探索全球顶尖大学的研究室——研究领域与主要论文一览无余。
Professor Seo Tae Seok's research lab specializes in the development and application of advanced carbon-based nanomaterials, particularly graphene and its derivatives, for environmental remediation, biomedical sensing, and next-generation DNA sequencing technologies. The lab focuses on innovative fabrication methods such as centrifugal vacuum evaporation to create 3D graphene sponges and free-standing films with tunable structures and functionalities. A key research direction involves leveraging the unique optical and surface properties of graphene quantum dots and photocleavable fluorescent nucleotides for high-sensitivity biosensors and sequencing-by-synthesis platforms. The lab also pioneers integrated microfluidic devices for rapid, automated detection of foodborne pathogens, demonstrating strong interdisciplinary integration of materials science, nanotechnology, and bioengineering.
Professor Juhwan Oh's research lab focuses on population health, with a strong emphasis on social determinants of health across the lifespan. The lab investigates critical public health challenges such as pandemic response, adolescent mental health, and the long-term impacts of early-life socioeconomic deprivation on physical and psychological development. Research spans global health policy, behavioral health, and health disparities, often employing longitudinal and multilevel data from low-, middle-, and high-income countries. The lab is particularly interested in how structural factors—such as poverty, gender, and social support—interact to shape health outcomes.
Professor Jong Ju Jung's research lab specializes in thyroid cancer and endocrine surgery, with a strong focus on improving surgical outcomes and developing predictive tools for lymph node metastasis in papillary thyroid cancer. The lab investigates minimally invasive surgical techniques—such as endoscopic and gasless endoscopic thyroidectomy—comparing their efficacy and safety to conventional open surgery. A key research direction involves the development and validation of clinical scoring systems, like the Yonsei Estimated Value (YEV), to predict lateral neck node metastasis and guide preoperative decision-making. The lab also explores dynamic risk stratification models in medullary and non-medullary thyroid cancers to enhance personalized treatment strategies.
Professor Chang Ho Oh's research lab specializes in transition-metal-catalyzed organic synthesis, with a focus on developing novel and efficient methodologies for constructing complex molecular architectures. The lab explores innovative cyclization reactions, including [3+2] cycloadditions, [2+2] cycloadditions, and domino processes involving silver and palladium catalysis, to access polycyclic compounds and heterocycles with high regio- and stereoselectivity. Their work emphasizes atom-economical, mild, and eco-friendly transformations, often enabling the synthesis of natural product-like scaffolds that are otherwise difficult to access using conventional methods.
Professor Joo Sang Lee's research lab focuses on translational cancer genomics and systems biology, with a central emphasis on identifying and validating synthetic lethal interactions for targeted cancer therapy. The lab integrates multi-omics data, particularly from TCGA, to discover clinically relevant genetic vulnerabilities across diverse tumor types. A key direction involves developing data-driven frameworks—such as ISLE—to prioritize synthetic lethal interactions with high translational potential, bridging the gap between preclinical screening and clinical application. The lab also explores innovative diagnostic techniques, including modified cytological methods for intraoperative pathology, and investigates fundamental biological mechanisms, such as genome dynamics in gene regulation.
Professor Ki-Bok Min's research lab specializes in geomechanics, enhanced geothermal systems (EGS), and fractured rock mechanics, with a strong focus on hydraulic stimulation, microseismicity monitoring, and coupled hydro-mechanical modeling in deep crystalline rock formations. The lab investigates fracture propagation mechanisms, stress-dependent permeability, and fluid transport in engineered geothermal systems, using advanced numerical modeling and field data from the Pohang EGS site in Korea. Their work integrates experimental, observational, and computational approaches to improve the understanding of reservoir stimulation and long-term performance in low-permeability rock environments.
Professor Jun-Won Jeong's research lab specializes in epigenetic mechanisms underlying acute myeloid leukemia (AML), with a primary focus on understanding drug resistance in leukemia stem cells (LSCs). The lab investigates epigenetic regulators such as BET proteins, PTEN phosphorylation, and histone methyltransferase G9a to decipher their roles in AML pathogenesis and treatment response. Current research directions include the molecular mechanisms of resistance to epigenetic therapies like BET and HDAC inhibitors, as well as the impact of signaling pathways on LSC survival and apoptosis. The lab integrates molecular and cellular biology techniques with clinical patient samples to identify novel therapeutic targets for AML.
