Skip to main content

Yunsik Lee

Ulsan National Institute of Science and Technology · Computer Science

About the Lab

Professor Yunsik Lee's research lab specializes in sustainable chemistry and catalytic materials, focusing on the conversion of biomass-derived platform chemicals into high-value fuels and chemicals. Key research directions include the hydrogenation of 5-hydroxymethylfurfural (HMF) to 2,5-bis(hydroxymethyl)furan (BHMF) and its further transformation into alkoxymethyl furan derivatives as potential biodiesel alternatives, using selective heterogeneous catalysts such as Ru(OH)ₓ/ZrO₂ and Amberlyst-15. The lab also explores bioactive peptide-conjugates of hydroxycinnamic acids for enhanced antioxidant properties, with applications in cosmetics and food preservation. Additionally, the lab contributes to computational electronics through the development of advanced logic simulation algorithms, such as the multi-delay parallel (MDP) technique, for high-performance circuit design and analysis.

biomass conversioncatalysisbiodieselantioxidant peptideslogic simulation

Research Overview

Papers
129
Total Citations
885
Papers (5y)
18
Primary Field
Computer Science

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
18total
2020
2021
2022
2024
2025
Citations per year (5y)
223total
20202021202220242025

Selected Papers

15
1
Article|127 citations·2014
Tyrosine-mediated two-dimensional peptide assembly and its role as a bio-inspired catalytic scaffold
Hyung-Seok Jang, Jung‐Ho Lee, Yong-Sun Park, Young‐O Kim, Jimin Park, Tae‐Youl Yang, Kyoungsuk Jin, Jaehun Lee, Sunghak Park, Jae Myoung You, Ki‐Woong Jeong, Areum Shin
SJR Q1Nature CommunicationsOA
BiomaterialsMaterials Science
2
Article|53 citations·2016
Heterogeneous zirconia-supported ruthenium catalyst for highly selective hydrogenation of 5-hydroxymethyl-2-furaldehyde to 2,5-bis(hydroxymethyl)furans in various n-alcohol solvents
Jusung Han, Yo-Han Kim, Hyungseok Jang, Sung Yeon Hwang, Jonggeon Jegal, Jung Won Kim, Yoon‐Sik Lee
SJR Q1RSC Advances

5-Hydroxymethyl-2-furaldehyde (HMF) was hydrogenated to 2,5-bis(hydroxymethyl)furan (BHMF) (&gt;99% yield) in various <italic>n</italic>-alcohol solvents using a Ru(OH)<sub>x</sub>/ZrO<sub>2</sub> catalyst.

Biomedical EngineeringEngineering
3
Article|25 citations·2009
Synergistic antioxidative activities of hydroxycinnamoyl‐peptides
Seon‐Yeong Kwak, Hyosuk Seo, Yoon‐Sik Lee
SJR Q3Journal of Peptide Science

Antioxidants have become an important subject of study as an active ingredient for cosmetics and preservatives for food. We synthesized antioxidative peptide conjugates of hydroxycinnamic acids (HCAs) such as ferulic acid (FA), caffeic acid (CA), and sinapic acid (SA) by SPPS method. We measured their potential antioxidant properties by 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging test and lipid autoxidation inhibition test. When the antioxidative peptides, such as glutathione analog

PhysiologyMedicine
4
Article|24 citations·2007
Macroporous polystyrene-supported IBX amide: the improved oxidative properties in various solvents
Hyung‐Seok Jang, Woo‐Jae Chung, Yoon‐Sik Lee
SJR Q3Tetrahedron Letters
Organic ChemistryChemistry
5
Article|22 citations·2017
Highly Selective Catalytic Hydrogenation and Etherification of 5-Hydroxymethyl-2-furaldehyde to 2,5-Bis(alkoxymethyl)furans for Potential Biodiesel Production
Jung Won Kim, Yoon‐Sik Lee, Jusung Han, Yo-Han Kim, Byeong Jung, Sung Yeon Hwang, Jonggon Jegal
SJR Q3Synlett

5-Hydroxymethyl-2-furaldehyde (HMF) was hydrogenated to 2,5-bis(hydroxymethyl)furan (BHMF) in various n-alcohol solvents with more than 99% yield using Ru(OH) x /ZrO2 catalyst. The BHMF in the same solvents was subsequently etherified to give 2,5-bis(alkoxymethyl)furans (BAMFs, four examples) as potential biodiesels with moderate to good yields using Amberlyst-15.

