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Yonghwan Kim

Sungkyunkwan University · Medicine

About the Lab

Professor Yonghwan Kim's research lab specializes in critical care medicine and clinical toxicology, focusing on early prediction of patient outcomes in severe medical emergencies such as cardiac arrest, organophosphate poisoning, and paraquat or glyphosate surfactant intoxication. The lab employs clinical scoring systems (e.g., SOFA, APACHE II, SAPS II), biomarkers (e.g., neuron-specific enolase, lactate), and advanced imaging (e.g., optic nerve sheath diameter) to improve risk stratification and guide intensive care decisions. A key research direction involves integrating physiological parameters and laboratory markers with neurological prognostication tools to enhance outcomes in post-resuscitation and poisoned patients. The lab’s work bridges emergency medicine, critical care, and toxicology with a strong emphasis on evidence-based prediction models.

critical caretoxicologyneurological prognosisbiomarker predictionICU outcomes

Research Overview

Papers
160
Total Citations
1,120
Papers (5y)
35
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
35total
2021
2022
2023
2024
2025
Citations per year (5y)
211total
20212022202320242025

Selected Papers

15
1
Article|75 citations·2014
Feasibility of Optic Nerve Sheath Diameter Measured on Initial Brain Computed Tomography as an Early Neurologic Outcome Predictor After Cardiac Arrest
Yong Hwan Kim, Jun Ho Lee, Chong Kun Hong, Kwang Won Cho, Jung Hoon Yeo, Mun Ju Kang, Yang Weon Kim, Kyoung Yul Lee, Jin Joo Kim, Seong Youn Hwang
SJR Q1Academic Emergency MedicineOA

OBJECTIVES: Few parameters are available to predict neurologic outcome of post-cardiac arrest patients in the early stage of treatment. Optic nerve sheath diameter (ONSD) has been used to indirectly assess intracranial pressure. This study evaluated whether ONSD, an additional parameter in initial brain computed tomography (CT) scans, can be an early predictor of neurologic outcome in post-cardiac arrest patients. METHODS: A total of 112 cardiac arrest patients between November 2012 and October

Emergency MedicineMedicine
2
Article|67 citations·2013
Performance Assessment of the SOFA, APACHE II Scoring System, and SAPS II in Intensive Care Unit Organophosphate Poisoned Patients
Yong Hwan Kim, Jung Hoon Yeo, Mun Ju Kang, Jun Ho Lee, Kwang Won Cho, Seong Youn Hwang, Chong Kun Hong, Young Hwan Lee, Yang Weon Kim
SJR Q2Journal of Korean Medical ScienceOA

This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitted to the ICU from September 2006 to December 2012 were retrospectively examined. The SOFA, APACHE II,

Health, Toxicology and MutagenesisEnvironmental Science
3
Article|44 citations·2013
Heart rate–corrected QT interval predicts mortality in glyphosate-surfactant herbicide–poisoned patients
Yong Hwan Kim, Jun Ho Lee, Chong Kun Hong, Kwang Won Cho, Yong Hwan Park, Yang Weon Kim, Seong Youn Hwang
SJR Q1The American Journal of Emergency Medicine
PollutionEnvironmental Science
4
Article|32 citations·2016
Effectiveness of the sequential organ failure assessment, acute physiology and chronic health evaluation II, and simplified acute physiology score II prognostic scoring systems in paraquat-poisoned patients in the intensive care unit
Jun Ho Lee, Seong Youn Hwang, Hye-Ran Kim, Yang Won Kim, Yang Won Kim, Mun Ju Kang, Kwang Won Cho, Dong Woo Lee, Yong Hwan Kim, Yong Hwan Kim
SJR Q2Human & Experimental Toxicology

OBJECTIVE: This study was conducted to assess the ability of the sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II scoring systems, as well as the simplified acute physiology score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with paraquat. This will assist physicians with risk stratification. MATERIAL AND METHODS: The medical records of 244 paraquat-poisoned patients admitted to the IC

