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Ki Young Lee

Kyung Hee University · 医学

研究室紹介

Professor Ki Young Lee's research lab specializes in interdisciplinary biomedical and materials science research, focusing on the mechanisms of disease-related protein mislocalization, the development of targeted cancer therapeutics, and the optimization of respiratory protection systems in occupational health. The lab integrates computational biology, molecular pharmacology, and industrial hygiene to address critical challenges in human health, from glioma biomarker discovery to novel anti-angiogenic drug design and respirator selection for infectious disease protection. Their work bridges fundamental biological insights with practical applications in clinical and occupational settings.

protein mislocalizationanti-angiogenic therapyrespiratory protectioncomputational biologycancer drug development

Research Overview

Papers
304
Total Citations
4,819
Papers (5y)
50
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
50total
2021
2022
2023
2024
2025
Citations per year (5y)
302total
20212022202320242025

Selected Papers

15
1
Article|127 citations·2018
A Functional Model of Workplace Envy and Job Performance: When do Employees Capitalize on Envy by Learning from Envied Targets?
Ki‐Young Lee, Michelle K. Duffy
SJR Q1Academy of Management Journal

We integrate the social functional view of emotions with recent developments in workplace envy research to develop and test a novel theoretical framework showing that envious employees can use their envy to promote self-enhancing actions rather than other-diminishing behaviors. We theorize that enviers’ core self-evaluations and friendship ties will attenuate the extent to which enviers undermine envied targets and promote the extent to which enviers actively learn from their envied targets thro

Social PsychologyPsychology
2
Article|118 citations·2000
Isolation and identification of a phenolic antioxidant from Aloe barbadensis
Ki‐Young Lee, Susan T. Weintraub, Byung Pal Yu
SJR Q1Free Radical Biology and Medicine
Plant ScienceAgricultural and Biological Sciences
3
Article|92 citations·2001
Characterization of LiNi0.85Co0.10M0.05O2 (M = Al, Fe) as a cathode material for lithium secondary batteries
Kyung K. Lee, Kyung K. Lee, Won‐Sub Yoon, Kwang‐Bum Kim, Ki‐Young Lee, Ki‐Young Lee, Seung‐Tae Hong
SJR Q1Journal of Power Sources
Electrical and Electronic EngineeringEngineering
4
Article|68 citations·2004
Respiratory Protection Against Mycobacterium tuberculosis: Quantitative Fit Test Outcomes for Five Type N95 Filtering-Facepiece Respirators
Ki‐Young Lee, Antonij Slavčev, Mark Nicas
SJR Q3Journal of Occupational and Environmental Hygiene

In preparing to fit test a large workforce, a respirator program manager needs to initially choose respirators that will fit the greatest proportion of employees and achieve the best fits. This article discusses our strategy in selecting respirators from an initial array of seven NIOSH-certified Type N95 filtering-facepiece devices for a respiratory protection program against Mycobacterium tuberculosis (M. tb) aerosol. The seven respirators were screened based on manufacturer-provided fit test d

Pulmonary and Respiratory MedicineMedicine
5
Article|66 citations·2010
Effects of Halide Anions to Absorb SO2in Ionic Liquids
Ki‐Young Lee, Chang Soo Kim, Honggon Kim, Minserk Cheong, D. MUKHERJEE, Kwang‐Deog Jung
SJR Q2Bulletin of the Korean Chemical Society

Halide anion effects of ILs were investigated using eight IL samples: [BMIm]Cl (1-butyl-3-methylimidazolium chloride; Aldrich 97%), [BMIm]Br (Aldrich, 97%), [BMIm]I (prepared), [EMIm]Cl (1-ethyl-3-methylimidazolium chloride; c-tri Korea, 98%), [HMIm]Cl (1-hexyl-3-methylimidazolium chloride; c-tri Korea, 98%), [OMIm]Cl (1-octyl-3-methylimidazolium chlo-ride; c-tri Korea, 98%), [BMpyri]Cl (1-butyl-4-methylpyridini-um chloride; prepared, 98%) and [BMpyrr]Cl (1-butyl-4-methyl-pyrrolidinium chloride;

CatalysisChemical Engineering
6
Article|61 citations·2004
Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model
Eunyoung Chun, Cheol Han, Jeong Hyeok Yoon, Tae Bo Sim, Yoon‐Keun Kim, Ki‐Young Lee
SJR Q1International Journal of CancerOA

Inhibition of angiogenesis is emerging as a promising strategy for the treatment of cancer. In our study reported here, the effects of 4 highly potent methionine aminopeptidase 2 (MetAP2) inhibitors, IDR-803, IDR-804, IDR-805 and CKD-732 (designed by structure-based molecular modeling), on angiogenesis and tumor growth were assessed. Concentrations of these inhibitors as low as 2.5 nM were able to inhibit the growth of human umbilical vein endothelial cells (HUVEC) by as much as 50%, arresting g

OncologyMedicine
7
Article|60 citations·2007
Single bolus of intravenous ketamine for anesthetic induction decreases oculocardiac reflex in children undergoing strabismus surgery
Seung Ho Choi, Sungmin Lee, Sun Ho Kim, Ji Hyoun Kim, Hyuck-Min Kwon, Young-Soo Shin, Ki‐Young Lee
SJR Q2Acta Anaesthesiologica ScandinavicaOA

BACKGROUND: Oculocardiac reflex (OCR) is a major complication of pediatric strabismus surgery. The aim of the present study was to determine whether a single bolus of intravenous (i.v.) ketamine for anesthetic induction can decrease OCR in children undergoing strabismus surgery. METHODS: One hundred and twenty healthy children undergoing strabismus surgery were allocated to three groups using double-blind randomization. Anesthesia was induced with propofol 3 mg/kg in Group P, ketamine 1 mg/kg in

