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Seo Tae Seok

Kyung Hee University · 工学

研究室紹介

Professor Seo Tae Seok's research lab specializes in the development and application of advanced carbon-based nanomaterials, particularly graphene and its derivatives, for environmental remediation, biomedical sensing, and next-generation DNA sequencing technologies. The lab focuses on innovative fabrication methods such as centrifugal vacuum evaporation to create 3D graphene sponges and free-standing films with tunable structures and functionalities. A key research direction involves leveraging the unique optical and surface properties of graphene quantum dots and photocleavable fluorescent nucleotides for high-sensitivity biosensors and sequencing-by-synthesis platforms. The lab also pioneers integrated microfluidic devices for rapid, automated detection of foodborne pathogens, demonstrating strong interdisciplinary integration of materials science, nanotechnology, and bioengineering.

graphene spongesDNA sequencingnanomaterialsbiosensorsmicrofluidics

Research Overview

Papers
230
Total Citations
5,445
Papers (5y)
40
Primary Field
工学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
40total
2022
2023
2024
2025
2026
Citations per year (5y)
282total
20222023202420252026

Selected Papers

15
1
Article|664 citations·2011
Three-Dimensional Graphene Oxide Nanostructure for Fast and Efficient Water-Soluble Dye Removal
Fei Liu, Soyi Chung, Gahee Oh, Tae Seok Seo
SJR Q1ACS Applied Materials & Interfaces

In this study, we demonstrated the potential of graphene nanomaterials as environmental pollutant adsorbents by utilizing the characteristics of ultralarge surface area and strong π-π interaction on the surface. We generated a three-dimensional (3D) graphene oxide sponge (GO sponge) from a GO suspension through a simple centrifugal vacuum evaporation method, and used them to remove both the methylene blue (MB) and methyl violet (MV) dyes which are main contaminants from the dye manufacturing and

Materials ChemistryMaterials Science
2
Article|629 citations·2013
Facile Synthetic Method for Pristine Graphene Quantum Dots and Graphene Oxide Quantum Dots: Origin of Blue and Green Luminescence
Fei Liu, Min‐Ho Jang, Hyun Dong Ha, Je‐Hyung Kim, Yong‐Hoon Cho, Tae Seok Seo
SJR Q1Advanced Materials

Pristine graphene quantum dots and graphene oxide quantum dots are synthesized by chemical exfoliation from the graphite nanoparticles with high uniformity in terms of shape (circle), size (less than 4 nm), and thickness (monolayer). The origin of the blue and green photoluminescence of GQDs and GOQDs is attributed to intrinsic and extrinsic energy states, respectively.

Materials ChemistryMaterials Science
3
Article|272 citations·2010
A Controllable Self‐Assembly Method for Large‐Scale Synthesis of Graphene Sponges and Free‐Standing Graphene Films
Liu Fei, Tae Seok Seo
SJR Q1Advanced Functional Materials

Abstract A simple method to prepare large‐scale graphene sponges and free‐standing graphene films using a speed vacuum concentrator is presented. During the centrifugal evaporation process, the graphene oxide (GO) sheets in the aqueous suspension are assembled to generate network‐linked GO sponges or a series of multilayer GO films, depending on the temperature of a centrifugal vacuum chamber. While sponge‐like bulk GO materials (GO sponges) are produced at 40 °C, uniform free‐standing GO films

Materials ChemistryMaterials Science
4
Article|254 citations·2010
Graphene oxide arrays for detecting specific DNA hybridization by fluorescence resonance energy transfer
Fei Liu, Jong Young Choi, Tae Seok Seo
SJR Q1Biosensors and Bioelectronics
Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
Article|234 citations·2016
An integrated rotary microfluidic system with DNA extraction, loop-mediated isothermal amplification, and lateral flow strip based detection for point-of-care pathogen diagnostics
Byung Hyun Park, Seung Jun Oh, Jae Hwan Jung, Goro Choi, Ji Hyun Seo, Do Hyun Kim, Eun Yeol Lee, Tae Seok Seo
SJR Q1Biosensors and Bioelectronics
Biomedical EngineeringEngineering
6
Article|126 citations·2016
Fully automated and colorimetric foodborne pathogen detection on an integrated centrifugal microfluidic device
Seung Jun Oh, Byung Hyun Park, Goro Choi, Ji Hyun Seo, Jae Hwan Jung, Jong Seob Choi, Do Hyun Kim, Tae Seok Seo
SJR Q1Lab on a Chip

This work describes fully automated and colorimetric foodborne pathogen detection on an integrated centrifugal microfluidic device, which is called a lab-on-a-disc. All the processes for molecular diagnostics including DNA extraction and purification, DNA amplification and amplicon detection were integrated on a single disc. Silica microbeads incorporated in the disc enabled extraction and purification of bacterial genomic DNA from bacteria-contaminated milk samples. We targeted four kinds of fo

Biomedical EngineeringEngineering
7
Article|122 citations·2005
Four-color DNA sequencing by synthesis on a chip using photocleavable fluorescent nucleotides
Tae Seok Seo, Xiaopeng Bai, Dae Hyun Kim, Qinglin Meng, Shundi Shi, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, Jingyue Ju
SJR Q1Proceedings of the National Academy of SciencesOA

