K D Kim
Seoul National University · 医学
研究室紹介
Professor K. D. Kim's research lab specializes in translational oncology and biomedical data science, focusing on gynecological cancers such as cervical and ovarian cancer. The lab investigates prognostic factors like perineural invasion and metastatic patterns, explores molecular markers for survival prediction, and evaluates natural compounds for anticancer effects. Additionally, the lab pioneers the application of Common Data Models (CDM) and electronic health records for healthcare process mining, integrating clinical data with systems biology approaches. Their work bridges clinical oncology, molecular pathology, and health informatics to improve cancer diagnosis, treatment, and healthcare system optimization.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15The aim of this review is to examine the current status of gynecological cancer in China focusing on epidemiological data. Epidemiological data on gynecological cancer in China is sparse. Therefore, most of the data were estimated via extrapolation based on a few available datasets. Cervical cancer is relatively rare and the incidence and mortality rate are largely decreasing. However, in young women, the incidence and mortality rates are increasing. The overall and age-specific incidence rates
OBJECTIVE: THE OBJECTIVES OF THIS STUDY WERE TWOFOLD: to verify whether the type of metastasis (lymphatic vs. hematogenous) is a prognostic factor, and to identify molecular markers associated with survival in patients with disseminated cervical cancer. METHODS: Between April 1997 and May 2008, 30 patients with disseminated cervical cancer who had supraclavicular lymph node (N=13) or hematogenous metastases (N=17) were initially treated at our institute. We reviewed medical records to extract cl
Perineural invasion (PNI) has attracted attention as a new prognostic factor for cancer. We aimed to investigate the prognostic value of PNI in patients with cervical cancer. Clinical data of 185 patients with early-stage cervical cancer (stages IA2-IIA2) who underwent radical hysterectomy and pelvic lymphadenectomy between 2003 and 2011 were investigated. PNI was detected in 7% (13 of 18 cases) of patients. Moreover, 92% (12 of 13 cases) of patients with PNI received radiation therapy or concur
BACKGROUND AND OBJECTIVE: Recently, Electronic Health Records (EHR) are increasingly being converted to Common Data Models (CDMs), a database schema designed to provide standardized vocabularies to facilitate collaborative observational research. To date, however, rare attempts exist to leverage CDM data for healthcare process mining, a technique to derive process-related knowledge (e.g., process model) from event logs. This paper presents a method to extract, construct, and analyze event logs f
Abstract Background Ovarian cancer therapy generally involves systemic chemotherapy with anticancer drugs; however, chemotherapy with a platinum-based drug has often been shown to cause adverse reactions and drug resistance in ovarian cancer patients. Evodia rutaecarpa (ER) reportedly shows anticancer activity against various types of cancer cells. However, the effects of ER have not yet been fully uncovered in ovarian cancer. Methods In the present study, we investigated the anticancer effects
In this work the gas evolution behavior and the fining ability of the alkali‐free alkaline earth aluminoborosilicate glass batches doped with As 2 O 5 or SnO 2 were examined, and the redox behavior of As and Sn ion in the corresponding fined melts was investigated by square wave voltammetry. The evolved gas analysis showed a distinct difference at begin temperature of O 2 emission and in evolved O 2 volume between glass batches doped with As 2 O 5 and SnO 2 . One peak due to reduction of As 5+ t
In this review, we summarized nine major clinical advances in gynecology which occurred in 2009. For cervical cancer, the role of human papillomavirus (HPV) test as a screening test, the efficacy of HPV vaccine for middle-aged women, randomized controlled trial (RCT) regarding concurrent chemoradiation using gemcitabine plus cisplatin, and the efficacy of pazopanib for metastatic or recurrent disease were chosen. For endometrial cancer, the necessity of systematic pelvic lymphadenectomy in early
PURPOSE: To investigate whether the use of an activity tracker with feedback increases physical activity and is safe in patients who underwent a midline laparotomy for gynecologic disorders. METHODS: Patients who were planned to undergo a midline laparotomy for gynecologic diseases wore an activity tracker at baseline and from postoperative days 1-6. Patients in the experimental arm could monitor their step counts and were encouraged to achieve the individualized step-count goal daily. In contra
This study aimed to determine the factors influencing patients' choice of physician at the first visit through database analysis of a tertiary hospital in South Korea. We collected data on the first treatments performed by physicians who had treated patients for at least 3 consecutive years over 10 years (from 2003 to 2012) from the database of Seoul National University's affiliated tertiary hospital. Ultimately, we obtained data on 524,012 first treatments of 319,004 patients performed by 115 p
The device performance of nanoscale fin field-effect transistor (FinFET) was investigated by numerically solving coupled Poisson-Schrödinger equations in a self-consistent manner. The number of fins was varied in order to optimize the current driving capability of FinFET. The simulation results were compared with the experimental results in order to verify the validity of the proposed quantum mechanical approach. Device optimization was theoretically performed in order to suppress the short-chan