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Young Han Kim

Yonsei University · 医学

研究室紹介

Professor Young Han Kim's research lab focuses on maternal-fetal medicine and obstetric complications, with a strong emphasis on understanding and predicting pre-eclampsia, preeclampsia-related biomarkers, and perinatal outcomes in twin pregnancies. The lab investigates inflammatory markers such as high-sensitivity C-reactive protein (hsCRP) and platelet indices (e.g., PLR, MPV, PDW) to improve diagnostic and prognostic accuracy in pregnancy disorders. Additionally, the lab explores the impact of reproductive technologies and chorionicity on twin pregnancy outcomes, and examines infectious agents like Ureaplasma urealyticum in adverse pregnancy outcomes. A minor but notable interest in thoracic oncology is reflected in studies on pulmonary nodule malignancy risk in lung cancer patients. The lab integrates clinical data with laboratory biomarkers to enhance maternal and fetal health outcomes through evidence-based medicine and early detection strategies.

pre-eclampsiahsCRPtwin pregnancyplatelet indicesperinatal outcomes

Research Overview

Papers
443
Total Citations
6,254
Papers (5y)
43
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
43total
2021
2022
2023
2024
2025
Citations per year (5y)
309total
20212022202320242025

Selected Papers

15
1
Article|515 citations·2005
Development of a metal recovery process from Li-ion battery wastes
Shun Myung Shin, Nak Hyoung Kim, Jeong-Soo Sohn, Dong Hyo Yang, Young Han Kim
SJR Q1Hydrometallurgy
Mechanical EngineeringEngineering
2
Article|244 citations·1987
Anterior openbite and its treatment with multiloop edgewise archwire.
Young Han Kim
PubMed

Etiologies and various treatment modalities regarding anterior openbite are discussed to elucidate the pros and cons of different approaches, with emphasis on understanding of the true nature of anterior openbite. Subjective interpretation in a diagnosis invariably leads into an erroneous description of a malocclusion, which can lead to a disastrous result. Cognizance of the anatomy, histology, physiology, and dynamics of orthodontic mechanotherapy can bring most openbite malocclusions into the

DermatologyMedicine
3
Article|77 citations·2013
Co-infection with vaginalUreaplasma urealyticumandMycoplasma hominisincreases adverse pregnancy outcomes in patients with preterm labor or preterm premature rupture of membranes
Dong-Wook Kwak, Han Sung Hwang, Ja‐Young Kwon, Yong-Won Park, Young Han Kim
SJR Q2The Journal of Maternal-Fetal & Neonatal MedicineOA

Vaginal MH tends to be detected with UU, and patients carrying both organisms simultaneously had more severe adverse pregnancy outcomes compared to patients in preterm labor or PPROM who were only positive for UU.

MicrobiologyImmunology and Microbiology
4
Article|76 citations·2007
Maternal serum highly sensitive C‐reactive protein in normal pregnancy and pre‐eclampsia
Han Sung Hwang, Ja‐Young Kwon, M.A. Kim, Yae Won Park, Young Han Kim
SJR Q1International Journal of Gynecology & ObstetricsOA

OBJECTIVE: To establish reference values for highly sensitive C-reactive protein (hsCRP) in normal pregnancy and determine whether disease severity could be predicted by serum hsCRP concentration in women with severe pre-eclampsia (PE). METHODS: Blood samples were collected from 25 pregnant women with severe PE and 202 healthy pregnant women who were divided into 4 groups by pregnancy duration. Levels of hsCRP were determined by the immunonephelometric method. Mean arterial pressure, time betwee

Obstetrics and GynecologyMedicine
5
Article|62 citations·2011
Obstetric and Perinatal Outcomes of Dichorionic Twin Pregnancies According to Methods of Conception: Spontaneous Versus In-Vitro Fertilization
Hyoin Yang, Young Sik Choi, Ka Hyun Nam, Ja‐Young Kwon, Yong Won Park, Young Han Kim
SJR Q3Twin Research and Human GeneticsOA

We have observed the inconsistent findings from various studies on twin pregnancy outcomes obtained by assisted reproductive technology and spontaneous conception. In most studies, however, the concrete chorionicity, regarded as a confounding factor for predicting the perinatal outcomes of twin pregnancies, has not been determined. The purpose of this study was to compare obstetric and perinatal outcomes of only the dichorionic twin pregnancies according to the methods of conception: spontaneous

Pediatrics, Perinatology and Child HealthMedicine
6
Article|58 citations·2015
HbA1c for diagnosis and prognosis of gestational diabetes mellitus
Soon Sung Kwon, Ja‐Young Kwon, Yong-Won Park, Young Han Kim, Jong‐Baeck Lim
SJR Q1Diabetes Research and Clinical PracticeOA
Obstetrics and GynecologyMedicine
7
Article|51 citations·2003
Application of a fully thermally coupled distillation column for fractionation process in naphtha reforming plant
Ju Yeong Lee, Young Han Kim, Kyu Suk Hwang
SJR Q1Chemical Engineering and Processing - Process Intensification
Control and Systems EngineeringEngineering
8
Article|51 citations·2018
Clinical significance of platelet‐to‐lymphocyte ratio in women with preeclampsia
Min‐A Kim, Gwan Hee Han, Ja‐Young Kwon, Young Han Kim
SJR Q2American Journal of Reproductive ImmunologyOA

