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Yooju Nam

Yonsei University · Medicine

About the Lab

Professor Yooju Nam's research lab focuses on clinical and translational studies in nephrology and infectious diseases, with a strong emphasis on biomarker discovery and patient outcomes. The lab investigates non-invasive predictors for kidney graft survival, particularly proteinuria's role in long-term transplant outcomes, and explores immune responses in vaccinated individuals infected with SARS-CoV-2 variants. Additionally, the lab examines the impact of systemic health factors—such as dyslipidemia and hypertension—on chronic kidney disease progression and postoperative complications. Recent work also addresses healthcare system challenges, including the effects of medical workforce shortages on inpatient physician practice patterns.

kidney transplantationproteinuriaSARS-CoV-2biomarkerschronic kidney disease

Research Overview

Papers
16
Total Citations
49
Papers (5y)
16
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
16total
2019
2020
2022
2024
Citations per year (5y)
49total
2019202020222024

Selected Papers

15
1
Article|25 citations·2022
Antibody Level Predicts the Clinical Course of Breakthrough Infection of COVID-19 Caused by Delta and Omicron Variants: A Prospective Cross-Sectional Study
Min Hyung Kim, Yooju Nam, Nak‐Hoon Son, Namwoo Heo, Bongyoung Kim, Eawha Kang, A-Reum Shin, Andrew Yang, Yoon Soo Park, Heejung Kim, Taeyoung Kyong, Yong Chan Kim
SJR Q1Open Forum Infectious DiseasesOA

Abstract Background Omicron variant viruses spread rapidly, even in individuals with high vaccination rates. This study aimed to determine the utility of the antibody against spike protein level as a predictor of the disease course of coronavirus disease 2019 (COVID-19) in vaccinated patients. Methods Between December 11, 2021, and February 10, 2022, we performed a prospective observational cohort study in South Korea, which included patients infected with Delta and Omicron variants. A multivari

Infectious DiseasesMedicine
2
Article|13 citations·2022
Vaccine Effect on Household Transmission of Omicron and Delta SARS-CoV-2 Variants
Yong Chan Kim, Bongyoung Kim, Nak‐Hoon Son, Namwoo Heo, Yooju Nam, A-Reum Shin, Andrew Yang, Min Hyung Kim, Taeyoung Kyong, Eawha Kang, Yoon Soo Park, Heejung Kim
SJR Q2Journal of Korean Medical ScienceOA

Immunisation of household members may help to mitigate the current pandemic.

Infectious DiseasesMedicine
3
Article|5 citations·2019
Incidence of Acute Kidney Injury after Adrenalectomy in Patients with Primary Aldosteronism
Jee Young Lee, Hyoungnae Kim, Hyung Woo Kim, Geun Woo Ryu, Yooju Nam, Seon Yeong Lee, Young Su Joo, Sangmi Lee, Jung Tak Park, Seung Hyeok Han, Shin‐Wook Kang, Tae‐Hyun Yoo
SJR Q2Electrolytes & Blood PressureOA

Incidence and risk of postoperative AKI were significantly higher in PA patients after surgical treatment. High ACR on the tumor side and high LI were associated with higher risk of AKI in PA patients compared to pheochromocytoma patients.

Endocrinology, Diabetes and MetabolismMedicine
4
Article|3 citations·2024
의대 증원 사태 후 한국 입원전담전문의의 근무 패턴 변화 연구
정지수, 남유주, 오주연, 이종찬, 온정헌, 이정환, 대한내과학회 입원의학연구회 연구위원회
대한내과학회지

목적: 최근 정부 정책에 의해 촉발된 의과대학 증원 사태는입원전담전문의의 근무에 영향을 미치고 있다. 본 논문에서는2024년 2월 22일에 시작된 전공의들의 사직서 제출 이후 생긴의료 공백 상태에서 의과대학 증원 사태가 입원전담전문의의 근무 패턴에 어떠한 영향을 미쳤는지 조사하고자 한다. 방법: 2024년 4월 2일부터 4월 30일까지 대한내과학회 입원의학연구회 및 외과계 입원전담전문의연구회에 속한 입원전담전문의를 대상으로 한 설문조사 방법을 사용하였다. 설문조사는개인 식별 정보를 제외하고 이메일을 통해 진행되었으며 응답자의 특성, 근무 유형, 근무 시간, 환자 부담, 보조 인력의 가용성및 의과대학 증원 사태 후 직무 범위 변화 등이 분석되었다. 결과: 63명의 입원전담전문의가 응답하였으며 남녀 비율은 균등하였고 중간 연령은 39세였다. 의과대학 증원 사태 이후 전일근무 비율이 22.2%에서 39.7%로 증가하였고 주간 근무 비율은감소하였다. 근무 시간도 주당 중앙값 40시간에서 4

