WanHee Kim

Presents a uniform approach to various engineering problems, such as analysis and synthesis of electrical networks, sampled-data feedback, control systems, switching networks, and communications nets

This study investigates the feasibility of using an adipose-derived mesenchymal stem cell (ASC)-seeded acellular dermal matrix (ADM) along with low-level laser therapy (LLLT) to repair bone defect in athymic nude mice. Critical-sized calvarial defects were treated either with ADM, ADM/LLLT, ADM/ASCs, or ADM/ASCs/LLLT. In micro-computed tomography scans, the ADM/ASCs and the ADM/ASCs/LLLT groups showed remarkable bone formation after 14 days. Additionally, bone regeneration in the ADM/ASCs/LLLT g

Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele. Previous studies revealed a positive association between hyperlipidemia and gallstones in humans. However, the latter is still unclear in dogs with cholelithiasis. In this study, we examined the differences in leptin, leptin receptor, total cholesterol, and triglyceride levels between health

OBJECTIVE: To evaluate the feasibility of single-port retroperitoneoscopic adrenalectomy (SPRA) in dogs. STUDY DESIGN: A pilot experimental study. ANIMALS: Eight healthy beagle dogs. METHODS: SPRA was performed on the left and right sides (4 dogs each). Resection of the adrenal gland was performed through a SILS port using a retroperitoneal approach. Operative time was defined from skin incision to the completion of skin suture. Postoperative pain was evaluated by using 3 pain scores. Integrity

The purpose of this study is to evaluate the effect of acellular dermal matrix (ADM) as a delivery carrier of adipose-derived mesenchymal stem cells (ASCs) on bone regeneration in athymic murine calvarial bone defect. Paired-critical size defects in nude rat skull were made. The right-side defects received ASCs/ADM or only ADM, whereas the left-side defect was not treated. In 3D images, new bone formation in the ASCs/ADM group was apparent at 4 wk, but in the ADM group at 8 wk. At 4 and 8 wk, bo

Objective To develop and describe a laparoscopic retroperitoneal access technique, investigate working space establishment, and describe the surgical anatomy in the retroperitoneal space as an initial step for clinical application of retroperitoneal laparoscopy in dogs. Study Design Cadaveric and experimental study. Animals Cadaveric (n=8) and healthy (n=6) adult dogs. Methods The retroperitoneal access technique was developed in 3 cadavers based on the human technique and transperitoneal observ

BACKGROUND: Ectopic Cushing's syndrome (ECS) associated with malignant tumors, such as small cell lung carcinoma, bronchial carcinoids, and pheochromocytoma, has been reported in human medicine. However, ECS related to pheochromocytoma has not been reported in dogs. CASE PRESENTATION: An 11-year-old castrated, male Scottish terrier was diagnosed with a left adrenal mass. Cushing's syndrome was suspected based on clinical signs, including pot belly, polyuria, polydipsia, bilateral alopecia, recur

Accurate state-of-health (SoH) prediction of lithium-ion batteries (LiBs) is a critical step in LiBs health prognostics to ensure its reliable operation and safety. Recently, there has been an increase in graph neural network (GNN) adaptation across many fields including LiBs health prognostics, which have shown benefits of spatio-temporal-based neural networks over the traditional counterparts. However, many of these studies have been shown to rely on discharge profiles as part of their input f

Received signal strength indication method enables flexible positioning without additional hardware installation and modification from communication resources. The expectation value of distance is changed due to the shadow fading. The effects of shadow fading in indoor RSSI ranging and convergence with pedestrian dead reckoning by using Extended Kalman Filter are presented. The fusion of pedestrian dead reckoning and RSSI ranging simulation shows that the compensation Shadow Fading effect has sl

Since the discovery of klotho as an anti-aging gene, its association with tumors has been studied. Several previous studies have reported the down-expression of klotho in various human cancers, and much of its mechanism has been revealed. Nonetheless, the significance of klotho in canine mammary gland tumors is not yet known. This study aimed to determine whether klotho is expressed within normal canine mammary glands and whether the expression changes in benign and malignant tumors. Using immun

The hormone leptin is produced by mature adipocytes and plays an important role in regulating food intake and energy metabolism through its interaction with the leptin receptor. In addition to roles in obesity and obesity-related diseases, leptin has been reported to affect the components and secretion of bile in leptin-deficient mice. Furthermore, gallbladder diseases such as cholelithiasis are known to be associated with serum leptin concentrations in humans. We hypothesized that the canine ga

The plant defense responses to microbial infection are tightly regulated and integrated with the developmental program for optimal resources allocation. Notably, the defense- associated hormone salicylic acid (SA) acts as a promoter of flowering while several plant pathogens actively target the flowering signaling pathway to promote their virulence or dissemination. Ralstonia pseudosolanacearum inject tens of effectors in the host cells that collectively promote bacterial proliferation in plant

도시 내 상업지역의 지리적 분포 양상과 그에 영향을 미친 요인들에 대한 관심이 증대되고 있다. 본 연구에서는 상업집적지의 공간적 변화가 활발히 일어나는 홍대지역을 사례로 상업 집적지의 시공간적 변화 분석을 수행하였다. 분석에는 비교적짧은 기간에 발생한 상업 집적지의 공간적 범위 변화를 탐지하는 데에 적합성이 높은 유동인구 자료와 기존의 연구들에서 활용한요식업 현황 자료를 이용하였으며, 각각 2016 4월년부터 2017년 4월까지 세 개 시점의 분석 결과를 비교하였다. 인구유동 자료에기반을 둔 분석 결과, 홍대지역 상업 집적지의 공간적 범위가 점차 확장되었으며 특히 북측 방향과 남측 방향으로 크게 변화하였음을확인하였다. 요식업 현황 자료에서도 유사한 공간적 변화가 탐지되었으나, 변화량이 다소 적게 나타났다. 홍대지역과 신촌·이대거리, 망리단길은 상업 집적지 간의 연결성이 뚜렷하게 드러나지 않고 별개의 집적지를 형성한 것으로 나타났다. 종합적으로 홍대지역의 상업 집적지는 포화상태인 기존