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Jae-Jin Song

Seoul National University · 神経科学

研究室紹介

Professor Jae-Jin Song's research lab specializes in neuromodulation and neuroimaging, focusing on the neural mechanisms underlying tinnitus, Parkinson’s disease, neuropathic pain, and depression. The lab employs advanced neurophysiological techniques such as EEG, PET, and tDCS to investigate brain network dysregulation, particularly thalamocortical dysrhythmia and the role of the rostral anterior cingulate cortex in tinnitus perception. A key focus is translating neurophysiological findings into clinical applications through neuromodulatory interventions and personalized treatment strategies.

tinnitusneuromodulationthalamocortical dysrhythmiaEEGtranscranial direct current stimulation

Research Overview

Papers
216
Total Citations
4,627
Papers (5y)
54
Primary Field
神経科学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
54total
2022
2023
2024
2025
2026
Citations per year (5y)
476total
20222023202420252026

Selected Papers

15
1
Article|252 citations·2018
Thalamocortical dysrhythmia detected by machine learning
Sven Vanneste, Jae‐Jin Song, Dirk De Ridder
SJR Q1Nature CommunicationsOA

Thalamocortical dysrhythmia (TCD) is a model proposed to explain divergent neurological disorders. It is characterized by a common oscillatory pattern in which resting-state alpha activity is replaced by cross-frequency coupling of low- and high-frequency oscillations. We undertook a data-driven approach using support vector machine learning for analyzing resting-state electroencephalography oscillatory patterns in patients with Parkinson's disease, neuropathic pain, tinnitus, and depression. We

Cognitive NeuroscienceNeuroscience
2
Review|88 citations·2012
Mapping Tinnitus-Related Brain Activation: An Activation-Likelihood Estimation Metaanalysis of PET Studies
Jae‐Jin Song, Dirk De Ridder, Paul Van de Heyning, Sven Vanneste
SJR Q1Journal of Nuclear MedicineOA

This study proves that PET is a useful modality for tinnitus research and solidifies human tinnitus research itself by confirming previously described brain areas involved in the generation and maintenance of tinnitus.

Sensory SystemsNeuroscience
3
Review|88 citations·2012
Transcranial Direct Current Stimulation in Tinnitus Patients: A Systemic Review and Meta-Analysis
Jae‐Jin Song, Sven Vanneste, Paul Van de Heyning, Dirk De Ridder
SJR Q2The Scientific World JOURNALOA

Although transcranial direct current stimulation (tDCS) has already been used to manage tinnitus patients, paucity of reports and variations in protocols preclude a comprehensive understanding. Hence, we conducted a meta-analysis based on systemic review to assess effectiveness of tDCS in tinnitus management and to compare stimulation parameters. PubMed was searched for tDCS studies in tinnitus. For randomized controlled trials (RCTs), a meta-analysis was performed. A total of 17 studies were id

NeurologyNeuroscience
4
Article|76 citations·2015
Dysfunctional Noise Cancelling of the Rostral Anterior Cingulate Cortex in Tinnitus Patients
Jae‐Jin Song, Sven Vanneste, Dirk De Ridder
SJR Q1PLoS ONEOA

These results may designate the role of the rostral ACC as the core of the descending noise cancellation system, and thus dysfunction of the rostral ACC may result in perception of tinnitus. The present study also opens a possibility of tinnitus modulation by neuromodulatory approaches targeting the rostral ACC.

Sensory SystemsNeuroscience
5
Article|73 citations·2013
Neural substrates predicting improvement of tinnitus after cochlear implantation in patients with single-sided deafness
Jae‐Jin Song, Andrea Kleine Punte, Dirk De Ridder, Sven Vanneste, Paul Van de Heyning
SJR Q2Hearing Research
Cognitive NeuroscienceNeuroscience
6
Article|72 citations·2013
Hyperacusis-associated pathological resting-state brain oscillations in the tinnitus brain: a hyperresponsiveness network with paradoxically inactive auditory cortex
Jae‐Jin Song, Dirk De Ridder, Nathan Weisz, Winfried Schlee, Paul Van de Heyning, Sven Vanneste
SJR Q1Brain Structure and Function
Sensory SystemsNeuroscience
7
Article|69 citations·2009
Unilateral Sensorineural Hearing Loss in Children
Jae‐Jin Song, Hyo Geun Choi, Seung Ha Oh, Sun O Chang, Chong Sun Kim, Jun Ho Lee
SJR Q1Otology & Neurotology

Based on the results, we propose all children with USNHL should have a TBCT scan because management, including genetic counseling and prognostic predictions of these cases, may be significantly influenced by the CT outcome. Moreover, the non-negligible rate of progressive nature of ipsilateral and contralateral SNHL in normal-looking TBCT group and in groups with inner ear malformations mandates longitudinal audiologic assessments for both ears

