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Yesheong Park

Seoul National University · Medicine

About the Lab

Professor Yesheong Park's research lab specializes in surgical oncology and minimally invasive surgical techniques, with a focus on improving outcomes in gastrointestinal and breast cancers. The lab investigates the impact of surgical approaches—such as laparoscopic and robotic procedures—on patient prognosis, particularly in early-stage cancers like gallbladder, hepatocellular carcinoma, and thyroid cancer. Key research directions include optimizing surgical strategies based on tumor biology (e.g., ER status in breast cancer), evaluating ablation versus resection in small liver tumors, and assessing the influence of patient factors like BMI and postoperative complications such as pancreatic fistula. The lab emphasizes evidence-based surgical decision-making through retrospective cohort and propensity-matched analyses in tertiary care settings.

surgical oncologyminimally invasive surgeryoncologic outcomespancreatic fistulaliver cancer

Research Overview

Papers
36
Total Citations
151
Papers (5y)
34
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
34total
2021
2022
2023
2024
2025
Citations per year (5y)
150total
20212022202320242025

Selected Papers

15
1
Article|30 citations·2021
Effect of Estrogen Receptor Expression Level and Hormonal Therapy on Prognosis of Early Breast Cancer
Kyung-Hwak Yoon, Yeshong Park, Eunyoung Kang, Eun‐Kyu Kim, Jee Hyun Kim, Se Hyun Kim, Koung Jin Suh, Sun Mi Kim, Mijung Jang, Bo La Yun, So Yeon Park, Hee-Chul Shin
SJR Q1Cancer Research and TreatmentOA

PURPOSE: Estrogen receptor (ER) expression in breast cancer plays an essential role in carcinogenesis and disease progression. Recently, tumors with low level (1%-10%) of ER expression have been separately defined as ER low positive (ERlow). It is suggested that ERlow tumors might be morphologically and behaviorally different from tumors with high ER expression (ERhigh). MATERIALS AND METHODS: Retrospective analysis of a prospective cohort database was performed. Patients who underwent curative

GeneticsBiochemistry, Genetics and Molecular Biology
2
Article|17 citations·2023
Prognostic Effect of Liver Resection in Extended Cholecystectomy for T2 Gallbladder Cancer Revisited
Yeshong Park, Jun Suh Lee, Boram Lee, Yeongsoo Jo, Eun Hye Lee, MeeYoung Kang, Wooil Kwon, Chang-Sup Lim, Jin‐Young Jang, Ho‐Seong Han, Yoo‐Seok Yoon
SJR Q1Annals of Surgery

OBJECTIVE: This study aimed to evaluate the effect of liver resection on the prognosis of T2 gallbladder cancer (GBC). BACKGROUND: Although extended cholecystectomy [lymph node dissection (LND) + liver resection] is recommended for T2 GBC, recent studies have shown that liver resection does not improve survival outcomes relative to LND alone. METHODS: Patients with pT2 GBC who underwent extended cholecystectomy as an initial procedure and did not reoperation after cholecystectomy at 3 tertiary r

SurgeryMedicine
3
Article|16 citations·2023
Validation of the Anatomical and Biological Definitions of Borderline Resectable Pancreatic Cancer According to the 2017 International Consensus for Survival and Recurrence in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Upfront Surgery
Boram Lee, Yoo‐Seok Yoon, MeeYoung Kang, Yeshong Park, Eun Hye Lee, Yeongsoo Jo, Jun Suh Lee, Hae Won Lee, Jai Young Cho, Ho‐Seong Han
SJR Q1Annals of Surgical Oncology
OncologyMedicine
4
Article|11 citations·2021
Safety and effectiveness of reduced-port laparoscopic sleeve gastrectomy in Asian morbidly obese patients
Yeshong Park, Young Suk Park, Sang Jun Lee, So Hyun Kang, Eun‐Ju Lee, Sang-Hoon Ahn, Yun‐Suhk Suh, Do Joong Park, Hyung‐Ho Kim, Do Joong Park, Hyung‐Ho Kim
SJR Q1Scientific ReportsOA

Laparoscopic sleeve gastrectomy is the most frequently performed surgical intervention in patients with morbid obesity. Single-port sleeve gastrectomy (SPSG) and reduced-port sleeve gastrectomy (RPSG) are increasingly reported in the literature. This study compared the short-term outcomes of SPSG, RPSG, and conventional laparoscopic sleeve gastrectomy (CLSG). This is a single-center retrospective study of 238 morbidly obese patients, of whom 148 (62.2%) patients completed follow-up one year afte

