Yeon-ju Lee

Halloysite nanotube (HNT)-based supramolecular complexes are synthesized and evaluated with respect to their cytotoxicity and effects on cellular structures. As HNTs are water-insoluble, DNA is applied for wrapping the surface of HNTs to enhance their water-dispersibility. To investigate the potential of DNA-wrapped HNTs (HD) as a promising drug delivery carrier, doxorubicin (DOX) is introduced as a model anticancer agent and loaded onto HD. The DOX-loaded, DNA-wrapped HNTs (HDD) show sustained

With the increasing interest in the biological applications of carbon nanotubes, their interactions in the biological interphase and their general cytotoxicity have become major issues. In spite of their salient properties, major hurdles still exist for their use in biological applications, due to their main characteristics, including their hydrophobic surfaces and tendency to aggregate, as well as their unknown interactions in the cellular interphase. In this Research News, these characteristic

The particle size and surface properties of gold nanoparticles are critical factors for the interactions between nanoparticles and cells. To produce noncytotoxic gold nanoparticles, a straightforward method for the synthesis of gold nanoparticles designed involving the reduction and stabilization by a protein such as a lysozyme in conjunction with microwave irradiation. The cooperative combination of a lysozyme with a high affinity for metal ions and the microwave irradiation allowed to form bio

This study was aimed at investigating the possible effects of phytoceramide (Pcer) on learning and memory and their underlying mechanisms. Phytoceramide was orally administered to ICR mice for 7 days. Memory performances were assessed using the passive avoidance test and Y-maze task. The expressions of phosphorylated cAMP response element binding protein (pCREB),brain-derived neurotrophic factor (BDNF) were measured with immunoblot. The incorporation of 5-bromo-2-deoxyuridine (BrdU)in hippocampa

Abstract ZnO nanoparticles (NPs) of 4–5 nm, widely adopted as an electron transport layer (ETL) in quantum dot light emitting diodes (QD-LEDs), were synthesized using the solution-precipitation process. It is notable that synthesized ZnO NPs are highly degenerate intrinsic semiconductors and their donor concentration can be increased up to N D = 6.9 × 10 21 cm –3 by annealing at 140 °C in air. An optical bandgap increase of as large as 0.16–0.33 eV by degeneracy is explained well by the Burstein

In this study, NiS/graphene nanocomposites were synthesized by simple heat treatment method of three graphene materials (graphene oxide (GO), reduced graphene oxide (rGO) and nitrogen-doped graphene oxide (N-rGO)) and NiS precursor. The morphology and crystal structure of NiS/graphene nanocomposites were characterized using field emission scanning electron microscope (FE-SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and Raman spectroscopy. Electrochemical properties were

Poly(4-hydroxystyrene) block copolymers containing maleic acid groups in one block were prepared through nitroxide mediated polymerization and their thin films with or without BaTiO3 nanoparticles were evaluated as a solution-processable dielectric materials. Poly(4-hydroxystyrene-co-maleic acid)-block-poly(4-hydroxystyrene) was successfully prepared through the hydrolysis of poly(4-acetoxystyrene-co-maleic anhydride)-block-poly(4-acetoxystyrene), as evidenced by GC, GPC, FT-IR and NMR. Through

The cytotoxicity and cellular uptake of carbon nanotubes (CNTs) has recently attracted considerable interest because of the issue of biosphere-nanomaterial interactions. The biocompatibility of CNTs is determined by the metal impurities in the CNTs, the size of the CNTs and the CNT dispersion states; in particular, the type of surface modifications on the CNTs affects how they interact with cells and determines their cytotoxicity and cellular uptake. In this study, biocompatible single-walled ca

BACKGROUND: Abdominal and pelvic computed tomography (APCT) has become the preferred means for the initial evaluation of blunt trauma patients. However, computed tomography examination has some disadvantages, such as radiation exposure, the requirement for intravenous iodinated contrast medium, high cost, and time. We aimed to develop a nomogram to predict the need for APCT scanning after the primary survey of blunt trauma patients. MATERIALS AND METHODS: We conducted a retrospective observation

The object of this work is to establish an electrochemical noise(EN) measurement technique combined with a direct current potential drop(DCPD) method for monitoring of localized corrosion cracking of nickel-based alloy, and to analyze its mechanism. The electrochemical current and potential noises were measured under various conditions of applied stress to a compact tension specimen in a simulated primary water chemistry of a pressurized water reactor. The amplitude and frequency of the EN signa