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Jin Chul Paeng

Seoul National University · 医学

研究室紹介

Professor Jin Chul Paeng's research lab specializes in molecular imaging and nuclear medicine, focusing on the clinical application of PET and SPECT tracers for accurate diagnosis, treatment planning, and prognosis prediction in oncology and neurological disorders. The lab investigates tumor heterogeneity using radiomic features from FDG-PET/CT to predict treatment response in lung cancer, evaluates advanced internal radiation therapy dosimetry using ⁹⁰Y-microsphere PET/CT, and explores novel tracers like ¹¹C-methionine for improved epilepsy surgery evaluation. The lab also advances multimodal imaging techniques to enhance diagnostic accuracy in musculoskeletal and oncologic conditions.

molecular imagingPET/CTtumor heterogeneityradiation dosimetryoncology imaging

Research Overview

Papers
412
Total Citations
6,533
Papers (5y)
100
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
100total
2022
2023
2024
2025
2026
Citations per year (5y)
241total
20222023202420252026

Selected Papers

15
1
Article|163 citations·2009
Prediction of Tumor Recurrence by 18F-FDG PET in Liver Transplantation for Hepatocellular Carcinoma
Jeong Won Lee, Jin Chul Paeng, Keon Wook Kang, Hyun Woo Kwon, Kyung‐Suk Suh, June‐Key Chung, Myung Chul Lee, Dong Soo Lee
SJR Q1Journal of Nuclear MedicineOA

In this study, (18)F-FDG PET was an independent and significant predictor of tumor recurrence. In liver transplantation for HCC, (18)F-FDG PET can provide effective information on the prognosis for tumor recurrence and the selection of adequate candidates for liver transplantation.

HepatologyMedicine
2
Article|102 citations·2013
Total lesion glycolysis by 18F-FDG PET/CT is a reliable predictor of prognosis in soft-tissue sarcoma
Eun Seok Choi, Seung-Gyun Ha, Han‐Soo Kim, Jae Hong Ha, Jin Chul Paeng, Ilkyu Han
SJR Q1European Journal of Nuclear Medicine and Molecular Imaging
Pulmonary and Respiratory MedicineMedicine
3
Article|74 citations·2011
Imaging sensitivity of dedicated positron emission mammography in relation to tumor size
Jae Seon Eo, In Kook Chun, Jin Chul Paeng, Keon Wook Kang, Sang Mi Lee, Wonshik Han, Dong‐Young Noh, June-Key Chung, Dong Soo Lee
SJR Q1The BreastOA
Radiology, Nuclear Medicine and ImagingMedicine
4
Article|69 citations·2012
Metabolic and metastatic characteristics of ALK-rearranged lung adenocarcinoma on FDG PET/CT
Hongyoon Choi, Jin Chul Paeng, Dong‐Wan Kim, Jake June-Koo Lee, Chang Min Park, Keon Wook Kang, June‐Key Chung, Dong Soo Lee
SJR Q1Lung Cancer
Pulmonary and Respiratory MedicineMedicine
5
Article|64 citations·2015
PET/CT-Based Dosimetry in 90Y-Microsphere Selective Internal Radiation Therapy
Yoo Sung Song, Jin Chul Paeng, Hyo‐Cheol Kim, Jin Wook Chung, Gi Jeong Cheon, June-Key Chung, Dong Soo Lee, Keon Wook Kang
SJR Q3MedicineOA

⁹⁰Y PET/CT can be acquired after ⁹⁰Y-microsphere selective radiation internal therapy (SIRT) to describe radioactivity distribution. We performed dosimetry using ⁹⁰Y-microsphere PET/CT data to evaluate treatment efficacy and appropriateness of activity planning from (99m)Tc-MAA scan and SPECT/CT. Twenty-three patients with liver malignancy were included in the study. (99m)Tc-MAA was injected during planning angiography and whole body (99m)Tc-MAA scan and liver SPECT/CT were acquired. After SIRT

RadiationPhysics and Astronomy
6
Article|60 citations·2018
Intratumoral heterogeneity characterized by pretreatment PET in non-small cell lung cancer patients predicts progression-free survival on EGFR tyrosine kinase inhibitor
Sehhoon Park, Seunggyun Ha, Se‐Hoon Lee, Jin Chul Paeng, Bhumsuk Keam, Tae Min Kim, Dong‐Wan Kim, Dae Seog Heo
SJR Q1PLoS ONEOA

Intratumoral heterogeneity has been suggested to be an important resistance mechanism leading to treatment failure. We hypothesized that radiologic images could be an alternative method for identification of tumor heterogeneity. We tested heterogeneity textural parameters on pretreatment FDG-PET/CT in order to assess the predictive value of target therapy. Recurred or metastatic non-small cell lung cancer (NSCLC) subjects with an activating EGFR mutation treated with either gefitinib or erlotini

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|58 citations·2010
Evaluation of Focal Cortical Dysplasia and Mixed Neuronal and Glial Tumors in Pediatric Epilepsy Patients Using18F-FDG and11C-Methionine PET
Ji Hoon Phi, Jin Chul Paeng, Hyo Sang Lee, Kyu‐Chang Wang, Byung-Kyu Cho, Ji-Yeoun Lee, Sung‐Hye Park, Joongyub Lee, Dong Soo Lee, Seung Ki Kim
SJR Q1Journal of Nuclear MedicineOA

Although (18)F-FDG plays a major role in the preoperative work-up of epilepsy surgery patients, it appears from this study that (18)F-FDG does not contribute to the differential diagnosis and that another tracer such as (11)C-methinine is required. (11)C-methinine PET results correlated well with the pathologic spectrum in pediatric lesional epilepsy patients.

