Jisoo Kim
Sungkyunkwan University · 医学
研究室紹介
Professor Jisoo Kim's research lab specializes in translational biomedical research with a focus on thyroid cancer, inflammatory mechanisms in gastrointestinal diseases, and molecular oncology. The lab investigates biomarkers such as TNF-alpha and MMP-9 in gastric and thyroid cancers, explores minimally invasive surgical techniques like robotic thyroidectomy, and develops diagnostic tools for indeterminate thyroid nodules using molecular markers like BRAF V600E. The work bridges clinical applications with molecular mechanisms, emphasizing precision diagnostics and therapeutic innovation in endocrine and gastrointestinal oncology.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Two arbitrary life distributions F and G can be ordered with respect to their Laplace transforms. We say is Laplace-smaller than for all s > 0. Interpretations of this ordering concept in reliability, operations research, and economics are described. General preservation properties are presented. Using these preservation results we derive useful inequalities and discuss their applications to M/G/ 1 queues, time series, coherent systems, shock models and cumulative damage models.
Given the lack of proven benefits and the clear evidence of morbidities, pCND cannot be recommended as a routine procedure. We suggest that CND be reserved for therapeutic situations.
Tumor necrosis factor (TNF)-alpha is one of the pro-inflammatory cytokines highly expressed in Helicobacter pylori that inhibits gastric acid secretion. In this study we determined the effect of silibinin on TNF-alpha-induced MMP-9 expression in gastric cancer cell lines. MMP-9 mRNA and protein expression was dose-dependently increased by TNF-alpha in SNU216 and SNU668 gastric cancer cells. On the other hand, TNF-alpha-induced MMP-9 expression was dose-dependently suppressed by silibinin. To ver
The bilateral axillo-breast approach (BABA) is one of the most popular contemporary remote-access thyroidectomy techniques. While the initial experiences with BABA endoscopic thyroidectomy (ET) were associated with some technical challenges and safety concerns, many limitations of the technique could now be substantially overcome by BABA robotic thyroidectomy (RT). In this review, the current literature evidences of BABA RT were analyzed. Data regarding the patient selection, the learning curve,
BACKGROUND: Although occult lymph node metastasis to the lateral neck compartment is common in papillary thyroid carcinoma, the incidence and patterns of lateral neck node metastasis in papillary carcinoma are not known. We hypothesized that sentinel lymph node biopsy (SLNB) with radioisotope in the detection of occult lateral neck node metastasis would be useful in characterizing metastasis in papillary carcinoma. METHODS: Ninety-four patients with papillary thyroid carcinoma were included from
Although ultrasonography (US)-guided fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic modality for evaluating thyroid nodules, 10% to 40% of FNAB samples yield indeterminate findings. The BRAF V600E mutation, a highly specific molecular marker for papillary thyroid carcinoma (PTC), well known for its prognostic value, has dubious diagnostic value because of its low sensitivity. Novel strategies are clearly needed to distinguish PTC, which represents the majority of thyroid ma
BACKGROUND: In the 2015 American Thyroid Association guidelines, either lobectomy or total thyroidectomy was recommended for thyroid cancer <4 cm without extrathyroidal extension (ETE) and lymph node (LN) metastasis. Therefore, the purpose of this study was to investigate factors predictive of bilaterality in papillary thyroid carcinoma (PTC) patients with tumor size <4 cm. METHODS: This study retrospectively reviewed 3296 conventional PTC patients who underwent total thyroidectomy with central
Endoscopic thyroidectomy is a safe and feasible alternative as compared with conventional open thyroidectomy in patients with a small thyroid cancer or a benign thyroid tumor. However, despite the many advantages of endoscopic surgery, it can result in unexpected complications. Recently, the authors experienced a case of follicular thyroid cancer recurrence that developed around the operative bed and along the port insertion site after endoscopic thyroidectomy for a large follicular neoplasm. Th