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Seseon Kim

Yonsei University · 医学

研究室紹介

Professor Seseon Kim's research lab specializes in head and neck oncology, with a primary focus on oropharyngeal and oral squamous cell carcinomas. The lab investigates the molecular mechanisms of tumorigenesis, particularly the role of human papillomavirus (HPV) in tonsillar cancer, and explores biomarkers such as p16, survivin, and VEGF in tumor progression. A key research direction involves advancing transoral robotic surgery (TORS) techniques for improved oncologic outcomes and functional recovery in patients with head and neck cancers.

transoral robotic surgeryHPV-related cancerhead and neck oncologytumor microenvironmentoncologic outcomes

Research Overview

Papers
259
Total Citations
3,358
Papers (5y)
128
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
128total
2021
2022
2023
2024
2025
Citations per year (5y)
430total
20212022202320242025

Selected Papers

15
1
Article|222 citations·2007
HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c‐myc during tumor formation
Se‐Heon Kim, Bon Seok Koo, Suki Kang, Kyeongmee Park, Haeryoung Kim, Kyung‐Yul Lee, Moo Joo Lee, Jong Man Kim, Eun Chang Choi, Nam Hoon Cho
SJR Q1International Journal of CancerOA

The prevalence of human papillomavirus (HPV) infection is high in the oropharyngeal mucosal regions, of which the tonsil is the most commonly affected. There may be a link between HPV and the pathogenesis of tonsillar cancer (TC), because of common anatomical characteristics between cervical and tonsillar cancer. We aimed to clarify whether HPV directly affects the oncogenesis and biologic behavior of TC by making a comparison between infection prevalence, physical status and viral loading numbe

OtorhinolaryngologyMedicine
2
Article|125 citations·2010
Feasiblity of transoral robotic hypopharyngectomy for early-stage hypopharyngeal carcinoma
Young Min Park, Won Shik Kim, Hyung Kwon Byeon, Armando De Virgilio, Jinsei Jung, Se‐Heon Kim
SJR Q1Oral OncologyOA
OtorhinolaryngologyMedicine
3
Article|118 citations·2013
Comparison of oncologic and functional outcomes after transoral robotic lateral oropharyngectomy versus conventional surgery for T1 to T3 tonsillar cancer
Sei Young Lee, Young Min Park, Hyung Kwon Byeon, Eun Chang Choi, Se‐Heon Kim
SJR Q1Head & NeckOA

BACKGROUND: We performed transoral robotic surgery (TORS) or conventional surgery via a transoral or mandibulotomy approach in patients with tonsillar cancer and prospectively analyzed the oncologic outcomes and functional recovery of the 3 groups. METHODS: Between May 2008 and October 2011, 57 patients were enrolled in this prospective study. RESULTS: Although there was no significant difference in the survival rate of the TORS group (100%) and the conventional surgery group (96.7%), a higher r

OtorhinolaryngologyMedicine
4
Article|94 citations·2012
Transoral robotic surgery for hypopharyngeal squamous cell carcinoma: 3-Year oncologic and functional analysis
Young Min Park, Won Shik Kim, Armando De Virgilio, So Yoon Lee, Jeong Hun Seol, Se‐Heon Kim
SJR Q1Oral Oncology
OtorhinolaryngologyMedicine
5
Article|88 citations·2006
Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression
Se‐Heon Kim, Nam Hoon Cho, Kyubo Kim, Jin Seok Lee, Bon Seok Koo, Jeong Hong Kim, Jung Hyun Chang, Eun Chang Choi
SJR Q1Journal of Surgical OncologyOA

BACKGROUND AND OBJECTIVES: In oral tongue cancer, the degree of tumor invasion has a significant effect on the prognosis. We hypothesized that the destruction of extracellular matrix and neovascularization are related to tumor infiltration mechanism. By studying the tissues of early stage oral tongue cancer patients, we are intending to clarify the invasion-related factors. MATERIALS AND METHODS: To demonstrate the invasion process in early T-stage oral tongue cancer, the expressions of extracel

Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|72 citations·2012
Oncological and functional outcomes of transoral robotic surgery for oropharyngeal cancer
Young Min Park, Won Shik Kim, Hyung Kwon Byeon, Sei Young Lee, Se‐Heon Kim
SJR Q1British Journal of Oral and Maxillofacial SurgeryOA
OtorhinolaryngologyMedicine
7
Article|61 citations·2009
Feasibility of transoral lateral oropharyngectomy using a robotic surgical system for tonsillar cancer
Young Min Park, Jeong Gwon Lee, Won Sang Lee, Eun Chang Choi, Sa Myung Chung, Se‐Heon Kim
SJR Q1Oral OncologyOA
OtorhinolaryngologyMedicine
8
Article|51 citations·2013
Parapharyngeal Space Surgery via a Transoral Approach Using a Robotic Surgical System: Transoral Robotic Surgery
Young Min Park, Armando De Virgilio, Won Shik Kim, Hyun Pil Chung, Se‐Heon Kim
SJR Q2Journal of Laparoendoscopic & Advanced Surgical TechniquesOA

