopyOA

PURPOSE: The aim of this study was to investigate the association between pelvic sagittal parameters and acetabular labral tears. METHODS: Three-hundred and sixty-five patients (449 hips) who underwent magnetic resonance imaging (MRI) or magnetic resonance arthrogram (MRA) for hip pain were enrolled in this study. Pelvic sagittal parameters, including the pelvic incidence, pelvic tilt, and sacral slope, were measured with a standing lumbosacral lateral radiograph. All subjects were divided into

SurgeryMedicine
14
Article|10 citations·2014
UP-link: An ultra-low power implantable wireless system for long-term ambulatory urodynamics
Woo-Suk Lee, Albert Kim, Babak Ziaie, Vijay Raghunathan, Charles R. Powell

Monitoring of bladder pressure, known as cystometry, is a key diagnostic tool in urodynamic studies of patients that exhibit lower urinary tract symptoms. Over the past few years, there has been an increased interest in ambulatory urodynamics due to the increased convenience and more realistic monitoring environment. This paper presents an ultra-low power implantable wireless platform, UP-Link, for long-term ambulatory bladder pressure monitoring. The proposed platform, which is built using off-

UrologyMedicine
15
Article|6 citations·2021
The effect of hamstring tightness on intraoperative extension gap in posterior stabilized total knee arthroplasty
Byung Woo Cho, Hyuck Min Kwon, Koo Yeon Lee, Kwan Kyu Park, Ick Hwan Yang, Woo-Suk Lee
SJR Q1Scientific ReportsOA

This study aimed to determine the factors related to intraoperative extension gap (EG) in patients who underwent posterior-stabilized total knee arthroplasty (TKA). A total of 106 TKAs in 84 patients were retrospectively reviewed. Only patients who underwent the same method of bone resection were included consecutively. Bilateral popliteal angle (BPA) was used as an indicator of hamstring tightness. EG and extension space angle were measured using an offset type tensor. The associations between

SurgeryMedicine

Research Areas

SurgeryElectrical and Electronic EngineeringRheumatologyOrthopedics and Sports MedicineBiomedical EngineeringEpidemiology

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