Professor Guk-Hyung Kim's research lab specializes in plant virology and fungal virology, with a focus on mycoviruses that influence fungal pathogenicity and host interactions. The lab investigates hypovirulence-associated double-stranded RNA viruses in filamentous fungi, particularly Fusarium species, exploring their potential as biological control agents to reduce reliance on chemical fungicides. Key research directions include viral transmission mechanisms, especially overcoming vegetative incompatibility barriers via protoplast fusion, and understanding molecular interactions between viruses and their fungal hosts. The lab also contributes to the virology of plant-infecting viruses, such as potato virus X and tomato spotted wilt virus, through genomic and functional analyses.
Professor Chang Woo Lee's research lab focuses on the molecular mechanisms underlying cancer progression, with a central emphasis on the interplay between DNA damage response (DDR), ubiquitin-mediated regulation, and cellular metabolism. The lab investigates how dysregulation of E3 ligases and post-translational modifications—particularly ubiquitination and deacetylation—affect key mitotic regulators like BubR1, Bub3, and Cdc20, contributing to chromosomal instability and tumorigenesis. Additionally, the lab explores the role of epigenetic and metabolic regulators, such as Ssu72 and BEX4, in liver polyploidization and oncogenic transformation, revealing novel connections between cell cycle control, cytoskeletal dynamics, and stress response pathways. The integration of cell biology, epigenetics, and systems-level analysis defines the lab’s interdisciplinary approach to understanding disease mechanisms at the molecular level.
Professor Sung-Won Jo's research lab focuses on molecular and translational mechanisms in developmental biology, cancer biology, and regenerative medicine. Key research directions include the genetic regulation of tooth development and patterning—particularly involving signaling pathways such as Sonic hedgehog (Shh), Wnt, and BMP—and the role of genes like Sostdc1 and SM22 in tumorigenesis and fibrosis. The lab also investigates therapeutic targets in chronic diseases, including TGF-β signaling in pancreatic fibrosis and HBV mutation dynamics during antiviral therapy. Additionally, the lab explores clinical outcomes in orthopedic surgery, such as graft selection in high tibial osteotomy, reflecting a translational approach to musculoskeletal health.
Professor Ha-Il Kim's research lab focuses on the molecular mechanisms underlying metabolic diseases, particularly type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). The lab investigates the role of serotonin signaling—both central and peripheral—in regulating glucose homeostasis, insulin sensitivity, and β-cell function. Key research directions include the regulation of β-cell mass and identity through serotonin synthesis and signaling pathways, as well as the identification of novel therapeutic targets such as PPAR-γ, HTR2A, and HTR2B receptors. The lab integrates preclinical models with human studies to translate findings into potential treatments for metabolic disorders.
Professor Yong Sang Lee's research lab specializes in thyroid cancer, with a primary focus on surgical outcomes, lymph node dissection strategies, and the clinicopathologic characteristics of papillary thyroid carcinoma. The lab investigates the impact of surgical extent on complications and recurrence, particularly in low-risk and microcarcinoma cases, while also exploring targeted therapies for aggressive variants like anaplastic thyroid cancer. Their work integrates clinical data with molecular mechanisms, including cancer stem cell resistance and drug response to tyrosine kinase inhibitors.
Professor Incheol Shin's research lab focuses on the molecular mechanisms underlying cancer progression, with a particular emphasis on signaling pathways involving transcription factors, glucose metabolism, and extracellular matrix proteins. The lab investigates key regulators such as Akt, Forkhead transcription factors, glucose transporters (e.g., Glut1), and matricellular proteins (e.g., CCN family, ECM1, galectin-1) in breast cancer and other malignancies. Their work spans from molecular cell biology to translational oncology, exploring how these molecules influence tumor cell proliferation, survival, migration, and drug resistance. The lab employs a range of techniques including RNA interference, viral transduction, and functional assays in both in vitro and in vivo models.