Pathology and Forensic MedicineMedicine
8
Article|59 citations·2013
Proteome-wide discovery of mislocated proteins in cancer
Ki‐Young Lee, Kyunghee Byun, Won-Pyo Hong, Han‐Yu Chuang, Chan‐Gi Pack, Enkhjargal Bayarsaikhan, Sun Ha Paek, Hyosil Kim, Hye Young Shin, Trey Ideker, Bong‐Hee Lee
SJR Q1Genome ResearchOA

Several studies have sought systematically to identify protein subcellular locations, but an even larger task is to map which of these proteins conditionally relocates in disease (the mislocalizome). Here, we report an integrative computational framework for mapping conditional location and mislocation of proteins on a proteome-wide scale, called a conditional location predictor (CoLP). Using CoLP, we mapped the locations of over 10,000 proteins in normal human brain and in glioma. The predictio

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
letter|53 citations·1998
Relationship of cesarean delivery to lower birth weightâspecific neonatal mortality in singleton breech infants in the United States
Ki‐Young Lee
SJR Q1Obstetrics and Gynecology

Singleton live births with breech presentation delivered by cesarean had lower birth weight-specific neonatal mortality as compared with vaginal births.

Obstetrics and GynecologyMedicine
10
Article|50 citations·2001
Thermal behavior and the decomposition mechanism of electrochemically delithiated Li1−xNiO2
Kyung-Keun Lee, Kyung-Keun Lee, Won‐Sub Yoon, Kwang‐Bum Kim, Ki‐Young Lee, Ki‐Young Lee, Seung‐Tae Hong
SJR Q1Journal of Power Sources
Electrical and Electronic EngineeringEngineering
11
Article|50 citations·1994
Carbon monoxide and nitrogen dioxide exposures in indoor ice skating rinks
Ki‐Young Lee, Yukio Yanagisawa, John D. Spengler, S. Nakai
SJR Q1Journal of Sports Sciences

Exposures to carbon monoxide (CO) and nitrogen dioxide (NO2) were determined in seven enclosed ice skating rinks and an outdoor rink. The uptake of CO was also determined by the difference in alveolar CO concentration of the non-smoking hockey players before and after games. Carbon monoxide concentrations in enclosed rinks ranged from 4 to 117 ppm and NO2 concentrations from 342 to 2729 ppb for 2 h hockey games. The CO uptakes were linearly related to the ambient CO concentrations. Alveolar CO o

Public Health, Environmental and Occupational HealthMedicine
12
Article|38 citations·2019
Minimally invasive multilevel lateral lumbar interbody fusion with posterior column osteotomy compared with pedicle subtraction osteotomy for adult spinal deformity
Ki Young Lee, Jung‐Hee Lee, Kyung‐Chung Kang, Sung Joon Shin, Won Ju Shin, Sang Kyu Im, Moon Su Park
SJR Q1The Spine Journal
SurgeryMedicine
13
Article|36 citations·2020
Strategy for obtaining solid fusion at L5–S1 in adult spinal deformity: risk factor analysis for nonunion at L5–S1
Ki Young Lee, Jung‐Hee Lee, Kyung‐Chung Kang, Sung Joon Shin, Won Ju Shin, Sang‐Kyu Im, Joon Hong Park
SJR Q1Journal of Neurosurgery SpineOA

OBJECTIVE: Maintaining lumbosacral (LS) arthrodesis and global sagittal balance after long fusion to the sacrum remains an important issue in the surgical treatment for adult spinal deformity (ASD). The importance and usefulness of LS fixation have been documented, but the optimal surgical long fusion to the sacrum remains a matter for debate. Therefore, the authors performed a retrospective study to evaluate fusion on CT scans and the risk factors for LS pseudarthrosis (nonunion) after long fus

SurgeryMedicine
14
Article|35 citations·2020
Proximal Junctional Kyphosis in Degenerative Sagittal Deformity After Under- and Overcorrection of Lumbar Lordosis
Sang‐Kyu Im, Jung‐Hee Lee, Kyung‐Chung Kang, Sung Joon Shin, Ki Young Lee, Jong Jun Park, Man Ho Kim
SJR Q1Spine

STUDY DESIGN: Retrospective study. OBJECTIVE: To analyze proximal junctional kyphosis (PJK) occurrence and surgical outcomes according to degree of lumbar lordosis (LL) correction relative to pelvic incidence (PI). In addition, risk factors of PJK including LL and sagittal vertical axis (SVA) correction were investigated. SUMMARY OF BACKGROUND DATA: PJK is a common complication after adult spinal deformity surgery, and many factors are known to be associated with PJK. However, the effect of degr

SurgeryMedicine
15
Article|33 citations·2009
Coupling of Semiconductor Nanowires with Neurons and Their Interfacial Structure
Ki‐Young Lee, Sojung Shim, Il-Soo Kim, Hwangyou Oh, Sunoh Kim, Jae-Pyeong Ahn, Sang Han Park, Hyewhon Rhim, Heon‐Jin Choi
SJR Q1Nanoscale Research LettersOA

We report on the compatibility of various nanowires with hippocampal neurons and the structural study of the neuron-nanowire interface. Si, Ge, SiGe, and GaN nanowires are compatible with hippocampal neurons due to their native oxide, but ZnO nanowires are toxic to neuron due to a release of Zn ion. The interfaces of fixed Si nanowire and hippocampal neuron, cross-sectional samples, were prepared by focused ion beam and observed by transmission electron microscopy. The results showed that the pr

Biomedical EngineeringEngineering

Research Areas

SurgeryAnesthesiology and Pain MedicineCardiology and Cardiovascular MedicineMolecular BiologyPharmacologyDermatology

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