Psychiatry and Mental healthMedicine
8
Article|55 citations·2015
Comparison of SPECT/CT and MRI in Diagnosing Symptomatic Lesions in Ankle and Foot Pain Patients: Diagnostic Performance and Relation to Lesion Type
Seunggyun Ha, Sung Hwan Hong, Jin Chul Paeng, Dong Yeon Lee, Dong Yeon Lee, Gi Jeong Cheon, Amitabh Arya, June-Key Chung, Dong Soo Lee, Dong Soo Lee, Keon Wook Kang
SJR Q1PLoS ONEOA

PURPOSE: The purpose of this study was to compare the diagnostic performance of SPECT/CT and MRI in patients with ankle and foot pain, with regard to the lesion types. MATERIALS AND METHODS: Fifty consecutive patients with ankle and foot pain, who underwent 99mTc-MDP SPECT/CT and MRI, were retrospectively enrolled in this study. Symptomatic lesions were determined based on clinical examination and response to treatment. On MRI and SPECT/CT, detected lesions were classified as bone, ligament/tend

Orthopedics and Sports MedicineMedicine
9
Article|40 citations·2015
Prognostic Value of Metabolic Tumor Volume on 11C-Methionine PET in Predicting Progression-Free Survival in High-Grade Glioma
Min Young Yoo, Jin Chul Paeng, Gi Jeong Cheon, Dong Soo Lee, June-Key Chung, E. Edmund Kim, Keon Wook Kang
SJR Q2Nuclear Medicine and Molecular Imaging
GeneticsMedicine
10
Article|37 citations·2010
Multimodal Molecular Imaging In Vivo
Jin Chul Paeng, Dong Soo Lee
The Open Nuclear Medicine JournalOA

In medical research and practice, imaging is now playing a crucial role. With rapidly developing molecular imaging, the role of in vivo imaging is expected to expand much more. In molecular imaging, one of the recent trends is multimodal imaging, which theoretically combines all the strengths of each imaging modality and consequently provides synergism. For this, many multimodal imaging probes have been developed so far. However, multimodal probe imaging is different from simple fusion images us

Biomedical EngineeringEngineering
11
Article|34 citations·2003
Lipiodol solution of 188Re-HDD as a new therapeutic agent for transhepatic arterial embolization in liver cancer: preclinical study in a rabbit liver cancer model.
Jin Chul Paeng, Jae Min Jeong, Chang Jin Yoon, Yun‐Sang Lee, Young‐Ger Suh, Jin Wook Chung, Jae Hyung Park, June‐Key Chung, Miwon Son, Myung Chul Lee
PubMed

UNLABELLED: It has been reported that lipiodol solution of (188)Re-labeled 2,2,9,9-tetramethyl-4,7-diaza-1,10-decanedithiol (TDD), an N(2)S(2) derivative, shows excellent targeting of liver cancer after transhepatic arterial embolization (TAE). However, its tumor retention is not high enough to treat liver cancer. Therefore, a new form of TDD, 4-hexadecyl-TDD (HDD), was developed to improve tumor retention by introducing a long alkyl chain. In this study, we compared the tumor retention properti

HepatologyMedicine
12
Review|34 citations·2021
Nuclear Imaging for Cardiac Amyloidosis: Bone Scan, SPECT/CT, and Amyloid-Targeting PET
Jin Chul Paeng, Joon Young Choi
SJR Q2Nuclear Medicine and Molecular ImagingOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
Article|31 citations·2011
Diagnostic Performance of Three-Phase Bone Scan for Complex Regional Pain Syndrome Type 1 with Optimally Modified Image Criteria
Hyun Woo Kwon, Jin Chul Paeng, Francis Sahngun Nahm, Seog Gyun Kim, Tanzeel Zehra, So Won Oh, Hyo Sang Lee, Keon Wook Kang, June-Key Chung, Myung Chul Lee, Dong Soo Lee
SJR Q2Nuclear Medicine and Molecular ImagingOA
Anesthesiology and Pain MedicineMedicine
14
Article|29 citations·2016
Total lesion glycolysis (TLG) as an imaging biomarker in metastatic colorectal cancer patients treated with regorafenib
Yoojoo Lim, Ji-In Bang, Sae‐Won Han, Jin Chul Paeng, Kyung-Hun Lee, Jee Hyun Kim, Gyeong Hoon Kang, Seung‐Yong Jeong, Kyu Joo Park, Tae‐You Kim
SJR Q1European Journal of Nuclear Medicine and Molecular Imaging
OncologyMedicine
15
Article|29 citations·2015
Total Lesion Glycolysis in Positron Emission Tomography Can Predict Gefitinib Outcomes in Non–Small-Cell Lung Cancer with Activating EGFR Mutation
Bhumsuk Keam, Soo Jin Lee, Tae Min Kim, Jin Chul Paeng, Se‐Hoon Lee, Dong‐Wan Kim, Yoon Kyung Jeon, Doo Hyun Chung, Keon Wook Kang, June-Key Chung, Dae Seog Heo
SJR Q1Journal of Thoracic OncologyOA
Pulmonary and Respiratory MedicineMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingHepatologyPulmonary and Respiratory MedicineEndocrinology, Diabetes and MetabolismSurgeryOncology

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