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Dong-Young Kim

Seoul National University · 医学

研究室紹介

Professor Dong-Young Kim's research lab specializes in structural biology and bioinformatics, with a focus on understanding the molecular mechanisms of heat-shock proteins, particularly HtrA family proteases and ClpX chaperones. The lab investigates the structural and functional dynamics of ATP-independent and ATP-dependent protease-chaperone systems, emphasizing their roles in protein quality control and cellular homeostasis. In parallel, the lab explores hardware-efficient deep learning accelerators by leveraging inherent sparsity in convolutional neural networks, aiming to optimize performance and energy efficiency in AI workloads across diverse computing platforms.

HtrA proteasesClpX chaperonessparsity-aware hardwareCNN acceleratorsprotein quality control

Research Overview

Papers
300
Total Citations
4,627
Papers (5y)
59
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
59total
2022
2023
2024
2025
2026
Citations per year (5y)
208total
20222023202420252026

Selected Papers

15
1
Article|119 citations·2011
Inverted papilloma of the nasal cavity and paranasal sinuses: A Korean multicenter study
Dong‐Young Kim, Sung‐Lyong Hong, Chul Hee Lee, Hong‐Ryul Jin, Jun Myung Kang, Bong‐Jae Lee, Il Joon Moon, Seung‐Kyu Chung, Ki‐Sang Rha, Seok Hyun Cho, Kyong Rae Kim, Sung Wan Kim
SJR Q1The Laryngoscope

OBJECTIVES/HYPOTHESIS: The study group for sinonasal tumors at the Korean Rhinologic Society analyzed the results of the Korean multicenter experience for sinonasal inverted papilloma (IP) surgeries. STUDY DESIGN: Multicenter cohort study and retrospective analysis. METHODS: In total, 939 patients diagnosed with sinonasal IP treated between 1998 and 2007 at 17 university hospitals were enrolled. Demographic data and information about previous surgeries, the origin and involved site of the tumor,

SurgeryMedicine
2
Article|110 citations·2017
ZeNA: Zero-Aware Neural Network Accelerator
Dongyoung Kim, Junwhan Ahn, Sungjoo Yoo
SJR Q3IEEE Design and Test

It has been observed that the majority of the kernel weights and input activations in the state-of-the-art convolution neural networks (CNNs) have zero values. This article proposes a CNN hardware accelerator that exploits this property to achieve significant performance and energy improvements.

Computer Vision and Pattern RecognitionComputer Science
3
Article|63 citations·2017
A novel zero weight/activation-aware hardware architecture of convolutional neural network
Dongyoung Kim, Junwhan Ahn, Sungjoo Yoo

It is imperative to accelerate convolutional neural networks (CNNs) due to their ever-widening application areas from server, mobile to IoT devices. Based on the fact that CNNs can be characterized by a significant amount of zero values in both kernel weights and activations, we propose a novel hardware accelerator for CNNs exploiting zero weights and activations. We also report a zero-induced load imbalance problem, which exists in zero-aware parallel CNN hardware architectures, and present a z

Computer Vision and Pattern RecognitionComputer Science
4
Article|52 citations·2017
Influencing factors on CPAP adherence and anatomic characteristics of upper airway in OSA subjects
Pona Park, Jin-Il Kim, Yoon Jae Song, Jae Hyun Lim, Sung Woo Cho, Tae‐Bin Won, Doo Hee Han, Dong‐Young Kim, Chae Seo Rhee, Hyun Jik Kim
SJR Q3MedicineOA

Although continuous positive airway pressure (CPAP) is the most effective treatment modality, poor adherence still remains a problem for obstructive sleep apnea (OSA) treatment and there is little evidence regarding how this might be improved. This study aims to analyze the anatomic and clinical factors of OSA subjects who failed to comply with CPAP therapy.The medical records of 47 OSA subjects who received CPAP therapy as a first-line treatment modality were retrospectively reviewed. The medic

PhysiologyMedicine
5
Review|48 citations·2015
Chronic Rhinosinusitis and the Coagulation System
Dong‐Young Kim, Seong Cho, Tetsuji Takabayashi, Robert P. Schleimer
SJR Q1Allergy Asthma and Immunology ResearchOA