PROBLEM: Preeclampsia (PE) is a serious pregnancy complication leading to high maternal, perinatal morbidity, and mortality. We aimed to investigate the clinical effectiveness of the platelet-to-lymphocyte ratio (PLR) in women with PE and compare this measurement to platelet indices as a diagnostic and prognostic marker of PE. METHOD OF STUDY: A total of 471 healthy pregnant women, 126 women diagnosed with mild PE, and 227 with severe PE were included in this retrospective study. We analyzed PLR

OncologyMedicine
9
Review|49 citations·2002
Small Pulmonary Nodules on CT Accompanying Surgically Resectable Lung Cancer: Likelihood of Malignancy
Young Han Kim, Kyung Soo Lee, Steven L. Primack, Hojoong Kim, O Jung Kwon, Tae Sung Kim, Eun A. Kim, Young Tae Kim, Young Mog Shim
SJR Q2Journal of Thoracic Imaging

The aim of this study was to determine the likelihood of malignancy in small nodules in the nonprimary lobe in patients with resectable bronchogenic carcinoma. In 141 patients who underwent curative resection of bronchogenic carcinoma and had adequate follow-up CT examinations, the presence of small nodules in the nonprimary lobe preoperatively and change of preexisting nodules, if any, was assessed. The criteria used to determine benignity of a nodule was stability or decrease in size for 24 mo

Pulmonary and Respiratory MedicineMedicine
10
Article|48 citations·2005
Vaginal fluid β‐human chorionic gonadotropin level in the diagnosis of premature rupture of membranes
Young Han Kim, Yong-Won Park, Han Sung Kwon, Ja‐Young Kwon, Bok‐Ja Kim
SJR Q1Acta Obstetricia Et Gynecologica ScandinavicaOA

BACKGROUND: To determine whether the measurement of beta-human chorionic gonadotropin (beta-HCG) level in the vaginal washing fluid could be useful for the diagnosis of premature rupture of membranes. METHODS: Totally, 120 pregnant women were enrolled in this study. Subjects were divided into four groups [group I, no preterm labor and term delivery (n = 38); group II, preterm labor and term delivery (n = 12); group III, preterm labor and consequent premature delivery (n = 24); group IV, preterm

EpidemiologyMedicine
11
Review|48 citations·2021
Reproductive, Obstetric and Neonatal Outcomes in Women with Congenital Uterine Anomalies: A Systematic Review and Meta-Analysis
Min‐A Kim, Hyo Sun Kim, Young Han Kim
SJR Q1Journal of Clinical MedicineOA

Congenital uterine anomalies (CUA) may influence reproductive performance, resulting in adverse pregnancy associated complications. This study aimed to assess the association of CUA subtypes with reproductive, obstetric, and perinatal outcomes. We performed a systematic search of the MEDLINE, EMBASE, and Cochrane libraries for studies comparing pregnancy outcomes between women with CUA and those with a normal uterus. The random effects model was used to estimate the odds ratios (ORs) with a 95%

Obstetrics and GynecologyMedicine
12
Article|43 citations·2019
MicroRNA-548 regulates high mobility group box 1 expression in patients with preterm birth and chorioamnionitis
Ga‐Hyun Son, Youngmi Kim, Jae Jun Lee, Keun‐Young Lee, Heejin Ham, Ji‐Eun Song, Sung Taek Park, Young Han Kim, Young Han Kim, Young Han Kim
SJR Q1Scientific ReportsOA

High mobility group box 1 (HMGB1) is a prototypic alarmin and plays an important role in the pathogenesis of inflammatory process in spontaneous preterm birth. This study was conducted to compare the levels of HMGB1 in amniotic fluid and amnion membranes in women with chorioamnionitis/intra-amniotic inflammation to the levels in healthy controls. We also aimed to elucidate the involvement of microRNA-548 (miR-548) in regulating HMGB1 expression and its function in human amniotic epithelial cells

Pulmonary and Respiratory MedicineMedicine
13
Article|39 citations·2017
The Delta Neutrophil Index as a predictive marker of histological chorioamnionitis in patients with preterm premature rupture of membranes: A retrospective study
Hee Young Cho, Inkyung Jung, Ja‐Young Kwon, So Jung Kim, Yong Won Park, Young Han Kim
SJR Q1PLoS ONEOA

BACKGROUND: Histological chorioamnionitis (HCA) is related to perinatal morbidity. However, there is no definite diagnostic method for detecting chorioamnionitis before delivery. METHODS: We evaluated whether the delta neutrophil index (DNI) was an effective early marker of HCA in patients with preterm premature rupture of membranes (PPROM). We retrospectively evaluated 149 women diagnosed with PPROM (gestational age, 20+0 to 36+6 weeks) at Severance Hospital from January 2013 to December 2014.

EpidemiologyMedicine
14
Article|34 citations·2005
A new fully thermally coupled distillation column with postfractionator
Young Han Kim
SJR Q1Chemical Engineering and Processing - Process Intensification
Control and Systems EngineeringEngineering
15
Article|34 citations·2001
Structural Design of Extended Fully Thermally Coupled Distillation Columns
Young Han Kim
SJR Q1Industrial & Engineering Chemistry Research

A structural design procedure for extended fully thermally coupled distillation columns is proposed and applied to the example quaternary systems of several combinations of relative volatility in order to show the design performance. The procedure gives the optimum structure for a given quaternary separation, and therefore iterative computation encountered in the design using commercial packages is not required. Because of extra degrees of freedom in the design of the columns, various designs ca

Control and Systems EngineeringEngineering

Research Areas

Obstetrics and GynecologyControl and Systems EngineeringBiomedical EngineeringPediatrics, Perinatology and Child HealthEpidemiologyComputer Networks and Communications

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