SurgeryMedicine
5
Article|24 citations·2013
Performance Assessment of the SOFA, APACHE II Scoring System, and SAPS II in Intensive Care Unit Organophosphate Poisoned Patients
김용환, 여정훈, 강문주, 이준호, 조광원, 황성연, Chong Kun Hong, 이영환, 김양원
Journal of Korean Medical Science

This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitted to the ICU from September 2006 to December 2012 were retrospectively examined. The SOFA, APACHE II,

6
Article|23 citations·2021
Combination of neuron-specific enolase measurement and initial neurological examination for the prediction of neurological outcomes after cardiac arrest
Jae Hoon Lee, Yong Hwan Kim, Jun Ho Lee, Dong Woo Lee, Seong Youn Hwang, Chun Song Youn, Jihoon Kim, Min Seob Sim, Kyung Woon Jeung
SJR Q1Scientific ReportsOA

This study aimed to investigate the efficacy of the combination of neuron-specific enolase (NSE) measurement and initial neurological examination in predicting the neurological outcomes of patients with cardiac arrest (CA) by retrospectively analyzing data from the Korean Hypothermia Network prospective registry. NSE levels were recorded at 48 and 72 h after CA. The initial Full Outline of UnResponsiveness (FOUR) and Glasgow Coma Scale (GCS) scores were recorded. These variables were categorized

Emergency MedicineMedicine
7
Article|20 citations·2016
Prognostic Factors in Emergency Department Patients with Glyphosate Surfactant Intoxication: Point‐of‐Care Lactate Testing
Yong Hwan Kim, Jun Ho Lee, Kwang Won Cho, Dong Woo Lee, Mun Ju Kang, Kyoung Yul Lee, Young Hwan Lee, Seong Youn Hwang, Na Kyoung Lee
SJR Q2Basic & Clinical Pharmacology & ToxicologyOA

An increasing number of suicide attempts involve the ingestion of glyphosate surfactant; hence, clinical toxicologists may encounter severe cases of glyphosate surfactant intoxication. In several other clinical conditions, serum lactate is used to predict outcome. We investigated the relationship between lactate levels and 30-day mortality from glyphosate surfactant poisoning. This retrospective analysis involved 232 patients who were admitted to the emergency department after acute glyphosate s

PollutionEnvironmental Science
8
Article|15 citations·2015
Optimized conversion of L-lysine to L-pipecolic acid using recombinant lysine cyclodeaminase from Streptomyces pristinaespiralis
Sung Min Byun, Seongwook Jeong, Dae Haeng Cho, Yong Hwan Kim
SJR Q2Biotechnology and Bioprocess Engineering
Radiology, Nuclear Medicine and ImagingMedicine
9
Article|13 citations·2023
Coagulation measures after cardiac arrest (CMACA)
Hyo Joon Kim, Michael Kurz, Jung Hee Wee, Joo Suk Oh, Won Young Kim, In Soo Cho, Mi Jin Lee, Dong Hun Lee, Yong Hwan Kim, Chun Song Youn
SJR Q1PLoS ONEOA

BACKGROUND: During cardiac arrest (CA) and after cardiopulmonary resuscitation, activation of blood coagulation and inadequate endogenous fibrinolysis occur. The aim of this study was to describe the time course of coagulation abnormalities after out-of-hospital CA (OHCA) and to examine the association with clinical outcomes in patients undergoing targeted temperature management (TTM) after OHCA. METHODS: This prospective, multicenter, observational cohort study was performed in eight emergency

Emergency MedicineMedicine
10
Article|12 citations·2018
Effects of socioeconomic status, health behavior, and physical activity on the prevalence of metabolic syndrome
Yong Hwan Kim, Hong‐Kyu Kim, Haemi Jee
SJR Q2Journal of Exercise RehabilitationOA

Routine medical checkups have been provided by both the government-led and private hospitals for the purposes of prevention and early detection of diseases. Various studies were conducted with clinical results obtained from both government and private hospital based results. However, results from two types of health checkups have not been conducted. The results should be compared for the prevalence of metabolic disease in the aspects of socioeconomic status and health care behaviors to observe t

