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Jiyoung Han

Yonsei University · 医学

研究室紹介

Professor Jiyoung Han's research lab specializes in biomaterials and regenerative dentistry, focusing on the development of advanced materials and surface engineering strategies to enhance implant integration, periodontal health, and tissue regeneration. The lab investigates the role of nano- and micro-scale surface topographies—particularly titanium dioxide (TiO₂) patterns—in improving fouling resistance and biocompatibility of medical membranes and implants. Key research directions include guided bone and tissue regeneration, sinus augmentation, ridge preservation, and the clinical application of bone grafts and collagen membranes in oral implantology. The lab also explores the interplay between host immune responses and biomaterials, particularly in the context of inflammatory conditions such as rheumatoid arthritis and periodontitis.

biomaterialsimplant integrationperiodontal regenerationsurface topographyguided tissue regeneration

Research Overview

Papers
257
Total Citations
5,150
Papers (5y)
42
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
42total
2022
2023
2024
2025
2026
Citations per year (5y)
113total
20222023202420252026

Selected Papers

15
1
Article|68 citations·2016
Nanoscale Pillar-Enhanced Tribological Surfaces as Antifouling Membranes
Wansuk Choi, Edwin P. Chan, Jong‐Hyun Park, Won-Gi Ahn, Hyun Wook Jung, Seungkwan Hong, Jong Suk Lee, Ji‐Young Han, Sangpil Park, Doo-Hyun Ko, Jung‐Hyun Lee, Jung‐Hyun Lee
SJR Q1ACS Applied Materials & Interfaces

We present a nonconventional membrane surface modification approach that utilizes surface topography to manipulate the tribology of foulant accumulation on water desalination membranes via imprinting of submicron titanium dioxide (TiO 2 ) pillar patterns onto the molecularly structured, flat membrane surface. This versatile approach overcomes the constraint of the conventional approach relying on interfacial polymerization that inevitably leads to the formation of ill-defined surface topography.

Water Science and TechnologyEnvironmental Science
2
Review|64 citations·2012
Effect of anti-rheumatic agents on periodontal parameters and biomarkers of inflammation: a systematic review and meta-analysis
Ji‐Young Han, Mark A. Reynolds
SJR Q1Journal of Periodontal & Implant ScienceOA

There are limited data, however, to suggest that anti-TNF-α agents can reduce local production of inflammatory cytokines and periodontal inflammation in RA patients with periodontitis.

RheumatologyMedicine
3
Article|61 citations·2015
A comparative study of combined periodontal and orthodontic treatment with fixed appliances and clear aligners in patients with periodontitis
Ji‐Young Han
SJR Q1Journal of Periodontal & Implant ScienceOA

After orthodontic treatment, clinical parameters were improved in the FA and CAT groups with meticulous oral hygiene education and plaque control. Regarding plaque index and gingival index, no significant differences were found between these two groups. We suggest that combined periodontal and orthodontic treatment can improve patients' periodontal health irrespective of orthodontic techniques.

OrthodonticsDentistry
4
Article|58 citations·2019
Factors influencing long‐term survival rates of implants placed simultaneously with lateral maxillary sinus floor augmentation: A 6‐ to 20‐year retrospective study
Won‐Bae Park, Kyung Lhi Kang, Ji‐Young Han
SJR Q1Clinical Oral Implants Research

OBJECTIVES: To evaluate the long-term influence of residual bone height (RBH), sinus membrane perforation and the presence of voids on the survival of implants placed simultaneously with lateral maxillary sinus floor augmentation (MSFA). MATERIALS AND METHODS: A total of 207 patients (613 implants) who underwent MSFA from 1999 to 2003 and followed up until 2018 were included in this study. RBH and marginal bone loss were assessed using a series of panoramic and periapical radiographs. Cumulative

Oral SurgeryDentistry
5
Article|48 citations·2011
The effects of bone grafting material and a collagen membrane in the ridge splitting technique: an experimental study in dogs
Ji‐Young Han, Seung‐Il Shin, Yeek Herr, Young‐Hyuk Kwon, Jong‐Hyuk Chung
SJR Q1Clinical Oral Implants Research