We report four-color DNA sequencing by synthesis (SBS) on a chip, using four photocleavable fluorescent nucleotide analogues (dGTP-PC-Bodipy-FL-510, dUTP-PC-R6G, dATP-PC-ROX, and dCTP-PC-Bodipy-650) (PC, photocleavable; Bodipy, 4,4-difluoro-4-bora-3alpha,4alpha-diaza-s-indacene; ROX, 6-carboxy-X-rhodamine; R6G, 6-carboxyrhodamine-6G). Each nucleotide analogue consists of a different fluorophore attached to the 5 position of the pyrimidines and the 7 position of the purines through a photocleavab

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|116 citations·2004
Photocleavable fluorescent nucleotides for DNA sequencing on a chip constructed by site-specific coupling chemistry
Tae Seok Seo, Xiaopeng Bai, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, Jingyue Ju
SJR Q1Proceedings of the National Academy of SciencesOA

DNA sequencing by synthesis on a solid surface offers new paradigms to overcome limitations of electrophoresis-based sequencing methods. Here we report DNA sequencing by synthesis using photocleavable (PC) fluorescent nucleotides [dUTP-PC-4,4-difluoro-4-bora-3 alpha,4 alpha-diaza-s-indacene (Bodipy)-FL-510, dCTP-PC-Bodipy-650, and dUTP-PC-6-carboxy-X-rhodamine (ROX)] on a glass chip constructed by 1,3-dipolar azide-alkyne cycloaddition coupling chemistry. Each nucleotide analogue consists of a d

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|115 citations·2013
Three-dimensional graphene micropillar based electrochemical sensor for phenol detection
Fei Liu, Yunxian Piao, Jong Seob Choi, Tae Seok Seo
SJR Q1Biosensors and Bioelectronics
Electrical and Electronic EngineeringEngineering
10
Article|111 citations·2010
Fabrication of Free-Standing Multilayered Graphene and Poly(3,4-ethylenedioxythiophene) Composite Films with Enhanced Conductive and Mechanical Properties
Ki Seok Choi, Fei Liu, Jong Seob Choi, Tae Seok Seo
SJR Q1Langmuir

Poly(3,4-ethylenedioxythiophene) (PEDOT)-based film has relatively high conductivity, flexibility, and transmittance. However, the improvement for mechanical strength and conductivity is still required to be adopted for commercial applications. Graphene, a one atom thick planar sheet of sp(2)-bonded carbon atoms, is considered as an ideal nanocomposite material for these purposes. In this study, we have developed PEDOT and graphene composite films, two-layered graphene/PEDOT and three-layered gr

Polymers and PlasticsMaterials Science
11
Article|107 citations·2011
Graphene-based electrochemical biosensor for pathogenic virus detection
Fei Liu, Ki Seok Choi, Tae Jung Park, Sang Yup Lee, Tae Seok Seo
SJR Q1BioChip Journal
Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
Article|100 citations·2010
DNA mediated water-dispersible graphene fabrication and gold nanoparticle-graphene hybrid
Fei Liu, Jong Young Choi, Tae Seok Seo
SJR Q1Chemical Communications

Water dispersible single- and bilayered graphene sheets are produced by a direct exfoliation from graphite flakes in the presence of pyrene-labeled single stranded DNAs, and the immobilized DNA on the graphene surface is further hybridized with a gold nanoparticle labeled complementary DNA to generate gold nanoparticle-graphene nanocomposites.

Materials ChemistryMaterials Science
13
Article|93 citations·2016
A centrifugal direct recombinase polymerase amplification (direct-RPA) microdevice for multiplex and real-time identification of food poisoning bacteria
Goro Choi, Jae Hwan Jung, Byung Hyun Park, Seung Jun Oh, Ji Hyun Seo, Jong Seob Choi, Do Hyun Kim, Tae Seok Seo
SJR Q1Lab on a Chip

In this study, we developed a centrifugal direct recombinase polymerase amplification (direct-RPA) microdevice for multiplex and real-time identification of food poisoning bacteria contaminated milk samples. The microdevice was designed to contain identical triplicate functional units and each unit has four reaction chambers, thereby making it possible to perform twelve direct-RPA reactions simultaneously. The integrated microdevice consisted of two layers: RPA reagents were injected in the top

Biomedical EngineeringEngineering
14
Article|87 citations·2013
Micropatterned reduced graphene oxide based field-effect transistor for real-time virus detection
Fei Liu, Yo Han Kim, Doo Sung Cheon, Tae Seok Seo
SJR Q1Sensors and Actuators B Chemical
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Article|86 citations·2019
Point-of-care genetic analysis for multiplex pathogenic bacteria on a fully integrated centrifugal microdevice with a large-volume sample
Hau Van Nguyen, Van Dan Nguyen, Eun Yeol Lee, Tae Seok Seo
SJR Q1Biosensors and Bioelectronics
Biomedical EngineeringEngineering

Research Areas

Biomedical EngineeringMolecular BiologyMaterials ChemistryElectrical and Electronic EngineeringEpidemiologySurgery

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