Skip to main content

Byung Ho Lee

Yonsei University · 医学

研究室紹介

Professor Byung Ho Lee's research lab focuses on spinal disorders, particularly lumbar spinal stenosis and idiopathic scoliosis, with an emphasis on surgical outcomes, epidemiology, and the biological mechanisms underlying spinal degeneration. The lab investigates the role of inflammatory cytokines in ligamentum flavum hypertrophy and ossification, as well as the impact of vitamin D status on surgical recovery. Additionally, the lab contributes to veterinary and agricultural health through studies on parasitic infections like Eimeria in poultry, highlighting translational research across human and animal health. The research integrates clinical outcomes, molecular mechanisms, and population-based epidemiology to improve patient management and preventive strategies.

spinal stenosisidiopathic scoliosisinflammatory cytokinesvitamin DEimeria

Research Overview

Papers
336
Total Citations
4,438
Papers (5y)
81
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
81total
2022
2023
2024
2025
2026
Citations per year (5y)
365total
20222023202420252026

Selected Papers

15
1
Review|128 citations·2020
Lumbar Spinal Stenosis: Pathophysiology and Treatment Principle: A Narrative Review
Byung Ho Lee, Seong-Hwan Moon, Kyung‐Soo Suk, Hak‐Sun Kim, Jae‐Ho Yang, Hwan‐Mo Lee
SJR Q1Asian Spine JournalOA

Patients with lumbar spinal stenosis may exhibit symptoms such as back pain, radiating pain, and neurogenic claudication. Although long-term outcome of treatments manifests similar results for both nonsurgical and surgical treatments, positive effects such as short-term improvement in symptoms and decreased fall risk may be expected with surgery. Surgical treatment is basically decompression, and a combination of treatments can be added depending on the degree of decompression and the accompanyi

Pathology and Forensic MedicineMedicine
2
Article|108 citations·2021
Incidence and Surgery Rate of Idiopathic Scoliosis: A Nationwide Database Study
Sahyun Sung, Hyun Wook Chae, Hye Sun Lee, Sinae Kim, Ji-Won Kwon, Soo‐Bin Lee, Seong-Hwan Moon, Hwan‐Mo Lee, Byung Ho Lee
SJR Q2International Journal of Environmental Research and Public HealthOA

Idiopathic scoliosis is the most common cause of three-dimensional deformities of the spine. Most of the previous studies have been cross-sectional studies to estimate the prevalence in the general population. An age-matched, population-based study is performed using nationwide databases between 2011 and 2015. The incidence rates of idiopathic scoliosis by age group, sex, and region are identified. We also investigate the pattern of medical institution use and the surgery rate of patients with i

SurgeryMedicine
3
Article|89 citations·2012
Inflammatory Cytokines Induce Fibrosis and Ossification of Human Ligamentum Flavum Cells
Jin‐Oh Park, Byung Ho Lee, Young Mi Kang, Tae-Hwan Kim, Ji Young Yoon, Hyang Kim, Un-Hye Kwon, Kwang Lee, Hwan‐Mo Lee, Seong-Hwan Moon
Journal of Spinal Disorders & TechniquesOA

Inflammatory cytokines (IL-6, TNF-α, PGE2, and NO) seem to play a crucial role in hypertrophy and ossification of LF. Degenerated, herniated intervertebral disks, and facet arthrosis may influence LF through inflammatory cytokines and cause hypertrophy and ossification of LF.

Pathology and Forensic MedicineMedicine
4
Article|80 citations·2010
Prevalence and Cross-Immunity of Eimeria Species on Korean Chicken Farms
Byung Ho Lee, Woo Hyun Kim, Jipseol Jeong, Jeongmi Yoo, Yong‐Kuk Kwon, Byeong Yeal Jung, Jun Kwon, Hyun S. Lillehoj, Wongi Min
SJR Q2Journal of Veterinary Medical ScienceOA

Epidemiology of Eimeria species in poultry flocks is important to increase the effectiveness of vaccinations and prophylactic strategies on chicken farms. In this study, fecal samples from 356 chicken farms were collected randomly and examined for the prevalence of Eimeria species. Through microscopic examination, it was determined that 78.7% of the tested farms were positive in Eimeria-infection. Seven Eimeria species were detected in all the positive farms by PCR amplification of the internal

Animal Science and ZoologyAgricultural and Biological Sciences
5
Article|69 citations·2014
Perioperative complication and surgical outcome in patients with spine metastases: Retrospective 200-case series in a single institute
Byung Ho Lee, Jin‐Oh Park, Hak‐Sun Kim, Young-Chang Park, Hwan‐Mo Lee, Seong-Hwan Moon
SJR Q2Clinical Neurology and NeurosurgeryOA
SurgeryMedicine
6
Article|68 citations·1998
Anthelmintic β-hydroxyketoamides (BKAs)
Byung Ho Lee, Michael F. Clothier, Fred E. Dutton, George A. Conder, Sandra S. Johnson
SJR Q2Bioorganic & Medicinal Chemistry Letters
Plant ScienceAgricultural and Biological Sciences
7
Article|59 citations·2012
Prognostic Factor Analysis in Patients with Metastatic Spine Disease Depending on Surgery and Conservative Treatment: Review of 577 Cases
Byung Ho Lee, Tae-Hwan Kim, Hyun-Soo Chong, Eunsoo Moon, Jin‐Oh Park, Hak‐Sun Kim, Seung Hyun Kim, Hwan‐Mo Lee, Yong‐Jin Cho, Keung Nyun Kim, Seong-Hwan Moon
SJR Q1Annals of Surgical OncologyOA
SurgeryMedicine
8
Article|48 citations·2012
Changes in Vitamin D Status After Surgery in Female Patients With Lumbar Spinal Stenosis and Its Clinical Significance
Tae-Hwan Kim, Ji Young Yoon, Byung Ho Lee, H.-D. Jung, Moon Soo Park, Jin‐Oh Park, Eun-Su Moon, Hak‐Sun Kim, Hwan‐Mo Lee, Seong-Hwan Moon
SJR Q1Spine

Vitamin D deficiency was common in patients with LSS. However, vitamin D status was improved after decompressive surgery, and postoperative 25-OHD level was significantly correlated with surgical outcomes.

