Skip to main content

Young-Je Son

Seoul National University · Medicine

About the Lab

Professor Young-Je Son's research lab specializes in cerebrovascular diseases, with a primary focus on moyamoya disease (MMD) in adults. The lab investigates the long-term clinical and hemodynamic outcomes of revascularization surgery, evaluates stroke prevention strategies, and explores prognostic factors for complications. Their work integrates clinical outcomes, angiographic assessments, and advanced imaging to improve surgical decision-making and patient management.

moyamoya diseasecerebrovascular surgeryrevascularizationstroke preventionhemodynamic monitoring

Research Overview

Papers
81
Total Citations
1,803
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2019
2022
2023
2024
2025
Citations per year (5y)
45total
20192022202320242025

Selected Papers

15
1
Article|191 citations·2014
Long-Term Outcomes After Combined Revascularization Surgery in Adult Moyamoya Disease
Won‐Sang Cho, Jeong Eun Kim, Chang Hyeun Kim, Seung Pil Ban, Hyun‐Seung Kang, Young‐Je Son, Jae Seung Bang, Chul‐Ho Sohn, Jin Chul Paeng, Chang Wan Oh
SJR Q1Stroke

BACKGROUND AND PURPOSE: The surgical outcomes of adult moyamoya disease are rarely reported. We aimed to evaluate the long-term outcomes of combined revascularization surgery in patients with adult moyamoya disease. METHODS: Combined revascularization surgery consisting of superficial temporal artery-middle cerebral artery anastomosis with encephalodurogaleosynangiosis was performed on 77 hemispheres in 60 patients. Clinical, angiographic, and hemodynamic states were evaluated retrospectively us

RheumatologyMedicine
2
Review|180 citations·2017
Meta-analysis of the surgical outcomes of symptomatic moyamoya disease in adults
Jin Pyeong Jeon, Jeong Eun Kim, Won‐Sang Cho, Jae Seung Bang, Young‐Je Son, Chang Wan Oh
SJR Q1Journal of neurosurgery

OBJECTIVE The purpose of this study was to evaluate treatment outcomes of future stroke prevention, perioperative complications, and angiographic revascularization in adults with symptomatic moyamoya disease (MMD) according to treatment modalities and surgical techniques. METHODS A systemic literature review was performed based on searches of the PubMed, Embase, and Cochrane Central databases. A fixed-effects model was used in cases of heterogeneity less than 50%. Publication bias was determined

RheumatologyMedicine
3
Article|117 citations·2010
Analysis of Complications Following Decompressive Craniectomy for Traumatic Brain Injury
Seung Pil Ban, Young‐Je Son, Hee‐Jin Yang, Yeong Seob Chung, Sang Hyung Lee, Dae Hee Han
SJR Q2Journal of Korean Neurosurgical SocietyOA

A poor GCS score (≤ 8) and an age of ≥ 65 were found to be related to the occurrence of one of the above-mentioned complications. These results should help neurosurgeons anticipate these complications, to adopt management strategies that reduce the risks of complications, and to improve clinical outcomes.

NeurologyMedicine
4
Article|103 citations·2012
Analysis of the factors influencing bone graft infection after cranioplasty
Chang-Hyun Lee, Young Sub Chung, Sang Hyung Lee, Hee‐Jin Yang, Young‐Je Son
SJR Q1The Journal of Trauma: Injury, Infection, and Critical Care

Prognostic/therapeutic study, level IV.

NeurologyMedicine
5
Article|94 citations·2006
Therapeutic strategy for large vestibular schwannomas
Chul‐Kee Park, Hee‐Won Jung, Jeong Eun Kim, Young‐Je Son, Sun Ha Paek, Dong Gyu Kim
SJR Q1Journal of Neuro-Oncology
EpidemiologyMedicine
6
Article|89 citations·2014
The natural clinical course of hemodynamically stable adult moyamoya disease
Won‐Sang Cho, Young Seob Chung, Jeong Eun Kim, Jin Pyeong Jeon, Young‐Je Son, Jae Seung Bang, Hyun‐Seung Kang, Chul‐Ho Sohn, Chang Wan Oh
SJR Q1Journal of neurosurgeryOA

OBJECT: Moyamoya disease (MMD) is a rare cerebrovascular disease and its natural history is still unclear. The authors aimed to investigate the natural course of hemodynamically stable cases of adult MMD, with the analysis of stroke risk factors. METHODS: Two hundred forty-one patients were included in this retrospective study. One hundred sixty-six (68.9%) were female, and mean age (± SD) at first visit was 41.3 ± 12.0 years (range 18-69 years). Unilateral involvement was identified in 33 patie

RheumatologyMedicine
7
Article|62 citations·2014
A risk factor analysis of prospective symptomatic haemorrhage in adult patients with cerebral cavernous malformation
Jin Sue Jeon, Jeong Eun Kim, Young Seob Chung, Sohee Oh, Jun Hyong Ahn, Won‐Sang Cho, Young‐Je Son, Jae Seung Bang, Hyun‐Seung Kang, Chul‐Ho Sohn, Chang Wan Oh
SJR Q1Journal of Neurology Neurosurgery & PsychiatryOA

Prior symptomatic haemorrhage and MR appearance could be related to prospective symptomatic CM haemorrhage in adults. A prospective multicentre observational study is necessary to confirm our results.

