Jeong Eun Lee

Retinal microglia normally occupying uninjured tissue display a continuous, dynamic behavior that suggests functions of tissue surveillance and intercellular communication. Microglial behavior is highly regulated by, and immediately responsive to, focal tissue injury and may constitute a therapeutic cellular response to focal laser photocoagulation. Ex vivo live imaging in the retina is an experimental approach well suited to the study of dynamic aspects of microglial physiology.

본 연구는 청소년이 지각한 가족, 학교, 지역사회 요인들이 청소년의 학교적응의 연속선상에 있는 문제행동, 학교생활흥미, 학업성적에 각각 어떻게 영향을 미치는지, 성별에 따라 어떻게 다른지 분석하는 것을 목적으로 하였다. 이를 위해 한국청소년패널 3차년도 데이터를 이용하여 고등학교 1학년에 재학 중인 남녀 학생 3,085명을 대상으로 다중회귀분석을 실시하였다. 분석결과, 남녀 공통적으로 문제행동에는 가족분위기, 친구문제행동, 또래애착이, 학교생활흥미에는 친구문제행동, 또래애착, 교사애착이, 학업성적에는 부모애착, 부모의 진로관심, 교사애착이 영향을 미치는 요인으로 밝혀졌다. 또한 성별에 따라 이러한 영향에 다소 차이가 있었다. 이러한 결과를 종합할 때, 학생들의 학교생활부적응에 대한 문제해결방안 수립시 성별 및 학교생활부적응의 양상을 고려한 다양한 접근이 필요하다.

본 연구는 사회복지 종사자를 대상으로 그들이 경험하는 클라이언트 폭력과 이로 인한 개인 및 조직 차원의 결과들간의 구조적 관계를 분석하였다. 조사대상은 서울시 소재 종합사회복지관, 노인복지시설, 장애인복지시설, 아동복지시설 등의 종사자 432명이다. 분석결과, 클라이언트 폭력은 사회복지 종사자의 스트레스, 소진, 조직몰입, 이직의도에 직ㆍ간접적으로 영향을 미치는 것으로 나타났다. 즉, 사회복지 종사자가 경험한 클라이언트 폭력은 직접적으로 소진에 영향을 미치는 한편, 인지된 스트레스를 매개로 하여 소진과 조직몰입에 영향을 미치고, 다시 조직몰입을 통해 이직의도에 영향을 미치는 것으로 나타났다. 이러한 결과를 바탕으로 클라이언트 폭력 예방 및 사회복지시설 종사자의 대처능력 향상의 중요성 및 대안을 제시하였다.

OBJECTIVE: To explore the neuroanatomic basis of amnestic mild cognitive impairment (aMCI) in patients with Parkinson disease (PD; aMCI-PD(+)) and without PD (aMCI-PD(-)). METHODS: A total of 119 patients with aMCI (aMCI-PD(-), n = 78, and aMCI-PD(+), n = 41) underwent T1-weighted MRI, and the image data were analyzed using voxel-based morphometry. RESULTS: No significant differences in demographic characteristics or general cognition were found between patients with aMCI-PD(-) and aMCI-PD(+). C

The study of cancer in patients treated with dialysis in Korea has not been reported. The aim of this study was to investigate the incidence and mortality of cancer among patients on dialysis in Korea. The study subjects were 106 cancer patients (2.3%) out of 4,562 end-stage renal disease (ESRD) patients maintained on hemodialysis (HD) or peritoneal dialysis (PD) at Yonsei University Health System from 1996 to 2005. We excluded patients in whom the diagnosis of cancer preceded dialysis or those

We found that fluid overload and malnutrition status were more common in elderly HD patients compared with young HD patients. PhA was a significant independent factor in fluid overload status and malnutrition in these HD patients. Thus, our results indicated that PhA assessed by BIA might be a clinically useful method for assessing nutritional and hydration status in elderly HD patients.

본 연구에서는 잠재유형분석(LCA)을 통해 사회적 배제 집단의 유형을 분류하고, 성별과 학력에 따라 이들 유형의 분포가 어떻게 달라지는지 살펴보았다. 분석을 위해 한국복지패널 2차년도(2007년) 자료를 사용하였으며, 사회적 배제는 경제(소득, 소비), 근로, 주거, 건강의 4개 차원(5개 항목)으로 구분하였다. 분석결과, 사회적 배제의 잠재적 유형은 비배제집단(69.1%)과 3개의 배재집단(30.9%) - 근로빈곤집단(8.3%), 건강배제집단(15.6%), 중복배제집단(7.0%) - 등 4개로 분류되었다. 여성가구주 가구가 배제집단에 속할 확률이 남성가구주 가구에 비해 2배 이상 높았다. 또한 성별에 따른 배제집단의 유형별 분포는 여성가구주 가구의 경우 건강배제집단(25.0%)에 속할 확률이 근로배제집단(14.6%)과 중복배제집단(12.8%)에 비해 높았으며, 남성가구주 가구의 경우는 중복배제집단(4.9%)에 속할 확률이 근로배제집단(9.1%)과 건강배제집단(9.6%)에 비해 낮았

We demonstrated that the effect of circulating levels of FGF-23 on the risk of ESRD is accounted for by circulating levels of TNFR1. We confirmed that circulating levels of FGF-23 have an independent effect on all-cause mortality in T2D.

Significance Statement Steroid resistance, relapse, and side effects are common issues in use of high-dose steroids as first-line treatment for adult minimal change nephrotic syndrome. Tacrolimus is used as a steroid-sparing immunosuppressant to reduce adverse effects of long-term or repeated steroid treatment, but no large-scale randomized study has compared combined tacrolimus and low-dose steroid with high-dose steroid in treating minimal change nephrotic syndrome in adults. In this open-labe

The study of cancer in patients treated with dialysis in Korea has not been reported. The aim of this study was to investigate the incidence and mortality of cancer among patients on dialysis in Korea. The study subjects were 106 cancer patients (2.3%) out of 4,562 end-stage renal disease (ESRD) patients maintained on hemodialysis (HD) or peritoneal dialysis (PD) at Yonsei University Health System from 1996 to 2005. We excluded patients in whom the diagnosis of cancer preceded dialysis or those

BACKGROUND: Chronic kidney disease (CKD) has emerged as a mounting public health issue worldwide; therefore, prompt identification and prevention are imperative in mitigating CKD-associated complications and mortality rate. We aimed to compare the predictive powers of the homeostatic model assessment for insulin resistance (HOMA-IR) and the metabolic score for insulin resistance (METS-IR) for CKD incidence in middle-aged and older adults. METHODS: This study used longitudinal prospective cohort

BACKGROUND: Although frozen adipose tissue is frequently used for soft tissue augmentation, the viability of frozen fat remains a controversy. The cryopreservation of adipose tissue is important for the future use of adipose-derived stem cells (ASCs) and adipocytes. OBJECTIVE: To determine whether optimal cryopreservation techniques with regard to the addition of cryopreservative agents and preservation temperature is essential for the long-term storage of adipose tissue and whether ASCs from cr

BACKGROUND: Hemodialysis (HD) patients have multiple causes of immune dysfunction and poor immune response to influenza vaccination. We investigated the antibody response rate to a pandemic H1N1/2009 influenza vaccination and clinical parameters influencing the induction of antibody responses in HD patients. METHODS: A total of 114 HD patients were vaccinated with a monovalent adjuvanted H1N1 inactivated influenza vaccine. Titers of neutralizing antibodies were evaluated by hemagglutination inhi