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Jae‐Hoon Ko

Sungkyunkwan University · 医学

研究室紹介

Professor Jae-Hoon Ko's research lab focuses on viral immunology, particularly host immune responses to emerging infectious diseases such as SARS-CoV-2 and human adenovirus (HAdV). The lab investigates humoral and cellular immunity, including neutralizing antibody production and T cell responses against SARS-CoV-2 variants, with an emphasis on breakthrough infections and vaccine-induced immunity. Additionally, the lab explores clinical diagnostics and epidemiological surveillance of viral outbreaks, including rapid serological testing and pathogen strain monitoring in outbreak settings.

viral immunologySARS-CoV-2T cell responseserological diagnosticsoutbreak surveillance

Research Overview

Papers
191
Total Citations
3,595
Papers (5y)
83
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
83total
2022
2023
2024
2025
2026
Citations per year (5y)
645total
20222023202420252026

Selected Papers

15
1
Article|168 citations·2016
Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients
Jae‐Hoon Ko, Ga Eun Park, Ji Yeon Lee, Ji‐Yong Lee, Sun Young Cho, Young Eun Ha, Cheol‐In Kang, Ji‐Man Kang, Yae‐Jean Kim, Hee Jae Huh, Chang‐Seok Ki, Byeong‐Ho Jeong
SJR Q1Journal of InfectionOA
Infectious DiseasesMedicine
2
Article|133 citations·2020
Neutralizing Antibody Production in Asymptomatic and Mild COVID-19 Patients, in Comparison with Pneumonic COVID-19 Patients
Jae‐Hoon Ko, Eun‐Jeong Joo, Su‐Jin Park, Jin Yang Baek, Won Duk Kim, Jaehwan Jee, Chul‐Joong Kim, Chul Hoi Jeong, Yae-Jean Kim, Hye Jin Shon, Eun‐Suk Kang, Young Ki Choi
SJR Q1Journal of Clinical MedicineOA

Objectives: To investigate antibody production in asymptomatic and mild COVID-19 patients. Methods: Sera from asymptomatic to severe COVID-19 patients were collected. Microneutralization (MN), fluorescence immunoassay (FIA), and enzyme-linked immunosorbent assay (ELISA) were performed. Results: A total of 70 laboratory-confirmed COVID-19 patients were evaluated, including 15 asymptomatic/anosmia, 49 mild symptomatic, and 6 pneumonia patients. The production of the neutralizing antibody was obser

Infectious DiseasesMedicine
3
Review|109 citations·2018
Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment of Stenotrophomonas maltophilia infections: a systematic review and meta-analysis
Jae‐Hoon Ko, Cheol‐In Kang, Patricia Cornejo‐Juárez, Kuo‐Ming Yeh, C.-H. Wang, S.Y. Cho, Mustafa Gökhan Gözel, Seon‐Hee Kim, Po‐Ren Hsueh, Noritaka Sekiya, Yasufumi Matsumura, Dong‐Gun Lee
SJR Q1Clinical Microbiology and InfectionOA
EndocrinologyBiochemistry, Genetics and Molecular Biology
4
Article|106 citations·2014
Clinical Presentation and Risk Factors for Cytomegalovirus Colitis in Immunocompetent Adult Patients
Jae‐Hoon Ko, Kyong Ran Peck, Won Jin Lee, Ji‐Yong Lee, S. Y. Cho, Young Eun Ha, Cheol‐In Kang, Doo Ryeon Chung, Youngsun Kim, Nam Yong Lee, K.-M. Kim, Jae‐Hoon Song
SJR Q1Clinical Infectious DiseasesOA

Steroid use and RBC transfusion within 1 month of the diagnosis of colitis were independent risk factors for development of CMV colitis in immunocompetent hosts.

EpidemiologyMedicine
5
Article|80 citations·2017
Serologic responses of 42 MERS-coronavirus-infected patients according to the disease severity
Jae‐Hoon Ko, Marcel A. Müller, Hyeri Seok, Ga Eun Park, Ji Yeon Lee, Sun Young Cho, Young Eun Ha, Jin Yang Baek, Kim Ys, Ji‐Man Kang, Yae‐Jean Kim, Ik Joon Jo
SJR Q2Diagnostic Microbiology and Infectious DiseaseOA
Infectious DiseasesMedicine
6
Article|49 citations·2023
3D GAN Inversion with Pose Optimization
Jae‐Hoon Ko, Kyusun Cho, Daewon Choi, Kwangrok Ryoo, Seungryong Kim
2023 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV)

With the recent advances in NeRF-based 3D aware GANs quality, projecting an image into the latent space of these 3D-aware GANs has a natural advantage over 2D GAN inversion: not only does it allow multi-view consistent editing of the projected image, but it also enables 3D reconstruction and novel view synthesis when given only a single image. However, the explicit viewpoint control acts as a main hindrance in the 3D GAN inversion process, as both camera pose and latent code have to be optimized

