Jin Goo Lee
Yonsei University · 医学
研究室紹介
Professor Jin Goo Lee's research lab specializes in thoracic and cardiovascular surgery, with a strong focus on surgical oncology, particularly in lung and liver cancers. The lab investigates prognostic factors, treatment outcomes, and the biological mechanisms underlying resistance to therapy in patients with metastatic disease, including pulmonary metastasis from hepatocellular carcinoma and non-small cell lung cancer with ipsilateral metastases. The team also explores the role of physiological factors such as sarcopenia and autophagy in surgical outcomes and postoperative recovery. Their work integrates clinical data with molecular pathways, including hypoxia and autophagy, to improve patient stratification and treatment strategies.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Autophagy may play an important role in acquiring resistance to chemotherapy in lung cancer and hypoxia related pathway seems to be involved in autophagy induction.
Routine use of ECMO during LTx could improve early outcome and postoperative lung function without increased extracorporeal-related complication such as vascular and neurologic complications.
BACKGROUND: Advances in local treatments for hepatocellular carcinoma (HCC) have seen better prognosis. There were few studies on surgery for pulmonary metastasis from HCC controlled by local treatment. This study was conducted to analyze prognostic factors after surgery for pulmonary metastasis from HCC. METHODS: We reviewed 32 patients who underwent surgery for pulmonary metastasis from HCC and analyzed prognostic factors. RESULTS: HCC was controlled by surgery in 16 patients and by local trea
Although patients with thoracic sarcopenia seem to require a longer post-operative recovery time after LTx, this does not compromise their early outcomes. By contrast, patients with larger thoracic muscle volume (Q4) showed poorer survival times.
OBJECTIVE: Although designated as T4 or M1 in the current TNM classification system revised in 1997, non-small cell lung cancer with ipsilateral pulmonary metastases is treated as a locally advanced disease and reported survival rates are relatively good. We intended to analyze the prognosis of ipsilateral pulmonary metastases and validate current TNM classification system. METHODS: Data of 1213 surgically treated patients with non-small cell lung cancer from January 1990 to December 2004 were r
The overall survival of patients with resected stage I adenocarcinoma was adversely affected by incomplete fissure development. J. Surg. Oncol. 2016;114:848-852. © 2016 2016 Wiley Periodicals, Inc.
Mediastinal (N2) lymph node involvement is heterogeneous with huge variation in the extent and grouped together under stage IIIA. However, they showed a different survival even in the same stage. We tried to determine the prognostic implication of the multiple station N2 lymph node metastasis in stage IIIA N2 non-small cell lung cancer (NSCLC). The survival of stage IIIA N2 was analyzed according to the number of N2 station and their survival was compared with that of stage IIIB. In stage IIIA N
BACKGROUND: For diabetic patients with lung cancer, blood glucose levels and medications such as metformin and statins may influence survival. OBJECTIVES: This study aimed to determine prognostic survival factors for diabetic patients with resected non-small cell lung cancer. PATIENTS AND METHODS: Between January 2005 and December 2013, 301 patients with type 2 diabetes mellitus who underwent curative resection for non-small cell lung cancer were identified and reviewed retrospectively. RESULTS: