Jae Chul Pyun
Yonsei University · 医学
研究室紹介
Professor Jae Chul Pyun's research lab specializes in the development of advanced nanomaterials and hybrid nanostructures for biomedical diagnostics and environmental applications. The lab focuses on enhancing the sensitivity and efficiency of analytical techniques such as chemiluminescence immunoassays and laser desorption/ionization mass spectrometry (LDI-MS) through innovative nanomaterial design. Key research directions include the synthesis of perovskite quantum dots, plasmonic and semiconductor heterostructures, and pyrocatalytic nanocomposites for real-time pathogen detection and energy harvesting. The lab also explores functional materials for point-of-care diagnostics, particularly in sepsis and infectious disease monitoring.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Chemiluminescence immunoassays have been widely employed for diagnosing various diseases. However, because of the extremely low intensity chemiluminescence signals, highly sensitive transducers, such as photomultiplier tubes and image sensors with cooling devices, are required to overcome this drawback. In this study, a hypersensitive photosensor was developed based on cesium lead bromide (CsPbBr<sub>3</sub>) perovskite quantum dots (QDs) with sufficient high sensitivity for chemiluminescence im
In this work, the chronoamperometry-based redox cycling of 3,3',5,5'-tetramethylbenzidine (TMB) was performed by using interdigitated electrode (IDE). The signal was obtained from two sequential chronoamperometric profiles: (1) with the generator at the oxidative potential of TMB and the collector at the reductive potential of TMB, and (2) with the generator at the reductive potential of TMB and the collector at the oxidative potential of TMB. The chronoamperometry-based redox cycling (dual mode
A combination nanostructured matrix with metal Au nanoislands and semiconductor TiO 2 nanowires is presented to enhance both desorption and ionization efficiency in laser desorption/ionization (LDI) mass spectrometry. The heterostructure of Au nanoislands on TiO 2 nanowires was fabricated via (1) TiO 2 nanowire synthesis through a modified wet-corrosion method and (2) Au nanoisland formation through thermal annealing of a sputtered Au layer on the TiO 2 nanowires. Herein, the synergistic effect