Abstract Objectives: This study was designed to evaluate the effect of bone graft materials and collagen membranes in ridge splitting procedures with immediate implant placement using a dog model. Materials and methods: Mandibular premolars were extracted in five beagle dogs. After 3 months, ridge splitting and placement of three OsseoSpeed ™ implants were performed bilaterally. The gaps between the implants were allocated according to the following eight treatment modalities; Group 1(no graft),

Oral SurgeryDentistry
6
Article|44 citations·2011
Labial and lingual/palatal bone thickness of maxillary and mandibular anteriors in human cadavers in Koreans
Ji‐Young Han, Gyu Un Jung
SJR Q1Journal of Periodontal & Implant ScienceOA

PURPOSE: The aim of this study is to evaluate the buccal and lingual bone thickness in the anterior teeth and the relationship between bone thickness and the tissue biotype. METHODS: Three male and two female human cadaver heads (mean age, 55.4 years) were used in this study. First, the biotype of periodontium was evaluated and categorized into a thick or a thin group. Next, full thickness reflections of the mandible and the maxilla to expose the underlying bone for accurate measurements in the

Oral SurgeryDentistry
7
Article|36 citations·2015
Nitric Oxide Induction of Parkin Translocation in PTEN-induced Putative Kinase 1 (PINK1) Deficiency
Ji‐Young Han, Minji Kang, Kyung‐Hee Kim, Pyung‐Lim Han, Hyunseok Kim, Ji‐Young Ha, Jin H. Son
SJR Q1Journal of Biological ChemistryOA

The failure to trigger mitophagy is implicated in the pathogenesis of familial Parkinson disease that is caused by PINK1 or Parkin mutations. According to the prevailing PINK1-Parkin signaling model, mitophagy is promoted by the mitochondrial translocation of Parkin, an essential PINK1-dependent step that occurs via a previously unknown mechanism. Here we determined that critical concentrations of NO was sufficient to induce the mitochondrial translocation of Parkin even in PINK1 deficiency, wit

EpidemiologyMedicine
8
Article|25 citations·2009
Induction of IL-8 expression by Cordyceps militaris grown on germinated soybeans through lipid rafts formation and signaling pathways via ERK and JNK in A549 cells
Ji‐Young Han, Jintaek Im, Jung Nam Choi, Choong Hwan Lee, Hye Jin Park, Dong Ki Park, Cheol‐Heui Yun, Seung Hyun Han
SJR Q1Journal of Ethnopharmacology
PharmacologyMedicine
9
Article|21 citations·2021
Clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients: a retrospective study
Ji‐Young Han, Seo Hee Park, Joohyung Kim, Kyung‐Gyun Hwang, Chang‐Joo Park
SJR Q1Journal of Periodontal & Implant ScienceOA

Although fixed retainers were bonded in periodontitis patients, periodontal health was well maintained if supportive periodontal treatment with repeated oral hygiene education was provided. Nonetheless, fixed retainer failure occurred more frequently in patients who had stage III (grade B or C) periodontitis or a CI ≥1 at 12-month follow-up after bonding of fixed retainers.

PeriodonticsDentistry
10
Review|20 citations·2014
Mitochondrial Homeostasis Molecules: Regulation by a Trio of Recessive Parkinson’s Disease Genes
Ji‐Young Han, Ji‐Soo Kim, Jin H. Son
SJR Q2Experimental NeurobiologyOA

Mitochondria are small organelles that produce the majority of cellular energy as ATP. Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease (PD), and rare familial forms of PD provide valuable insight into the pathogenic mechanism underlying mitochondrial impairment, even though the majority of PD cases are sporadic. The regulation of mitochondria is crucial for the maintenance of energy-demanding neuronal functions in the brain. Mitochondrial biogenesis and m