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and severely affects quality of life in patients. Although various etiologic and pathogenic mechanisms of CRS have been proposed, the causes of CRS remain uncertain. Abnormalities in the coagulation cascade may play an etiologic role in many diseases, such as asthma and other inflammatory conditions. While studies on the relationship between asthma and dysregulated coagulation have been reported, the role of the co

OtorhinolaryngologyMedicine
6
Article|44 citations·2022
Deep Learning Application to Clinical Decision Support System in Sleep Stage Classification
Dong‐Young Kim, Dong‐Young Kim, Jeong‐Gun Lee, Yunhee Woo, Jaemin Jeong, Chulho Kim, Dong‐Kyu Kim, Dong‐Kyu Kim
SJR Q2Journal of Personalized MedicineOA

Recently, deep learning for automated sleep stage classification has been introduced with promising results. However, as many challenges impede their routine application, automatic sleep scoring algorithms are not widely used. Typically, polysomnography (PSG) uses multiple channels for higher accuracy; however, the disadvantages include a requirement for a patient to stay one or more nights in the lab wearing uncomfortable sensors and wires. To avoid the inconvenience caused by the multiple chan

PhysiologyMedicine
7
Article|38 citations·2020
EV-Ident: Identifying Tumor-Specific Extracellular Vesicles by Size Fractionation and Single-Vesicle Analysis
Dongyoung Kim, Hyun‐Kyung Woo, Chaeeun Lee, Yoo Hong Min, Sumit Kumar, Vijaya Sunkara, Hwi-Gyeong Jo, Young Joo Lee, Jisun Kim, Hong Koo Ha, Yoon‐Kyoung Cho
SJR Q1Analytical Chemistry

Tumor-derived extracellular vesicles (EVs) have emerged as a promising source of circulating biomarkers for liquid biopsies. However, understanding the heterogeneous physical and biochemical properties of EVs originating from multiple complex biogenesis pathways remains a major challenge. Here, we introduce EV-Ident for preparation of subpopulations of EVs in three different size fractions: large EVs (EV200 nm; 200–1 000 nm), medium EVs (EV100 nm; 100–200 nm), and small EVs (EV20 nm; 20–100 nm).

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|32 citations·2013
Effects of Surgical vs. Nonsurgical Therapy on Erectile Dysfunction and Quality of Life in Obstructive Sleep Apnea Syndrome: A Pilot Study
Hyun‐Woo Shin, Juhyun Park, Jong‐Wan Park, Chae‐Seo Rhee, Chul Hee Lee, Yang-Gi Min, Dong‐Young Kim
SJR Q1The Journal of Sexual Medicine

INTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is associated with erectile dysfunction (ED). The improvement of ED after medical therapy including continuous positive airway pressure (CPAP) or mandibular advancement devices (MADs) is still controversial. Furthermore, the efficacy of surgical treatment has been little investigated. AIM: The aim of this nonrandomized prospective study was to evaluate the effects of surgical (uvulopalatopharyngoplasty [UPPP]) and nonsurgical approaches (CPAP

PhysiologyMedicine
9
Article|30 citations·2019
AI-powered transmitted light microscopy for functional analysis of live cells
Dongyoung Kim, Yoo Hong Min, Jung Min Oh, Yoon‐Kyoung Cho
SJR Q1Scientific ReportsOA

Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of live cells. AIM provides accurate images of subcellular organelles; allows identification of cellular and functional characteristics (cell type, viability, and maturation stage); and facilitates live cell tracking and multimodality analysis of immun

BiophysicsBiochemistry, Genetics and Molecular Biology
10
Article|29 citations·2014
Treatment of Allergic Rhinitis Is Associated with Improved Attention Performance in Children: The Allergic Rhinitis Cohort Study for Kids (ARCO-Kids)
Dong‐Kyu Kim, Dong-Kyu Kim, Chae Seo Rhee, Doo Hee Han, Tae‐Bin Won, Dong‐Young Kim, Dong‐Young Kim, Jeong‐Whun Kim
SJR Q1PLoS ONEOA