5
Article|1 citations·2020
PROTEINURIA AT 1 YEAR AFTER KIDNEY TRANSPLANTATION AND LONG-TERM GRAFT SURVIVAL
Hyung Woo Kim, Geun Woo Ryu, Sangmi Lee, Shinchan Kang, Yooju Nam, Seon Yeong Lee, Kyu Ha Huh, Myoung Soo Kim, Yu Seun Kim, Beom Seok Kim
SJR Q1Transplantation

Background: There is a need for developing non-invasive biomarkers that can predict long-term kidney graft survival. Proteinuria occurs commonly after kidney transplantation and is a well-known risk factor for graft loss after kidney transplantation. However, there is no specific guideline for proteinuria in kidney transplant. The objective of this study is to clarify the association between proteinuria and long-term graft outcome based on clinical data at 1 year after kidney transplantation. Me

Pulmonary and Respiratory MedicineMedicine
6
Article|1 citations·2019
SAT-199 ASSOCIATION BETWEEN SERUM LIPID PROFILES AND PROGRESSION OF CKD: KNOW-CKD STUDY
S.Y. Lee, Ki Heon Nam, G. Lee, Yooju Nam, J.Y. Lee, Y.S. Joo, Seung Hyeok Han
SJR Q1Kidney International ReportsOA

Dyslipidemia has been linked to an increased risk of cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD). However, the role of individual lipid parameter in the development of in the progression of CKD is not well established.

EpidemiologyMedicine
7
Article|1 citations·2020
P0930SERUM LEVELS OF OSTEOPROTEGERIN ARE ASSOCIATED WITH OBESITY IN CHRONIC KIDNEY DISEASE
Yooju Nam, Seon Yeong Lee, Hyung Woo Kim, Jae Hyun Chang, Tae‐Hyun Yoo
SJR Q1Nephrology Dialysis Transplantation

Abstract Background and Aims Osteoprotegerin (OPG), which is an osteoclastic inhibitory factor, is associated with type 2 diabetes mellitus, severity of vascular calcification, coronary artery disease, and chronic kidney disease. Obesity is a risk factor for diabetes, and cardiovascular disease, however there are few studies about the relationship between OPG and obesity, especially in patients with CKD. This study aimed to investigate association between OPG level and obesity in a large-scale p

Orthopedics and Sports MedicineMedicine
8
Article|0 citations·2020
P0850SERUM OSTEOPROTEGERIN LEVELS ARE ASSOCIATED WITH AN INCREASED RISK OF DEVELOPING ANEMIA IN PATIENTS WITH NON DIALYSIS CHRONIC KIDNEY DISEASE
Yooju Nam, Seon Yeong Lee, Hyung Woo Kim, Jae Hyun Chang, Tae‐Hyun Yoo
SJR Q1Nephrology Dialysis Transplantation

Abstract Background and Aims Osteoprotegerin (OPG), which is an osteoclastic inhibitory factor, have been shown associated with adverse renal outcomes and progression of vascular calcification in chronic kidney disease (CKD) patients. Anemia and CKD-bone mineral disorders (CKD-MBD) are also frequently observed in these patients. Since CKD-MBD and anemia might be closely linked, therefore, we further examined whether OPG level as a marker for bone turnover can predict the future development of an

OncologyMedicine
9
Article|0 citations·2020
P0881ANEMIA SIGNIFICANTLY INCREASES RISK OF OSTEOPOROSIS IN PATIENTS WITH NON-DIALYSIS CHRONIC KIDNEY DISEASE
Seon Yeong Lee, Yooju Nam, Hyung Woo Kim, Jae Hyun Chang, Tae‐Hyun Yoo
SJR Q1Nephrology Dialysis Transplantation

Abstract Background and Aims Anemia was frequently observed in chronic renal failure patients. The risk of osteoporosis is higher in patients with chronic anemia. Chronic anemia also showed a close relationship with bone mineral density. However, few studies have been done whether anemia affects bone mineral density with chronic kidney disease(CKD) patient. Therefore, the aim of our study is to evaluate the relationship between anemia and bone mineral density(BMD) in a large sample of non-dialys

