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Wook-beom Pyeon

Ewha Womans University · 医学

研究室紹介

Professor Wook-beom Pyeon's research lab specializes in cardiovascular and hypertension-related epidemiology, with a focus on the long-term effects of antihypertensive medications on cancer risk, cardiac outcomes in non-ischemic cardiomyopathy, and the impact of environmental factors such as air pollution and temperature on acute myocardial infarction. The lab also investigates the complex interplay between antihypertensive therapy and infectious complications—particularly in the elderly—highlighting the clinical implications of drug-induced hemodynamic changes during severe infections. Their work leverages large-scale national health databases to refine risk stratification and optimize treatment strategies in hypertensive and cardiovascular patients.

hypertensioncardiovascular riskantihypertensive drugsenvironmental exposureepidemiology

Research Overview

Papers
202
Total Citations
6,294
Papers (5y)
43
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
43total
2022
2023
2024
2025
2026
Citations per year (5y)
225total
20222023202420252026

Selected Papers

15
1
Article|3,040 citations·2019
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
Hertzel C. Gerstein, Helen M. Colhoun, Gilles R. Dagenais, Rafael Díaz, Mark Lakshmanan, Prem Pais, Jeffrey L. Probstfield, Jeffrey S. Riesmeyer, Matthew C. Riddle, Lars Rydén, Denis Xavier, Charles Atisso
SJR Q1The LancetOA
Endocrinology, Diabetes and MetabolismMedicine
2
Article|629 citations·2019
Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial
Hertzel C. Gerstein, Helen M. Colhoun, Gilles R. Dagenais, Rafael Díaz, Mark Lakshmanan, Prem Pais, Jeffrey L. Probstfield, Fady T. Botros, Matthew C. Riddle, Lars Rydén, Denis Xavier, Charles Atisso
SJR Q1The LancetOA
Endocrinology, Diabetes and MetabolismMedicine
3
Review|340 citations·2013
The Prognostic Value of Pre-Operative and Post-Operative B-Type Natriuretic Peptides in Patients Undergoing Noncardiac Surgery
Reitze Rodseth, Bruce Biccard, Yannick Le Manach, Daniel I. Sessler, Giovanna Lurati Buse, Lehana Thabane, Robert C. Schutt, Daniel Bolliger, Lucio Cagini, Daniela Cardinale, Carol Chong, Rong Chu
SJR Q1Journal of the American College of CardiologyOA
Cardiology and Cardiovascular MedicineMedicine
4
Article|39 citations·2018
Prognostic implications of late gadolinium enhancement at the right ventricular insertion point in patients with non-ischemic dilated cardiomyopathy: A multicenter retrospective cohort study
Jeong‐Eun Yi, Junbeom Park, Hye‐Jeong Lee, Dong Geum Shin, Yookyung Kim, Minsuk Kim, Kihwan Kwon, Wook Bum Pyun, Young Jin Kim, Boyoung Joung
SJR Q1PLoS ONEOA

LGE confined to the RVIP among NICM patients did not significantly increase the risk of adverse cardiac events, and also showed a better outcome than the same extent of LGE located in the LV. Identification of this unique LGE distribution may help refine the current risk stratification.

SurgeryMedicine
5
Article|39 citations·2021
Antihypertensive Drugs and the Risk of Cancer: A Nationwide Cohort Study
In‐Jeong Cho, Jeong‐Hun Shin, Mi‐Hyang Jung, Chae Young Kang, Jinseub Hwang, Chang Hee Kwon, Woohyeun Kim, Dae‐Hee Kim, Chan Joo Lee, Si‐Hyuck Kang, Ju‐Hee Lee, Hack‐Lyoung Kim
SJR Q1Journal of Clinical MedicineOA

We sought to assess the association between common antihypertensive drugs and the risk of incident cancer in treated hypertensive patients. Using the Korean National Health Insurance Service database, the risk of cancer incidence was analyzed in patients with hypertension who were initially free of cancer and used the following antihypertensive drug classes: Angiotensin-converting enzyme inhibitors (ACEIs); angiotensin receptor blockers (ARBs); beta blockers (BBs); calcium channel blockers (CCBs

Cardiology and Cardiovascular MedicineMedicine
6
Review|15 citations·2020
Is the use of RAS inhibitors safe in the current era of COVID-19 pandemic?
on behalf of the Korean Society of Hypertension, Sungha Park, Hae‐Young Lee, Eun Joo Cho, Ki‐Chul Sung, Juhan Kim, Dae‐Hee Kim, Sang‐Hyun Ihm, Kwang‐Il Kim, Il Suk Sohn, Wook‐Jin Chung, Hyeon Chang Kim
SJR Q1Clinical HypertensionOA