SurgeryMedicine
5
Article|10 citations·2023
Comparative Study of Long-Term Outcomes of Laparoscopic Liver Resection versus Radiofrequency Ablation for Single Small Hepatocellular Carcinoma Located in Left Lateral Segments of the Liver
MeeYoung Kang, Jai Young Cho, Ho‐Seong Han, Yoo‐Seok Yoon, Hae Won Lee, Boram Lee, Yeshong Park, Jinju Kim, Chang Jin Yoon
SJR Q2MedicinaOA

Background and Objectives: Laparoscopic liver resection (LLR) is now widely recognized as the primary surgical option for hepatocellular carcinomas (HCC) smaller than 3 cm located in the left lateral segment of the liver. Nevertheless, there is a scarcity of studies comparing laparoscopic liver resection with radiofrequency ablation (RFA) in these cases. Materials and Methods: We retrospectively compared the short- and long-term outcomes of Child–Pugh class A patients who underwent LLR (n = 36)

HepatologyMedicine
6
Article|8 citations·2023
Effect of body habitus on surgical outcomes following bilateral axillo-breast approach robotic thyroidectomy: a retrospective cohort study
Yeshong Park, Hyeong Won Yu, Ja Kyung Lee, Jee‐Hye Choi, Woochul Kim, JungHak Kwak, Su‐jin Kim, Young Jun Chai, Hyunsuk Suh, June Young Choi, Kyu Eun Lee
SJR Q1International Journal of SurgeryOA

INTRODUCTION: BMI has been shown to predict perioperative outcomes in patients undergoing surgery. Most studies assessing the role of body habitus in thyroid surgery have focused on open surgery, with few studies assessing patients undergoing robotic surgery. The present study evaluated the effects of BMI on surgical outcomes in patients undergoing bilateral axillo-breast approach (BABA) robotic thyroidectomy. MATERIALS AND METHODS: This study included patients who underwent BABA robotic thyroid

SurgeryMedicine
7
Article|5 citations·2023
Impact of Drain Position on Drain Fluid Amylase, Fluid Collection and Postoperative Pancreatic Fistula after Distal Pancreatectomy
Jun Suh Lee, Yoo‐Seok Yoon, Ho‐Seong Han, Jai Young Cho, Hae‐Won Lee, Boram Lee, Yeongsoo Jo, Mee-Young Kang, Eun Hye Lee, Yeshong Park
SJR Q1World Journal of Surgery

BACKGROUND: The current definition for postoperative pancreatic fistula (POPF) is based on the drain fluid amylase (DFA), and drains must be positioned adequately. We investigated the impact of DFA level, drain position and fluid collection after distal pancreatectomy (DP). METHODS: We performed a retrospective study of 516 patients who underwent DP between June 2004 and December 2018. Patients were excluded if DP was not main procedure, DFA was not measured, postoperative computed tomography (C

OncologyMedicine
8
Article|5 citations·2025
Treatment strategies for solitary hepatocellular carcinoma: comparative outcomes of radiofrequency ablation vs. laparoscopic liver resection based on tumor location
Boram Lee, Ho‐Seong Han, Yoo‐Seok Yoon, Jai Young Cho, Hae Won Lee, Jae‐Hwan Lee, Yeshong Park, MeeYoung Kang, Jinju Kim
SJR Q1Surgical Endoscopy
HepatologyMedicine
9
Review|5 citations·2023
The value of analyzing textbook outcomes after laparoscopic hepatectomy—a narrative review
Mizelle D’Silva, Jai Young Cho, Ho‐Seong Han, Yoo‐Seok Yoon, Hae Won Lee, Jun Suh Lee, Boram Lee, Yeongsoo Jo, Eun Hye Lee, Mee-Young Kang, Yeshong Park
SJR Q2Translational Cancer ResearchOA

At present, TO only consider surgeon-related factors. However, it is important to include the patient's perspective when defining TO. Although TO were recently applied to laparoscopic hepatectomy, there is still a need to further evaluate their application in this setting. Achieving TO was shown to have a positive impact on long-term outcomes and this needs to be studied for different liver resection procedures.