Sensory SystemsNeuroscience
8
Article|67 citations·2013
Onset-related differences in neural substrates of tinnitus-related distress: the anterior cingulate cortex in late-onset tinnitus, and the frontal cortex in early-onset tinnitus
Jae‐Jin Song, Sven Vanneste, Winfried Schlee, Paul Van de Heyning, Dirk De Ridder
SJR Q1Brain Structure and Function
Sensory SystemsNeuroscience
9
Article|60 citations·2011
Anxiolytics reduce residual dizziness after successful canalith repositioning maneuvers in benign paroxysmal positional vertigo
Hahn Jin Jung, Ja‐Won Koo, Chong Sun Kim, Ji Soo Kim, Jae‐Jin Song
SJR Q2Acta Oto-Laryngologica

Both groups demonstrated a significant improvement in DHI scores. However, the medication group showed significantly greater decrease in the functional (p = 0.018) and emotional (p = 0.030) subscale scores, as well as in the total DHI (p = 0.038) score.

NeurologyNeuroscience
10
Article|56 citations·2017
No auditory experience, no tinnitus: Lessons from subjects with congenital- and acquired single-sided deafness
Sang‐Yeon Lee, Dong Woo Nam, Ja‐Won Koo, Dirk De Ridder, Sven Vanneste, Jae‐Jin Song
SJR Q2Hearing Research
Sensory SystemsNeuroscience
11
Article|52 citations·2013
“Distressed aging”: the differences in brain activity between early- and late-onset tinnitus
Jae‐Jin Song, Dirk De Ridder, Winfried Schlee, Paul Van de Heyning, Sven Vanneste
SJR Q1Neurobiology of Aging
Sensory SystemsNeuroscience
12
Article|50 citations·2015
Sinus Wall Resurfacing for Patients With Temporal Bone Venous Sinus Diverticulum and Ipsilateral Pulsatile Tinnitus
Jae‐Jin Song, Young Jin Kim, So Young Kim, Yun Suk An, Kanghyeon Kim, Sang‐Yeon Lee, Ja‐Won Koo
SJR Q1Neurosurgery

BACKGROUND: Pulsatile tinnitus (PT) caused by venous sinus diverticulum is a relatively common, potentially incapacitating condition. Although treatment via an external approach or endovascular coiling has been reported, much remains unknown about the possible pathophysiological mechanisms and appropriate management of PT. OBJECTIVE: To review our case series of PT resulting from either sigmoid sinus diverticulum (SSD) or middle cranial fossa venous sinus diverticulum (MFD-VS) and to discuss the

NeurologyMedicine
13
Article|49 citations·2016
Objectification and Differential Diagnosis of Vascular Pulsatile Tinnitus by Transcanal Sound Recording and Spectrotemporal Analysis
Jae‐Jin Song, Gwang Seok An, Inyong Choi, Dirk De Ridder, So Young Kim, Hyun Seok Choi, Joo Hyun Park, Byung Yoon Choi, Ja‐Won Koo, Kyogu Lee
SJR Q1Otology & Neurotology

The present diagnostic approach may provide additional information regarding the origins of VPT cases as well as an efficient and objective diagnostic method. Furthermore, this approach may aid in the determination of appropriate imaging modalities, treatment planning, and evaluation of treatment outcomes.

Sensory SystemsNeuroscience
14
Article|49 citations·2014
Effects of congruent and incongruent visual cues on speech perception and brain activity in cochlear implant users
Jae‐Jin Song, Hyo‐Jeong Lee, Hyejin Kang, Dong Soo Lee, Sun O Chang, Seung Ha Oh
SJR Q1Brain Structure and Function
Experimental and Cognitive PsychologyPsychology
15
Article|44 citations·2016
Neural substrates predicting short-term improvement of tinnitus loudness and distress after modified tinnitus retraining therapy
Shin Hye Kim, Ji Hye Jang, Sang‐Yeon Lee, Jae Joon Han, Ja‐Won Koo, Sven Vanneste, Dirk De Ridder, Jae‐Jin Song
SJR Q1Scientific ReportsOA

Although tinnitus retraining therapy (TRT) is efficacious in most patients, the exact mechanism is unclear and no predictor of improvement is available. We correlated the extent of improvement with pre-TRT quantitative electroencephalography (qEEG) findings to identify neural predictors of improvement after TRT. Thirty-two patients with debilitating tinnitus were prospectively enrolled, and qEEG data were recorded before their initial TRT sessions. Three months later, these qEEG findings were co

Sensory SystemsNeuroscience

Research Areas

NeurologySensory SystemsCognitive NeuroscienceOtorhinolaryngologyMolecular BiologyCellular and Molecular Neuroscience

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