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Sunny Lee

Korea University · 医学

研究室紹介

Professor Sunny Lee's research lab focuses on sustainable environmental solutions and biomedical applications of biochar and natural compounds. The lab investigates biochar's role in mitigating greenhouse gas emissions, enhancing soil organic carbon, and improving crop yields in agricultural systems, particularly in East Asian contexts. Additionally, the lab explores the therapeutic potential of cannabidiol and related compounds in cancer treatment, emphasizing mechanisms involving endoplasmic reticulum stress and apoptosis pathways. The integration of environmental science and translational medicine defines the lab’s interdisciplinary approach.

biochargreenhouse gas mitigationsoil organic carboncannabidiolcolorectal cancer

Research Overview

Papers
244
Total Citations
2,772
Papers (5y)
55
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
55total
2022
2023
2024
2025
2026
Citations per year (5y)
240total
20222023202420252026

Selected Papers

15
1
Article|49 citations·2022
Short-Term Effect of Biochar on Soil Organic Carbon Improvement and Nitrous Oxide Emission Reduction According to Different Soil Characteristics in Agricultural Land: A Laboratory Experiment
Jong-Mun Lee, Do-Gyun Park, Seong-Su Kang, Eun-Jung Choi, Hyo-Suk Gwon, Hyoungseok Lee, Sun-Il Lee
SJR Q1AgronomyOA

Biochar application has been considered as a promising solution to address the effects of modern agriculture on climate change. However, there is a lack of research on the biochar application of greenhouse gas emissions based on poor soils in Korean agricultural land. Therefore, this study aimed to evaluate the effects of biochar application according to different soil characteristics on soil organic carbon (SOC) improvement and greenhouse gas reduction. The incubation experiments were conducted

Soil ScienceAgricultural and Biological Sciences
2
Review|41 citations·2021
Biochar-induced reduction of N2O emission from East Asian soils under aerobic conditions: Review and data analysis
Sun-Il Lee, Hyun-Jin Park, Young-Jae Jeong, Bo-Seong Seo, Jin‐Hyeob Kwak, Hye In Yang, Xingkai Xu, Shuirong Tang, Weiguo Cheng, Sang-Sun Lim, Woo‐Jung Choi
SJR Q1Environmental PollutionOA

Global meta-analyses showed that biochar application can reduce N<sub>2</sub>O emission. However, no relevant review study is available for East Asian countries which are responsible for 70% of gaseous N losses from croplands globally. This review analyzed data of the biochar-induced N<sub>2</sub>O mitigation affected by experimental conditions, including experimental types, biochar types and application rates, soil properties, and chemical forms and application rates of N fertilizer for East As

Soil ScienceAgricultural and Biological Sciences
3
Article|40 citations·2019
Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer
Jung Lim Kim, Bo Ram Kim, Dae Yeong Kim, Yoon A Jeong, Soyeon Jeong, Yoo Jin Na, Seong Hye Park, Hye Kyeong Yun, Min Jee Jo, Bu Gyeom Kim, Han Do Kim, Dae‐Hyun Kim
SJR Q1CancersOA

, is a potential therapeutic agent for a variety of diseases such as inflammatory diseases, chronic neurodegenerative diseases, and cancers. Here, we found that the combination of cannabidiol and TNF-related apoptosis-inducing ligand (TRAIL) produces synergistic antitumor effects in vitro. However, this synergistic effect was not observed in normal colonic cells. The levels of ER stress-related proteins, including C/EBP homologous protein (CHOP) and phosphorylated protein kinase RNA-like ER kina

Cell BiologyBiochemistry, Genetics and Molecular Biology
4
Article|36 citations·2008
Laparoscopic Resection of a Hepatocellular Carcinoma Arising from an Ectopic Liver
U-Hyoung Seo, Hyun‐Joo Lee, Woo‐Sang Ryu, Jung‐Myun Kwak, Bong-Kyung Shin, Wan‐Bae Kim, Sun-Il Lee, Sung Soo Park, Jae Woong Choi, Seon Hahn Kim, Sang-Yong Choi, Young‐Jae Mok
SJR Q2Surgical Laparoscopy Endoscopy & Percutaneous Techniques