Public Health, Environmental and Occupational HealthMedicine
11
Article|11 citations·2016
Relative lower body circumferences are associated with the prevalence of metabolic syndrome and arterial stiffness
Yong Hwan Kim, Wi-Young So
SJR Q3Technology and Health Care

Body circumference is a known health-related factor. This cross-sectional study aimed to investigate the associations of relative lower body circumferences with metabolic syndrome (MetS) and arterial stiffness (AS) in 684 men aged > 40 (mean, 54.6 ± 8.5) years. Participants were measured for waist , thigh, and calf circumferences; underwent blood tests and blood pressure measurements to detect MetS; and received brachial ankle pulse wave velocity measurements to measure AS. The waist-to-thigh, w

Endocrinology, Diabetes and MetabolismMedicine
12
Article|10 citations·2011
A Case of Liver Abscess Caused byFusobacterium nucleatumin a Patient with Recurrent Periodontal Diseases
Yong Hwan Kim, Hee Jung Yoon, Chan Woong Park, Jung Ho Kim, Min Kyung Lee, Ki Bang Kim, Dong Jib Na, Jimyung Kim
SJR Q3Korean Journal of GastroenterologyOA

Fusobacteria are anaerobic gram-negative, non-spore forming bacilli found in normal flora of the oral cavity, urogenital tract, and gastrointestinal tract. Fusobacterium nucleatum has been seldom reported as a cause of liver abscess, particularly in immunocompetent hosts. A 55-year-old man with frequent periodontal disease visited our hospital with intermittent fever and headache for 2 months. Abdominal CT scan revealed an 8.2 × 6 cm mass in the right hepatic lobe with central low density. Absce

Infectious DiseasesMedicine
13
Article|9 citations·2017
Verification of the Optimal Chest Compression Depth for Children in the 2015 American Heart Association Guidelines: Computed Tomography Study
Yong Hwan Kim, Jun Ho Lee, Kwang Won Cho, Dong Woo Lee, Mun Ju Kang, Kyoung Yul Lee, Joung Hun Byun, Young Hwan Lee, Seong Youn Hwang, Na Kyoung Lee
SJR Q1Pediatric Critical Care Medicine

OBJECTIVE: The 2015 American Heart Association guidelines recommended pediatric rescue chest compressions of at least one-third the anteroposterior diameter of the chest, which equates to approximately 5 cm. This study evaluated the appropriateness of these two types by comparing their safeties in chest compression depth simulated by CT. DESIGN: Retrospective study with data analysis conducted from January 2005 to June 2015 SETTING:: Regional emergency center in South Korea. PATIENTS: Three hund

Emergency MedicineMedicine
14
Article|9 citations·2023
Effect of adjuvant thiamine and ascorbic acid administration on the neurologic outcomes of out-of-hospital cardiac arrest patients: A before-and-after study
Youn‐Jung Kim, Youn-Jung Kim, You Jin Lee, Yong Hwan Kim, Yong Hwan Kim, Won Young Kim
SJR Q1Resuscitation
Nutrition and DieteticsNursing
15
Article|8 citations·2003
Intramyocardial Transplantation of Circulating CD34+ cells: Source of Stem Cells for Myocardial Regeneration
Yong Hwan Kim
SJR Q2Journal of Korean Medical ScienceOA

This study was designed to investigate the increase in the number of circulating CD34+ cells after acute myocardial infarction (MI) and the differentiation of these cells to cardiomyocytes after transplantation into infarcted myocardium. The study involved five donor groups: MI (n=27), sham (n=26), granulocyte-colony stimulating factor (GCSF) (n=26), MI+GCSF (n=25), and control (n=25). Acute MI was induced by ligating the left anterior descending coronary arteries (LAD) of donor rats, and LAD of

GeneticsMedicine

Research Areas

Emergency MedicineSurgeryCultural StudiesRadiology, Nuclear Medicine and ImagingPhysiologySociology and Political Science

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