Pathology and Forensic MedicineMedicine
9
Article|46 citations·2009
The Effect and Safety of the Antithrombotic Therapies in Patients with Atrial Fibrillation and CHADS2 Score 1
Byung Ho Lee, Jae-Seok Park, Jae Hyung Park, Jong Seung Park, Jae Jin Kwak, Eui-Seock Hwang, Sook Kyoung Kim, Donghoon Choi, Young‐Hoon Kim, Hui‐Nam Pak
SJR Q1Journal of Cardiovascular ElectrophysiologyOA

BACKGROUND: The revised ACC/AHA/ESC 2006 guideline recommends either aspirin or warfarin for the prevention of ischemic stroke in patients with atrial fibrillation (AF) in CHADS(2) score 1. We hypothesized that warfarin is superior to aspirin therapy for the prevention of stroke without increasing bleeding complication in AF patients with CHADS(2) score 1. METHODS AND RESULTS: Among 1,502 patients (mean 62.4 +/- 13.8 years old, male 65.4%) who were treated for nonvalvular AF without previous str

Cardiology and Cardiovascular MedicineMedicine
10
Article|39 citations·2003
Restricted Conformation Analogues of an Anthelmintic Cyclodepsipeptide
Fred E. Dutton, Byung Ho Lee, Sandra S. Johnson, Eileen M. Coscarelli, Pil H. Lee
SJR Q1Journal of Medicinal Chemistry

Six analogues of the anthelmintic cyclodepsipeptide PF1022A were prepared, each containing a small ring fused to the macrocycle to restrict the number of conformations the larger ring can adopt. It was anticipated that such conformational changes could lead to enhanced biological activity and selectivity. The analogues form two series of three members each. In one series, a carbon-based molecular bridge joins the methyl of a leucine residue with the methyl of its closest lactic acid residue to f

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
Review|38 citations·2023
The Clinical Use of Osteobiologic and Metallic Biomaterials in Orthopedic Surgery: The Present and the Future
Sung-Ryul Choi, Ji-Won Kwon, Kyung‐Soo Suk, Hak‐Sun Kim, Seong-Hwan Moon, Si-Young Park, Byung Ho Lee
SJR Q2MaterialsOA

As the area and range of surgical treatments in the orthopedic field have expanded, the development of biomaterials used for these treatments has also advanced. Biomaterials have osteobiologic properties, including osteogenicity, osteoconduction, and osteoinduction. Natural polymers, synthetic polymers, ceramics, and allograft-based substitutes can all be classified as biomaterials. Metallic implants are first-generation biomaterials that continue to be used and are constantly evolving. Metallic

Biomedical EngineeringEngineering
12
Article|34 citations·2014
Postoperative quality of life in patients with progressive neuromuscular scoliosis and their parents
Kyung‐Soo Suk, Jin Hee Baek, Jin‐Oh Park, Hak‐Sun Kim, Hwan‐Mo Lee, Ji-Won Kwon, Seong-Hwan Moon, Byung Ho Lee
SJR Q1The Spine JournalOA
SurgeryMedicine
13
Article|33 citations·2014
Comparison of Effects of Nonoperative Treatment and Decompression Surgery on Risk of Patients with Lumbar Spinal Stenosis Falling
Byung Ho Lee, Tae-Hwan Kim, Moon Soo Park, Suhan Lim, Jin‐Oh Park, Hak‐Sun Kim, Ho‐Joong Kim, Hwan‐Mo Lee, Seong-Hwan Moon
SJR Q1Journal of Bone and Joint SurgeryOA

Therapeutic Level II. Retrospective analysis of prospectively collected data. See Instructions for Authors for a complete description of levels of evidence.

Pathology and Forensic MedicineMedicine
14
Article|33 citations·2009
Incremental predictive value of pre-procedural N-terminal pro-B-type natriuretic peptide for short-term recurrence in atrial fibrillation ablation
Hye Jin Hwang, Jung‐Woo Son, Byung Ho Nam, Boyoung Joung, Byung Ho Lee, Jin‐Bae Kim, Moon‐Hyoung Lee, Yangsoo Jang, Namsik Chung, Won Heum Shim, Seung-Yun Cho, Sung Soon Kim
SJR Q1Clinical Research in CardiologyOA
Cardiology and Cardiovascular MedicineMedicine
15
Article|32 citations·2012
Osteoporotic profiles in elderly patients with symptomatic lumbar spinal canal stenosis
Byung Ho Lee, Seong Hwan Moon, Ho‐Joong Kim, Hwan‐Mo Lee, Tae-Hwan Kim
SJR Q3Indian Journal of OrthopaedicsOA
Orthopedics and Sports MedicineMedicine

Research Areas

SurgeryPathology and Forensic MedicineOrganic ChemistryCardiology and Cardiovascular MedicinePolymers and PlasticsMolecular Biology

Byung Ho Leeの研究をNubintでさらに深く

この研究室の論文をアプリで開き、AIと共に読み、要約し、引用しましょう。