Pulmonary and Respiratory MedicineMedicine
10
Article|4 citations·2023
Pyogenic liver abscess secondary to gastric perforation of an ingested toothpick: A case report
Yeshong Park, Ho‐Seong Han, Yoo-Seok Yoon, Jai Young Cho, Boram Lee, MeeYoung Kang, Jinju Kim, Hae Won Lee
World Journal of Clinical CasesOA

BACKGROUND: Liver abscess due to foreign body-induced gastrointestinal tract perforation is a rare event that could be misdiagnosed due to low suspicion. Less than 100 cases have been reported to date. CASE SUMMARY: We report a case of a 53-year old female patient with pyogenic liver abscess secondary to ingestion of a toothpick with penetration through the lesser curvature of the stomach. The patient presented with persistent epigastric pain. Abdominal computed tomography demonstrated the prese

Radiology, Nuclear Medicine and ImagingMedicine
11
Article|4 citations·2025
“Obesity Paradox” as a new insight from long-term survivors in pancreatic cancer patients
Boram Lee, Ho‐Seong Han, Yoo Seok Yoon, Yeshong Park, MeeYoung Kang, Jinju Kim
SJR Q1HPB
OncologyMedicine
12
Article|4 citations·2022
Development and Validation of a Difficulty Scoring System for Laparoscopic Liver Resection to Treat Hepatolithiasis
Yeongsoo Jo, Jai Young Cho, Ho‐Seong Han, Yoo‐Seok Yoon, Hae Won Lee, Jun Suh Lee, Boram Lee, Eun Hye Lee, Yeshong Park, MeeYoung Kang, Jung-Hyun Lee
SJR Q2MedicinaOA

Background and Objectives: A difficulty scoring system was previously developed to assess the difficulty of laparoscopic liver resection (LLR) for liver tumors; however, we need another system for hepatolithiasis. Therefore, we developed a novel difficulty scoring system (nDSS) and validated its use for predicting postoperative outcomes. Materials and Methods: This was a retrospective study. We used clinical data of 123 patients who underwent LLR for hepatolithiasis between 2003 and 2021. We ana

HepatologyMedicine
13
Article|3 citations·2023
Salvage Hepatectomy for Recurrent Hepatocellular Carcinoma after Radiofrequency Ablation: A Retrospective Cohort Study with Propensity Score-Matched Analysis
Yeshong Park, Ho‐Seong Han, Yoo‐Seok Yoon, Chang Jin Yoon, Hae Won Lee, Boram Lee, MeeYoung Kang, Jinju Kim, Jai Young Cho
SJR Q1CancersOA

Background and Objectives: Although radiofrequency ablation (RFA) is a well-established locoregional treatment modality for hepatocellular carcinoma (HCC), the optimal strategy to handle local recurrence after ablation is still debated. This study aims to investigate the role of salvage hepatectomy (SH) as a rescue therapy for recurrent HCC after RFA. Materials and Methods: Between January 2004 and December 2020, 1161 patients were subject to surgical resection for HCC. Among them, 47 patients w

HepatologyMedicine
14
Article|3 citations·2024
Role of Minimally Invasive Reoperation for Postoperatively Diagnosed T2 Gallbladder Cancer: Multicenter Retrospective Cohort Study
Yeshong Park, Sae Byeol Choi, Boram Lee, Ho‐Seong Han, Chi‐Young Jeong, Chang Moo Kang, Dae Wook Hwang, Wan‐Joon Kim, Yoo‐Seok Yoon
SJR Q1Journal of the American College of Surgeons

BACKGROUND: Although T2 gallbladder cancer (GBC) incidentally diagnosed after cholecystectomy requires additional resection, the surgical approaches are technically difficult due to inflammatory adhesion or fibrosis around the hepatoduodenal ligament and gallbladder bed. In this study, we sought to compare the surgical and oncologic outcomes of open and minimally invasive reoperation for postoperatively diagnosed T2 GBC. STUDY DESIGN: Patients who underwent open (110) and laparoscopic (38) reope

SurgeryMedicine
15
Article|3 citations·2024
Achieving Textbook Outcomes after Laparoscopic Resection in Posterosuperior Segments of the Liver: The Impact of the Learning Curve
Mizelle D’Silva, Jai Young Cho, Ho‐Seong Han, Yoo‐Seok Yoon, Hae-Won Lee, Boram Lee, Mee-Young Kang, Yeshong Park, Jinju Kim
SJR Q1CancersOA

Achieving textbook outcomes (TOs) improves the short-term and long-term performance of a hospital. Our objective was to assess TOs in the laparoscopic liver resection (LLR) of tumors in the PS (posterosuperior) section of the liver and identify the impact of the learning curve. We conducted a retrospective cohort study analyzing patients who underwent LLR for lesions located in the PS segments. Patients were divided into a TO and no-TO group. TOs were defined as negative margins, no transfusion,

OncologyMedicine

Research Areas

SurgeryHepatologyOncologyGeneticsHematologyPulmonary and Respiratory Medicine

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