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Yi-Chan Kyung

Sungkyunkwan University · Medicine

About the Lab

Professor Yi-Chan Kyung's research lab focuses on pediatric allergic diseases, with a strong emphasis on understanding the environmental, dietary, and immunological factors influencing the development and management of atopic dermatitis, food allergies, and asthma in children and adolescents. The lab investigates the interplay between gut microbiota, early-life nutrition, and immune programming, as well as the impact of prenatal exposures—such as phthalates—on allergic sensitization. A key research direction involves evaluating the safety, feasibility, and long-term outcomes of oral immunotherapy for food allergies, particularly egg allergy. The lab also examines the mental health burden associated with chronic allergic conditions in adolescents, highlighting the need for integrated care approaches.

atopic dermatitisfood allergygut microbiomeoral immunotherapyadolescent mental health

Research Overview

Papers
37
Total Citations
151
Papers (5y)
20
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
20total
2021
2022
2023
2024
2025
Citations per year (5y)
67total
20212022202320242025

Selected Papers

15
1
Article|23 citations·2020
Health‐related behaviors and mental health states of South Korean adolescents with atopic dermatitis
Yechan Kyung, Ju Suk Lee, Jun Hwa Lee, Seon Hui Jo, Sung Hoon Kim
SJR Q1The Journal of Dermatology

Atopic dermatitis (AD) is a common chronic skin disease with a negative influence on adolescent mental health state. We aimed to identify the influencing factors for mental health in adolescents with AD. We used data from the 13th Korean Youth Risk Behavior Web-based Survey (KYRBS) conducted in 2017. KYRBS data were obtained from a stratified, multistage, clustered sample. Participants responded to the question "have you ever been diagnosed with AD by a doctor?" and several yes/no questions abou

DermatologyMedicine
2
Article|23 citations·2020
Association of atopic dermatitis with suicide risk among 788,411 adolescents
Yechan Kyung, Min Hwan Choi, Yoo Jung Jeon, Ju Suk Lee, Jun Hwa Lee, Seon Hui Jo, Sung Hoon Kim
SJR Q1Annals of Allergy Asthma & Immunology
DermatologyMedicine
3
Article|20 citations·2022
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants
Bora Lee, Hyein Jung, Su Kyung Kim, Mijeoung Kwon, Hyunmi Kim, Minyoung Jung, Yechan Kyung, Byung Eui Kim, Suk‐Joo Choi, Soo‐Young Oh, Sun‐Young Baek, Seonwoo Kim
SJR Q1Immune NetworkOA

We aimed to investigate associations of dietary diversity (DD) with gut microbial diversity and the development of hen's egg allergy (HEA) in infants. We enrolled 68 infants in a high-risk group and 32 infants in a control group based on a family history of allergic diseases. All infants were followed from birth until 12 months of age. We collected infant feeding data, and DD was defined using 3 measures: the World Health Organization definition of minimum DD, food group diversity, and food alle

PhysiologyMedicine
4
Article|15 citations·2021
Home-Based Up-Dosing in Build-Up Phase of Oral Immunotherapy of Egg Allergy Is Safe and Feasible in Real-World Practice
Hyein Jeong, Bora Lee, Sukyung Kim, Yechan Kyung, Minyoung Jung, Minji Kim, Ji Young Lee, Kevin Kim, Kangmo Ahn, Jihyun Kim
SJR Q1Allergy Asthma and Immunology ResearchOA

Oral immunotherapy (OIT) has emerged to build sustained unresponsiveness or tolerance in patients with egg allergy. However, it is important to increase compliance and ensure safety because OIT requires an extended period of time and has a risk of side effects like anaphylaxis. We aimed to show the feasibility and safety of OIT during the build-up phase using a home-based, up-dosing method in children with egg allergy. Sixteen patients aged 4 to 12 years with egg allergy were enrolled. Patients

Immunology and AllergyMedicine
5
Article|9 citations·2020
Evaluation of changing trend in depression, suicidal ideation, and suicide attempts among adolescents with asthma and identification of associated factors: 11-year national data analysis in 788,411 participants
Yechan Kyung, Young Joo Han, Ju Suk Lee, Jun Hwa Lee, Seon Hui Jo, Sung Hoon Kim
SJR Q2Journal of Asthma

Although the prevalence of asthma was similar every year, the prevalence of depression and suicidality among adolescents with asthma decreased. Nevertheless, clinical physicians should pay more attention to screen for depression and suicidality among adolescents with asthma, especially having associated factors.