PPS surgery via a transoral approach using a robotic surgical system is technically feasible and secures a better cosmetic outcome than the transcervical, transparotid, or transmandibular approach. This new surgical method is safe and effective for benign diseases of the PPS.

RheumatologyMedicine
9
Article|48 citations·2017
The long-term oncological and functional outcomes of transoral robotic surgery in patients with hypopharyngeal cancer
Yae Won Park, Chan Min Jung, Dongchul Cha, Se‐Heon Kim
SJR Q1Oral OncologyOA
OtorhinolaryngologyMedicine
10
Review|46 citations·2019
Comparative safety and effectiveness of transoral robotic surgery versus open surgery for oropharyngeal cancer: A systematic review and meta-analysis
Dong Ah Park, Min Jin Lee, Se‐Heon Kim, Seon Heui Lee
SJR Q1European Journal of Surgical OncologyOA
OtorhinolaryngologyMedicine
11
Article|44 citations·2013
Comparison study of transoral robotic surgery and radical open surgery for hypopharyngeal cancer
Young Min Park, Hyung Kwon Byeon, Hyun Pil Chung, Eun Chang Choi, Se‐Heon Kim
SJR Q2Acta Oto-LaryngologicaOA

In the TORS and radical surgery groups, the 3-year overall survival rate was 85% and 78%, respectively, and disease-free survival was 81% and 76%, respectively. Significant differences were not observed in the overall survival and disease-free survival rates. As regards postoperative functional recovery, the TORS group showed statistically better results for decannulation, swallowing, and hospitalization compared with the radical surgery group. On the University of Washington (UW)-QOL, the TORS

OtorhinolaryngologyMedicine
12
Article|38 citations·2005
Combination of mutated herpes simplex virus type 1 (G207 virus) with radiation for the treatment of squamous cell carcinoma of the head and neck
Se‐Heon Kim, Richard J. Wong, David A. Kooby, John F. Carew, Prasad S. Adusumilli, Snehal G. Patel, Jatin P. Shah, Yuman Fong
SJR Q1European Journal of CancerOA
GeneticsBiochemistry, Genetics and Molecular Biology
13
Article|36 citations·2017
Transoral robotic surgery-based therapy in patients with stage III-IV oropharyngeal squamous cell carcinoma
Young Min Park, Hye Ryun Kim, Byoung Chul Cho, Ki Chang Keum, Nam Hoon Cho, Se‐Heon Kim
SJR Q1Oral OncologyOA
OtorhinolaryngologyMedicine
14
Article|34 citations·2023
Single‐Port Versus Multiport da Vinci System for Transoral Robotic Surgery of Hypopharyngeal and Laryngeal Carcinoma
Claudio Sampieri, Francesca Pirola, Andrea Costantino, Dahee Kim, Jung J. Ho, Kyuin Lee, Armando De Virgilio, Young Min Park, Se‐Heon Kim
SJR Q1OtolaryngologyOA

OBJECTIVE: Da Vinci single port (SP) has been recently approved for transoral robotic surgery (TORS). Its characteristics make it particularly feasible for laryngeal and hypopharyngeal surgery. We report our experience comparing intra- and postoperative outcomes, technical advantages, and shortcomings of transoral laryngeal and hypopharyngeal resections performed with the da Vinci SP and the da Vinci Si/Xi systems. STUDY DESIGN: Retrospective database review. SETTING: Single academic tertiary ca

OtorhinolaryngologyMedicine
15
Article|28 citations·2017
A New Clinical Trial of Neoadjuvant Chemotherapy Combined With Transoral Robotic Surgery and Customized Adjuvant Therapy for Patients With T3 or T4 Oropharyngeal Cancer
Young Min Park, Chan Min Jung, Dongchul Cha, Dahee Kim, Hye Ryun Kim, Ki Chang Keum, Nam Hoon Cho, Se‐Heon Kim
SJR Q1Annals of Surgical OncologyOA
OtorhinolaryngologyMedicine

Research Areas

OtorhinolaryngologySurgeryOncologyGeneticsCancer ResearchMolecular Biology

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