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Yong Hwan Kim

Ulsan National Institute of Science and Technology · 医学

研究室紹介

Professor Yong Hwan Kim's research lab specializes in bioinspired materials and biocatalysis, focusing on the development of sustainable biotechnologies for environmental remediation, cosmetic applications, and renewable energy conversion. Key research directions include the engineering of stable and efficient enzymes—such as lignin peroxidase and formate dehydrogenase—for industrial use, the design of advanced biosensors using carbon nanotubes and nanomaterials, and the integration of biological systems with photoelectrochemical platforms to produce value-added chemicals from CO2. The lab also investigates the physiological impacts of metabolic health in obesity, linking molecular mechanisms to cardiovascular outcomes.

biocatalysisbiosensorslignin degradationCO2 conversionenzyme engineering

Research Overview

Papers
319
Total Citations
5,522
Papers (5y)
69
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
69total
2021
2022
2023
2024
2025
Citations per year (5y)
548total
20212022202320242025

Selected Papers

15
1
Article|203 citations·1975
Tetrodotoxin: Occurrence in Atelopid Frogs of Costa Rica
Yong H. Kim, George Bosworth Brown, Harry S. Mosher, Frederick A. Fuhrman
SJR Q1Science

The potent neurotoxin tetrodotoxin, which has previously been found in puffer fish of the order Tetraordontiformes, a goby (Gobius criniger), and the California newt (Taricha torosa), has now been identified in the skins of frogs of the genus Atelopus from Costa Rica.

Environmental ChemistryEnvironmental Science
2
Review|137 citations·2019
Clinical validity of saliva and novel technology for cancer detection
Karolina Elżbieta Kaczor‐Urbanowicz, Wei Fang, Shannon Liu Rao, Jinseok Kim, Heebum Shin, Jordan Cheng, Michael Tu, David T. Wong, Yong H. Kim
SJR Q1Biochimica et Biophysica Acta (BBA) - Reviews on CancerOA
SurgeryMedicine
3
Article|81 citations·2015
Electro-biocatalytic production of formate from carbon dioxide using an oxygen-stable whole cell biocatalyst
Hyojin Hwang, Young Joo Yeon, Sumi Lee, Hyunjun Choe, Min Gee Jang, Dae Haeng Cho, Sehkyu Park, Yong Hwan Kim
SJR Q1Bioresource Technology
Renewable Energy, Sustainability and the EnvironmentEnergy
4
Article|76 citations·2020
Two-stage bioconversion of carbon monoxide to biopolymers via formate as an intermediate
Ho Won Hwang, Jihee Yoon, Kyoungseon Min, Min‐Sik Kim, Seung-Jin Kim, Dae Haeng Cho, Susila Hadiyati, Jeong‐Geol Na, Min‐Kyu Oh, Yong Hwan Kim
SJR Q1Chemical Engineering JournalOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
Article|71 citations·2019
Recombinant lignin peroxidase-catalyzed decolorization of melanin using in-situ generated H2O2 for application in whitening cosmetics
Ho Joon Sung, Mohd Faheem Khan, Yong Hwan Kim
SJR Q1International Journal of Biological MacromoleculesOA

Lignin peroxidase has high potential as ingredient in skin whitening cosmetics due to its high redox potential to oxidize recalcitrant melanin. Currently crude mixtures of lignin peroxidase from fungal fermentation are usually applied to cosmetics due to the intrinsic difficulties of expression and purification. However, the present study focused on heterologous expression and purification of lignin peroxidase isozyme H8 (LiPH8) from Phanerochaete chrysosporium and was further used for melanin d

Cell BiologyBiochemistry, Genetics and Molecular Biology
6
Article|58 citations·2018
Electrochemical synthesis of formic acid from CO2 catalyzed by Shewanella oneidensis MR-1 whole-cell biocatalyst
Quang Anh Tuan Le, Hee Gon Kim, Yong Hwan Kim
SJR Q2Enzyme and Microbial TechnologyOA
Environmental EngineeringEnvironmental Science
7
Article|56 citations·2016
Sunlight-assisted, biocatalytic formate synthesis from CO2 and water using silicon-based photoelectrochemical cells
Eun Jin Son, Jong Wan Ko, Su Keun Kuk, Hyunjun Choe, Sumi Lee, Jae Hong Kim, Dong Heon Nam, Gyeong Min Ryu, Yong Hwan Kim, Chan Beum Park
SJR Q1Chemical Communications

We report on a silicon-based photoelectrochemical cell that integrates a formate dehydrogenase from Thiobacillus sp. (TsFDH) to convert CO2 to formate using water as an electron donor under visible light irradiation and an applied bias. Our current study suggests that the deliberate integration of biocatalysis to a light-harvesting platform could provide an opportunity to synthesize valuable chemicals with the use of earth-abundant materials and sustainable resources.

Renewable Energy, Sustainability and the EnvironmentEnergy
8
Article|54 citations·2011
Obesity phenotype and cardiovascular changes
Juri Park, Seong‐Hyop Kim, Goo‐Yeong Cho, Inkyung Baik, Nan Hee Kim, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Sang Yup Lim, Yong H. Kim, Hyun Kim, Seung K. Lee
SJR Q1Journal of Hypertension

Healthy obesity was associated with subtle changes in left ventricular structure and function. These data provide evidence that metabolically healthy phenotypes with excess weight may not be a benign condition.