Computer Vision and Pattern RecognitionComputer Science
7
Article|39 citations·2019
Poor prognosis of Candida tropicalis among non-albicans candidemia: a retrospective multicenter cohort study, Korea
Jae‐Hoon Ko, Dong Sik Jung, Ji Yeon Lee, Hyun Ah Kim, Seong Yeol Ryu, Sook‐In Jung, Eun‐Jeong Joo, Shinhye Cheon, Kim Ys, Shin‐Woo Kim, Sun Young Cho, Cheol‐In Kang
SJR Q2Diagnostic Microbiology and Infectious Disease
Infectious DiseasesMedicine
8
Article|36 citations·2015
Bacteremic meningitis caused by Parvimonas micra in an immunocompetent host
Jae‐Hoon Ko, Jin Yang Baek, Cheol‐In Kang, Woo Joo Lee, Ji‐Yong Lee, Sun Young Cho, Young Eun Ha, Kim Ys, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae‐Hoon Song
SJR Q2Anaerobe
MicrobiologyImmunology and Microbiology
9
Article|32 citations·2017
Appropriate non-carbapenems are not inferior to carbapenems as initial empirical therapy for bacteremia caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae: a propensity score weighted multicenter cohort study
Jae‐Hoon Ko, Nancy Lee, Eun‐Jeong Joo, Soo‐youn Moon, J.‐K. Choi, D. A. Park, Kyong Ran Peck
SJR Q1European Journal of Clinical Microbiology & Infectious Diseases
Molecular MedicineBiochemistry, Genetics and Molecular Biology
10
Article|29 citations·2019
Ongoing outbreak of human adenovirus-associated acute respiratory illness in the Republic of Korea military, 2013 to 2018
Jae‐Hoon Ko, Hyeongtaek Woo, Hong Sang Oh, Song Mi Moon, Joon Young Choi, Jeong Uk Lim, Dong‐Hoon Kim, Junsu Byun, Soon‐Hwan Kwon, Daeyoun Kang, Jung Yeon Heo, Kyong Ran Peck
SJR Q2The Korean Journal of Internal MedicineOA

A large HAdV outbreak is currently ongoing in the Korean military, with a trend away from seasonality, and HAdV-55 is likely the predominant strain. Persistent efforts to control the outbreak, HAdV type-specific surveillance, and vaccine development are required.

EpidemiologyMedicine
11
Article|29 citations·2018
Changing epidemiology of non-albicans candidemia in Korea
Jae‐Hoon Ko, Dong Sik Jung, Ji Yeon Lee, Hyun Ah Kim, Seong Yeol Ryu, Sook‐In Jung, Eun‐Jeong Joo, Shinhye Cheon, Kim Ys, Shin‐Woo Kim, Sun Young Cho, Cheol‐In Kang
SJR Q2Journal of Infection and Chemotherapy
Infectious DiseasesMedicine
12
Article|25 citations·2019
Early cidofovir administration might be associated with a lower probability of respiratory failure in treating human adenovirus pneumonia: a retrospective cohort study
Jae‐Hoon Ko, Jeong Uk Lim, Joon Young Choi, Hong Sang Oh, Hongseok Yoo, Byung Woo Jhun, Kyungmin Huh, Kyong Ran Peck
SJR Q1Clinical Microbiology and InfectionOA
GeneticsBiochemistry, Genetics and Molecular Biology
13
Article|25 citations·2017
Suggested new breakpoints of anti-MERS-CoV antibody ELISA titers: performance analysis of serologic tests
Jae‐Hoon Ko, Marcel A. Müller, Hyeri Seok, Geun‐Young Park, Ji‐Yong Lee, S. Y. Cho, Young Eun Ha, Jin Yang Baek, S.-H. Kim, Ji‐Man Kang, Y.-J. Kim, Ik Joon Jo
SJR Q1European Journal of Clinical Microbiology & Infectious DiseasesOA
Infectious DiseasesMedicine
14
Article|21 citations·2014
Risk factors for cytomegalovirus gastrointestinal diseases in adult patients with cancer
Jae‐Hoon Ko, Kyong Ran Peck, Won Jae Lee, Kyungmin Huh, Jeong Rae Yoo, Kihyun Kım, S. Y. Cho, Young Eun Ha, Cheol‐In Kang, Doo Ryeon Chung, Chul Won Jung, Youngsun Kim
SJR Q1European Journal of Clinical Microbiology & Infectious Diseases
EpidemiologyMedicine
15
Article|20 citations·2024
Omicron BA.2 breakthrough infection elicits CD8 + T cell responses recognizing the spike of later Omicron subvariants
Sang-Hoon Kim, Jihye Kim, Sungmin Jung, Ji Yun Noh, Jin Nam Kim, Heedo Park, Young Goo Song, Kyong Ran Peck, Su‐Hyung Park, Man‐Seong Park, Jae‐Hoon Ko, Joon Young Song
SJR Q1Science Immunology

Here, we examine peripheral blood memory T cell responses against the SARS-CoV-2 BA.4/BA.5 variant spike among vaccinated individuals with or without Omicron breakthrough infections. We provide evidence supporting a lack of original antigenic sin in CD8 + T cell responses targeting the spike. We show that BNT162b2-induced memory T cells respond to the BA.4/BA.5 spike. Among individuals with BA.1/BA.2 breakthrough infections, IFN-γ–producing CD8 + T cell responses against the BA.4/BA.5 spike incr

Infectious DiseasesMedicine

Research Areas

Infectious DiseasesEpidemiologyMolecular MedicineSurgeryComputer Networks and CommunicationsOncology

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