Professor Sungchul Park's research lab focuses on health services research, particularly examining health care utilization, quality of care, and health policy outcomes within the Medicare population. The lab investigates disparities in access to high-quality Medicare Advantage (MA) plans across racial and ethnic groups, the impact of health insurance literacy on plan choice, and the effects of health system changes—such as the COVID-19 pandemic—on care access and utilization. A key focus is on improving health equity and care efficiency, especially for vulnerable populations like those with Alzheimer’s disease and related dementias (ADRD).
Professor Jo Il-ju's research lab specializes in developing advanced implantable biomedical devices for neuroscience and brain-machine interface applications. The lab focuses on designing flexible, transparent, and multi-functional neural probes that integrate electrophysiological recording, chemical stimulation, and optogenetic compatibility to enable long-term, high-fidelity neural interfacing. Key research directions include microfabrication of neural implants using novel materials like PEDOT:PSS and silicon-based microsystems, as well as innovative actuation mechanisms for low-power MEMS switches and reduced tissue trauma during implantation. The lab emphasizes biocompatibility, signal stability, and multi-modal functionality to address chronic neural recording challenges.
Professor Yun Jung Lee's research lab specializes in the design and synthesis of advanced nanomaterials for next-generation energy storage systems, with a strong focus on lithium-ion and lithium-air batteries. The lab uniquely integrates bio-inspired approaches—leveraging genetically engineered viruses as templates and scaffolds—to create high-performance, nanostructured electrode materials with controlled morphology, composition, and catalytic functionality. Key research directions include the development of Co-free high-nickel layered oxides, virus-directed synthesis of noble metal nanowires, and bimetallic or hybrid catalysts (e.g., Ru-based, MOF-based) for efficient oxygen reduction and evolution reactions. The lab emphasizes sustainable, bottom-up fabrication methods to enhance energy density, rate capability, and cycle stability in battery systems.
Professor Young Sun Kang's research lab focuses on the pathophysiological mechanisms linking metabolic syndrome, obesity, and organ damage, particularly in the kidney and vasculature. The lab investigates the roles of key signaling pathways such as the renin-angiotensin-aldosterone system (RAAS), chemokine systems (e.g., CCL2/CCR2), and growth factors (e.g., VEGF) in mediating inflammation, fibrosis, and vascular dysfunction. A significant portion of the work also explores the use of paramagnetic ions, especially manganese, as contrast agents in proton NMR imaging, emphasizing their biodistribution, relaxivity, and potential for targeted molecular imaging. The lab integrates molecular biology, cell culture models, and in vivo imaging to uncover novel therapeutic targets for metabolic and cardiovascular diseases.
Professor Yoo-Soo Yang's research lab specializes in developing exosome-based nanoplatforms for targeted drug delivery, particularly in cancer therapy. The lab focuses on engineering exosomes to display functional membrane proteins and therapeutic cargoes, leveraging their natural biocompatibility, low immunogenicity, and intrinsic targeting abilities. Key research directions include membrane protein delivery via fusogenic exosomes, exosome-mediated tumor microenvironment modulation, and the use of enzymatically active exosomes for enhanced tumor penetration and immune activation.
Professor Lee Myeong Min's research lab focuses on the molecular mechanisms underlying cell fate determination and developmental patterning in plants, with a primary emphasis on the Arabidopsis root epidermis. The lab investigates transcriptional regulatory networks, particularly those involving bHLH and MYB transcription factors, to understand how positional cues and feedback loops establish distinct cell types. Key research directions include the functional diversification of gene duplicates, hormone signaling integration (especially gibberellins), and the systems-level analysis of gene expression during cell differentiation. The lab employs a combination of genetic, molecular, and genomics approaches to dissect regulatory networks at single-cell resolution.
Professor Jo Sung-won's research lab focuses on developmental biology, molecular genetics, and disease mechanisms, with a particular emphasis on signaling pathways such as Sonic hedgehog (Shh), TGF-beta, and Wnt/BMP in organ development and disease progression. The lab investigates the genetic and molecular regulation of tooth patterning, pancreatic fibrosis, and colorectal carcinogenesis, integrating molecular biology, animal models, and clinical studies. Key research directions include long-range gene regulation, tissue-specific signaling, and translational applications in chronic diseases and cancer.
