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Yong Sun Choi

Yonsei University · 医学

研究室紹介

Professor Yong Sun Choi's research lab specializes in perioperative medicine, with a primary focus on optimizing postoperative pain management and improving surgical outcomes through multimodal analgesia and anesthetic strategies. The lab investigates pharmacological interventions—such as pregabalin, dexamethasone, and ramosetron—alongside regional anesthetic techniques like PENG and FICB blocks to reduce opioid use and enhance recovery after orthopedic and spinal surgeries. Additional research explores the impact of anesthetic agents and fluid management on systemic inflammation, coagulation, and outcomes in elderly and high-risk surgical patients. The lab emphasizes evidence-based, patient-centered approaches to minimize postoperative complications and improve functional recovery.

postoperative painmultimodal analgesiaregional anesthesiaelderly surgeryperioperative medicine

Research Overview

Papers
249
Total Citations
3,389
Papers (5y)
35
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
35total
2021
2022
2023
2024
2025
Citations per year (5y)
268total
20212022202320242025

Selected Papers

15
1
Article|142 citations·2011
Effect of remote ischemic preconditioning on renal dysfunction after complex valvular heart surgery: A randomized controlled trial
Yong Seon Choi, Jae‐Kwang Shim, Jong Chan Kim, Kyu-Sik Kang, Yong Han Seo, Ki-Ryang Ahn, Young Lan Kwak
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
Pathology and Forensic MedicineMedicine
2
Article|106 citations·2010
Effective Dose of Peri-operative Oral Pregabalin as an Adjunct to Multimodal Analgesic Regimen in Lumbar Spinal Fusion Surgery
Jong Chan Kim, Yong Seon Choi, Yu Seun Kim, Jae‐Kwang Shim, Ji Yeon Lee, Young Lan Kwak
SJR Q1SpineOA

In Brief Study Design. A prospective, randomized, controlled, and double-blind trial. Objective. To evaluate the effects of 2 different doses of perioperative pregabalin administration, twice on the day of surgery, on acute postoperative pain after spinal surgery. Summary of Background Data. Besides its well-established role on neuropathic pain, pregabalin seems to be a promising adjunct to multimodal analgesic regimen following surgery. No comprehensive data exist regarding the optimal dosage o

SurgeryMedicine
3
Article|91 citations·2013
Comparison of the Effects of Normal Saline Versus Plasmalyte on Acid-Base Balance During Living Donor Kidney Transplantation Using the Stewart and Base Excess Methods
So Yeon Kim, Kyu Ha Huh, Jeong Rim Lee, Shin Hyung Kim, S.H. Jeong, Yong Seon Choi
SJR Q3Transplantation ProceedingsOA
NephrologyMedicine
4
Article|81 citations·2022
Pericapsular Nerve Group (PENG) Block versus Supra-Inguinal Fascia Iliaca Compartment Block for Total Hip Arthroplasty: A Randomized Clinical Trial
Yong Seon Choi, Kwan Kyu Park, Bora Lee, Won Seok Nam, Do‐Hyeong Kim
SJR Q2Journal of Personalized MedicineOA

This study compared the effects of the pericapsular nerve group (PENG) block and supra-inguinal fascia iliaca compartment block (FICB) on postoperative analgesia and quadriceps strength following total hip arthroplasty under general anesthesia. A total of 58 patients were randomized to receive either PENG block (PENG group) or supra-inguinal FICB (FICB group) following anesthetic induction. The primary outcomes were the postoperative pain scores. Patients were randomized to receive either PENG b

SurgeryMedicine
5
Article|80 citations·2016
Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion
Yong Seon Choi, Ana Barbosa Marcondes de Mattos, Dan Shao, Tao Li, Miranda Nabben, Maengjo Kim, Wang Wang, Rong Tian, Stephen C. Kolwicz
SJR Q1Journal of Molecular and Cellular CardiologyOA
Cardiology and Cardiovascular MedicineMedicine
6
Article|75 citations·2018
Carotid ultrasound measurements for assessing fluid responsiveness in spontaneously breathing patients: corrected flow time and respirophasic variation in blood flow peak velocity
Do‐Hyeong Kim, Seokyung Shin, Namo Kim, Tae Yang Choi, Seung Ho Choi, Yong Seon Choi
SJR Q1British Journal of AnaesthesiaOA
SurgeryMedicine
7
Article|64 citations·2008
Effect of Ramosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Spine Surgery in Highly Susceptible Patients
Yong Seon Choi, Jae‐Kwang Shim, Do Heum Yoon, D. Jeon, Ji Yeon Lee, Young Lan Kwak
SJR Q1SpineOA

Ramosetron was superior to ondansetron in terms of preventing vomiting and reducing the severity of nausea related to fentanyl-based IV PCA, with less adverse events, in patients with high susceptibility, undergoing lumbar spine surgery.

