Younghoon Kim

BACKGROUND: Many bacterial components in indoor dust can evoke inflammatory pulmonary diseases. Bacteria secrete nanometre-sized vesicles into the extracellular milieu, but it remains to be determined whether bacteria-derived extracellular vesicles in indoor dust are pathophysiologically related to inflammatory pulmonary diseases. OBJECTIVE: To evaluate whether extracellular vesicles (EV) in indoor air are related to the pathogenesis of pulmonary inflammation and/or asthma. METHODS: Indoor dust

We report a new approach to building hierarchical superstructures using a shape-persistent porous organic cage, which acts as a premade secondary building unit, and coordination chemistry. To illustrate the principle, a zinc-metalated porphyrin box (Zn-PB), a corner-truncated cubic porous cage, was connected by suitable dipyridyl terminated bridging ligands to construct PB-based hierarchical superstructures (PSSs). The PSSs were stabilized not only by the coordination bonds between Zn ions and b

BACKGROUND: Viral pathogen-associated molecular patterns, such as dsRNA, disrupt airway tolerance to inhaled allergens. Specifically, the Th2 and Th17 cell responses are induced by low-dose dsRNA and the Th1-dominant response by high-dose dsRNA. OBJECTIVE: In this model, we evaluate the role of TNF-α in the development of adaptive immune dysfunction to inhaled allergens induced by airway sensitization with dsRNA-containing allergens. METHODS: A virus-associated asthma mouse model was generated v

Salt effect on gelling properties of fish protein isolate (FPI) prepared by acid- and alkali-aided extraction was investigated. Acid- or alkali-extracted FPI formed significantly better gel texture with 0% NaCl than with 3% NaCl. Texture properties of acid- or alkali-extracted FPI decreased as NaCl content increased, especially at 2% to 3% salt. Contrarily, salt significantly promoted texture qualities of conventional surimi gels. The effect was highlighted when they were subjected to low temper

Zinc finger proteins (ZFPs) play a key role in transcriptional regulation and serve as invaluable tools for gene modification and genetic engineering. Development of efficient strategies for labeling metalloproteins such as ZFPs is essential for understanding and controlling biological processes. In this work, we engineered ZFPs containing cysteine-histidine (Cys2-His2) motifs by metabolic incorporation of the unnatural amino acid azidohomoalanine (AHA), followed by specific protein labeling via

We successfully control the Ir(ppy)₃ needle-like aggregates in small-molecule based emitting layers by solvent mixture for improving the properties of OLEDs.

Abstract The aerobic oxidation of 5‐hydroxymethylfurfural (HMF) into 2,5‐furandicarboxylic acid (FDCA), a bio‐based plastic monomer, is an important process for the valorization of biomass. Here, manganese oxides of various oxidation states with identical morphologies and similar surface areas were synthesized by introducing oxygen vacancy sites, and they were investigated as heterogeneous catalysts for HMF oxidation. Mn 2 O 3 exhibited a remarkable catalytic efficiency due to synergistic effect

이 연구는 특성화고등학교 학생의 스마트폰 중독을 예방하고 그들의 수업몰입을 높이기 위하여 수행되었다. 이 연구의 목적을 달성하기 위해 스마트폰 중독 측정 도구(15문항)와 수업 몰입 측정 도구(21문항)로 구성된 설문지를 통해 전국 5개 권역 13개교 특성화고등학교 학생 1,014명을 대상으로 설문 조사를 실시하였다. 연구의 결과는 다음과 같다. 첫째, 특성화고등학교 학생들의 스마트폰 중독위험군이 일반 고등학교 학생들의 스마트폰 중독위험군보다 낮은 것으로 나타났다. 성별에 따른 스마트폰 중독위험군은 여학생의 스마트폰 중독 비율이 남학생보다 높게 나타났다. 학년이 낮을수록 스마트폰 중독 1요인(일상생활장애)이 높은 것으로 나타났다. 전공에 따른 스마트폰 중독 수준은 건축·토목 전공 학생들이 가장 높게 나타났다. 둘째, 특성화고등학교 학생들의 수업 몰입은 보통 수준으로 나타났다. 행동몰입은 높은 수준이었으며 인지 몰입, 감정 몰입은 보통 수준이었다. 성별에 따라서는 수업 몰입은 차이가

Purpose: This study, by comprehensively the characteristics of new Hanok application techniques with the proposed site application technology in the course of the design changes that have been accumulated through Hanok technology development the second stage business, by analyzing the range of reflection, new Considering the direction reflects the efficiency of the new Hanok application techniques. Method: new Hanok application technology, it was been established through research and development

Purpose: The purpose of this study is to integrate and analyze the three construction sites of new Han-ok style public buildings that have already been completed, while minimizing overlap with the contents of the existing research papers. From the design stage of the three sites to the construction process, application of technology and process management, we analyze them comprehensively. Method: The analysis method of this study summarized the research process and concept of the public new Han-

Purpose: This study analyzed the application of Japanese traditional architecture and the elements of contemporary architecture through the material granulation by Kengo Kuma, a Japanese architect. This study would like to confirm the characteristics of the modern interpretation of traditional Japanese architectural elements through the case study. Method: In this study, the nine cases of Kengo Kuma’s works, which expressed Japanese tradition, using the various materials through the granulation

Purpose: In previous studies, the conceptual definition, interpretation, and periodic division of traditional architecture in Japanese architecture were mixed without being clear. This study aims to establish a paradigm related to the form factors of traditional Japanese architecture and use it as a basic study to study the modernization and modern application of the traditional elements discussed in the future. Method: This study focuses on researching the academic definition, types and charact