Ectopic livers are rarely seen intra-abdominal lesions. Ectopic hepatocellular carcinoma (HCC) can be defined as an HCC arising from hepatic parenchyma located in an extrahepatic organ or tissue. The authors report a case of a primary, well-differentiated HCC arising from ectopic liver tissue in the left subphrenic space at the upper portion of the gastrorenal ligament that was successfully treated by laparoscopic resection. A 59-year-old man was referred to our department for the management of

SurgeryMedicine
5
Article|30 citations·2023
Effects of Biochar on Methane Emissions and Crop Yields in East Asian Paddy Fields: A Regional Scale Meta-Analysis
Jong-Mun Lee, Hyun-Cheol Jeong, Hyo-Suk Gwon, Hyoungseok Lee, Hye-Ran Park, Gaeun Kim, Do-Gyun Park, Sun-Il Lee
SJR Q1SustainabilityOA

Biochar emerged as a potential solution to mitigating greenhouse gas emissions, though previous studies obtained variable results regarding its effects on methane (CH4) emissions and crop yields. Global meta-analyses were conducted regarding the effectiveness of biochar, though regional meta-analyses are still needed. We performed a meta-analysis of 43 published papers to obtain the central tendency of the response to biochar application in East Asian rice paddies. Biochar application significan

Global and Planetary ChangeEnvironmental Science
6
Article|24 citations·2007
Relationship between meat and cereal consumption and colorectal cancer in Korea and Japan
Sun‐Il Lee, Hong‐Young Moon, Jung‐Myun Kwak, Jin Kim, Byung‐Wook Min, Jun‐Won Um, Seon‐Han Kim
SJR Q1Journal of Gastroenterology and Hepatology

BACKGROUND AND AIM: The incidence of colorectal cancer in Asian countries is increasing. The change to a more westernized diet is known to be related to these increases, and there are reports on the relationship between meat consumption and colorectal cancer in Japan. The aim of this study was to investigate the relationship between dietary change and colorectal cancer in Korea and Japan. METHODS: The data of meat and cereal consumption in Japan (1950-2002) and Korea (1970-2003), and the data of

OncologyMedicine
7
Article|19 citations·2007
Formalin Application for the Treatment of Radiation-Induced Hemorrhagic Proctitis
Sun-Il Lee, Yoon-Ah Park, Seung-Kook Sohn
SJR Q2Yonsei Medical JournalOA

Radiation-induced hemorrhagic proctitis (RIHP) is a serious complication of pelvic irradiation, and a 4% formalin solution has been used for 20 years in treating this sequelae. The first case involving formalin application for treatment of RIHP in Korea was reported in 1996, but there are no additional studies beyond this date. Our study reviews the use of formalin instillation and selective application. The purpose of this study was to retrospectively evaluate the outcome of such treatments, be

OncologyMedicine
8
Article|17 citations·2014
Coal fly ash enhanced planted-floating bed performance in phosphorus-contaminated water treatment
Sun-Il Lee, Sang-Sun Lim, Kwang-Seung Lee, Woo-Kyun Park, JoungDu Shin, Kwang Sik Yoon, Han-Yong Kim, Woo‐Jung Choi
SJR Q1Ecological Engineering
Industrial and Manufacturing EngineeringEnvironmental Science
9
Article|15 citations·2011
Kinetic Responses of Soil Carbon Dioxide Emission to Increasing Urea Application Rate
Sun-Il Lee, Sang-Sun Lim, Kwang-Seung Lee, Jin‐Hyeob Kwak, Jae-Woon Jung, Hee-Myoung Ro, Woo‐Jung Choi
SJR Q4Korean Journal of Environmental Agriculture

BACKGROUND: Application of urea may increase <TEX>$CO_2$</TEX> emission from soils due both to <TEX>$CO_2$</TEX> generation from urea hydrolysis and fertilizer-induced decomposition of soil organic carbon (SOC). The objective of this study was to investigate the effects of increasing urea application on <TEX>$CO_2$</TEX> emission from soil and mineralization kinetics of indigenous SOC. METHODS AND RESULTS: Emission of <TEX>$CO_2$</TEX> from a soil amended with four different rates (0, 175, 350,