SurgeryMedicine
8
Article|51 citations·2012
Combination of Pregabalin and Dexamethasone for Postoperative Pain and Functional Outcome in Patients Undergoing Lumbar Spinal Surgery
Yong Seon Choi, Jae‐Kwang Shim, Jong Wook Song, Jong Chan Kim, Young Chul Yoo, Young Lan Kwak
SJR Q1Clinical Journal of PainOA

OBJECTIVES: In this randomized-controlled study, we investigated the effects of combined administration of pregabalin and dexamethasone on postoperative pain and analgesic requirements, and functional outcome in patients who underwent lumbar spinal surgery. METHODS: One hundred eight patients were randomized to group C (placebo+placebo), group P (pregabalin + placebo), or group PD (pregabalin+dexamethasone). According to their allocated group, patients received placebo or pregabalin 150 mg every

SurgeryMedicine
9
Article|48 citations·2009
Pressure-controlled versus volume-controlled ventilation during one-lung ventilation in the prone position for robot-assisted esophagectomy
Yong Seon Choi, Jae‐Kwang Shim, Sungwon Na, Seung Bum Hong, Yong Woo Hong, Young Jun Oh
SJR Q1Surgical EndoscopyOA
SurgeryMedicine
10
Article|46 citations·2010
Comparing the effects of 5% albumin and 6% hydroxyethyl starch 130/0.4 on coagulation and inflammatory response when used as priming solutions for cardiopulmonary bypass.
Yong Seon Choi, Jae‐Kwang Shim, Seong Wook Hong, J C Kim, Young Lan Kwak
PubMed

AIM: This prospective, randomized and controlled trial compares the use of human albumin (HA) and hydroxyethyl starch (HES) 130/0.4 in the priming solution for a non-biocompatible cardiopulmonary bypass (CPB) circuit. The effects of each substance on coagulation, postoperative blood loss and pro-inflammatory activities were examined. METHODS: Thirty-six adult patients undergoing mitral valvular heart surgery were randomly assigned to either the HA or HES group; 500 mL of 5% HA or 6% HES 130/0.4

Critical Care and Intensive Care MedicineMedicine
11
Article|38 citations·2012
Ramosetron, dexamethasone, and their combination for the prevention of postoperative nausea and vomiting in women undergoing laparoscopic cholecystectomy
Youn Yi Jo, Jong Wha Lee, Jae‐Kwang Shim, Woo Kyung Lee, Yong Seon Choi
SJR Q1Surgical Endoscopy
SurgeryMedicine
12
Article|36 citations·2020
Effects of Anesthesia Techniques on Outcomes after Hip Fracture Surgery in Elderly Patients: A Prospective, Randomized, Controlled Trial
Seokyung Shin, Seung Hyun Kim, Kwan Kyu Park, Seon Ju Kim, Jae Chan Bae, Yong Seon Choi
SJR Q1Journal of Clinical MedicineOA

The superiority of distinct anesthesia methods for geriatric hip fracture surgery remains unclear. We evaluated high mobility group box-1 (HMGB1) and interleukin-6 (IL-6) with three different anesthesia methods in elderly patients undergoing hip fracture surgery. Routine blood test findings, postoperative morbidity, and mortality were assessed as secondary outcome. In total, 176 patients were randomized into desflurane (n = 60), propofol (n = 58), or spinal groups (n = 58) that received desflura

Cardiology and Cardiovascular MedicineMedicine
13
Article|36 citations·2009
Risk factors of atrial fibrillation following off-pump coronary artery bypass graft surgery: predictive value of C-reactive protein and transfusion requirement
Yong Seon Choi, Jae‐Kwang Shim, Seong Wook Hong, Dae‐Hee Kim, Jong Chan Kim, Young Lan Kwak
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

Prophylactic strategies aimed at AF reduction may also be considered especially in patients with increased transfusion requirement, which showed highest predictive value for postoperative AF.

Cardiology and Cardiovascular MedicineMedicine
14
Article|29 citations·2015
Effects of Alveolar Recruitment and Positive End-Expiratory Pressure on Oxygenation during One-Lung Ventilation in the Supine Position
Yong Seon Choi, Mi Kyung Bae, Shin Hyung Kim, Ji Eun Park, Soo Young Kim, Young Jun Oh
SJR Q2Yonsei Medical JournalOA

Recruitment of both lungs with subsequent PEEP before OLV improved arterial oxygenation and ventilatory efficiency during video-assisted thoracic surgery requiring OLV in the supine position.

Pulmonary and Respiratory MedicineMedicine
15
Article|28 citations·2018
Efficacy of Palonosetron-Dexamethasone Combination Versus Palonosetron Alone for Preventing Nausea and Vomiting Related to Opioid-Based Analgesia: A Prospective, Randomized, Double-blind Trial
Eun-Ah Cho, Do‐Hyeong Kim, Seokyung Shin, Seung Hyun Kim, Young Jun Oh, Yong Seon Choi
SJR Q2International Journal of Medical SciencesOA

<b>Background</b>: The efficacy of dexamethasone plus palonosetron for postoperative nausea and vomiting (PONV) prophylaxis is not firmly established. This randomized, double-blind, controlled study evaluated whether the combination was superior to palonosetron alone in preventing PONV in patients receiving intravenous patient-controlled analgesia (IV-PCA) after upper extremity surgery. <b>Methods</b>: A total of 202 patients undergoing upper extremity surgery were randomly assigned to group P (

SurgeryMedicine

Research Areas

SurgeryCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineAnesthesiology and Pain MedicineRadiology, Nuclear Medicine and ImagingGeneral Health Professions

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