NeurologyMedicine
8
Article|55 citations·2013
A retrospective analysis on the natural history of incidental small paraclinoid unruptured aneurysm
Jin Seok Jeon, Jun Hyong Ahn, Wooseong Huh, Young‐Je Son, Jungsik Bang, H.-S. Kang, Chul‐Ho Sohn, Chang Wan Oh, O-Ki Kwon, Jin-Ah Kim
SJR Q1Journal of Neurology Neurosurgery & Psychiatry

Although incidental small paraclinoid UIAs have a relatively lower rupture and growth risk, patients with high-risk factors, including aneurysm ≥4 mm, HTN, arterial branch-related aneurysms, and multiple aneurysms must be monitored closely. The limitation of the retrospective nature of this study should be taken into consideration.

NeurologyMedicine
9
Article|54 citations·2016
Incidence and risk factors of intracranial aneurysm: A national cohort study in Korea
Tackeun Kim, Heeyoung Lee, Soyeon Ahn, O-Ki Kwon, Jae Seung Bang, Gyojun Hwang, Jeong Eun Kim, Hyun‐Seung Kang, Young‐Je Son, Won‐Sang Cho, Chang Wan Oh
SJR Q1International Journal of Stroke

Background Estimations of the intracranial aneurysm incidence require long-term follow-up of a relatively large at-risk population; as a result, the incidence remains largely unknown. Aims To investigate the national incidence of intracranial aneurysm in a Korean population. Methods After excluding 18,604 potential subjects with a previous history of stroke (I6x.x), 998,216 subjects were included in this observational cohort. The primary endpoint was the earliest date of diagnosis of either unru

NeurologyMedicine
10
Article|51 citations·2017
Natural History and Risk Factor of Recurrent Hemorrhage in Hemorrhagic Adult Moyamoya Disease
Kang Min Kim, Jeong Eun Kim, Won‐Sang Cho, Hyun‐Seung Kang, Young‐Je Son, Moon Hee Han, Chang Wan Oh
SJR Q1Neurosurgery

BACKGROUND: Recurrent hemorrhage is a serious neurosurgical problem in adult moyamoya disease (MMD) patients. OBJECTIVE: To find the natural history and risk factors of recurrent hemorrhage in cases of adult hemorrhagic MMD. METHODS: One hundred seventy-six adult MMD patients presenting with hemorrhage were enrolled. Patients' medical records and radiological images were retrospectively reviewed. Clinical and radiological features of recurrent hemorrhage, and related risk factors were analyzed.

RheumatologyMedicine
11
Article|51 citations·2012
Surgical Outcome of Percutaneous Endoscopic Interlaminar Lumbar Diskectomy for Recurrent Disk Herniation After Open Diskectomy
Chi Heon Kim, Chun Kee Chung, Tae-Ahn Jahng, Hee‐Jin Yang, Young‐Je Son
Journal of Spinal Disorders & Techniques

PEID with dissection of the scar tissue from the medial facet joint rather than from the neural tissue may be an effective alternative surgical method for recurrent disk herniation.

Pathology and Forensic MedicineMedicine
12
Article|43 citations·2010
The effect of brain atrophy on outcome after a large cerebral infarction
S. H. Lee, Chang Wan Oh, J. H. Han, Chae‐Yong Kim, O-Ki Kwon, Young‐Je Son, Hee‐Joon Bae, Moon‐Ku Han, Young Seob Chung
SJR Q1Journal of Neurology Neurosurgery & Psychiatry

Brain atrophy may have an association with clinical outcome after a large stroke by a trend of saving patients from an MCO but also by interfering with their functional recovery.

EpidemiologyMedicine
13
Article|20 citations·2007
IMAGE-GUIDED SURGERY FOR TREATMENT OF UNRUPTURED MIDDLE CEREBRAL ARTERY ANEURYSMS
Young‐Je Son, Dae Hee Han, Jeong Eun Kim
SJR Q2Operative Neurosurgery

With the aid of navigation, we were able to easily locate MCA aneurysms and perform minimally invasive surgeries such as mini-craniotomies, tailored sylvian dissections, and successful clippings of unruptured MCA aneurysms. In addition, we obtained satisfactory cosmetic results.

NeurologyMedicine
14
Article|19 citations·2015
Stability of Cerebral Aneurysms After Stent-Assisted Coil Embolization
Won‐Sang Cho, Hyun Sook Hong, Hyun‐Seung Kang, Jeong Eun Kim, Young Dae Cho, O-Ki Kwon, Jae Seung Bang, Gyojun Hwang, Young‐Je Son, Chang Wan Oh, Moon Hee Han
SJR Q1Neurosurgery

BACKGROUND: The availability of stents has widened the indications of endovascular intervention for cerebral aneurysms. OBJECTIVE: To elucidate the effect of stents on radiologic outcomes and to analyze the risk factors for aneurysmal recanalization via propensity score matching. METHODS: From the 735 aneurysms treated with coil embolization with stents (n = 187) and without stents (n = 548) between 2009 and 2011, 157 propensity score-matched case pairs were selected. The recanalization rates an

NeurologyMedicine
15
Article|17 citations·1999
Comparison of localizing values of various diagnostic tests in non-lesional medial temporal lobe epilepsy
Young‐Je Son, Chun Kee Chung, Sang-Kun Lee, Kee Hyun Chang, Dong Soo Lee, Yung Nahn Yi, Hyun Jib Kim
SJR Q2SeizureOA
Psychiatry and Mental healthMedicine

Research Areas

NeurologyRheumatologyPulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingEpidemiologyPathology and Forensic Medicine

Dive deeper into Young-Je Son's research on Nubint

Open this lab's papers in the app to read with AI, summarize, and cite in your writing.