Antihypertensive drugs are one of the most widely used pharmacologic agent in the world and it is predominantly used in the elderly subjects. Pneumonia is the most common cause of death in the extremely old subject. During infection and its complication such as sepsis, hypotension could be exacerbated by antihypertensive drugs because homeostasis mechanisms such as sodium balance, renin angiotensin aldosterone system and/or sympathetic nervous system can be mitigated by antihypertensive drug the

Infectious DiseasesMedicine
7
Article|14 citations·2021
Effect of Short-Term Exposure to Fine Particulate Matter and Temperature on Acute Myocardial Infarction in Korea
Jiyoung Shin, Jongmin Oh, In Sook Kang, Eun‐Hee Ha, Wook Bum Pyun
SJR Q2International Journal of Environmental Research and Public HealthOA

BACKGROUND/AIM: Previous studies have suggested that the short-term ambient air pollution and temperature are associated with myocardial infarction. In this study, we aimed to conduct a time-series analysis to assess the impact of fine particulate matter (PM2.5) and temperature on acute myocardial infarction (AMI) among adults over 20 years of age in Korea by using the data from the Korean National Health Information Database (KNHID). METHODS: The daily data of 192,567 AMI cases in Seoul were co

Health, Toxicology and MutagenesisEnvironmental Science
8
Article|12 citations·2021
Office Blood Pressure Range and Cardiovascular Events in Patients With Hypertension: A Nationwide Cohort Study in South Korea
Chang Hee Kwon, Woohyeun Kim, Jeong‐Hun Shin, Chan Joo Lee, Hyeon Chang Kim, Si‐Hyuck Kang, Mi‐Hyang Jung, Dae‐Hee Kim, Ju‐Hee Lee, Hack‐Lyoung Kim, Hyue Mee Kim, In‐Jeong Cho
SJR Q1Journal of the American Heart AssociationOA

Background It is unclear what office blood pressure (BP) is the optimal treatment target range in patients with hypertension. Methods and Results Using the Korean National Health Insurance Service database, we extracted the data on 479 359 patients with hypertension with available BP measurements and no history of cardiovascular events from 2002 to 2011. The study end point was major cardiovascular events (MACE), a composite of cardiovascular death, myocardial infarction, or stroke. This cohort

Cardiology and Cardiovascular MedicineMedicine
9
letter|5 citations·2018
Lifestyle Modification, the Effective but Neglected Strategy in Lowering Blood Pressure
Wook Bum Pyun
SJR Q2Korean Circulation JournalOA
Cardiology and Cardiovascular MedicineMedicine
10
editorial|5 citations·2020
Hypertension Control in Young Population: the Earlier, the Better
Wook Bum Pyun
SJR Q2Korean Circulation JournalOA
Cardiology and Cardiovascular MedicineMedicine
11
Article|2 citations·2007
The Differences of Acute Myocardial Infarction in Women in Clinical Characteristics and Treatment
Wook Bum Pyun
SJR Q2Korean Circulation Journal
Cardiology and Cardiovascular MedicineMedicine
12
Article|2 citations·2000
Carotid Artery Stenting in Patients With Takayasu's Arteritis:Early and long-term follow-up results
Wook Bum Pyun, Young Sup Yoon, Kyung Jin Park, So Young Kim, Seung Yun Cho, Won Heum Shim
Sunhwan'giOA

Takayasu's arteritis is a chronic inflammatory disease of unknown etiology involving the aorta, major branches of aorta, and pulmonary arteries and leads either stenosis and occlusion of the involved artery or aneurysm formation or both.The clinical course and prognosis are variable according to two major prognostic factors, ie, complications and the pattern of the past clinical course, as well as by ESR.Though the aggressive medical and surgical treatment are required for patients with a major

Pulmonary and Respiratory MedicineMedicine
13
Article|2 citations·2002
Primary Prevention of Cardiovascular Disease.
Wook Bum Pyun
Gajeong yihag hoeji
Cardiology and Cardiovascular MedicineMedicine
15
Article|1 citations·2008
Are Statins Beneficial for Patients With Heart Failure?
Wook Bum Pyun
SJR Q2Korean Circulation Journal

There is a tremendous amount of evidence about the beneficial roles of statins, as related to primary and secondary prevention, for patients with ischemic heart disease. Many cardiologists are prescribing these drugs to their patients regardless of the left ventricular systolic function, and especially for patients with old myocardial infarction. After the report on the post-hoc analysis of the Scandinavian Simvastatin Survival Study, there have been many reports about the roles of statins for t

SurgeryMedicine

Research Areas

Cardiology and Cardiovascular MedicineSurgeryPulmonary and Respiratory MedicineHealth, Toxicology and MutagenesisEndocrinology, Diabetes and MetabolismInfectious Diseases

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