Clinical PsychologyPsychology
6
Review|9 citations·2021
Effect of prenatal phthalate exposure on childhood atopic dermatitis: A systematic review and meta-analysis
Minyoung Jung, Min‐Ji Kim, Seonwoo Kim, Yechan Kyung, Minji Kim, Ji Young Lee, Hyein Jeong, Bora Lee, Jihyun Kim, Kangmo Ahn, Yong Mean Park
SJR Q2Allergy and Asthma Proceedings

Background: The association between prenatal exposure to phthalate and childhood atopic dermatitis (AD) has previously been investigated; however, the results are inconsistent. Objective: We aimed to perform a systematic review and meta-analysis of birth cohort studies to investigate whether prenatal exposure to phthalate increases the risk of developing AD in children. Methods: We performed an electronic search of medical literature data bases. Studies were critically appraised, and a meta-anal

Health, Toxicology and MutagenesisEnvironmental Science
7
Article|8 citations·2020
Influencing Factors for Influenza Vaccination among South Korean Adolescents with Asthma Based on a Nationwide Cross-Sectional Study
Yechan Kyung, Min Hwan Choi, Ju Suk Lee, Jun Hwa Lee, Seon Hui Jo, Sung Hoon Kim
SJR Q2International Archives of Allergy and Immunology

BACKGROUND: Influenza viral infection is a major public health problem with significant morbidity and mortality.Asthma is a risk factor for developing serious complications related to influenza infection. OBJECTIVE: We explored factors associated with influenza vaccination coverage among adolescents with asthma. METHODS: Data were obtained from 62,276 participants in the 13th Korean Youth Risk Behavior Web-Based Survey (KYRBS) conducted in 2017. KYRBS data were obtained from a stratified, multis

EpidemiologyMedicine
8
Article|7 citations·2021
Natural Course and Prognostic Factors of Immediate-Type Peanut Allergy in Children
Minyoung Jung, Hyein Jeong, Yechan Kyung, Su Kyung Kim, Ju Suk Lee, Minhwan Choi, Jung Yeon Shim, Layun Kim, Hojeong Won, Kyunga Kim, Jihyun Kim, Kangmo Ahn
SJR Q2International Archives of Allergy and Immunology

BACKGROUND: Predicting food allergy resolution is essential to minimize the number of restricted foods in children. However, there have been no studies on the natural history of peanut allergy (PA) in Korea. OBJECTIVE: This study aimed to evaluate the natural course and prognostic factors of immediate-type PA in children till the age of 10 years. METHODS: We retrospectively collected data of 122 children who developed PA before 60 months of age from 3 tertiary hospitals in Korea. Diagnosis and r

Immunology and AllergyMedicine
9
Article|6 citations·2024
Postpartum Maternal Anxiety Affects the Development of Food Allergy Through Dietary and Gut Microbial Diversity During Early Infancy
Hyunbin Cho, Jiwon Kim, Sukyung Kim, Hyein Jeong, Mijeoung Kwon, Hyun Mi Kim, Ji Sun Shim, Kyunga Kim, Ji Hyun Baek, Yechan Kyung, Suk‐Joo Choi, Soo‐Young Oh
SJR Q1Allergy Asthma and Immunology ResearchOA

Postpartum maternal anxiety, mediated by reduced DD and gut microbial diversity, may be a risk factor for the development of FA in infants during the first 2 years of life.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|6 citations·2014
A pediatric case of Brugada syndrome diagnosed by fever-provoked ventricular tachycardia
Geena Kim, Yechan Kyung, I‐Seok Kang, Jinyoung Song, June Huh, Young Keun On
Korean Journal of PediatricsOA

Brugada syndrome is a rare channelopathy associated with the SCN5A gene that causes fatal ventricular arrhythmias. This case of Brugada syndrome, in which ventricular tachycardia (VT) was provoked by high fever, is the first report in a Korean child. The boy had retinoblastoma of his left eye diagnosed at 16 months of age. After chemotherapy, he contracted a catheter-related infection with a high fever up to 41℃ leading to monomorphic VT. This was characterized as having right bundle branch bloc

