Yong Jeong
Korea Advanced Institute of Science and Technology · Engineering
About the Lab
Professor Yong Jeong's research lab specializes in neuroscience and cognitive disorders, with a primary focus on the neural mechanisms underlying memory formation and dysfunction in Alzheimer’s disease. The lab investigates the role of hippocampal-retrosplenial cortex interactions during slow-wave sleep, particularly the dynamics of sharp-wave ripples (SWRs), in mediating long-term memory consolidation. Using advanced neurophysiological techniques such as in vivo electrophysiology and optogenetics, the lab aims to uncover how disruptions in these oscillatory networks contribute to early memory deficits in neurodegenerative diseases. Their work bridges systems neuroscience with translational research to identify potential biomarkers and therapeutic targets for early intervention in dementia.
Research Overview
Research Output Trend
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Selected Papers
2Alzheimer’s disease (AD) is the most common cause of dementia, characterized by prominent episodic memory dysfunction. Recent studies have suggested that there is a sequential mechanism in the memory deficit, with long-term ones preceding short-term ones. However, there is lack of explanation for these symptoms. Interaction between the hippocampus and retrosplenial cortex (RSC) during slow-wave sleep (SWS) is a crucial step for successful long-term memory formation. In particular, sharp-wave rip
Research Areas
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