NeurologyMedicine
11
Article|17 citations·2019
Long‐term outcomes of the implants accidentally protruding into nasal cavity extended to posterior maxilla due to inferior meatus pneumatization
Won‐Bae Park, Young‐Jin Kim, Kyung Lhi Kang, Hyun‐Chang Lim, Ji‐Young Han
SJR Q1Clinical Implant Dentistry and Related Research

BACKGROUND: There is limited information about inferior meatus pneumatization in terms of implant treatment for the posterior maxilla. PURPOSE: To demonstrate the clinical, radiologic, and nasal endoscopic outcomes of implants accidentally protruding into the nasal cavities with inferior meatus pneumatization in the posterior maxilla. MATERIALS AND METHODS: A total of 560 implants (324 patients) with transcrestal sinus augmentation in the posterior maxilla were screened. On panoramic radiographs

OtorhinolaryngologyMedicine
12
Article|17 citations·2002
Opening of Mitochondrial ATP--Sensitive Potassium Channels Evokes Oxygen Radical Generation in Rabbit Heart Slices
Ji‐Young Han, N. Kim, Juhee Park, Dae‐Hyun Seog, Joo Hj, E. Kim
SJR Q2The Journal of Biochemistry

The purpose of this study was to determine whether ATP-sensitive potassium channel (K(ATP) channel) activation generates oxygen free radicals in the rabbit heart. We assayed malondialdehyde (MDA) in rabbit heart slices in vitro as an indicator of oxygen free radical generation. The K(ATP) channel openers, pinacidil and cromakalim, significantly increased MDA production in a concentration-dependent manner. MDA formation also increased linearly with incubation time in the presence of K(ATP) channe

Pathology and Forensic MedicineMedicine
13
Article|16 citations·2021
Long‐term effects of sinus membrane perforation on dental implants placed with transcrestal sinus floor elevation: A case–control study
Won‐Bae Park, Yeek Herr, Jong‐Hyuk Chung, Seung‐Il Shin, Ji‐Young Han, Hyun‐Chang Lim
SJR Q1Clinical Implant Dentistry and Related Research

BACKGROUND: There is a little comparative data on implants placed transcrestally with/without sinus membrane (SM) perforation. PURPOSE: To compare the clinical and radiological outcomes of implants with maxillary sinus perforation and those without SM perforation. MATERIALS AND METHODS: Among 560 transcrestally placed implants in 324 patients, the patients who underwent cone-beam computed tomographic radiography (CBCT) were included. The following groups were established: implants with SM perfor

Oral SurgeryDentistry
14
Article|9 citations·2023
Periodontal Phenotype Modification Using Subepithelial Connective Tissue Graft and Bone Graft in the Mandibular Anterior Teeth with Mucogingival Problems Following Orthodontic Treatment
Won‐Bae Park, Won‐Hee Park, Seung-Weon Lim, Ji‐Young Han
SJR Q2MedicinaOA

Among the complications of orthodontic treatment, mucogingival problems with gingival recession in the mandibular anterior teeth are challenging for clinicians. Mucogingival problems can lead to esthetic deficits, thermal hypersensitivity, tooth brushing pain, and complicated plaque control. Herein, we present a case of a 16-year-old female with gingival recession in the left mandibular central incisor after orthodontic treatment. The preoperative clinical findings showed a thin soft tissue biot

UrologyMedicine
15
Article|8 citations·2016
Nurses' Knowledge and Performance of Pain Management at a General hospital
Ji‐Young Han, Hyun-Sook Park, Mi-Jung Jin
SJR Q3Journal of Korean Academy of Fundamentals of NursingOA

Purpose: This study was done to describe level of knowledge and performance of pain management by nurses in general hospitals. Methods: The study was conducted from August 1 to 28, 2014 with 141 nurses from a general hospital in B city. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and Pearson correlation coefficient with SPSS 20.0. Results: Average correct response rate for knowledge was 62.7%, indicating poor knowledge of pain management. Mean score for knowledge of p

Leadership and ManagementNursing

Research Areas

Oral SurgeryPsychiatry and Mental healthSurgeryMolecular BiologyRheumatologyEpidemiology

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