BACKGROUND: It has been well known that pediatric allergic rhinitis was associated with poor performance at school due to attention deficit. However, there were no cohort studies for the effect of treatment of allergic rhinitis on attention performance in pediatric population. Thus, the aim of this study was to investigate whether attention performance was improved after treatment in children with allergic rhinitis. METHODS: In this ARCO-Kids (Allergic Rhinitis Cohort Study for Kids), consecutiv

Immunology and AllergyMedicine
11
Article|29 citations·2009
Oral administration of Uncariae rhynchophylla inhibits the development of DNFB-induced atopic dermatitis-like skin lesions via IFN-γ down-regulation in NC/Nga mice
Dong‐Young Kim, Jung‐A Jung, Taeho Kim, Sang-Wan Seo, Sung‐Ki Jung, Cheung‐Seog Park
SJR Q1Journal of Ethnopharmacology
DermatologyMedicine
12
Article|27 citations·2003
Videostrobokymographic Analysis of Benign Vocal Fold Lesions
Dong‐Young Kim, Lee-Suk Kim, Kwang Hyun Kim, Myung‐Whun Sung, Myung‐Whun Sung, Jong-Lyel Roh, Tack‐Kyun Kwon, Sang Joon Lee, Seung‐Ho Choi, Soo-Geun Wang, Mee-Young Sung, Mee-Young Sung
SJR Q2Acta Oto-Laryngologica

OBJECTIVES: Videostrobokymography (VSK) has recently been introduced. The aim of this study was to analyze vibratory patterns and objective parameters in various benign vocal fold lesions using VSK and to examine the efficacy of VSK in clinical applications. MATERIAL AND METHODS: Using VSK, we analyzed the vibration patterns of normal vocal folds, various benign lesions such as nodules, polyps, cysts and Reinke's edema and cases of unilateral vocal fold paralysis. We also calculated the objectiv

PhysiologyMedicine
13
Article|24 citations·2007
Primary and secondary fungal infections of the paranasal sinuses: Clinical features and treatment outcomes
Doo Hee Han, Soo-Youn An, Si Whan Kim, Dong‐Young Kim, Chae‐Seo Rhee, Chul Hee Lee, Yang‐Gi Min
SJR Q2Acta Oto-Laryngologica

The symptoms of chronic rhinosinusitis such as nasal obstruction, purulent rhinorrhea, and postnasal drip were commonly present in both primary and secondary infections, and the sphenoid sinus was commonly involved in secondary infection. The radiological findings in fungal sinusitis included haziness, calcification, and bone destruction of the involved sinuses. CT scans in 80% of the primary and 69% of the secondary cases revealed calcific densities in a paranasal soft tissue mass. Twenty-eight

OtorhinolaryngologyMedicine
14
Article|19 citations·2016
Therapeutic outcomes of mandibular advancement devices as an initial treatment modality for obstructive sleep apnea
Pona Park, Hyoung Won Jeon, Doo Hee Han, Tae‐Bin Won, Dong‐Young Kim, Chae‐Seo Rhee, Hyun Jik Kim
SJR Q3MedicineOA

Although continuous positive airway pressure (CPAP) is a highly efficacious treatment for obstructive sleep apnea (OSA), there is a need for alternative treatment options, such as sleep surgeries and mandibular advancement devices (MADs), to overcome the limitations of CPAP.This study aimed to analyze the therapeutic outcomes of OSA subjects who were treated with a MAD, and to estimate the clinical impact of MAD as a first-line treatment for OSA.Forty-seven patients diagnosed with OSA received a

PhysiologyMedicine
15
Article|19 citations·1999
Tailoring of the preferred orientation and microstructure in the deposition of BaTiO3 thin films using pulsed laser deposition
Dongyoung Kim, Soon-Gul Lee, Yong Ki Park, Soon Ja Park
SJR Q2Materials Letters
Materials ChemistryMaterials Science

Research Areas

PhysiologySurgeryOtorhinolaryngologyImmunology and AllergyMolecular BiologyComputer Vision and Pattern Recognition

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