HematologyMedicine
10
Preprint|0 citations·2022
Vaccine-induced antibody level predicts the clinical course of breakthrough infection of COVID-19 caused by delta and omicron variants: a prospective observational cohort study
Min Hyung Kim, Yooju Nam, Nak‐Hoon Son, Namwoo Heo, Bongyoung Kim, Eawha Kang, A-Reum Shin, Andrew Yang, Yoon Soo Park, Heejung Kim, Taeyoung Kyong, Yong Chan Kim
medRxivOA

Abstract Background Omicron variant viruses spread rapidly, even in individuals with high vaccination rates. This study aimed to determine the utility of the antibody against the spike protein level as a predictor of the disease course of COVID-19 in vaccinated patients. Methods Between 11 December 2021 and 10 February 2022, we performed a prospective observational cohort study in South Korea, which included patients infected with delta –and –omicron variants. Multivariable logistic regression a

Infectious DiseasesMedicine
11
Article|0 citations·2019
SUN-273 ASSOCIATION BETWEEN BLOOD PRESSURE AND THE PROGRESSION OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH GLOMERULAR DISEASES
Kyoungsoo Park, S. Lee, Yooju Nam, G. Lee, Seung Hyeok Han
SJR Q1Kidney International ReportsOA

The KDIGO guideline recommends target BP < 130/80 mmHg in proteinuric patients with CKD. The guideline is largely based on many clinical studies in diabetic and hypertensive patients. However, there is lack of evidence that this BP goal can also be applied to patients with glomerular diseases. Here, we studied the relationship between BP and CKD progression in patients with glomerular diseases.

NephrologyMedicine
12
Article|0 citations·2019
SAT-257 THE ROLE OF NON-TRADITIONAL RISK FACTORS AND BIOMARKERS IN PREDICTION OF CARDIOVASCULAR EVENTS AND MORTALITY IN PATIENTS WITH CHRONIC KIDNEY DISEASE: RESULTS FROM THE KNOW-CKD
G. Lee, S.H. Han, Y.S. Joo, Yooju Nam, Kyoungsoo Park
SJR Q1Kidney International ReportsOA

In patients with chronic kidney disease (CKD), many non-traditional risk factors are associated with cardiovascular events (CVEs) and death. In this study, we conducted comprehensive analysis on whether non-traditional risk factors can predict the future adverse outcomes beyond traditional risk factors. In addition, we compared the predictability of each factor and aimed to establish the most efficient predictive model

NephrologyMedicine
13
Article|0 citations·2019
MON-039 SMALL KIDNEY SIZE RELATIVE TO BODY MASS IS A RISK FACTOR FOR RENAL FUNCTION DETERIORATION IN IGA NEPHROPATHY PATIENTS
Yooju Nam, S.Y. Lee, S. Lee, Y.S. Joo, Ki Heon Nam, J.T. Park
SJR Q1Kidney International ReportsOA

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. However, identifying IgAN patients at higher risks for renal function decline is still a challenge. Recent investigations have proposed kidney size to be a risk factor for renal function decline in kidney transplantation recipients. Therefore, this study aimed to investigate whether kidney size has an effect on renal function deterioration rate in patients with IgAN.

NephrologyMedicine
14
Article|0 citations·2019
SUN-028 PROGNOSTIC VALUE OF MESANGIAL C3 AND C4d DEPOSITION IN IgA NEPHROPATHY
S.Y. Lee, Ki Heon Nam, Kyoungsoo Park, Jee Soo Ha, Yooju Nam, S. Lee, Seung Hyeok Han
SJR Q1Kidney International ReportsOA

Activation of complement system can play an important role in the pathogenesis of IgA nephropathy (IgAN). C3 and C4d can be representative markers of alternative and lectin pathway, respectively. We studied whether mesangial C3 or C4d deposits can predict adverse renal outcome better than conventional risk factors and determined relative contribution of each pathway to disease progression.

NephrologyMedicine
15
Article|0 citations·2020
Efficacy of Statin Use in Patients Undergoing Peritoneal Dialysis
Hyung Woo Kim, Geun Woo Ryu, Shinchan Kang, Yooju Nam, Beom Seok Kim
SJR Q1Journal of the American Society of Nephrology

Background: The efficacy of statin uses in patients with PD have not been proven in large studies. Because most of studies included only HD patients or a small number of PD patients, there is lack of evidence whether statin have positive effect on PD patients or not. The aim of this study was to reveal the efficacy of statin uses in PD patients. Methods: A total 612 incident PD patients between January 2006 and August 2019 were included in this study. The primary outcome was all-cause mortality

NephrologyMedicine

Research Areas

NephrologyInfectious DiseasesOrthopedics and Sports MedicineEndocrinology, Diabetes and MetabolismPulmonary and Respiratory MedicineEpidemiology

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