Soil ScienceAgricultural and Biological Sciences
10
Article|13 citations·2024
Effect of rice hull biochar treatment on net ecosystem carbon budget and greenhouse gas emissions in Chinese cabbage cultivation on infertile soil
Do-Gyun Park, Hyeon-Cheol Jeong, Eun-Bin Jang, Jong-Mun Lee, Hyoung-Seok Lee, Hye-Ran Park, Sun-Il Lee, Do-Gyun Park, Eun-Bin Jang, Taek–Keun Oh
SJR Q2Applied Biological ChemistryOA

Abstract Biochar, with its potential to enhance soil fertility, sequester carbon, boost crop yields and reduce greenhouse gas emissions, offers a solution. Addressing the challenges posed by climate change is crucial for food security and agriculture. However, its widespread adoption in agriculture remains in its infancy. This study assessed the effects of rice hull biochar on cabbage production and greenhouse gas emissions, especially nitrous oxide (N 2 O). A trial, employing a randomized block

Soil ScienceAgricultural and Biological Sciences
11
Article|11 citations·2021
Soil carbon storage in upland soils by biochar application in East Asia
Sun-Il Lee, Seong Soo Kang, Eun-Jung Choi, Hyo-Suk Gwon, Hyoungseok Lee, Jong-Mun Lee, Sang-Sun Lim, Woo-Jung Choi
SJR Q4Korean Journal of Environmental AgricultureOA

BACKGROUND: Biochar is a solid material converted from agricultural biomass such as crop residues and pruning branch through pyrolysis under limited oxygen supply.Biochar consists of non-degradable carbon (C) double bonds and aromatic ring that are not readily broken down by microbial degradation in the soils.Due to the recalcitrancy of C in biochar, biochar application to the soils is of help in enhancing soil carbon sequestration in arable lands that might be a strategy of agricultural sector

Soil ScienceAgricultural and Biological Sciences
12
Article|9 citations·2007
Local Recurrence after Laparoscopic Resection of T3 Rectal Cancer without Preoperative Chemoradiation and a Risk Group Analysis: An Asian Collaborative Study
Sun-Il Lee, Seon Hahn Kim, Hwei-Ming Wang, Gyu‐Seog Choi, MinHua Zheng, Masaki Fukunaga, Jun-Gi Kim, Wai Lun Law, Joe-Bin Chen
SJR Q1Journal of Gastrointestinal Surgery
OncologyMedicine
13
letter|9 citations·2013
The impact of ozone depletion on skin cancer incidence in Korea
Sun‐Il Lee, Neubert Ko, Sang Wook Son, Hyun-Joo Bae, Jongsik Ha, Haeyong Pak, Yongseung Shin
SJR Q1British Journal of Dermatology

Conflict of interest: none declared. Dear Editor, A worldwide depletion of the ozone layer has been observed over the past decade. Concern was heightened when evidence emerged that ozone losses (albeit smaller than those over Antarctica) were also taking place in the Arctic and over heavily populated mid‐latitudes in both the northern and southern hemispheres. The damage to the ozone layer has therefore increased human exposure to ultraviolet (UV) B radiation, and subsequently increased the morb

DermatologyMedicine
14
Article|6 citations·2018
Reduction of Carbon Dioxide and Nitrous Oxide Emissions through Various Biochars Application in the Upland
Sun-Il Lee, Gun-Yeob Kim, Eun-Jung Choi, Jong‐Sik Lee, Hyun-Cheol Jeong
Jornal of Korea Organic Resource Recycling Association
Building and ConstructionEngineering
15
Article|6 citations·2007
SPHINCTER‐PRESERVING OPERATIONS WITHOUT DEFUNCTIONING STOMA
Sun‐Il Lee, Seung‐Kook Sohn, Y.K. Park
SJR Q2ANZ Journal of SurgeryOA

Sphincter-preserving operations have increasingly been carried out during the last few decades; nevertheless, temporary defunctioning stoma is still being frequently used for low colorectal anastomosis (LCRA) with staplers and hand-sewn coloanal anastomosis (CAA). From 1994 to 2003, 131 consecutive patients with rectal cancer with tumours within 7 cm from the anal verge underwent LCRA or CAA without defunctioning stoma. Anastomotic complications and treatment were compared between the groups. Th

OncologyMedicine

Research Areas

OncologyEcology, Evolution, Behavior and SystematicsSoil ScienceMolecular BiologySurgeryPharmacology

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