Cardiology and Cardiovascular MedicineMedicine
11
Article|5 citations·2020
The effect of hidden female smoking on the relationship between smoking and cardiovascular disease
Sang Won Hwang, Hae Jeong Lee, Cheol Hong Kim, Sung Hoon Kim, Yechan Kyung, Sang Taek Lee, Ju Suk Lee
SJR Q2Cardiology JournalOA

In the current study, while ex-smoking status was significantly associated with CVD, current smoking status was not. Female ex-smoking status had a higher adjusted odds ratio for CVD than males compared to non-smoking status. An effect of hidden female smoking was also found on the association between smoking status and CVD in Korean adults.

PhysiologyMedicine
12
Article|4 citations·2023
Association of Sleep Duration and Weekend Catch-Up Sleep with Suicidal Ideation among Adolescents with Atopic Dermatitis
Dong Wan Kang, Sung Hoon Kim, Yechan Kyung, Hae Jeong Lee
SJR Q1Journal of Clinical MedicineOA

Atopic dermatitis (AD) is a prevalent allergic disease in children that often causes sleep disturbance and which is associated with diminished quality of life and heightened susceptibility to depression and suicidality. In this study, we investigate the relationship between weekend catch-up sleep (WCUS) and mental health in a sample of 71,434 adolescents with AD and 221,057 without AD using multivariate logistic regression analysis. We hypothesized that adolescents with AD experience shorter tot

DermatologyMedicine
13
Article|3 citations·2020
Three cases of oral immunotherapy for IgE-mediated egg allergy
Insung Kim, Bora Lee, Yechan Kyung, Minyoung Jung, Hea-Kyoung Yang, Minji Kim, Ji Young Lee, Jihyun Kim, Kangmo Ahn, Hyein Jeong
Allergy Asthma & Respiratory DiseaseOA
Immunology and AllergyMedicine
14
Article|2 citations·2015
Birth seasonality in Korean Prader-Willi syndrome with chromosome 15 microdeletion
Aram Yang, Yeon Hee Lee, Soon Young Nam, Yu Ju Jeong, Yechan Kyung, Rimm Huh, Jieun Lee, Younghee Kwun, Sung Yoon Cho, Dong‐Kyu Jin
SJR Q1Annals of Pediatric Endocrinology & MetabolismOA

PURPOSE: Prader-Willi syndrome (PWS) is a well-known genetic disorder, and microdeletion on chromosome 15 is the most common causal mechanism. Several previous studies have suggested that various environmental factors might be related to the pathogenesis of microdeletion in PWS. In this study, we investigated birth seasonality in Korean PWS. METHODS: A total of 211 PWS patients born from 1980 to 2014 were diagnosed by methylation polymerase chain reaction at Samsung Medical Center. Of the 211 pa

GeneticsBiochemistry, Genetics and Molecular Biology
15
Article|2 citations·2024
Validity and Reliability of the Korean Versions of the Food Allergy Quality of Life Questionnaire-Child Form and Teenager Form
Minyoung Jung, Sukyung Kim, Hye Won Yoo, Hye‐Young Kim, Minji Kim, Ji Young Lee, Boram Park, Jiwon Kim, Kangmo Ahn, Yechan Kyung, Jihyun Kim
SJR Q1Allergy Asthma and Immunology ResearchOA

We aimed to assess the validity and reliability of the Korean versions of the Food Allergy Quality of Life Questionnaire-Child Form (K-FAQLQ-CF) and the Food Allergy Quality of Life Questionnaire-Teenager Form (K-FAQLQ-TF). Patients aged 8-17 years with food allergy (FA) were enrolled and completed the Korean versions of the questionnaires, including the K-FAQLQ-CF, the Food Allergy Independent Measure-Child Form (K-FAIM-CF), and the Pediatric Quality of Life Inventory™ (K-PedsQL™ 4.0) for child

Immunology and AllergyMedicine

Research Areas

DermatologyImmunology and AllergyHealth, Toxicology and MutagenesisEpidemiologyPhysiologyEmergency Medical Services

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