Biomedical EngineeringEngineering
6
Article|10 citations·2013
Polymer-supported IBX amide for mild and efficient oxidation reactions
Hyung‐Seok Jang, Yo‐Han Kim, Young‐O Kim, Sang-Myung Lee, Jung Won Kim, Woo‐Jae Chung, Yoon‐Sik Lee
SJR Q1Journal of Industrial and Engineering Chemistry
Organic ChemistryChemistry
7
Article|8 citations·1994
Molecular Cloning of a Gene,DHS1, Which Complements a Drug-hypersensitive Mutation of the YeastSaccharomyces cerevisiae
Yun Sik Lee, Jiro Shimizu, Koji Yoda, Makari Yamasaki
SJR Q3Bioscience Biotechnology and Biochemistry

We isolated a Saccharomyces cerevisiae mutant, CH108, which shows hypersensitivity to cycloheximide, bleomycin, actinomycin D, 5-fluorouracil, and several other antibiotics. The mutant cells showed irregular shapes with swelling and were also hypersensitive to Zymolyase digestion. The mutant cell wall was swelled and twice as thick as the wild type cell wall. These defects were completely reversed by introduction of a genomic clone on a single-copy vector. Restriction analysis and sequencing sho

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|6 citations·2009
Preparation of a core–shell type MBHA resin and its application for solid-phase peptide synthesis
Jeong‐Hyun Choi, Tae Kyung Lee, Jang‐Woong Byun, Yoon‐Sik Lee
SJR Q3Tetrahedron Letters
Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|5 citations·1996
Bit-parallel multidelay simulation
Yun Sik Lee, Peter M. Maurer
SJR Q1IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems

The multidelay parallel (MDP) technique is a multidelay logic simulation algorithm that uses no timing wheel, or any other event-sorting mechanism. Instead, wide bit-fields containing net-values for several different times are used to resolve out-of-order events. Bit-parallel operations are performed to simulate gates at the required times. The MDP technique was originally designed to be implemented in hardware, but the current software version of the algorithm has proven to be competitive with

Hardware and ArchitectureComputer Science
10
Article|3 citations·1993
Parallel multi-delay simulation
Yun Sik Lee, Peter M. Maurer
International Conference on Computer Aided Design

The multi-delay parallel (MDP) technique is a multi-delay logic simulation algorithm that uses no event-sorting mechanism. Wide bit-fields and bit-parallel operations are used to resolve out-of-order events. Although the MDP technique was designed to be implemented in hardware, the software version has proven to be competitive with ordinary multi-delay simulation. Two versions of the MDP technique are presented: fixed alignment and variable alignment. The fixed alignment algorithm uses bit-field

Hardware and ArchitectureComputer Science
11
Article|3 citations·2007
Soft shell resins for solid‐phase peptide synthesis
Tae Kyung Lee, Jeong‐Hyun Choi, Sun‐Jong Ryoo, Yoon‐Sik Lee
SJR Q3Journal of Peptide Science

Soft shell (SS) resins with a lightly or noncross-linked shell layer were prepared by reducing the amount of cross-linking agent, divinylbenzene (DVB), during seed suspension polymerization from polystyrene (PS) resin. These SS resins have a lower swelling volume than that produced by normal cross-linking. Despite its lower swelling, however, SS (10-00) resin, which consists of the 1% DVB-cross-linked core and the noncross-linked surface layer, showed higher efficiency in peptide synthesis compa

Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
Article|3 citations·2013
Nanoprobes: Near‐Infrared SERS Nanoprobes with Plasmonic Au/Ag Hollow‐Shell Assemblies for In Vivo Multiplex Detection (Adv. Funct. Mater. 30/2013)
Homan Kang, Sinyoung Jeong, Younggeun Park, Joon-Hyuk Yim, Bong‐Hyun Jun, San Kyeong, Jin‐Kyoung Yang, Gunsung Kim, SoonGweon Hong, Luke P. Lee, Jong‐Ho Kim, Ho‐Young Lee
SJR Q1Advanced Functional MaterialsOA

NIR-sensitive SERS nanoprobes are fabricated by J.-H. Kim, H.-Y. Lee, D. H. Jeong, Y.-S. Lee and co-workers, who form hollow plasmonic Au/Ag shells, assembled on the surface of a silica nanosphere. On page 3719, it is shown that the signals from these NIR SERS nanoprobes are detectable through deep tissues of up to 8 mm, and exhibit the capability for in vivo multiplex detection.

Electronic, Optical and Magnetic MaterialsMaterials Science
13
Article|2 citations·2012
The Relationship among School Organizational Health, Personal Teacher Efficacy, Collective Teacher Efficacy and Teaching Professionalism
Yun-Sik Lee, Hyoshin Lee
The Journal of Korean Teacher Education
Information SystemsComputer Science
14
Article|2 citations·2009
The Criteria of Teacher Evaluation Concerned with Teacher Development Stage
Yun-Sik Lee, 이두영
The Journal of Korean Teacher EducationOA
EducationSocial Sciences
15
Article|2 citations·2012
A Study on the Relationship among Teachers' Perceived Principal's Transformational Leadership, Teacher's Leadership, Teacher Efficacy and School Organizational Effectiveness
Yun Sik Lee, 최상균
SJR Q1Journal of Educational Administration
Information SystemsComputer Science

Research Areas

Electrical and Electronic EngineeringInformation SystemsOrganic ChemistryMolecular BiologyBiomedical EngineeringComputer Networks and Communications

Dive deeper into Yunsik Lee's research on Nubint

Open this lab's papers in the app to read with AI, summarize, and cite in your writing.