Cardiology and Cardiovascular MedicineMedicine
9
Article|51 citations·2005
Synthesis of polycardanol from a renewable resource using a fungal peroxidase from Coprinus cinereus
Yong Hwan Kim, Keehoon Won, Jeong Mi Kwon, Hyun Seong Jeong, Seung Young Park, Eun Suk An, Bong Keun Song
Journal of Molecular Catalysis B Enzymatic
Plant ScienceAgricultural and Biological Sciences
10
Article|51 citations·2009
Oriented Immobilization of Antibody Fragments on Ni-Decorated Single-Walled Carbon Nanotube Devices
Young-Seop Lo, Dong Hyun Nam, Hye‐Mi So, Hyunju Chang, Jinhee Kim, Yong Hwan Kim, Jeong-O Lee
SJR Q1ACS Nano

We herein demonstrate that Ni-decorated single-walled carbon nanotube field effect transistors (SWNT-FETs) combined with antibody fragments can be used as effective biosensing platforms. Nanoscales Ni particles 20 to 60 nm in diameter were formed on the sidewalls of SWNT-FETs using an electrochemical method. Carcinoembryonic antigen (CEA)-binding single chain variable fragments (scFvs) with a hexahistidine tag [(his)(6)] were synthesized using genetic engineering, and ordered immobilization of a

Materials ChemistryMaterials Science
11
Article|46 citations·2018
In silico-designed lignin peroxidase from Phanerochaete chrysosporium shows enhanced acid stability for depolymerization of lignin
Le Thanh Mai Pham, Hogyun Seo, Kyung‐Jin Kim, Yong Hwan Kim
Biotechnology for BiofuelsOA

BACKGROUND: (LiPH8) demonstrates a high redox potential and can efficiently catalyze the oxidation of veratryl alcohol, as well as the degradation of recalcitrant lignin. However, native LiPH8 is unstable under acidic pH conditions. This characteristic is a barrier to lignin depolymerization, as repolymerization of phenolic products occurs simultaneously at neutral pH. Because repolymerization of phenolics is repressed at acidic pH, a highly acid-stable LiPH8 could accelerate the selective depol

Plant ScienceAgricultural and Biological Sciences
12
Article|45 citations·2018
Bioelectrochemical conversion of CO2 to value added product formate using engineered Methylobacterium extorquens
Jungho Jang, Byoung Wook Jeon, Yong Hwan Kim
SJR Q1Scientific ReportsOA

Abstract The conversion of carbon dioxide to formate is a fundamental step for building C1 chemical platforms. Methylobacterium extorquens AM1 was reported to show remarkable activity converting carbon dioxide into formate. Formate dehydrogenase 1 from M. extorquens AM1 (MeFDH1) was verified as the key responsible enzyme for the conversion of carbon dioxide to formate in this study. Using a 2% methanol concentration for induction, microbial harboring the recombinant MeFDH1 expressing plasmid pro

Process Chemistry and TechnologyChemical Engineering
13
Article|45 citations·2020
Lignin-fueled photoelectrochemical platform for light-driven redox biotransformation
Ding Wang, Sahng Ha Lee, Seunghyun Han, Jin‐Hyun Kim, Nguyen Vu Thien Trang, Kayoung Kim, Eun‐Gyu Choi, Passarut Boonmongkolras, Yang Woo Lee, Byungha Shin, Yong Hwan Kim, Chan Beum Park
SJR Q1Green Chemistry

A bias-free photoelectrochemical oxidation of lignin in a tandem photoanode/PV structure is coupled with bioelectrocatalytic reductions (<italic>e.g.</italic>, CO<sub>2</sub> to formate and α-ketoglutarate to <sc>l</sc>-glutamate).

Renewable Energy, Sustainability and the EnvironmentEnergy
14
Article|41 citations·2011
The Efficacy of Several Neuromuscular Monitoring Modes at the P6 Acupuncture Point in Preventing Postoperative Nausea and Vomiting
Yong H. Kim, Kyo Sang Kim, Hee Jun Lee, Jae Chul Shim, Sung Wook Yoon
SJR Q1Anesthesia & Analgesia

Tetanic stimulation applied to the P6 acupuncture point can reduce PONV after laparoscopic hysterectomy compared with ST stimulation of the ulnar nerve, resulting in a greater degree of patient satisfaction. None of the stimulations, ST, train-of-four, or double-burst, applied to the P6 acupuncture point significantly affected PONV.

SurgeryMedicine
15
Article|40 citations·1978
New selective oxidation of thiols to the corresponding thiolsulfonates with dinitrogen tetroxide: one pot syntheses of thiolsulfonates from thiols
Yong H. Kim, Kōichi Shinhama, Daikichi Fukushima, Shigeru Ōae
SJR Q3Tetrahedron Letters
Organic ChemistryChemistry

Research Areas

SurgeryMaterials ChemistryPathology and Forensic MedicineRenewable Energy, Sustainability and the EnvironmentBiomedical EngineeringElectrical and Electronic Engineering

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